fg 7142 has been researched along with Ataxia in 2 studies
FG 7142: benzodiazepine receptor agonist
Ataxia: Impairment of the ability to perform smoothly coordinated voluntary movements. This condition may affect the limbs, trunk, eyes, pharynx, larynx, and other structures. Ataxia may result from impaired sensory or motor function. Sensory ataxia may result from posterior column injury or PERIPHERAL NERVE DISEASES. Motor ataxia may be associated with CEREBELLAR DISEASES; CEREBRAL CORTEX diseases; THALAMIC DISEASES; BASAL GANGLIA DISEASES; injury to the RED NUCLEUS; and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Acute nitrendipine significantly increased the latency of seizures in response to the partial benzodiazepine inverse agonist FG7142 during barbiturate withdrawal, but there was no effect on the seizure incidence in response to bicuculline." | 3.69 | Dihydropyridine-sensitive calcium channels and barbiturate tolerance and withdrawal. ( Brown, J; Butterworth, AR; Little, HJ; Rabbani, M, 1994) |
| "However, midazolam-induced ataxia was significantly modified 3-1/2 h following both restraint and FG 7142 exposure." | 1.30 | FG 7142- and restraint-induced alterations in the ataxic effects of alcohol and midazolam in rats are time dependent. ( Austin, M; Brown, PL; Drugan, RC; Mammola, B; Myles, V, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rabbani, M | 1 |
| Brown, J | 1 |
| Butterworth, AR | 1 |
| Little, HJ | 1 |
| Austin, M | 1 |
| Myles, V | 1 |
| Brown, PL | 1 |
| Mammola, B | 1 |
| Drugan, RC | 1 |
2 other studies available for fg 7142 and Ataxia
| Article | Year |
|---|---|
Dihydropyridine-sensitive calcium channels and barbiturate tolerance and withdrawal.
Topics: Anesthesia, General; Animals; Ataxia; Barbiturates; Bicuculline; Calcium Channels; Carbolines; Dihyd | 1994 |
FG 7142- and restraint-induced alterations in the ataxic effects of alcohol and midazolam in rats are time dependent.
Topics: Animals; Ataxia; Carbolines; Ethanol; GABA Antagonists; GABA Modulators; Male; Midazolam; Motor Acti | 1999 |