fevipiprant and Airway-Remodeling

Increased airway smooth muscle mass, a feature of airway remodeling in asthma, is the strongest predictor of airflow limitation and contributes to asthma-associated morbidity and mortality. No current drug therapy for asthma is known to affect airway smooth muscle mass. Although there is increasing evidence that prostaglandin D

Topics: Airway Remodeling; Asthma; Cell Movement; Eosinophilia; Eosinophils; Humans; Indoleacetic Acids; Models, Biological; Muscle, Smooth; Myofibroblasts; Pyridines; Receptors, Immunologic; Receptors, Prostaglandin