Page last updated: 2024-08-23

fialuridine and Acute Liver Injury, Drug-Induced

fialuridine has been researched along with Acute Liver Injury, Drug-Induced in 14 studies

Research

Studies (14)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	5 (35.71)	18.2507
2000's	0 (0.00)	29.6817
2010's	8 (57.14)	24.3611
2020's	1 (7.14)	2.80

Authors

Authors	Studies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S	1
Ding, D; Fang, H; Kelly, R; Liu, Z; Shi, Q; Tong, W	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Dixon, D; Fallon, JK; Liu, J; Mosedale, M; Nautiyal, M; Qasem, RJ; Smith, PC; Wolf, KK	1
Amberntsson, S; Andersson, LC; Cairns, J; Chouhan, B; Darnell, M; Ewart, L; Foster, AJ; Hamilton, GA; Jang, KJ; Kodella, K; Lazic, SE; Morgan, P; Petropolis, DB; Regan, SL; Rollison, H; Rubins, JE; Srivastava, A; Williams, D	1
Bell, CC; Dankers, AC; Ellis, E; Fredriksson Puigvert, L; Goldring, CE; Hendriks, DF; Ingelman-Sundberg, M; Jacobs, F; Jenkins, RE; Kitteringham, NR; Lauschke, VM; Mkrtchian, S; Moro, SM; Nordling, Å; Park, BK; Renblom, A; Sison-Young, RL; Snoeys, J; Walsh, J	1
Marwick, C	2
Stone, R	1
Marshall, E	1
Gaffey, MJ; Hoofnagle, JH; Kleiner, DE; McKenzie, R; Nichols, L; Sallie, R; Straus, SE; Tsokos, M	1

Reviews

1 review(s) available for fialuridine and Acute Liver Injury, Drug-Induced

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

13 other study(ies) available for fialuridine and Acute Liver Injury, Drug-Induced

Article	Year
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors	2012
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). PLoS computational biology, 2011, Volume: 7, Issue:12 Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Models, Biological; Predictive Value of Tests	2011
Characterization of primary mouse hepatocyte spheroids as a model system to support investigations of drug-induced liver injury. Toxicology in vitro : an international journal published in association with BIBRA, 2021, Volume: 70 Topics: Acetaminophen; Adenosine Triphosphate; Albumins; Animals; Arabinofuranosyluracil; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Female; Hepatocytes; Male; Mice, Inbred C57BL; Models, Biological; Phenylacetates; Proteomics; Spheroids, Cellular; Sulfonamides; Tolvaptan; Transcriptome	2021
Integrated in vitro models for hepatic safety and metabolism: evaluation of a human Liver-Chip and liver spheroid. Archives of toxicology, 2019, Volume: 93, Issue:4 Topics: Acetaminophen; Arabinofuranosyluracil; Biomarkers; Cell Culture Techniques; Cell Survival; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Glutathione Transferase; Hepatocytes; Humans; Liver; Models, Biological; Spheroids, Cellular	2019
Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease. Scientific reports, 2016, 05-04, Volume: 6 Topics: Arabinofuranosyluracil; Cells, Cultured; Chemical and Drug Induced Liver Injury; Hepatocytes; Humans; Models, Biological; Proof of Concept Study; Proteome; Spheroids, Cellular	2016
IOM panel exonerates researchers in FIAU deaths. JAMA, 1995, Apr-19, Volume: 273, Issue:15 Topics: Antiviral Agents; Arabinofuranosyluracil; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Drugs, Investigational; Humans; Liver Diseases; Malpractice; National Academies of Science, Engineering, and Medicine, U.S., Health and Medicine Division; United States	1995
Panel clears NIH in patient deaths. Science (New York, N.Y.), 1995, Mar-24, Volume: 267, Issue:5205 Topics: Antiviral Agents; Arabinofuranosyluracil; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Humans; National Academies of Science, Engineering, and Medicine, U.S., Health and Medicine Division; National Institutes of Health (U.S.); United States; United States Food and Drug Administration	1995
NIH panel report of 'no flaws' in FIAU trial at variance with FDA report, new probe planned. JAMA, 1994, Jul-06, Volume: 272, Issue:1 Topics: Antiviral Agents; Arabinofuranosyluracil; Cause of Death; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Hepatitis B; Hepatitis, Chronic; Humans; Liver Diseases; National Institutes of Health (U.S.); Scientific Misconduct; United States; United States Food and Drug Administration	1994
Hepatitis study. Drug trial deaths deemed unavoidable. Science (New York, N.Y.), 1994, Jun-10, Volume: 264, Issue:5165 Topics: Antiviral Agents; Arabinofuranosyluracil; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Federal Government; Government Regulation; Hepatitis B; Humans; National Institutes of Health (U.S.); Pancreatic Diseases; Research Subjects; United States; United States Food and Drug Administration	1994
Histopathologic changes associated with fialuridine hepatotoxicity. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 1997, Volume: 10, Issue:3 Topics: Adult; Antiviral Agents; Arabinofuranosyluracil; Chemical and Drug Induced Liver Injury; Chronic Disease; Clinical Trials, Phase II as Topic; Female; Hepatitis B; Humans; Liver; Male; Middle Aged; Randomized Controlled Trials as Topic	1997