fexofenadine has been researched along with Brain Edema in 1 studies
fexofenadine: a second generation antihistamine; metabolite of the antihistaminic drug terfenadine; structure in first source; RN refers to HCl
fexofenadine : A piperidine-based anti-histamine compound.
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our data demonstrate that neuroprotective effects of atorvastatin may require central nervous system delivery by Oatp-mediated transport at the blood-brain barrier, a mechanism that persists despite increased cerebrovascular permeability in ischemic stroke." | 8.31 | Oatp (Organic Anion Transporting Polypeptide)-Mediated Transport: A Mechanism for Atorvastatin Neuroprotection in Stroke. ( Betterton, RD; Davis, TP; Lochhead, JJ; Moreno-Rodriguez, VM; Ronaldson, PT; Stanton, JA; Williams, EI, 2023) |
| "Our data demonstrate that neuroprotective effects of atorvastatin may require central nervous system delivery by Oatp-mediated transport at the blood-brain barrier, a mechanism that persists despite increased cerebrovascular permeability in ischemic stroke." | 4.31 | Oatp (Organic Anion Transporting Polypeptide)-Mediated Transport: A Mechanism for Atorvastatin Neuroprotection in Stroke. ( Betterton, RD; Davis, TP; Lochhead, JJ; Moreno-Rodriguez, VM; Ronaldson, PT; Stanton, JA; Williams, EI, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Williams, EI | 1 |
| Betterton, RD | 1 |
| Stanton, JA | 1 |
| Moreno-Rodriguez, VM | 1 |
| Lochhead, JJ | 1 |
| Davis, TP | 1 |
| Ronaldson, PT | 1 |
1 other study available for fexofenadine and Brain Edema
| Article | Year |
|---|---|
Oatp (Organic Anion Transporting Polypeptide)-Mediated Transport: A Mechanism for Atorvastatin Neuroprotection in Stroke.
Topics: Animals; Atorvastatin; Brain Edema; Infarction, Middle Cerebral Artery; Ischemic Stroke; Male; Neuro | 2023 |