Page last updated: 2024-10-27

fexofenadine and Long QT Syndrome

fexofenadine has been researched along with Long QT Syndrome in 9 studies

fexofenadine: a second generation antihistamine; metabolite of the antihistaminic drug terfenadine; structure in first source; RN refers to HCl
fexofenadine : A piperidine-based anti-histamine compound.

Long QT Syndrome: A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.

Research Excerpts

ExcerptRelevanceReference
"Arsenic trioxide (As2O3) has been verified as a breakthrough in the management of acute promyelocytic leukemia in recent decades."3.85Mechanism of As2O3-Induced Action Potential Prolongation and Using hiPS-CMs to Evaluate the Rescue Efficacy of Drugs With Different Rescue Mechanism. ( Feng, L; Li, B; Li, F; Liu, Y; Shi, Y; Wang, J; Yan, M, 2017)
"The long QT syndrome is a rare disease."1.33Long QT syndrome in a patient with allergic rhinoconjunctivitis and auto-immune diabetes: focus on the choice of anti-H1 drugs. ( Codreanu, A; de Chillou, C; Moneret-Vautrin, DA, 2006)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (22.22)18.2507
2000's6 (66.67)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cavalli, A1
Poluzzi, E1
De Ponti, F1
Recanatini, M1
Yan, M1
Feng, L1
Shi, Y1
Wang, J1
Liu, Y1
Li, F1
Li, B1
Couderc, JP1
Lehman, JM1
Blaiss, MS1
Moneret-Vautrin, DA1
de Chillou, C1
Codreanu, A1
Pinto, YM1
van Gelder, IC1
Heeringa, M1
Crijns, HJ1
Shuster, J1
Dhar, S1
Hazra, PK1
Malakar, S1
Mistri, G1
Rajamani, S1
Anderson, CL1
Anson, BD1
January, CT1

Reviews

1 review available for fexofenadine and Long QT Syndrome

ArticleYear
Selecting the optimal oral antihistamine for patients with allergic rhinitis.
    Drugs, 2006, Volume: 66, Issue:18

    Topics: Administration, Oral; Cardiovascular System; Central Nervous System; Cetirizine; Drug Interactions;

2006

Other Studies

8 other studies available for fexofenadine and Long QT Syndrome

ArticleYear
Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers.
    Journal of medicinal chemistry, 2002, Aug-29, Volume: 45, Issue:18

    Topics: Anti-Arrhythmia Agents; Cation Transport Proteins; Cluster Analysis; Databases, Factual; Ether-A-Go-

2002
Mechanism of As2O3-Induced Action Potential Prolongation and Using hiPS-CMs to Evaluate the Rescue Efficacy of Drugs With Different Rescue Mechanism.
    Toxicological sciences : an official journal of the Society of Toxicology, 2017, 08-01, Volume: 158, Issue:2

    Topics: Action Potentials; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; ERG1 Potassium Channel; HEK2

2017
QT interval prolongation and beyond.
    Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2006, Volume: 11, Issue:4

    Topics: Animals; Anti-Allergic Agents; Dogs; Electrocardiography; Heart Rate; Humans; Long QT Syndrome; Terf

2006
Long QT syndrome in a patient with allergic rhinoconjunctivitis and auto-immune diabetes: focus on the choice of anti-H1 drugs.
    European annals of allergy and clinical immunology, 2006, Volume: 38, Issue:10

    Topics: Adolescent; Adrenergic beta-Antagonists; Anti-Asthmatic Agents; Butyrophenones; Cetirizine; Conjunct

2006
QT lengthening and life-threatening arrhythmias associated with fexofenadine.
    Lancet (London, England), 1999, Mar-20, Volume: 353, Issue:9157

    Topics: Aged; Electrocardiography; Histamine H1 Antagonists; Humans; Long QT Syndrome; Male; Syncope; Tachyc

1999
Fexofenadine and prolonged QT intervals.
    Nursing, 1999, Volume: 29, Issue:9

    Topics: Aged; Drug Monitoring; Electrocardiography; Histamine H1 Antagonists; Humans; Long QT Syndrome; Male

1999
Fexofenadine-induced QT prolongation: a myth or fact?
    The British journal of dermatology, 2000, Volume: 142, Issue:6

    Topics: Controlled Clinical Trials as Topic; Histamine H1 Antagonists; Humans; Long QT Syndrome; Terfenadine

2000
Pharmacological rescue of human K(+) channel long-QT2 mutations: human ether-a-go-go-related gene rescue without block.
    Circulation, 2002, Jun-18, Volume: 105, Issue:24

    Topics: Anti-Arrhythmia Agents; Cell Line; Dose-Response Relationship, Drug; Electric Conductivity; ERG1 Pot

2002