fexofenadine has been researched along with Arrhythmias, Cardiac in 8 studies
fexofenadine: a second generation antihistamine; metabolite of the antihistaminic drug terfenadine; structure in first source; RN refers to HCl
fexofenadine : A piperidine-based anti-histamine compound.
Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In order to better understand the variability of pharmacodynamic and pharmacokinetic profiles of terfenadine between the previous studies as well as to qualitatively and quantitatively examine the proarrhythmic potential of its major active metabolite fexofenadine in comparison with that of terfenadine, we directly compared their electropharmacological effects with halothane-anesthetized dogs (n = 3)." | 1.48 | Comparison of electropharmacological effects between terfenadine and its active derivative fexofenadine using a cross-over study in halothane-anesthetized dogs to analyze variability of pharmacodynamic and pharmacokinetic profiles of terfenadine and torsa ( Ando, K; Chiba, K; Goto, A; Hagiwara-Nagasawa, M; Harada, H; Inamura, N; Izumi-Nakaseko, H; Lubna, NJ; Miyamoto, H; Naito, AT; Nakamura, Y; Sugiyama, A; Takagi, K, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ando, K | 1 |
| Nakamura, Y | 1 |
| Hagiwara-Nagasawa, M | 1 |
| Harada, H | 1 |
| Miyamoto, H | 1 |
| Inamura, N | 1 |
| Takagi, K | 1 |
| Goto, A | 1 |
| Chiba, K | 1 |
| Lubna, NJ | 1 |
| Izumi-Nakaseko, H | 1 |
| Naito, AT | 1 |
| Sugiyama, A | 1 |
| Scherer, CR | 1 |
| Lerche, C | 1 |
| Decher, N | 1 |
| Dennis, AT | 1 |
| Maier, P | 1 |
| Ficker, E | 1 |
| Busch, AE | 1 |
| Wollnik, B | 1 |
| Steinmeyer, K | 1 |
| Hove-Madsen, L | 1 |
| Llach, A | 1 |
| Molina, CE | 1 |
| Prat-Vidal, C | 1 |
| Farré, J | 1 |
| Roura, S | 1 |
| Cinca, J | 1 |
| Giraud, T | 1 |
| Po, AL | 1 |
| Kendall, MJ | 1 |
| Kashyap, AS | 1 |
| Kashyap, S | 1 |
| Craig-McFeely, PM | 1 |
| Freemantle, SL | 1 |
| Pearce, GL | 1 |
| Shakir, SA | 1 |
8 other studies available for fexofenadine and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Comparison of electropharmacological effects between terfenadine and its active derivative fexofenadine using a cross-over study in halothane-anesthetized dogs to analyze variability of pharmacodynamic and pharmacokinetic profiles of terfenadine and torsa
Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Blood Pressure; Cross-Over Studies; Dogs; Dose-Response R | 2018 |
The antihistamine fexofenadine does not affect I(Kr) currents in a case report of drug-induced cardiac arrhythmia.
Topics: Aged; Amino Acid Sequence; Amino Acid Substitution; Animals; Arrhythmias, Cardiac; Base Sequence; Bl | 2002 |
The proarrhythmic antihistaminic drug terfenadine increases spontaneous calcium release in human atrial myocytes.
Topics: Arrhythmias, Cardiac; Calcium; Calcium Channels, L-Type; Cyproheptadine; Electrophysiology; Histamin | 2006 |
[Drug side effects and their prevention].
Topics: Arrhythmias, Cardiac; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Ele | 1997 |
QT lengthening and arrhythmias associated with fexofenadine.
Topics: Aged; Arrhythmias, Cardiac; Electrocardiography; Histamine Antagonists; Humans; Risk Factors; Terfen | 1999 |
Causality assessment of adverse drug effects: when is rechallenge ethically acceptable?
Topics: Arrhythmias, Cardiac; Ethics, Medical; Histamine H1 Antagonists; Humans; Terfenadine | 1999 |
Prolonged QTc time and ventricular arrhythmia with fexofenadine.
Topics: Arrhythmias, Cardiac; Heart Conduction System; Histamine H1 Antagonists; Humans; Terfenadine | 1999 |
QT lengthening and life-threatening arrhythmias associated with fexofenadine.
Topics: Arrhythmias, Cardiac; Clinical Trials as Topic; Cohort Studies; Histamine H1 Antagonists; Humans; Te | 2000 |