fexofenadine has been researched along with Renal Insufficiency, Chronic in 2 studies
fexofenadine: a second generation antihistamine; metabolite of the antihistaminic drug terfenadine; structure in first source; RN refers to HCl
fexofenadine : A piperidine-based anti-histamine compound.
Renal Insufficiency, Chronic: Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Midazolam AUC was significantly higher in the HD group (382." | 1.42 | Effect of CKD and dialysis modality on exposure to drugs cleared by nonrenal mechanisms. ( Asher, LJ; Feere, DA; House, AA; Knauer, MJ; Nolin, TD; Thomson, BK; Urquhart, BL; Velenosi, TJ, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Joy, MS | 1 |
| Frye, RF | 1 |
| Nolin, TD | 2 |
| Roberts, BV | 1 |
| La, MK | 1 |
| Wang, J | 1 |
| Brouwer, KL | 1 |
| Dooley, MA | 1 |
| Falk, RJ | 1 |
| Thomson, BK | 1 |
| Velenosi, TJ | 1 |
| Feere, DA | 1 |
| Knauer, MJ | 1 |
| Asher, LJ | 1 |
| House, AA | 1 |
| Urquhart, BL | 1 |
1 trial available for fexofenadine and Renal Insufficiency, Chronic
| Article | Year |
|---|---|
In vivo alterations in drug metabolism and transport pathways in patients with chronic kidney diseases.
Topics: Adult; Aged; Aged, 80 and over; Biological Transport; Breath Tests; Case-Control Studies; Cytochrome | 2014 |
1 other study available for fexofenadine and Renal Insufficiency, Chronic
| Article | Year |
|---|---|
Effect of CKD and dialysis modality on exposure to drugs cleared by nonrenal mechanisms.
Topics: Adult; Aged; Aged, 80 and over; Anti-Allergic Agents; Anti-Anxiety Agents; Cytochrome P-450 CYP3A; F | 2015 |