ferrous-citrate and Anemia

Oral iron preparations are useful for the treatment of anemia in hemodialysis patients; however, long-term changes in the iron dynamics and effects of anemia are unknown. Serum ferritin levels and erythropoietin-stimulating agent (ESA)/hemoglobin (Hb) ratios were investigated for 750 days in the following four groups: patients treated with sodium ferrous citrate (SF) (de novo 50 mg/day and 150 mg/day switched from 50 mg/day) and patients treated with 1500 mg/day of ferric citrate (FC) (de novo and switched from 50 mg/day of SF). Compared with the other groups, serum ferritin levels increased less apparently with de novo 50 mg/day SF. ESA/Hb ratios did not change in groups switched from 50 mg/day SF. Conversely, in groups with de novo iron, ESA/Hb ratios decreased and ultimately reached the same levels in all groups. Although more iron results in higher serum ferritin levels, 50 mg/day SF has an equivalent effect for anemia treatment.

Topics: Administration, Oral; Aged; Aged, 80 and over; Anemia; Citric Acid; Female; Ferritins; Ferrous Compounds; Hematinics; Hemoglobins; Humans; Male; Middle Aged; Renal Dialysis; Retrospective Studies; Time Factors

Topics: Administration, Oral; Anemia; Citric Acid; Ferrous Compounds; Humans; Male; Middle Aged; Patch Tests; Photosensitivity Disorders

Topics: Adult; Anemia; Bone Marrow; Citric Acid; Erythropoiesis; Ferrous Compounds; Humans; Iron; Kinetics; Liver; Male; Metabolic Clearance Rate; Radionuclide Imaging; Spleen

Topics: Anemia; Anemia, Hypochromic; Anemia, Iron-Deficiency; Calcium; Calcium Citrate; Citrates; Citric Acid; Drug Therapy; Ferrous Compounds; Iron

Topics: Anemia; Calcium; Calcium Citrate; Citric Acid; Ferrous Compounds; Iron; Pregnancy

Topics: Anemia; Anemia, Hypochromic; Anemia, Iron-Deficiency; Calcium Citrate; Citric Acid; Ferrous Compounds; Iron; Iron, Dietary; Pregnancy; Pregnancy Complications

Topics: Anemia; Calcium; Calcium Citrate; Citric Acid; Female; Ferrous Compounds; Iron; Pregnancy; Pregnancy Complications