fexofenadine has been researched along with Asthma in 13 studies
fexofenadine: a second generation antihistamine; metabolite of the antihistaminic drug terfenadine; structure in first source; RN refers to HCl
fexofenadine : A piperidine-based anti-histamine compound.
Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fourteen atopic patients with mild-to-moderate asthma (forced expiratory volume in 1 second of 76%) completed a double-blind, randomized, crossover study consisting of 3-week treatment blocks of either fluticasone propionate-salmeterol, 250 microg twice daily, or fluticasone propionate alone, 250 microg twice daily, in conjunction with either fexofenadine, 180 mg once daily, or matched placebo." | 9.11 | Addition of fexofenadine to inhaled corticosteroid therapy to reduce inflammatory biomarkers in atopic asthma. ( Fardon, TC; Hodge, MR; Lee, DK; Lipworth, BJ, 2005) |
| "The goal of the study was to determine if pranlukast has effects on the upper and lower airways through a comparison of the effects of fexofenadine and pranlukast on airway hyperresponsiveness in non-asthmatic patients with cedar pollinosis before the Japanese cedar pollen season and during the peak pollen season." | 5.14 | Effects of pranlukast hydrate on airway hyperresponsiveness in non-asthmatic patients with Japanese cedar pollinosis. ( Fukuda, T; Kashima, R; Okada, T; Sagara, H; Yukawa, T, 2009) |
| "We elected to evaluate the effects of repeated dosing with fexofenadine (FEX) and montelukast (ML) at clinically recommended doses in ICS-treated asthmatic patients using adenosine monophosphate (AMP) bronchial challenge as the primary outcome." | 5.11 | Repeated dosing effects of mediator antagonists in inhaled corticosteroid-treated atopic asthmatic patients. ( Haggart, K; Jackson, CM; Lee, DK; Lipworth, BJ, 2004) |
| "Fourteen atopic patients with mild-to-moderate asthma (forced expiratory volume in 1 second of 76%) completed a double-blind, randomized, crossover study consisting of 3-week treatment blocks of either fluticasone propionate-salmeterol, 250 microg twice daily, or fluticasone propionate alone, 250 microg twice daily, in conjunction with either fexofenadine, 180 mg once daily, or matched placebo." | 5.11 | Addition of fexofenadine to inhaled corticosteroid therapy to reduce inflammatory biomarkers in atopic asthma. ( Fardon, TC; Hodge, MR; Lee, DK; Lipworth, BJ, 2005) |
| "Sixteen atopic patients with mild-to-moderate asthma of whom 10 were receiving inhaled corticosteroid therapy (all had positive results to house dust mite on skin prick testing) were randomized in a double-blind, placebo-controlled, cross-over fashion to receive single doses of 5 mg of desloratadine, 180 mg of fexofenadine hydrochloride (FEX), 5 mg of levocetirizine dihydrochloride (LEV), or placebo, with AMP challenge performed 12 hours after dosing." | 5.10 | Comparative in vivo bioactivity of modern H1-antihistamines on AMP challenge in atopic asthma. ( Bates, CE; Currie, GP; Lee, DK; Lipworth, BJ, 2003) |
| "We studied, separately, the effects of the histamine antagonist, fexofenadine hydrochloride, and the leukotriene antagonist, montelukast sodium, and their placebos on airway sensitivity to and recovery from inhaled mannitol in subjects with asthma." | 5.09 | Fexofenadine decreases sensitivity to and montelukast improves recovery from inhaled mannitol. ( Anderson, SD; Brannan, JD; Chan, HK; Gomes, K; King, GG; Seale, JP, 2001) |
| " However, the effect of long-term use of montelukast, a cystenil leukotriene receptor antagonist, on skin prick test hasn't been full elucidated." | 2.78 | The effect of montelukast on wheal reactions in skin prick tests: a double-blind-placebo-controlled randomized trial. ( Aydogan, M; Aydogmus, CY; Bulan, K; Siraneci, R, 2013) |
| " Safety was evaluated through adverse event reporting, electrocardiograms, and pre- and posttreatment laboratory panels and physical examinations." | 2.70 | Safety of fexofenadine in children treated for seasonal allergic rhinitis. ( Bernstein, DI; Goldsobel, A; Graft, DF; Long, J; Meltzer, EO; Portnoy, J, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 12 (92.31) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bulan, K | 1 |
| Aydogan, M | 1 |
| Siraneci, R | 1 |
| Aydogmus, CY | 1 |
| Izumi, N | 1 |
| Mizuguchi, H | 1 |
| Umehara, H | 1 |
| Ogino, S | 1 |
| Fukui, H | 1 |
| Sagara, H | 1 |
| Yukawa, T | 1 |
| Kashima, R | 1 |
| Okada, T | 1 |
| Fukuda, T | 1 |
| Li, AM | 1 |
| Abdullah, VJ | 1 |
| Tsen, CS | 1 |
| Au, CT | 1 |
| Lam, HS | 1 |
| So, HK | 1 |
| Chan, MH | 1 |
| Leung, AW | 1 |
| Chan, IH | 1 |
| Lam, CW | 1 |
| Ng, PC | 1 |
| Shaikh, WA | 1 |
| Shaikh, SW | 1 |
| Lee, DK | 3 |
| Bates, CE | 1 |
| Currie, GP | 1 |
| Lipworth, BJ | 3 |
| Grzelewska-Rzymowska, I | 1 |
| Kroczyńska-Bednarek, J | 1 |
| Pietrzkowicz, M | 1 |
| Jackson, CM | 1 |
| Haggart, K | 1 |
| Fardon, TC | 1 |
| Hodge, MR | 1 |
| Brannan, JD | 1 |
| Anderson, SD | 1 |
| Gomes, K | 1 |
| King, GG | 1 |
| Chan, HK | 1 |
| Seale, JP | 1 |
| Graft, DF | 1 |
| Bernstein, DI | 1 |
| Goldsobel, A | 1 |
| Meltzer, EO | 1 |
| Portnoy, J | 1 |
| Long, J | 1 |
| Wilson, AM | 1 |
1 review available for fexofenadine and Asthma
| Article | Year |
|---|---|
Are antihistamines useful in managing asthma?
Topics: Acetates; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchospirometry; Cetirizine; Cyclopropa | 2002 |
8 trials available for fexofenadine and Asthma
| Article | Year |
|---|---|
The effect of montelukast on wheal reactions in skin prick tests: a double-blind-placebo-controlled randomized trial.
Topics: Acetates; Allergens; Animals; Asthma; Chi-Square Distribution; Child; Cyclopropanes; Dose-Response R | 2013 |
Effects of pranlukast hydrate on airway hyperresponsiveness in non-asthmatic patients with Japanese cedar pollinosis.
Topics: Acetylcholine; Activities of Daily Living; Adult; Anti-Allergic Agents; Anti-Asthmatic Agents; Antig | 2009 |
Leukotriene receptor antagonist in the treatment of childhood allergic rhinitis--a randomized placebo-controlled study.
Topics: Acetates; Adolescent; Asthma; Child; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; | 2009 |
Comparative in vivo bioactivity of modern H1-antihistamines on AMP challenge in atopic asthma.
Topics: Acetates; Adenosine Monophosphate; Adult; Aged; Asthma; Bronchial Provocation Tests; Cetirizine; Cro | 2003 |
Repeated dosing effects of mediator antagonists in inhaled corticosteroid-treated atopic asthmatic patients.
Topics: Acetates; Adenosine Monophosphate; Administration, Inhalation; Adrenal Cortex Hormones; Anti-Allergi | 2004 |
Addition of fexofenadine to inhaled corticosteroid therapy to reduce inflammatory biomarkers in atopic asthma.
Topics: Adenosine Monophosphate; Administration, Inhalation; Adolescent; Adrenal Cortex Hormones; Adult; Alb | 2005 |
Fexofenadine decreases sensitivity to and montelukast improves recovery from inhaled mannitol.
Topics: Acetates; Administration, Inhalation; Adolescent; Adult; Aged; Anti-Asthmatic Agents; Asthma; Bronch | 2001 |
Safety of fexofenadine in children treated for seasonal allergic rhinitis.
Topics: Asthma; Child; Double-Blind Method; Humans; Rhinitis, Allergic, Seasonal; Terfenadine; Therapeutic E | 2001 |
4 other studies available for fexofenadine and Asthma
| Article | Year |
|---|---|
Analysis of disease-dependent sedative profiles of H(1)-antihistamines by large-scale surveillance using the visual analog scale.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Asthma; Butyrophenones; Cetirizine; Child; Chlorpheniram | 2008 |
Allergies in India: a study on medication compliance.
Topics: Adolescent; Adult; Anti-Allergic Agents; Asthma; Bronchodilator Agents; Budesonide; Child; Ethanolam | 2009 |
[Effect of fexofenadine--selective antagonist of histamine receptor (H1) on histamine-induced bronchoconstriction].
Topics: Adult; Anti-Allergic Agents; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Dose-Response | 2003 |
[Hay fever and asthma. Many of your patients have both].
Topics: Asthma; Histamine H1 Antagonists; Humans; Rhinitis, Allergic, Seasonal; Terfenadine; Treatment Outco | 2002 |