fexofenadine has been researched along with Ischemic Stroke in 1 studies
fexofenadine: a second generation antihistamine; metabolite of the antihistaminic drug terfenadine; structure in first source; RN refers to HCl
fexofenadine : A piperidine-based anti-histamine compound.
Ischemic Stroke: Stroke due to BRAIN ISCHEMIA resulting in interruption or reduction of blood flow to a part of the brain. When obstruction is due to a BLOOD CLOT formed within in a cerebral blood vessel it is a thrombotic stroke. When obstruction is formed elsewhere and moved to block a cerebral blood vessel (see CEREBRAL EMBOLISM) it is referred to as embolic stroke. Wake-up stroke refers to ischemic stroke occurring during sleep while cryptogenic stroke refers to ischemic stroke of unknown origin.
Excerpt | Relevance | Reference |
---|---|---|
"Our data demonstrate that neuroprotective effects of atorvastatin may require central nervous system delivery by Oatp-mediated transport at the blood-brain barrier, a mechanism that persists despite increased cerebrovascular permeability in ischemic stroke." | 8.31 | Oatp (Organic Anion Transporting Polypeptide)-Mediated Transport: A Mechanism for Atorvastatin Neuroprotection in Stroke. ( Betterton, RD; Davis, TP; Lochhead, JJ; Moreno-Rodriguez, VM; Ronaldson, PT; Stanton, JA; Williams, EI, 2023) |
"Our data demonstrate that neuroprotective effects of atorvastatin may require central nervous system delivery by Oatp-mediated transport at the blood-brain barrier, a mechanism that persists despite increased cerebrovascular permeability in ischemic stroke." | 4.31 | Oatp (Organic Anion Transporting Polypeptide)-Mediated Transport: A Mechanism for Atorvastatin Neuroprotection in Stroke. ( Betterton, RD; Davis, TP; Lochhead, JJ; Moreno-Rodriguez, VM; Ronaldson, PT; Stanton, JA; Williams, EI, 2023) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 1 (100.00) | 2.80 |
Authors | Studies |
---|---|
Williams, EI | 1 |
Betterton, RD | 1 |
Stanton, JA | 1 |
Moreno-Rodriguez, VM | 1 |
Lochhead, JJ | 1 |
Davis, TP | 1 |
Ronaldson, PT | 1 |
1 other study available for fexofenadine and Ischemic Stroke
Article | Year |
---|---|
Oatp (Organic Anion Transporting Polypeptide)-Mediated Transport: A Mechanism for Atorvastatin Neuroprotection in Stroke.
Topics: Animals; Atorvastatin; Brain Edema; Infarction, Middle Cerebral Artery; Ischemic Stroke; Male; Neuro | 2023 |