ferric nitrilotriacetate has been researched along with Kidney Neoplasms in 65 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (4.62) | 18.7374 |
| 1990's | 25 (38.46) | 18.2507 |
| 2000's | 20 (30.77) | 29.6817 |
| 2010's | 13 (20.00) | 24.3611 |
| 2020's | 4 (6.15) | 2.80 |
| Authors | Studies |
|---|---|
| Akatsuka, S; Cheng, Z; Li, GH; Mori, K; Takahashi, T; Toyokuni, S | 1 |
| El-Sonbaty, S; Haroun, RA; Kandil, EI | 1 |
| Cui, Z; Gao, C; Shi, X; Wang, W; Yang, F; Yang, W | 1 |
| Iqbal, M; Okada, S; Okazaki, Y; Shah, MD; Vun-Sang, S | 1 |
| Akatsuka, S; Chew, SH; Futakuchi, M; Jiang, L; Li, GH; Nakabeppu, Y; Nishiyama, T; Sakamoto, A; Sakumi, K; Suzuki, H; Takahashi, T; Toyokuni, S | 1 |
| Saidullah, B; Siddiqi, A; Sultana, S | 1 |
| Chen, GP; Li, FY; Wang, H; Wang, ZP; Zhao, Y; Zhu, SX | 1 |
| Aguilar-Alonso, FA; Ibarra-Rubio, ME; Pacheco-Bernal, I; Pariente-Pérez, TO; Solano, JD; Vargas-Olvera, CY | 1 |
| Hasan, SK; Nafees, S; Rashid, S; Saidullah, B; Siddiqi, A; Sultana, S | 1 |
| Afzal, SM; Ali, N; Barnwal, P; Hasan, SK; Majed, F; Nafees, S; Rashid, S; Rehman, MU; Siddiqi, A; Sultana, S; Vafa, A | 1 |
| Al-Abbasi, F; Anwar, F; Bhatt, PC; Kaithwas, G; Kumar, V; Rahman, M; Rashid, M; Sethi, N; Singh, Y; Verma, A | 1 |
| Iqbal, M; Mizote, A; Okada, S; Okazaki, Y | 1 |
| Alam, MS; Athar, M; Kaur, G | 1 |
| Akatsuka, S; Jiang, L; Liu, YT; Nagai, H; Nakamura, T; Ohara, H; Okazaki, Y; Toyokuni, S; Yamashita, Y | 1 |
| Aoyama, K; Horiuchi, M; Kato, T; Kawaguchi, H; Komatsu, M; Miyoshi, N; Takeuchi, T; Yoshida, H | 1 |
| Ahmad, ST; Ali, N; Arjumand, W; Nafees, S; Rashid, S; Seth, A; Sultana, S | 1 |
| Aguilar-Alonso, FA; Ibarra-Rubio, ME; Martínez-Martínez, CM; Medina-Campos, ON; Montalvo-Muñoz, F; Sánchez-González, DJ; Solano, JD; Vargas-Olvera, CY | 1 |
| Ali, F; Khan, AQ; Khan, R; Lateef, A; Qamar, W; Rehman, MU; Sultana, S; Tahir, M | 1 |
| Fujisawa, M; Hida, AI; Hosako, M; Kamekawa, M; Mizote, A; Okada, S | 1 |
| Okada, S | 1 |
| Khan, N; Sharma, S; Sultana, S | 1 |
| Khan, N; Sultana, S | 2 |
| Akatsuka, S; Lee, WH; Miyagawa-Hayashino, A; Ozeki, M; Shirase, T; Toyokuni, S; Uchida, K | 1 |
| Jahangir, T; Sultana, S | 1 |
| Akatsuka, S; Dutta, KK; Jiang, L; Kohro, T; Lee, WH; Liu, YT; Noguchi, N; Okawa, K; Onuki, J; Shirase, T; Toyokuni, S; Wada, Y; Watanabe, A; Yamada, Y | 1 |
| Akatsuka, S; Dutta, KK; Jiang, L; Lee, WH; Liu, YT; Masumura, K; Nohmi, T; Onuki, J; Toyokuni, S; Zhong, Y | 1 |
| Iqbal, M; Okada, S; Okazaki, Y | 1 |
| Agarwal, MK; Athar, M; Iqbal, M | 1 |
| Abe, K; Akatsuka, S; Dutta, KK; Izumiya, M; Liu, YT; Mizushima, K; Naito, Y; Nakagama, H; Noguchi, N; Ohara, H; Shang, D; Toyokuni, S; Yoshikawa, T | 1 |
| Jahangir, T; Khan, TH; Prasad, L; Sultana, S | 1 |
| Chang, J; Randerath, E; Randerath, K; Watson, WP; Zhou, GD | 1 |
| Deguchi, J; Kondo, A; Okada, S | 2 |
| Ishikawa, T; Nakatsuru, Y; Oda, H; Qin, X; Yamazaki, Y; Zarkovic, M; Zhang, S | 1 |
| Dizdaroglu, M; Hiai, H; Mori, T; Toyokuni, S | 1 |
| Fukuda, A; Hiai, H; Kawakishi, S; Toyokuni, S; Uchida, K | 1 |
| Liu, M; Okada, S | 1 |
| Dizdaroglu, M; Mori, T; Toyokuni, S | 1 |
| Sagripanti, JL; Toyokuni, S | 1 |
| Deguchi, J; Miyamoto, M; Okada, S | 1 |
| Fukuda, A; Oda, H; Osawa, T; Satoh, K; Toyokuni, S; Uchida, K | 1 |
| Akiyama, T; Hamazaki, S; Okada, S | 1 |
| Fukumoto, M; Hiai, H; Nishiyama, Y; Okamoto, K; Suwa, H; Toyokuni, S | 1 |
| Igarashi, H; Naito, Y; Ohtawara, Y; Shen, Q; Sugimura, H; Tanaka, M; Wang, DY; Xiang, YY | 1 |
| Asami, S; Chung, MH; Hirano, T; Kasai, H; Sugita, A; Yamaguchi, R | 1 |
| Hiai, H; Lehotay, DC; Luo, XP; Tanaka, T; Toyokuni, S; Uchida, K | 1 |
| Fukumoto, M; Hiai, H; Mori, C; Naitoh, H; Nishiyama, Y; Tanaka, T; Toyokuni, S | 1 |
| Hattori, Y; Hiai, H; Nishiyama, Y; Ochi, H; Osawa, T; Tanaka, T; Toyokuni, S; Uchida, K; Yoshida, A | 1 |
| Kasai, H; Okada, S; Yamaguchi, R; Yu, Y; Zhang, D; Zheng, P | 1 |
| Fukuda, A; Hiai, H; Nishiyama, Y; Okada, K; Osawa, T; Satoh, K; Tanaka, T; Toyokuni, S; Uchida, K | 1 |
| Athar, M; Iqbal, M | 1 |
| Hiai, H; Hino, O; Kondo, S; Nishioka, H; Nishiyama, Y; Okada, K; Tanaka, T; Toyokuni, S | 1 |
| Ansar, S; Athar, M; Iqbal, M | 1 |
| Hiai, H; Iwasa, Y; Kondo, S; Tanaka, T; Toyokuni, S | 2 |
| Arai, S; Hanaya, T; Hino, K; Ikeda, M; Kimoto, T; Koya, S; Kurimoto, M; Micallef, MJ; Nomura, Y; Yamamoto, Y | 1 |
| Ichihashi, K; Osawa, T; Toyokuni, S; Uchida, K | 1 |
| Kakehashi, C; Kawabata, T; Mori, M; Okada, S | 1 |
| Oberley, TD | 1 |
| Echizenya, M; Hiai, H; Hiroyasu, M; Kohda, H; Ozeki, M; Tanaka, T; Toyokuni, S | 1 |
| Petrov, AS; Turkevich, EA; Vorob'ev, AV | 1 |
| Awai, M | 1 |
| Ebina, Y; Hamazaki, S; Li, JL; Midorikawa, O; Ogino, F; Okada, S | 1 |
| Ebina, Y; Hamazaki, S; Li, JL; Midorikawa, O; Okada, S | 1 |
65 other study(ies) available for ferric nitrilotriacetate and Kidney Neoplasms
| Article | Year |
|---|---|
Ferroptosis resistance determines high susceptibility of murine A/J strain to iron-induced renal carcinogenesis.
Topics: Animals; Carcinoma, Renal Cell; Cationic Amino Acid Transporter 1; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; Ferric Compounds; Ferritins; Ferroptosis; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Homozygote; Injections, Intraperitoneal; Kidney Neoplasms; Lipid Peroxidation; Lipocalin-2; Male; Mice; Neoplasms, Experimental; Nitrilotriacetic Acid; Oxidative Stress; Receptors, Transferrin; Sequence Deletion; Species Specificity; Up-Regulation | 2022 |
Assessment of the Antitumor Activity of Green Biosynthesized Zinc Nanoparticles as Therapeutic Agent Against Renal Cancer in Rats.
Topics: Animals; Ferric Compounds; Glutathione; Glutathione Peroxidase; Kidney Neoplasms; Lipid Peroxidation; Metal Nanoparticles; Nitrilotriacetic Acid; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Zinc | 2023 |
Pueraria montana (Kudzu vine) Ameliorate the Inflammation and Oxidative Stress against Fe-NTA Induced Renal Cancer.
Topics: Animals; Antioxidants; Biomarkers, Tumor; Body Weight; Creatinine; Cyclooxygenase 2; Diethylnitrosamine; Ferric Compounds; Inflammation; Interleukin-10; Interleukin-1beta; Interleukin-6; Kidney Neoplasms; NF-kappa B; Nitrilotriacetic Acid; Nitrites; Ornithine Decarboxylase; Oxidative Stress; Prostaglandins; Prostaglandins E; Pueraria; Rats; Rats, Wistar; Thymidine; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha; Urea; Uric Acid; Xenobiotics | 2022 |
The therapeutic potential of curcumin in alleviating N-diethylnitrosamine and iron nitrilotriacetate induced renal cell tumours in mice via inhibition of oxidative stress: Implications for cancer chemoprevention.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Blood Urea Nitrogen; Carcinogens; Carcinoma, Renal Cell; Creatinine; Curcumin; Diet; Diethylnitrosamine; Dose-Response Relationship, Drug; Ferric Compounds; Kidney Neoplasms; Male; Mice; Nitrilotriacetic Acid; Oxidative Stress | 2021 |
Fenton reaction-induced renal carcinogenesis in Mutyh-deficient mice exhibits less chromosomal aberrations than the rat model.
Topics: Animals; Chromosome Aberrations; Disease Models, Animal; DNA Glycosylases; Ferric Compounds; Kidney Neoplasms; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitrilotriacetic Acid; Oxidative Stress; Rats; Species Specificity | 2017 |
Anti-carcinogenic effect of hesperidin against renal cell carcinoma by targeting COX-2/PGE2 pathway in Wistar rats.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Carcinogenesis; Carcinoma, Renal Cell; Cell Proliferation; Cyclooxygenase 2; Diethylnitrosamine; Dinoprostone; Ferric Compounds; Hesperidin; Kidney; Kidney Neoplasms; Lipid Peroxidation; Male; Nitrilotriacetic Acid; Oxidative Stress; Plant Extracts; Rats, Wistar | 2018 |
Consumption of hydrogen-rich water protects against ferric nitrilotriacetate-induced nephrotoxicity and early tumor promotional events in rats.
Topics: Animals; Carcinoma, Renal Cell; Ferric Compounds; Hydrogen; Kidney; Kidney Neoplasms; Male; Mitochondria; Nitrilotriacetic Acid; Oxidative Stress; Phosphorylation; Proliferating Cell Nuclear Antigen; Protective Agents; Rats; Rats, Wistar; STAT3 Transcription Factor; Vascular Endothelial Growth Factor A; Water | 2013 |
MAPKs' status at early stages of renal carcinogenesis and tumors induced by ferric nitrilotriacetate.
Topics: Animals; Carcinogenesis; Carcinogens; Carcinoma, Renal Cell; Ferric Compounds; Gene Expression Regulation, Neoplastic; Humans; Kidney Neoplasms; Mitogen-Activated Protein Kinase Kinases; Nitrilotriacetic Acid; Rats | 2015 |
Chemopreventive efficacy of hesperidin against chemically induced nephrotoxicity and renal carcinogenesis via amelioration of oxidative stress and modulation of multiple molecular pathways.
Topics: Animals; Apoptosis; Carcinogenesis; Carcinogens; Carcinoma, Renal Cell; Cell Proliferation; Disease Models, Animal; Ferric Compounds; Hesperidin; Immunohistochemistry; Kidney Neoplasms; Male; Nitrilotriacetic Acid; Oxidative Stress; Rats; Rats, Wistar; Signal Transduction | 2015 |
Inhibition of precancerous lesions development in kidneys by chrysin via regulating hyperproliferation, inflammation and apoptosis at pre clinical stage.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Apoptosis; Carcinogenesis; Cell Proliferation; Ferric Compounds; Flavonoids; Gene Expression Regulation, Neoplastic; Inflammation; Kidney; Kidney Neoplasms; Lipid Peroxidation; Male; Nitrilotriacetic Acid; Oxidative Stress; Precancerous Conditions; Rats; Rats, Wistar; Up-Regulation | 2016 |
Chemomodulatory effect Melastoma Malabathricum Linn against chemically induced renal carcinogenesis rats via attenuation of inflammation, oxidative stress, and early markers of tumor expansion.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biomarkers, Tumor; Ferric Compounds; Inflammation; Inflammation Mediators; Kidney Neoplasms; Male; Melastomataceae; Nitrilotriacetic Acid; Oxidative Stress; Plant Extracts; Random Allocation; Rats; Rats, Wistar; Treatment Outcome; Tumor Burden | 2016 |
Antioxidant biofactor, a processed grain food, inhibits iron nitrilotriacetate-induced renal tumorigenesis, hyperproliferative response, and oxidative damage.
Topics: Animals; Cell Proliferation; Dose-Response Relationship, Drug; Ferric Compounds; Glutathione; Kidney Neoplasms; Lipid Peroxidation; Male; Nitrilotriacetic Acid; Ornithine Decarboxylase Inhibitors; Oxidation-Reduction; Phenols; Plant Extracts; Rats; Rats, Wistar | 2008 |
Dietary supplementation of silymarin protects against chemically induced nephrotoxicity, inflammation and renal tumor promotion response.
Topics: Aldehydes; Animals; Antioxidants; Cyclooxygenase 2; Cytokines; Dietary Supplements; DNA, Neoplasm; Female; Ferric Compounds; Inflammation; Inflammation Mediators; Kidney; Kidney Neoplasms; Lipid Peroxidation; Metabolic Detoxication, Phase II; Metallothionein; Mice; NF-kappa B; Nitric Oxide Synthase Type II; Nitrilotriacetic Acid; Ornithine Decarboxylase; Protective Agents; Silymarin; Treatment Outcome | 2010 |
Stage-specific roles of fibulin-5 during oxidative stress-induced renal carcinogenesis in rats.
Topics: Animals; Base Sequence; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; Extracellular Matrix Proteins; Ferric Compounds; Gene Expression Regulation, Neoplastic; Genome-Wide Association Study; Immunohistochemistry; Kidney Neoplasms; Kidney Tubules, Proximal; Loss of Heterozygosity; Lung Neoplasms; Male; Microsatellite Repeats; Molecular Sequence Data; Nitrilotriacetic Acid; Oligonucleotide Array Sequence Analysis; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar; Recombinant Proteins; Signal Transduction | 2011 |
Effect of habitual exercise on renal carcinogenesis by ferric nitrilotriacetate.
Topics: Animals; Carcinogens; Carcinoma, Renal Cell; Ferric Compounds; Kidney; Kidney Neoplasms; Male; Nitrilotriacetic Acid; Physical Conditioning, Animal; Rats; Rats, Inbred F344 | 2011 |
Preclinical renal cancer chemopreventive efficacy of geraniol by modulation of multiple molecular pathways.
Topics: Acyclic Monoterpenes; Animals; Antineoplastic Agents; Drug Evaluation, Preclinical; Ferric Compounds; Kidney Neoplasms; Male; Nitrilotriacetic Acid; Rats; Rats, Wistar; Signal Transduction; Terpenes; Treatment Outcome | 2011 |
Characterization of N-diethylnitrosamine-initiated and ferric nitrilotriacetate-promoted renal cell carcinoma experimental model and effect of a tamarind seed extract against acute nephrotoxicity and carcinogenesis.
Topics: Animals; Carcinogens; Carcinoma, Renal Cell; Cell Transformation, Neoplastic; Diethylnitrosamine; Disease Models, Animal; Ferric Compounds; Humans; Kidney Neoplasms; Neoplasms, Experimental; Nitrilotriacetic Acid; Oxidative Stress; Plant Extracts; Rats; Rats, Wistar; Seeds; Tamarindus | 2012 |
Chrysin suppresses renal carcinogenesis via amelioration of hyperproliferation, oxidative stress and inflammation: plausible role of NF-κB.
Topics: Animals; Carcinogens; Carcinoma, Renal Cell; Cell Proliferation; Cyclooxygenase 2; Cytokines; Diethylnitrosamine; Ferric Compounds; Flavonoids; Kidney Neoplasms; Male; NF-kappa B; Nitric Oxide Synthase Type II; Nitrilotriacetic Acid; Ornithine Decarboxylase; Oxidative Stress; Pilot Projects; Proliferating Cell Nuclear Antigen; Random Allocation; Rats; Rats, Wistar | 2013 |
Effects of phlebotomy on the growth of ferric nitrilotriacetate-induced renal cell carcinoma.
Topics: Animals; Carcinogens; Carcinoma, Renal Cell; Ferric Compounds; Incidence; Iron; Kidney Neoplasms; Male; Nitrilotriacetic Acid; Phlebotomy; Rats; Rats, Wistar | 2002 |
Prevention of free-radical mediated tissue damage and carcinogenesis induced by low-molecular-weight iron.
Topics: Animals; Carcinogens; Carcinoma, Renal Cell; Ferric Compounds; Free Radicals; Iron; Kidney; Kidney Neoplasms; Neoplasms; Nitrilotriacetic Acid; Phlebotomy; Rats; Rats, Wistar | 2003 |
Amelioration of ferric nitrilotriacetate (Fe-NTA) induced renal oxidative stress and tumor promotion response by coumarin (1,2-benzopyrone) in Wistar rats.
Topics: Animals; Antineoplastic Agents; Antioxidants; Blood Urea Nitrogen; Carcinogens; Coumarins; Creatinine; DNA; Female; Ferric Compounds; gamma-Glutamyltransferase; Glutathione; Hydrogen Peroxide; Kidney; Kidney Neoplasms; Lipid Peroxidation; Nitrilotriacetic Acid; Ornithine Decarboxylase; Oxidative Stress; Rats; Rats, Wistar; Thymidine; Xanthine Oxidase | 2004 |
Inhibition of two stage renal carcinogenesis, oxidative damage and hyperproliferative response by Nigella sativa.
Topics: Animals; Carcinogens; Carcinoma, Renal Cell; Cell Proliferation; Chemoprevention; Female; Ferric Compounds; Kidney Neoplasms; Nigella sativa; Nitrilotriacetic Acid; Oxidative Stress; Plant Extracts; Rats; Rats, Wistar | 2005 |
Anticarcinogenic effect of Nymphaea alba against oxidative damage, hyperproliferative response and renal carcinogenesis in Wistar rats.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Blood Urea Nitrogen; Cell Proliferation; Creatinine; DNA; DNA Damage; Enzymes; Ferric Compounds; Kidney; Kidney Neoplasms; Lipid Peroxidation; Male; Nitrilotriacetic Acid; Nymphaea; Ornithine Decarboxylase; Oxidative Stress; Plant Extracts; Rats; Rats, Wistar | 2005 |
Susceptibility of actin to modification by 4-hydroxy-2-nonenal.
Topics: Actins; Albumins; Aldehydes; Animals; Antibodies, Monoclonal; Blotting, Western; Cysteine; Ferric Compounds; Glyceraldehyde-3-Phosphate Dehydrogenases; Hemocyanins; Histidine; Kidney; Kidney Neoplasms; Lysine; Male; Metallothionein; Nitrilotriacetic Acid; Rats; Rats, Wistar; Specific Pathogen-Free Organisms; Superoxide Dismutase | 2005 |
Modulatory effects of Pluchea lanceolata against chemically induced oxidative damage, hyperproliferation and two-stage renal carcinogenesis in Wistar rats.
Topics: Animals; Asteraceae; Catalase; Cell Proliferation; Ferric Compounds; Flavonols; Glucosephosphate Dehydrogenase; Glutathione; Glutathione Peroxidase; Hydrogen Peroxide; Kidney Neoplasms; Lipid Peroxidation; Male; Neoplasm Staging; Nitrilotriacetic Acid; Ornithine Decarboxylase; Oxidative Stress; Phytotherapy; Plant Extracts; Quinone Reductases; Rats; Rats, Wistar; Xanthine Oxidase | 2006 |
Alpha-tocopherol induces calnexin in renal tubular cells: another protective mechanism against free radical-induced cellular damage.
Topics: alpha-Tocopherol; Animals; Calnexin; Carcinogens; Cells, Cultured; Cytoprotection; Dose-Response Relationship, Drug; Ferric Compounds; Free Radicals; Kidney Neoplasms; Kidney Tubules; Male; Nitrilotriacetic Acid; Oxidative Stress; Precancerous Conditions; Rats; Rats, Wistar | 2006 |
Deletion and single nucleotide substitution at G:C in the kidney of gpt delta transgenic mice after ferric nitrilotriacetate treatment.
Topics: Animals; Base Sequence; Carcinogens; DNA Damage; DNA Mutational Analysis; Escherichia coli Proteins; Ferric Compounds; Immunoprecipitation; Kidney; Kidney Neoplasms; Mice; Mice, Inbred C57BL; Mice, Transgenic; Molecular Sequence Data; Mutation; Nitrilotriacetic Acid; Pentosyltransferases; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Sequence Deletion | 2006 |
Probucol modulates iron nitrilotriacetate (Fe-NTA)-dependent renal carcinogenesis and hyperproliferative response: diminution of oxidative stress.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Carcinogens; Cell Proliferation; Drug Evaluation, Preclinical; Ferric Compounds; Kidney Neoplasms; Male; Mice; Mice, Inbred Strains; Nitrilotriacetic Acid; Oxidative Stress; Probucol | 2007 |
Garlic oil ameliorates ferric nitrilotriacetate (Fe-NTA)-induced damage and tumor promotion: implications for cancer prevention.
Topics: Administration, Oral; Allyl Compounds; Animals; Anticarcinogenic Agents; Carcinogens; DNA; Dose-Response Relationship, Drug; Ferric Compounds; Kidney; Kidney Neoplasms; Lipid Peroxidation; Male; Nitrilotriacetic Acid; Random Allocation; Rats; Rats, Wistar; Sulfides | 2007 |
Chronic oxidative stress causes amplification and overexpression of ptprz1 protein tyrosine phosphatase to activate beta-catenin pathway.
Topics: Animals; beta Catenin; Carcinogens; Carcinoma, Renal Cell; Ferric Compounds; Gene Amplification; Gene Expression Profiling; Kidney Neoplasms; Neoplasm Staging; Nitrilotriacetic Acid; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Rats; Receptor-Like Protein Tyrosine Phosphatases, Class 5 | 2007 |
Abrogation of DEN/Fe-NTA induced carcinogenic response, oxidative damage and subsequent cell proliferation response by Terminalia chebula in kidney of Wistar rats.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Carcinogens; Cell Proliferation; Chelating Agents; DNA; Ferric Compounds; Glutathione; Kidney; Kidney Diseases; Kidney Function Tests; Kidney Neoplasms; Lipid Peroxidation; Male; Microsomes; Nitrilotriacetic Acid; Oxidative Stress; Plant Extracts; Quinone Reductases; Rats; Rats, Wistar; Terminalia; Xanthine Oxidase | 2007 |
Intensification and depletion of specific bulky renal DNA adducts (I-compounds) following exposure of male F344 rats to the renal carcinogen ferric nitrilotriacetate (Fe-NTA).
Topics: Age Factors; Animals; Carcinogens; DNA Adducts; Ferric Compounds; Kidney; Kidney Neoplasms; Liver; Lung; Male; Nitrilotriacetic Acid; Oxidation-Reduction; Rats; Rats, Inbred Strains; Time Factors | 1995 |
Renal cysts and associated renal tumours in male ddY mice injected with ferric nitrilotriacetate.
Topics: Animals; Carcinogens; Cysts; Disease Susceptibility; Ferric Compounds; Kidney Diseases; Kidney Neoplasms; Male; Mice; Nitrilotriacetic Acid; Precancerous Conditions | 1995 |
Inhibitory effect of probucol on nephrotoxicity induced by ferric nitrilotriacetate (Fe-NTA) in rats.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Diet; Ferric Compounds; Kidney; Kidney Cortex; Kidney Neoplasms; Male; Nitrilotriacetic Acid; Probucol; Rats; Rats, Wistar | 1995 |
Treatment of Wistar rats with a renal carcinogen, ferric nitrilotriacetate, causes DNA-protein cross-linking between thymine and tyrosine in their renal chromatin.
Topics: Adenocarcinoma; Animals; Carcinogens; Chromatin; Cross-Linking Reagents; DNA Damage; DNA, Neoplasm; Ferric Compounds; Kidney; Kidney Neoplasms; Kidney Tubules, Proximal; Male; Neoplasm Proteins; Nitrilotriacetic Acid; Rats; Rats, Wistar; Thymine; Tyrosine | 1995 |
A renal carcinogen ferric nitrilotriacetate mediates a temporary accumulation of aldehyde-modified proteins within cytosolic compartment of rat kidney.
Topics: Adenocarcinoma; Aldehydes; Animals; Carcinogens; Cytosol; Ferric Compounds; Immunoblotting; Immunohistochemistry; Kidney; Kidney Neoplasms; Lipid Peroxidation; Male; Malondialdehyde; Nitrilotriacetic Acid; Phenylhydrazines; Proteins; Rats; Rats, Wistar; Subcellular Fractions; Thiobarbituric Acid Reactive Substances | 1995 |
Induction of free radicals and tumors in the kidneys of Wistar rats by ferric ethylenediamine-N,N'-diacetate.
Topics: Adenocarcinoma; Adenoma; Animals; Catalase; Cell Transformation, Neoplastic; Deoxyribose; Edetic Acid; Ferric Compounds; Formates; Hydrogen Peroxide; Hydroxyl Radical; Kidney; Kidney Neoplasms; Lipid Peroxidation; Male; Mannitol; Nitrilotriacetic Acid; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase; Superoxides; Thiobarbituric Acid Reactive Substances; Thiourea | 1994 |
DNA base modifications in renal chromatin of Wistar rats treated with a renal carcinogen, ferric nitrilotriacetate.
Topics: Animals; Base Sequence; Carcinogens; Chromatin; DNA; DNA Damage; Ferric Compounds; Gas Chromatography-Mass Spectrometry; Hydroxyl Radical; Kidney; Kidney Neoplasms; Kidney Tubules, Proximal; Male; Nitrilotriacetic Acid; Purines; Pyrimidines; Rats; Rats, Wistar | 1994 |
DNA single- and double-strand breaks produced by ferric nitrilotriacetate in relation to renal tubular carcinogenesis.
Topics: Adenocarcinoma; DNA; DNA Damage; DNA, Circular; DNA, Single-Stranded; DNA, Superhelical; Ferric Compounds; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kidney Neoplasms; Kidney Tubules, Proximal; Kinetics; Nitrilotriacetic Acid; Plasmids | 1993 |
Sex hormone-dependent renal cell carcinogenesis induced by ferric nitrilotriacetate in Wistar rats.
Topics: Animals; Carcinogens; Carcinoma, Renal Cell; Disease Susceptibility; Estradiol; Female; Ferric Compounds; Kidney; Kidney Neoplasms; Lipid Peroxidation; Male; Neoplasms, Hormone-Dependent; Nitrilotriacetic Acid; Orchiectomy; Ovariectomy; Rats; Rats, Wistar; Sex Characteristics; Testosterone | 1995 |
Oxidative stress response in iron-induced renal carcinogenesis: acute nephrotoxicity mediates the enhanced expression of glutathione S-transferase Yp isozyme.
Topics: Adenocarcinoma; Animals; Carcinogens; Ferric Compounds; Free Radicals; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glutathione Transferase; Iron Chelating Agents; Isoenzymes; Kidney; Kidney Neoplasms; Male; Nitrilotriacetic Acid; Oxidative Stress; Rats; Rats, Wistar | 1996 |
Absence of ras mutations and low incidence of p53 mutations in renal cell carcinomas induced by ferric nitrilotriacetate.
Topics: Animals; Base Sequence; Carcinogens; Carcinoma, Renal Cell; Cell Transformation, Neoplastic; Codon; DNA Mutational Analysis; Exons; Ferric Compounds; Genes, p53; Genes, ras; Kidney Neoplasms; Male; Molecular Sequence Data; Nitrilotriacetic Acid; Polymerase Chain Reaction; Rats; Rats, Wistar | 1995 |
Low incidence of point mutations in H-, K- and N-ras oncogenes and p53 tumor suppressor gene in renal cell carcinoma and peritoneal mesothelioma of Wistar rats induced by ferric nitrilotriacetate.
Topics: Animals; Base Sequence; Carcinogens; Carcinoma, Renal Cell; DNA Damage; Ferric Compounds; Free Radicals; Genes, p53; Genes, ras; Kidney Neoplasms; Male; Mesothelioma; Molecular Sequence Data; Nitrilotriacetic Acid; Peritoneal Neoplasms; Point Mutation; Polymorphism, Single-Stranded Conformational; Rats; Rats, Wistar; Specific Pathogen-Free Organisms | 1995 |
Expression of structure-specific recognition protein mRNA in fetal kidney and Fe-nitrilotriacetate-induced renal carcinoma in the rat.
Topics: Animals; Carcinogens; DNA, Complementary; Female; Ferric Compounds; Fetus; High Mobility Group Proteins; Humans; In Situ Hybridization; Kidney; Kidney Neoplasms; Nitrilotriacetic Acid; Pregnancy; Rats; RNA, Messenger; Tumor Cells, Cultured | 1996 |
Increased 8-hydroxyguanine levels in DNA and its repair activity in rat kidney after administration of a renal carcinogen, ferric nitrilotriacetate.
Topics: Animals; Carcinogens; DNA; DNA Damage; DNA Repair; Ferric Compounds; Guanine; Kidney; Kidney Neoplasms; Male; Nitrilotriacetic Acid; Oxidative Stress; Rats; Rats, Wistar | 1996 |
Induction of a wide range of C(2-12) aldehydes and C(7-12) acyloins in the kidney of Wistar rats after treatment with a renal carcinogen, ferric nitrilotriacetate.
Topics: Aldehydes; Animals; Carcinogens; Carcinoma, Renal Cell; Chromatography, Gas; Fatty Alcohols; Ferric Compounds; Immunohistochemistry; Kidney; Kidney Neoplasms; Kinetics; Liver; Male; Malondialdehyde; Nitrilotriacetic Acid; Rats; Rats, Wistar | 1997 |
Overexpression of integrin-associated protein (CD47) in rat kidney treated with a renal carcinogen, ferric nitrilotriacetate.
Topics: Amino Acid Sequence; Animals; Antigens, CD; Base Sequence; Blotting, Northern; Carcinogens; Carcinoma, Renal Cell; Carrier Proteins; CD47 Antigen; DNA, Complementary; Ferric Compounds; Humans; Kidney; Kidney Neoplasms; Kidney Tubules; Male; Mice; Molecular Sequence Data; Nitrilotriacetic Acid; Rats; Rats, Wistar; Specific Pathogen-Free Organisms | 1997 |
Quantitative immunohistochemical determination of 8-hydroxy-2'-deoxyguanosine by a monoclonal antibody N45.1: its application to ferric nitrilotriacetate-induced renal carcinogenesis model.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antibodies, Monoclonal; Antibody Specificity; Carcinogens; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA Damage; Ferric Compounds; Immunohistochemistry; Kidney; Kidney Neoplasms; Male; Models, Biological; Nitrilotriacetic Acid; Oxidative Stress; Rats; Rats, Wistar | 1997 |
Vitamin E inhibits apoptosis, DNA modification, and cancer incidence induced by iron-mediated peroxidation in Wistar rat kidney.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Apoptosis; Body Weight; Carcinogens; Deoxyguanosine; Disease Models, Animal; DNA; Ferric Compounds; Kidney; Kidney Neoplasms; Lipid Peroxidation; Male; Nitrilotriacetic Acid; Rats; Rats, Wistar; Time Factors; Vitamin E | 1997 |
Over-expression of glutathione S-transferase Yp isozyme and concomitant down-regulation of Ya isozyme in renal cell carcinoma of rats induced by ferric nitrilotriacetate.
Topics: Animals; Blotting, Western; Carcinogens; Carcinoma, Renal Cell; Down-Regulation; Ferric Compounds; Glutathione Transferase; Immunohistochemistry; Isoenzymes; Kidney Neoplasms; Male; Nitrilotriacetic Acid; Rats; Rats, Wistar | 1998 |
Ferric nitrilotriacetate promotes N-diethylnitrosamine-induced renal tumorigenesis in the rat: implications for the involvement of oxidative stress.
Topics: Adenocarcinoma; Animals; Antioxidants; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Carcinogens; Diethylnitrosamine; Drug Synergism; Ferric Compounds; Kidney; Kidney Neoplasms; Lipid Peroxidation; Male; Nitrilotriacetic Acid; Ornithine Decarboxylase; Oxidative Stress; Rats; Rats, Wistar | 1998 |
Development of high-grade renal cell carcinomas in rats independently of somatic mutations in the Tsc2 and VHL tumor suppressor genes.
Topics: Animals; Base Sequence; Carcinogens; Carcinoma, Renal Cell; Exons; Female; Ferric Compounds; Genes, Tumor Suppressor; Kidney Neoplasms; Male; Molecular Sequence Data; Mutagens; Mutation; Nitrilotriacetic Acid; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Rats; Rats, Wistar; Repressor Proteins; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins; von Hippel-Lindau Disease | 1998 |
Intranuclear iron deposition in hepatocytes and renal tubular cells in mice treated with ferric nitrilotriacetate.
Topics: Animals; Cell Nucleus; Cytoplasm; Female; Ferric Compounds; Iron; Kidney Neoplasms; Kidney Tubules; Liver; Male; Mice; Microscopy, Electron; Nitrilotriacetic Acid; Random Allocation; Sex Factors | 1998 |
Nordihydroguairetic acid is a potent inhibitor of ferric-nitrilotriacetate-mediated hepatic and renal toxicity, and renal tumour promotion, in mice.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Blood Urea Nitrogen; Carcinogens; Catalase; Creatinine; Diethylnitrosamine; DNA Replication; Ferric Compounds; gamma-Glutamyltransferase; Glucosephosphate Dehydrogenase; Glutathione; Glutathione Reductase; Glutathione Transferase; Hydrogen Peroxide; Kidney; Kidney Neoplasms; Lipid Peroxidation; Liver; Male; Masoprocol; Mice; Nitrilotriacetic Acid; Ornithine Decarboxylase; Oxidation-Reduction; Oxidative Stress | 1999 |
High incidence of allelic loss on chromosome 5 and inactivation of p15INK4B and p16INK4A tumor suppressor genes in oxystress-induced renal cell carcinoma of rats.
Topics: Animals; Base Sequence; Blotting, Southern; Carcinogens; Carcinoma, Renal Cell; Carrier Proteins; Cell Cycle Proteins; Chromosomes, Human, Pair 5; CpG Islands; Crosses, Genetic; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; DNA Methylation; DNA, Neoplasm; Ferric Compounds; Gene Deletion; Genes, p16; Genes, Tumor Suppressor; Humans; Kidney Neoplasms; Kidney Tubules, Proximal; Loss of Heterozygosity; Microsatellite Repeats; Molecular Sequence Data; Nitrilotriacetic Acid; Oxidative Stress; Point Mutation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Rats; Rats, Wistar; Tumor Suppressor Proteins | 1999 |
Expression of stress-response and cell proliferation genes in renal cell carcinoma induced by oxidative stress.
Topics: Animals; Base Sequence; Blotting, Northern; Carcinogens; Carcinoma, Renal Cell; Cell Division; Ferric Compounds; Gene Expression; Kidney Neoplasms; Molecular Sequence Data; Nitrilotriacetic Acid; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Rats; Rats, Wistar; Tumor Cells, Cultured | 2000 |
Renal carcinogenesis induced by ferric nitrilotriacetate in mice, and protection from it by Brazilian propolis and artepillin C.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Antineoplastic Agents; Carcinoma, Renal Cell; Deoxyguanosine; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Female; Ferric Compounds; Fluorescent Antibody Technique, Indirect; Kidney; Kidney Neoplasms; Lipid Peroxidation; Male; Mice; Mutagens; Nitrilotriacetic Acid; Phenylpropionates; Propolis; Thiobarbituric Acid Reactive Substances | 2000 |
Endogenous formation of protein adducts with carcinogenic aldehydes: implications for oxidative stress.
Topics: Aldehydes; Animals; Antibodies, Monoclonal; Carcinogens; Ferric Compounds; Histidine; Kidney Neoplasms; Kidney Tubules, Proximal; Lipid Peroxidation; Lysine; Male; Models, Chemical; Nitrilotriacetic Acid; Oxidative Stress; Rats; Rats, Wistar; Serum Albumin, Bovine | 2001 |
In vitro transformation of rat renal cells by treatment with ferric nitrilotriacetate.
Topics: Animals; Carcinogens; Cell Survival; Cell Transformation, Neoplastic; Ferric Compounds; Humans; Kidney; Kidney Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Nitrilotriacetic Acid; Rats; Tumor Cells, Cultured | 2001 |
Oxidative damage and cancer.
Topics: Animals; Antioxidants; Carcinogens; Disease Models, Animal; Ferric Compounds; Free Radical Scavengers; Gene Silencing; Humans; Kidney Neoplasms; Neoplasms; Nitrilotriacetic Acid; Oxidation-Reduction; Reactive Oxygen Species; Skin Neoplasms; Superoxide Dismutase | 2002 |
Specific allelic loss of p16 (INK4A) tumor suppressor gene after weeks of iron-mediated oxidative damage during rat renal carcinogenesis.
Topics: Animals; Carcinogens; Cyclin-Dependent Kinase Inhibitor p16; Ferric Compounds; Genes, Tumor Suppressor; Humans; In Situ Hybridization, Fluorescence; Iron; Kidney Neoplasms; Male; Nitrilotriacetic Acid; Oxidation-Reduction; Rats; Rats, Wistar | 2002 |
[The morphology of kidney tumors induced in rats by iron nitrilotriacetate].
Topics: Animals; Carcinogens; Carcinoma; Disease Models, Animal; Ferric Compounds; Kidney; Kidney Neoplasms; Male; Nitrilotriacetic Acid; Rats | 1992 |
[Ferric nitrilotriacetate (Fe3+-NTA) produces active oxygens and induces malignant transformation on cultured rat liver cells].
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Ferric Compounds; Free Radicals; Kidney Neoplasms; Lipid Peroxidation; Liver; Liver Neoplasms, Experimental; Male; Nitrilotriacetic Acid; Rats; Rats, Inbred Strains; Superoxides | 1988 |
Nephrotoxicity and renal cell carcinoma after use of iron- and aluminum-nitrilotriacetate complexes in rats.
Topics: Acetates; Aluminum; Animals; Carcinoma, Renal Cell; Ferric Compounds; Iron; Kidney; Kidney Neoplasms; Male; Nitrilotriacetic Acid; Rats; Rats, Inbred Strains | 1986 |
Subacute nephrotoxicity and induction of renal cell carcinoma in mice treated with ferric nitrilotriacetate.
Topics: Animals; Carcinogens; Carcinoma, Renal Cell; Female; Ferric Compounds; Kidney; Kidney Neoplasms; Male; Mice; Mice, Inbred A; Nitrilotriacetic Acid; Sex Factors | 1987 |