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fexofenadine and Chronic Illness

fexofenadine has been researched along with Chronic Illness in 19 studies

fexofenadine: a second generation antihistamine; metabolite of the antihistaminic drug terfenadine; structure in first source; RN refers to HCl
fexofenadine : A piperidine-based anti-histamine compound.

Research Excerpts

ExcerptRelevanceReference
"H1-antihistamines are the first-line treatment of chronic idiopathic urticaria (CIU), but CIU is occasionally refractory to the conventional treatment doses."9.17Comparison of the efficacy of fexofenadine 120 and 240 mg/day on chronic idiopathic urticaria and histamine-induced skin responses in Japanese populations. ( Kabashima, K; Miyachi, Y; Nakahigashi, K; Tanizaki, H, 2013)
"The present study examined the impact of once-daily fexofenadine hydrochloride (HCl) 180 mg on health-related quality of life (HRQL) in subjects with chronic idiopathic urticaria (CIU)."9.12The effect of fexofenadine hydrochloride on productivity and quality of life in patients with chronic idiopathic urticaria. ( Harding, G; Leahy, MJ; Meeves, S; Shikiar, R; Spector, SL, 2007)
"In this 4-week, multicenter, placebo-controlled study, 439 patients with moderate to severe pruritus and urticaria received 1 of 4 oral doses of fexofenadine HCl (20, 60, 120, or 240 mg twice a day) or placebo."9.09A double-blind, placebo-controlled trial of fexofenadine HCl in the treatment of chronic idiopathic urticaria. ( Finn, AF; Fretwell, R; Kaplan, AP; Long, J; Qu, R, 1999)
"This dose-finding study assessed the safety and efficacy of fexofenadine in chronic idiopathic urticaria."9.09Fexofenadine HCl is safe and effective for treatment of chronic idiopathic urticaria. ( Mason, J; Nelson, HS; Reynolds, R, 2000)
"The effect of 60 mg twice-daily fexofenadine HCl on health-related quality of life and productivity at work, in the classroom, and during daily activities in patients with moderate to severe chronic idiopathic urticaria symptoms was studied in two identical, 4-week, placebo-controlled, multicenter clinical trials."9.09Effect of 60 mg twice-daily fexofenadine HCl on quality of life, work and classroom productivity, and regular activity in patients with chronic idiopathic urticaria. ( Finn, AF; Schoenwetter, WF; Thompson, AK, 2000)
"fexofenadine is clinically effective in the treatment of seasonal allergic rhinitis and chronic idiopathic urticaria for which it is a suitable option for first-line therapy."7.70Fexofenadine: a review of its use in the management of seasonal allergic rhinitis and chronic idiopathic urticaria. ( Jarvis, B; Simpson, K, 2000)
"To evaluate the efficacy and safety of once-daily dosing of fexofenadine hydrochloride, 180 mg, on CIU."6.71Once-daily fexofenadine treatment for chronic idiopathic urticaria: a multicenter, randomized, double-blind, placebo-controlled study. ( Georges, G; Kaplan, AP; Liao, Y; Meeves, S; Spector, SL; Varghese, ST, 2005)
"Fexofenadine is a non-sedating antihistamine indicated for relieving symptoms from allergic conditions with a rapid onset of action without cardiotoxic risks."6.70Multicenter study of the efficacy and safety of fexofenadine 60 mg. twice daily in 108 Thai patients with chronic idiopathic urticaria. ( Aunhachoke, K; Charuwichitratana, S; Gherunpong, N; Gritiyarangsan, P; Janjumratsang, P; Jiamton, S; Korkij, W; Krisadapong, J; Kullavanijaya, P; Kulthanan, K; Kuntiranont, M; Sitakalin, C, 2001)
"Fexofenadine 180 mg is a new antihistamine that is effective in the treatment of chronic urticaria and that has a profile of side effects similar to placebo."6.70[Chronic idiopathic urticaria: effectiveness of fexofenadine. A double-blind, placebo controlled study with 21 patients]. ( Bircher, A; Degonda, M; Helbling, A; Pichler, WJ, 2002)
"Urticaria is a common clinical condition that gives a major concern for physicians and patients alike."5.56Efficacy of Fexofenadine in the Treatment of Chronic Idiopathic Urticaria. ( Akhter, F; Jahan, H; Nandi, AK, 2020)
"H1-antihistamines are the first-line treatment of chronic idiopathic urticaria (CIU), but CIU is occasionally refractory to the conventional treatment doses."5.17Comparison of the efficacy of fexofenadine 120 and 240 mg/day on chronic idiopathic urticaria and histamine-induced skin responses in Japanese populations. ( Kabashima, K; Miyachi, Y; Nakahigashi, K; Tanizaki, H, 2013)
"The present study examined the impact of once-daily fexofenadine hydrochloride (HCl) 180 mg on health-related quality of life (HRQL) in subjects with chronic idiopathic urticaria (CIU)."5.12The effect of fexofenadine hydrochloride on productivity and quality of life in patients with chronic idiopathic urticaria. ( Harding, G; Leahy, MJ; Meeves, S; Shikiar, R; Spector, SL, 2007)
"In this 4-week, multicenter, placebo-controlled study, 439 patients with moderate to severe pruritus and urticaria received 1 of 4 oral doses of fexofenadine HCl (20, 60, 120, or 240 mg twice a day) or placebo."5.09A double-blind, placebo-controlled trial of fexofenadine HCl in the treatment of chronic idiopathic urticaria. ( Finn, AF; Fretwell, R; Kaplan, AP; Long, J; Qu, R, 1999)
"This dose-finding study assessed the safety and efficacy of fexofenadine in chronic idiopathic urticaria."5.09Fexofenadine HCl is safe and effective for treatment of chronic idiopathic urticaria. ( Mason, J; Nelson, HS; Reynolds, R, 2000)
"The effect of 60 mg twice-daily fexofenadine HCl on health-related quality of life and productivity at work, in the classroom, and during daily activities in patients with moderate to severe chronic idiopathic urticaria symptoms was studied in two identical, 4-week, placebo-controlled, multicenter clinical trials."5.09Effect of 60 mg twice-daily fexofenadine HCl on quality of life, work and classroom productivity, and regular activity in patients with chronic idiopathic urticaria. ( Finn, AF; Schoenwetter, WF; Thompson, AK, 2000)
"fexofenadine is clinically effective in the treatment of seasonal allergic rhinitis and chronic idiopathic urticaria for which it is a suitable option for first-line therapy."3.70Fexofenadine: a review of its use in the management of seasonal allergic rhinitis and chronic idiopathic urticaria. ( Jarvis, B; Simpson, K, 2000)
"To evaluate the efficacy and safety of once-daily dosing of fexofenadine hydrochloride, 180 mg, on CIU."2.71Once-daily fexofenadine treatment for chronic idiopathic urticaria: a multicenter, randomized, double-blind, placebo-controlled study. ( Georges, G; Kaplan, AP; Liao, Y; Meeves, S; Spector, SL; Varghese, ST, 2005)
"Fexofenadine is a non-sedating antihistamine indicated for relieving symptoms from allergic conditions with a rapid onset of action without cardiotoxic risks."2.70Multicenter study of the efficacy and safety of fexofenadine 60 mg. twice daily in 108 Thai patients with chronic idiopathic urticaria. ( Aunhachoke, K; Charuwichitratana, S; Gherunpong, N; Gritiyarangsan, P; Janjumratsang, P; Jiamton, S; Korkij, W; Krisadapong, J; Kullavanijaya, P; Kulthanan, K; Kuntiranont, M; Sitakalin, C, 2001)
"Fexofenadine 180 mg is a new antihistamine that is effective in the treatment of chronic urticaria and that has a profile of side effects similar to placebo."2.70[Chronic idiopathic urticaria: effectiveness of fexofenadine. A double-blind, placebo controlled study with 21 patients]. ( Bircher, A; Degonda, M; Helbling, A; Pichler, WJ, 2002)
"Urticaria is a common clinical condition that gives a major concern for physicians and patients alike."1.56Efficacy of Fexofenadine in the Treatment of Chronic Idiopathic Urticaria. ( Akhter, F; Jahan, H; Nandi, AK, 2020)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.26)18.2507
2000's14 (73.68)29.6817
2010's3 (15.79)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Jahan, H1
Akhter, F1
Nandi, AK1
Tanizaki, H2
Nakahigashi, K1
Miyachi, Y2
Kabashima, K2
Koh, SJ1
Kim, JW1
Kim, BG1
Lee, KL1
Chun, J1
Kim, JS1
Yamamoto, Y1
Nakamizo, S1
Otsuka, A1
Chowdhury, BA1
Cassano, N1
Filotico, R1
D'Argento, V1
Filieri, M1
Coviello, C1
Vena, G1
Kawashima, M1
Harada, S1
Tango, T1
Lennox, RD2
Leahy, MJ2
Shikiar, R2
Harding, G2
Leahy, M1
Kaplan, AP2
Spector, SL2
Meeves, S2
Liao, Y1
Varghese, ST1
Georges, G1
Finn, AF2
Fretwell, R1
Qu, R1
Long, J1
Simpson, K1
Jarvis, B1
Nelson, HS1
Reynolds, R1
Mason, J1
Thompson, AK1
Schoenwetter, WF1
Nettis, E1
Dambra, P1
D'Oronzio, L1
Loria, MP1
Ferrannini, A1
Tursi, A1
Amichai, B1
Grunwald, MH1
Brenner, L1
Kulthanan, K1
Gritiyarangsan, P1
Sitakalin, C1
Charuwichitratana, S1
Korkij, W1
Aunhachoke, K1
Janjumratsang, P1
Jiamton, S1
Kuntiranont, M1
Krisadapong, J1
Gherunpong, N1
Kullavanijaya, P1
Degonda, M1
Pichler, WJ1
Bircher, A1
Helbling, A1

Reviews

2 reviews available for fexofenadine and Chronic Illness

ArticleYear
Review of fexofenadine in the treatment of chronic idiopathic urticaria.
    International journal of dermatology, 2002, Volume: 41, Issue:10

    Topics: Anti-Allergic Agents; Asia; Chronic Disease; Humans; North America; Terfenadine; Urticaria

2002
Fexofenadine hydrochloride--a new anti-histaminic drug.
    The Israel Medical Association journal : IMAJ, 2001, Volume: 3, Issue:3

    Topics: Chronic Disease; Clinical Trials as Topic; Drug Interactions; Histamine H1 Antagonists; Humans; Pati

2001

Trials

11 trials available for fexofenadine and Chronic Illness

ArticleYear
Comparison of the efficacy of fexofenadine 120 and 240 mg/day on chronic idiopathic urticaria and histamine-induced skin responses in Japanese populations.
    The Journal of dermatological treatment, 2013, Volume: 24, Issue:6

    Topics: Adult; Chronic Disease; Cross-Over Studies; Double-Blind Method; Female; Histamine; Histamine H1 Ant

2013
Comparison of the efficacy of olopatadine and fexofenadine in chronic idiopathic urticaria patients: a crossover study.
    Pharmacology, 2015, Volume: 95, Issue:1-2

    Topics: Adult; Anti-Allergic Agents; Chronic Disease; Cross-Over Studies; Dibenzoxepins; Female; Histamine H

2015
Validation of the Dermatology Life Quality Index as an outcome measure for urticaria-related quality of life.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2004, Volume: 93, Issue:2

    Topics: Chronic Disease; Dermatology; Dose-Response Relationship, Drug; Double-Blind Method; Histamine H1 An

2004
Once-daily fexofenadine treatment for chronic idiopathic urticaria: a multicenter, randomized, double-blind, placebo-controlled study.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2005, Volume: 94, Issue:6

    Topics: Adolescent; Child; Chronic Disease; Double-Blind Method; Female; Humans; Male; Terfenadine; Urticari

2005
The effect of fexofenadine hydrochloride on productivity and quality of life in patients with chronic idiopathic urticaria.
    Cutis, 2007, Volume: 79, Issue:2

    Topics: Adolescent; Chronic Disease; Double-Blind Method; Efficiency; Female; Histamine H1 Antagonists, Non-

2007
A double-blind, placebo-controlled trial of fexofenadine HCl in the treatment of chronic idiopathic urticaria.
    The Journal of allergy and clinical immunology, 1999, Volume: 104, Issue:5

    Topics: Adolescent; Adult; Aged; Child; Chronic Disease; Double-Blind Method; Female; Histamine H1 Antagonis

1999
Fexofenadine HCl is safe and effective for treatment of chronic idiopathic urticaria.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2000, Volume: 84, Issue:5

    Topics: Adolescent; Adult; Aged; Anti-Allergic Agents; Child; Chronic Disease; Disorders of Excessive Somnol

2000
Effect of 60 mg twice-daily fexofenadine HCl on quality of life, work and classroom productivity, and regular activity in patients with chronic idiopathic urticaria.
    Journal of the American Academy of Dermatology, 2000, Volume: 43, Issue:1 Pt 1

    Topics: Adolescent; Adult; Aged; Chronic Disease; Female; Histamine H1 Antagonists; Humans; Male; Middle Age

2000
Comparison of montelukast and fexofenadine for chronic idiopathic urticaria.
    Archives of dermatology, 2001, Volume: 137, Issue:1

    Topics: Acetates; Adult; Aged; Chronic Disease; Cyclopropanes; Double-Blind Method; Female; Histamine H1 Ant

2001
Multicenter study of the efficacy and safety of fexofenadine 60 mg. twice daily in 108 Thai patients with chronic idiopathic urticaria.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2001, Volume: 84, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Chronic Disease; Female; Histamine H1 Antagonists; Human

2001
[Chronic idiopathic urticaria: effectiveness of fexofenadine. A double-blind, placebo controlled study with 21 patients].
    Praxis, 2002, Apr-10, Volume: 91, Issue:15

    Topics: Adult; Aged; Anti-Allergic Agents; Chronic Disease; Double-Blind Method; Female; Humans; Male; Middl

2002

Other Studies

6 other studies available for fexofenadine and Chronic Illness

ArticleYear
Efficacy of Fexofenadine in the Treatment of Chronic Idiopathic Urticaria.
    Mymensingh medical journal : MMJ, 2020, Volume: 29, Issue:2

    Topics: Adolescent; Bangladesh; Chronic Disease; Chronic Urticaria; Double-Blind Method; Humans; Terfenadine

2020
Fexofenadine regulates nuclear factor-κB signaling and endoplasmic reticulum stress in intestinal epithelial cells and ameliorates acute and chronic colitis in mice.
    The Journal of pharmacology and experimental therapeutics, 2015, Volume: 352, Issue:3

    Topics: Acute Disease; Animals; Chronic Disease; Colitis; Endoplasmic Reticulum Stress; Female; HCT116 Cells

2015
Chronic urticaria and angioedema.
    The New England journal of medicine, 2002, Jul-18, Volume: 347, Issue:3

    Topics: Angioedema; Chronic Disease; Histamine H1 Antagonists; Humans; Terfenadine; Urticaria

2002
In vivo anti-inflammatory effects of fexofenadine in chronic idiopathic urticaria.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2002, Volume: 16, Issue:4

    Topics: Adolescent; Adult; Biopsy, Needle; Case-Control Studies; Chronic Disease; Culture Techniques; E-Sele

2002
Minimal important difference (MID) of the Dermatology Life Quality Index (DLQI): results from patients with chronic idiopathic urticaria.
    Health and quality of life outcomes, 2005, May-20, Volume: 3

    Topics: Adolescent; Adult; Aged; Child; Chronic Disease; Clinical Trials, Phase III as Topic; Data Interpret

2005
Fexofenadine: a review of its use in the management of seasonal allergic rhinitis and chronic idiopathic urticaria.
    Drugs, 2000, Volume: 59, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Anti-Allergic Agents; Chronic Disease; Dose-Response Relati

2000