ferrous-citrate and Depressive-Disorder--Major

Depressive patients often experience difficulty in performing exercise due to physical and psychological barriers. We examined the effects of 5-aminolevulinic acid (ALA) with sodium ferrous citrate (SFC) supplementation during home-based walking training in middle-aged depressive women. Nine outpatients [53 ± 8 (SD) yr] with major depressive disorder participated in the pilot study with randomized, placebo-controlled, double-blind crossover design. They underwent two trials for 7 days, each performing interval walking training (IWT) with ALA + SFC (ALA + SFC) or placebo supplement intake (PLC) intermittently with >a 10-day washout period. For the first 6 days of each trial, exercise intensity for IWT was measured by accelerometry. Before and after each trial, subjects underwent a graded cycling test, and lactate concentration in plasma ([Lac

Topics: Adult; Aged; Aminolevulinic Acid; Citric Acid; Combined Modality Therapy; Depressive Disorder, Major; Dietary Supplements; Double-Blind Method; Exercise Therapy; Female; Ferrous Compounds; Humans; Levulinic Acids; Middle Aged; Muscle Strength; Oxygen Consumption; Walking