fibrin has been researched along with Aspergillosis* in 3 studies
1 review(s) available for fibrin and Aspergillosis
Article | Year |
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[Transformation of the fungus ball type pulmonary aspergillosis].
Though the concept of semi-invasive pulmonary aspergillosis was advocated in 1981 by Gefter et al., its histopathological appearance has not yet been reported in detail. Pathological studies on fungus ball type pulmonary aspergillosis (PA) were originally made mainly in regard to related bronchi. Chronic-progressive destructive changes cannot be completely explained from this viewpoint alone. Clinically, since bloody sputum and hemoptysis appeared frequently, further studies on the pulmonary vasculature were considered necessary. In the resected lungs of 3 cases of semi-invasive pulmonary aspergillosis, the pathological features of pulmonary vasculature were characterized by numerous fungal clots within pulmonary arteries and veins, marked destruction of pulmonary blood vessels and extensive intravascular fibrin deposition. Intravascular fibrin deposition causes stasis of blood flow, promotes intravascular proliferation of aspergilli and probably accelerates pulmonary destruction caused by blood stasis. Important pathological findings of fungus ball type pulmonary aspergillosis of the semi-invasive subtype with clinical aspects of chronic-progressive lung destruction caused by severe inflammation, were reported for both the vascular and the bronchial system. Topics: Adult; Aspergillosis; Aspergillus; Female; Fibrin; Humans; Lung Diseases, Fungal; Male; Middle Aged; Pulmonary Artery; Pulmonary Veins | 2000 |
2 other study(ies) available for fibrin and Aspergillosis
Article | Year |
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[Developmental mechanism of the "lung ball"--with reference to the pathological findings of the lung in two resected cases].
The lung ball is a special type of pulmonary aspergillosis (PA) occurring often after chemotherapy for leukemia. Histologically the ball, with air crescent sign on roentgenogram, is compatible with necrotizing lung tissue admixed with Aspergilli. The lung ball differs entirely from the common "fungus ball" in its quality, though they are similar in roentgenological appearances. The present two cases were leukemia which showed pulmonary findings in their therapeutic course, resulting in lung resection. In both cases the lung ball was confirmed histopathologically. Immunostaining of the lung tissue for neutrophil elastase showed elastase in various sites in the bronchial wall, pulmonary blood vessels (artery, vein) and cavitary wall. In our previous studies, much importance was attached to the disturbance of the pulmonary circulation caused by fibrin deposition as a factor in the developmental course of the fungus ball type aspergillosis (semi-invasive type). The circulatory disturbance of the lung was recognized also in the present cases. This two-way destruction of the pulmonary tissue, resulting from both neutrophil elastase activities and pulmonary circulatory disturbances, were regarded as the most important factor for the development of the lung ball. There are few studies on aspergillar lung ball with regard to the above respects. Topics: Aged; Aspergillosis; Diagnosis, Differential; Female; Fibrin; Humans; Leukemia; Leukocyte Elastase; Lung; Lung Diseases, Fungal; Male; Middle Aged; Neutrophils; Pneumonectomy; Radiography, Thoracic | 2004 |
Systemic aspergillus infection: report of a fatal case nine months after renal homograft transplantation.
Topics: Arteries; Aspergillosis; Fibrin; Histocytochemistry; Humans; Kidney Glomerulus; Kidney Transplantation; Male; Meninges; Middle Aged; Postoperative Complications; Transplantation, Homologous | 1971 |