Page last updated: 2024-10-31

fg 7142 and Disease Models, Animal

fg 7142 has been researched along with Disease Models, Animal in 24 studies

FG 7142: benzodiazepine receptor agonist

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
"The protective and adverse effect potentials of levetiracetam ((S)-alpha-ethyl-2-oxo-pyrrolidine acetamide) in rodent models of seizures and epilepsy were compared with the profile of several currently prescribed and newly developed antiepileptic drugs."7.70Evidence for a unique profile of levetiracetam in rodent models of seizures and epilepsy. ( Gobert, J; Klitgaard, H; Matagne, A; Wülfert, E, 1998)
"Benzodiazepine withdrawal, spontaneous or precipitated by the receptor antagonist, flumazenil, produces anxiety that can be measured in animal models."4.78The benzodiazepines: anxiolytic and withdrawal effects. ( Little, HJ, 1991)
"The protective and adverse effect potentials of levetiracetam ((S)-alpha-ethyl-2-oxo-pyrrolidine acetamide) in rodent models of seizures and epilepsy were compared with the profile of several currently prescribed and newly developed antiepileptic drugs."3.70Evidence for a unique profile of levetiracetam in rodent models of seizures and epilepsy. ( Gobert, J; Klitgaard, H; Matagne, A; Wülfert, E, 1998)
"Post-traumatic stress disorder (PTSD) is an anxiety disorder that not only affects mental health, but may also affect bone health."1.38Lasting consequences of traumatic events on behavioral and skeletal parameters in a mouse model for post-traumatic stress disorder (PTSD). ( Johnson, PJ; Kesavan, C; Mohan, S; Watt, H; Wergedal, JE; Yu, H, 2012)
"In this study, the effect of the chronic administration of the benzodiazepine (BZD) receptor ligand FG 7142 on the rat conflict test was examined."1.27Long-lasting proconflict effect induced by chronic administration of the beta-carboline derivative FG 7142. ( Biggio, G; Corda, MG; Gatta, F; Giorgi, O, 1985)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.33)18.7374
1990's5 (20.83)18.2507
2000's4 (16.67)29.6817
2010's12 (50.00)24.3611
2020's1 (4.17)2.80

Authors

AuthorsStudies
Solinski, HJ1
Dranchak, P1
Oliphant, E1
Gu, X1
Earnest, TW1
Braisted, J1
Inglese, J1
Hoon, MA1
Abrams, RPM1
Yasgar, A1
Teramoto, T1
Lee, MH1
Dorjsuren, D1
Eastman, RT1
Malik, N1
Zakharov, AV1
Li, W1
Bachani, M1
Brimacombe, K1
Steiner, JP1
Hall, MD1
Balasubramanian, A1
Jadhav, A1
Padmanabhan, R1
Simeonov, A1
Nath, A1
Stuart, SA2
Butler, P2
Munafò, MR2
Nutt, DJ2
Robinson, ES2
Yeung, M1
Lu, L1
Hughes, AM1
Treit, D1
Dickson, CT1
Kato, Y1
Gokan, H1
Oh-Nishi, A1
Suhara, T1
Watanabe, S1
Minamimoto, T1
Park, J1
Wood, J1
Bondi, C1
Del Arco, A1
Moghaddam, B1
Yuan, X1
Devine, DP1
Dagan, SY1
Tsoory, MM1
Fainzilber, M1
Panayotis, N1
Sink, KS1
Segovia, KN1
Sink, J1
Randall, PA1
Collins, LE1
Correa, M1
Markus, EJ1
Vemuri, VK1
Makriyannis, A1
Salamone, JD1
Freeman-Daniels, E1
Beck, SG1
Kirby, LG1
Zheng, Y1
Cheung, I1
Smith, PF1
Yu, H1
Watt, H1
Kesavan, C1
Johnson, PJ1
Wergedal, JE1
Mohan, S1
Jelen, P1
Soltysik, S1
Zagrodzka, J1
Sena, LM1
Bueno, C1
Pobbe, RL1
Andrade, TG1
Zangrossi, H1
Viana, MB1
Ago, Y1
Takahashi, K1
Nakamura, S1
Hashimoto, H1
Baba, A1
Matsuda, T1
Crawley, JN1
Skolnick, P1
Paul, SM1
Wu, WJ1
Pruett, SB1
Klitgaard, H1
Matagne, A1
Gobert, J1
Wülfert, E1
Jones, N1
Duxon, MS1
King, SM1
Kaltwasser, MT1
Little, HJ1
Piot, O1
Betschart, J1
Stutzmann, JM1
Blanchard, JC1
Corda, MG1
Giorgi, O1
Gatta, F1
Biggio, G1

Reviews

1 review available for fg 7142 and Disease Models, Animal

ArticleYear
The benzodiazepines: anxiolytic and withdrawal effects.
    Neuropeptides, 1991, Volume: 19 Suppl

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Carbolines; Diazepam; Disease Models, Animal; Ethanol; Flumaz

1991

Other Studies

23 other studies available for fg 7142 and Disease Models, Animal

ArticleYear
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
    Science translational medicine, 2019, 07-10, Volume: 11, Issue:500

    Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S

2019
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr

2020
A translational rodent assay of affective biases in depression and antidepressant therapy.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2013, Volume: 38, Issue:9

    Topics: Affect; Animals; Antidepressive Agents; Appetite Depressants; Cannabinoid Receptor Antagonists; Carb

2013
FG7142, yohimbine, and βCCE produce anxiogenic-like effects in the elevated plus-maze but do not affect brainstem activated hippocampal theta.
    Neuropharmacology, 2013, Volume: 75

    Topics: Adrenergic alpha-2 Receptor Antagonists; Analysis of Variance; Animals; Anxiety; Biophysics; Brain S

2013
Vocalizations associated with anxiety and fear in the common marmoset (Callithrix jacchus).
    Behavioural brain research, 2014, Dec-15, Volume: 275

    Topics: Acoustic Stimulation; Analysis of Variance; Animals; Anxiety; Auditory Perception; Callithrix; Carbo

2014
Distinct Neuropsychological Mechanisms May Explain Delayed- Versus Rapid-Onset Antidepressant Efficacy.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2015, Volume: 40, Issue:9

    Topics: Animals; Antidepressive Agents; Association Learning; Brain; Cannabinoid Receptor Antagonists; Carbo

2015
Anxiety Evokes Hypofrontality and Disrupts Rule-Relevant Encoding by Dorsomedial Prefrontal Cortex Neurons.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016, Mar-16, Volume: 36, Issue:11

    Topics: Action Potentials; Animals; Anxiety; Attention; Carbolines; Disease Models, Animal; GABA Antagonists

2016
The role of anxiety in vulnerability for self-injurious behaviour: studies in a rodent model.
    Behavioural brain research, 2016, 09-15, Volume: 311

    Topics: Analysis of Variance; Animals; Anxiety; Carbolines; Disease Models, Animal; Disease Susceptibility;

2016
COLORcation: A new application to phenotype exploratory behavior models of anxiety in mice.
    Journal of neuroscience methods, 2016, 09-01, Volume: 270

    Topics: Algorithms; Analysis of Variance; Animals; Anxiety; Carbolines; Disease Models, Animal; Exploratory

2016
Potential anxiogenic effects of cannabinoid CB1 receptor antagonists/inverse agonists in rats: comparisons between AM4113, AM251, and the benzodiazepine inverse agonist FG-7142.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2010, Volume: 20, Issue:2

    Topics: Animals; Anxiety; Brain; Carbolines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug

2010
Cellular correlates of anxiety in CA1 hippocampal pyramidal cells of 5-HT1A receptor knockout mice.
    Psychopharmacology, 2011, Volume: 213, Issue:2-3

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Carbolines; Diazepam; Disease Models, Animal; Excitatory Post

2011
Performance in anxiety and spatial memory tests following bilateral vestibular loss in the rat and effects of anxiolytic and anxiogenic drugs.
    Behavioural brain research, 2012, Nov-01, Volume: 235, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Buspirone; Carbolines; Disease Models, Animal; GABA Antagonis

2012
Lasting consequences of traumatic events on behavioral and skeletal parameters in a mouse model for post-traumatic stress disorder (PTSD).
    PloS one, 2012, Volume: 7, Issue:8

    Topics: Animals; Anxiety; Behavior, Animal; Bone and Bones; Bone Density; Carbolines; Disease Models, Animal

2012
22-kHz ultrasonic vocalization in rats as an index of anxiety but not fear: behavioral and pharmacological modulation of affective state.
    Behavioural brain research, 2003, Apr-17, Volume: 141, Issue:1

    Topics: Animals; Anxiety; Behavior, Animal; Buspirone; Carbolines; Conditioning, Classical; Diagnosis, Diffe

2003
The dorsal raphe nucleus exerts opposed control on generalized anxiety and panic-related defensive responses in rats.
    Behavioural brain research, 2003, Jun-16, Volume: 142, Issue:1-2

    Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anxiety; Avoidance Learnin

2003
Anxiety-like and exploratory behaviors of isolation-reared mice in the staircase test.
    Journal of pharmacological sciences, 2007, Volume: 104, Issue:2

    Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Carbolines; Central N

2007
Absence of intrinsic antagonist actions of benzodiazepine antagonists on an exploratory model of anxiety in the mouse.
    Neuropharmacology, 1984, Volume: 23, Issue:5

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Benzodiazepinones; Carbolines; Disease Models, Animal; Dose-R

1984
Suppression of splenic natural killer cell activity in a mouse model for binge drinking. II. Role of the neuroendocrine system.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 278, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alcoholism; Animals; Azides; Benzodiazepi

1996
Evidence for a unique profile of levetiracetam in rodent models of seizures and epilepsy.
    European journal of pharmacology, 1998, Jul-24, Volume: 353, Issue:2-3

    Topics: Amygdala; Animals; Anticonvulsants; Behavior, Animal; Carbolines; Convulsants; Diazepam; Disease Mod

1998
Ethopharmacological analysis of the unstable elevated exposed plus maze, a novel model of extreme anxiety: predictive validity and sensitivity to anxiogenic agents.
    Psychopharmacology, 2002, Volume: 161, Issue:3

    Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Caffeine; Ca

2002
Acoustic startle induced ultrasonic vocalization in the rat: a novel animal model of anxiety?
    Behavioural brain research, 1991, May-15, Volume: 43, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Appetite Depressants; Arousal; Carbolines; Diazepam; Disease

1991
Cyclopyrrolones, unlike some benzodiazepines, do not induce physical dependence in mice.
    Neuroscience letters, 1990, Sep-04, Volume: 117, Issue:1-2

    Topics: Animals; Azabicyclo Compounds; Carbolines; Convulsants; Diazepam; Disease Models, Animal; Flunitraze

1990
Long-lasting proconflict effect induced by chronic administration of the beta-carboline derivative FG 7142.
    Neuroscience letters, 1985, Dec-04, Volume: 62, Issue:2

    Topics: Animals; Anxiety; Benzodiazepinones; Carbolines; Conflict, Psychological; Disease Models, Animal; Dr

1985