ferric chloride has been researched along with Disease Models, Animal in 168 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.60) | 18.7374 |
| 1990's | 9 (5.36) | 18.2507 |
| 2000's | 50 (29.76) | 29.6817 |
| 2010's | 103 (61.31) | 24.3611 |
| 2020's | 5 (2.98) | 2.80 |
| Authors | Studies |
|---|---|
| Abdelfadiel, EI; Afosah, DK; Al-Horani, RA; Brophy, DF; Desai, UR; Martin, EJ; Mohammed, B; Morla, S; Sakagami, M; Sistla, JC | 1 |
| Grover, SP; Mackman, N | 1 |
| Brill, A; Campos, J | 1 |
| Alamri, FF; Arumugam, TV; Jayaraman, S; Karamyan, ST; Karamyan, VT; Lee, P; Syeara, N | 1 |
| Cosemans, J; Hechler, B; Karel, M; Kuijpers, M | 1 |
| Abdelhafez, MM; Angelillo-Scherrer, A; Cook, KE; Cooke, A; Demarest, CT; Deyle, K; Gonschorek, P; Heinis, C; Kong, XD; Lamers, C; Middendorp, SJ; Prince, R; Rieben, R; Roberts, K; Umei, N; Wilbs, J | 1 |
| Bem, D; Byrne, M; Lordkipanidzé, M; Mazharian, A; Meyaard, L; Patel, P; Raslan, Z; Senis, YA; Smith, CW; Thomas, SG; Watson, SP | 1 |
| Ali, C; Denis, CV; Diamond, SL; Gakuba, C; Gauberti, M; Herbig, BA; Lenting, PJ; Martinez de Lizarrondo, S; Repessé, Y; Touzé, E; Vivien, D | 1 |
| Chang, CH; Chung, CH; Hsu, CC; Huang, TF; Peng, HC; Tsai, CC; Tseng, YJ; Tu, YS | 1 |
| Chang, L; Ding, Z; Hu, L; Kunapuli, SP; Luo, X; Qi, Z; Wang, Y; Yan, H; Yan, Y; Ye, H; Zhai, L; Zhang, S; Zhang, Y | 1 |
| Andreakos, E; Angelidou, I; Arampatzioglou, A; Arelaki, S; Bochenek, M; Chrysanthopoulou, A; Couladouros, EA; Galani, IE; Kambas, K; Konstantinides, S; Mitroulis, I; Mitsios, A; Ritis, K; Schäfer, K; Skendros, P; Stakos, D; Vidali, V | 1 |
| Fan, Q; Fu, C; Li, B; Ma, G; Yao, Y | 1 |
| Adler, K; Borst, O; Brandl, R; Degen, H; Fassbender, J; Gawaz, M; Göbel, S; Jamasbi, J; Lorenz, R; Mojica Munoz, AK; Münch, G; Siess, W; Ungerer, M; Walker, B; Ziegler, M | 1 |
| Chen, CH; Fu, WM; Gau, SS; Hsu, CC; Huang, SW; Huang, TF; Liao, HM; Liou, HC; Lu, DH; Tu, HJ | 1 |
| Cai, Y; Chen, X; Hu, H; Hu, M; Hu, X; Ke, Y; Liu, Y; Luo, D; Wang, S; Wang, Y; Yang, Z; Yue, M; Zhou, Y | 1 |
| Ci, H; Ge, X; Song, W; Tian, G; Zhang, Y | 1 |
| Deng, X; Guo, XB; Sheng, G; Wei, Y | 1 |
| Chandraratne, S; Ehrlich, A; Hoti, Q; Konrad, I; Legate, KR; Lorenz, M; Massberg, S; Novotny, J; Oberdieck, P; Pelisek, J; Philippi, V; Pircher, J; Schubert, I; Schulz, C; Stark, K; Titova, A; Urtz, N; von Brühl, ML; Weinberger, T | 1 |
| Ding, Y; Krafft, P; Li, Q; Wan, W; Wu, G; Yan, F; Zhan, Q; Zhang, JH; Zhang, Y | 1 |
| Bochenek, ML; Gogiraju, R; Hubert, A; Jäger, M; Münzel, T; Schäfer, K | 1 |
| Bhakta, V; Eltringham-Smith, LJ; Sheffield, WP | 1 |
| Han, M; Han, N; Liu, Z; Lv, G; Song, Z; Yin, J; Yu, B; Zhou, J | 1 |
| Liu, X; Lu, D; Ma, T; Meng, Q; Shen, Z; Sun, J; Yang, J; Yang, Z; Zhang, J; Zhang, Z | 1 |
| Bratton, C; Dornbos, D; Gnyawali, S; Huttinger, AL; Jones, C; Joseph, ME; Layzer, JM; Musgrave, NJ; Nimjee, SM; Sen, C; Sullenger, BA; Talentino, S; Venetos, N; Wheeler, DG | 1 |
| Cooley, B; Diaz, JA; Grover, SP; Henke, PK; Lal, BK; Mackman, N; Palmer, OR; Saha, P; Smith, A; Wakefield, TW | 1 |
| Ganson, NJ; Hershfield, MS; Layzer, JM; Moreno, A; Pitoc, GA; Sullenger, BA; Tarantal, AF | 1 |
| Anisimova, VA; Divaeva, LN; Kucheryavenko, AF; Kuz'menko, TA; Morkovnik, AS; Sirotenko, VS; Spasov, AA | 1 |
| Aleman, MM; Byrnes, JR; Cooley, BC; Heisler, MJ; Machlus, KR; Walton, BL; Wang, JG; Wolberg, AS | 1 |
| Assumpção, TC; Francischetti, IM; Kotsyfakis, M; Li, Y; Ma, D; Mizurini, DM; Monteiro, RQ; Qi, Y; Ribeiro, JM | 1 |
| Dai, X; Hou, Y; Lei, X; Li, BX; Liang, C; Marshall, AH; Ni, H; Reheman, A; Vanhoorelbeke, K; Wang, Y; Zhou, H | 1 |
| Gupta, N; Li, W; McIntyre, TM; Silverstein, RL; Willard, B | 1 |
| Borst, O; Chatterjee, M; Cosemans, JM; Elvers, M; Feijge, MA; Ferlinz, K; Gawaz, M; Gulbins, E; Heemskerk, JW; Lang, F; Leibrock, C; May, AE; Münzer, P; Schaller, M; Schmid, E; Schmidt, EM; Schmidt, S; Seizer, P; Towhid, ST; Walker, B | 1 |
| Darbousset, R; Dignat-George, F; Dubois, C; Mezouar, S; Panicot-Dubois, L | 1 |
| Jackson, DE; Linden, MD; Mosawy, S; Woodman, OL | 1 |
| Fett, A; Stolz, E; Wessels, C | 1 |
| Bialkowska, K; Byzova, TV; Chen, X; Gao, J; Liu, J; Ma, YQ; Plow, EF; Pluskota, E; White, GC; Xu, Z; Zhi, H | 1 |
| Brown, C; Crawford, B; Danisment, O; Hegadorn, CA; Lillicrap, D; Mewburn, J; Nieswandt, B; Pruss, CM; Rydz, N; Shida, Y; Sponagle, K; Stegner, D; Vidal, B | 1 |
| Li, W; McIntyre, TM; Silverstein, RL | 1 |
| Díez-Municio, M; Herrero, M; Laparra, JM; Moreno, FJ | 1 |
| Coller, BS; Diacovo, TG; Filizola, M; Jiang, JK; Li, J; Nedelman, M; Negri, A; Shang, Y; Thomas, CJ; Vootukuri, S | 1 |
| Li, W; McIntyre, TM; Silverstein, RL; Srikanthan, S | 1 |
| Cheng, Q; Gailani, D; Ivanov, IS | 1 |
| Bierhansl, L; Butschkau, A; Genz, B; Vollmar, B; Wagner, NM | 1 |
| Carvalho, LP; Chan, MY; Chen, W; Kang, TS; Kini, RM | 1 |
| Etscheid, M; Kanse, SM; Morowski, M; Nieswandt, B; Pragst, I; Sandset, PM; Subramaniam, S; Thielmann, I | 1 |
| Bhakta, V; Eltringham-Smith, LJ; Gataiance, S; Sheffield, WP | 2 |
| Borst, O; Chatterjee, M; Fischer, G; Gawaz, M; Heinzmann, D; Lang, F; Langer, H; Mack, AF; Malešević, M; May, AE; Münzer, P; Schmidt, EM; Schönberger, T; Seizer, P; Ungern-Sternberg, SN | 1 |
| Dong, J; Fang, H; He, S; Huang, K; Kushwaha, KK; Li, D; Lin, J; Mohabeer, N; Su, Y; Wang, B; Wu, C | 1 |
| Kanse, SM; Subramaniam, S | 1 |
| Andre, P; Bentley, R; Cai, TQ; Chen, Z; Desai, K; DiPietro, M; Hoos, L; Jochnowitz, N; Lai, K; Leander, K; Levorse, J; Metzger, JM; Seiffert, D; Sepp-Lorenzino, L; Shin, MK; Strapps, WR; Tadin-Strapps, M; Thankappan, A; Wu, W; Xu, Y; Zhang, Z; Zhou, Y | 1 |
| Chong, CM; Chu, IK; Cui, G; Guo, L; Hoi, MP; Lee, SM; Li, G; Quan, Q; Shan, L; Sun, Y; Wang, Y; Yu, P; Zhang, Z; Zhao, Y | 1 |
| Kong, X; Sheng, L; Wang, T; Xia, L; Xie, H; Xie, Y; Yan, J; Zhou, H | 1 |
| Bonnard, T; Hagemeyer, CE | 1 |
| Bentley, R; Cai, TQ; Chen, Z; Hoos, L; Jochnowitz, N; Metzger, JM; Ogletree, ML; Seiffert, DA; Shin, MK; Strapps, W; Tadin-Strapps, M; Thankappan, A; Wu, W; Xu, Y; Zhou, Y | 1 |
| Alzoubi, K; Borst, O; Chatterjee, M; Chen, H; Elvira, B; Föller, M; Gawaz, M; Lang, F; Liu, G; Luo, D; Mak, TW; Münzer, P; Umbach, AT; Voelkl, J; Walker, B | 1 |
| Gupta, N; Li, W; McIntyre, TM | 1 |
| Jackson, SP; Schoenwaelder, SM | 1 |
| Chu, L; Desai, K; Gutstein, DE; Kurowski, S; Seiffert, D; Wang, X; Wu, W; Zhou, X | 1 |
| Chepurko, E; Covarrubias, R; Cowan, PJ; Dwyer, KM; Gumina, RJ; Huttinger, R; Huttinger, ZM; Novitskaya, T; Reynolds, A; Robson, SC; Stanfill, K; Wheeler, DG | 1 |
| Chauhan, AK; Dhanesha, N; Doddapattar, P; Khanna, I; Nayak, MK; Pollpeter, MJ; Prakash, P; Staber, JM | 1 |
| Huo, Z; Li, C; Wang, R; Wang, Z; Zhao, Z | 1 |
| Yang, Q; Ye, Y; Zhao, C; Zhao, J | 1 |
| Cai, S; Chen, L; Jiang, S; Shi, Y; Wu, Z; Zhu, R; Zou, X | 1 |
| Ambily, A; Authi, KS; Bender, M; Braun, A; Dietrich, A; Gudermann, T; Hassock, SR; Nieswandt, B; Varga-Szabo, D | 1 |
| Chuah, MK; De Meyer, SF; Deckmyn, H; Lenting, PJ; Pareyn, I; Petrus, I; VandenDriessche, T; Vandeputte, N; Vanhoorelbeke, K | 1 |
| Bae, ON; Chung, JH; Chung, SM; Hong, S; Kim, K; Kim, YD; Lim, KM; Noh, JY; Shin, S; Yoon, JH | 1 |
| Bhatt, S; Jain, MR; Patel, PR; Sharma, A; Soni, H | 1 |
| Denofrio, JC; Gentry, HR; Parise, LV; Temple, BR; Yuan, W | 1 |
| Dohare, P; Kalita, J; Misra, UK; Ray, M; Srivastava, AK | 1 |
| Chamberlain, J; Crosdale, DJ; Evans, DJ; Francis, SE; Jackman, LE; Jetha, K; Judge, HM; Norman, KE; Storey, RF | 1 |
| Dieudé, M; Gillis, MA; Lajoie, G; Levine, JS; Merhi, Y; Rauch, J; Théorêt, JF; Thorin, E | 1 |
| Jia, LY; Ju, G; Shen, XF; Zhang, YK; Zhao, Y | 1 |
| Chung, AD; Funk, CD; Mewburn, JD; Seta, F; Turner, PV; Yu, Y | 1 |
| Gupta, RK; Haris, M; Kalita, J; Misra, UK; Srivastava, AK | 1 |
| Møller, F; Tranholm, M | 1 |
| Furie, B | 1 |
| Cabou, C; Chicanne, G; Gratacap, MP; Guillermet-Guibert, J; Jandrot-Perrus, M; Martin, V; Payrastre, B; Plantavid, M; Vanhaesebroeck, B | 1 |
| Esmon, CT; Granger, DN; Kirchhofer, D; Mackman, N; Nagai, M; Yilmaz, CE | 1 |
| Cheng, YS; Chien, CT; Huang, SC; Li, PC; Liu, KH; Tsai, YF | 1 |
| Bagiada, NA; Darmadipura, S; Golden, N | 1 |
| Golder, M; Hegadorn, C; Laverty, K; Lillicrap, D; Mewburn, J; Pruss, CM; Sponagle, K | 1 |
| Gross, PL; Kretz, CA; Vaezzadeh, N | 1 |
| Baumgartner, B; Eder, B; Jaki, T; Muchitsch, EM; Schiviz, A; Schwarz, HP; Wolfsegger, MJ | 1 |
| Kao, CY; Kao, JT; Lin, CN; Lin, SW; Shi, GY; Tao, MH; Wu, HL; Yang, YL; Yu, IS | 1 |
| Mousa, SA | 1 |
| Elg, M; Johansson, K; Kjaer, M; Pehrsson, S | 1 |
| Chatterjee, M; Hu, H; Huang, Z; Ji, Q; Li, N; Zhang, W; Zhu, L | 1 |
| Akkerman, JW; Cate, HT; Hauer, AD; Hildebrand, RB; Hoekstra, M; Korporaal, SJ; Kuiper, J; Meurs, I; Praticò, D; Van Berkel, TJ; Van Eck, M | 1 |
| Cardenas, JC; Church, FC; Krishnamurthy, J; Owens, AP; Sharpless, NE; Whinna, HC | 1 |
| Cazenave, JP; Eckly, A; Freund, M; Gachet, C; Hechler, B; Lanza, F; Mangin, PH; Zerr, M | 1 |
| Cardenas, JC; Church, FC; Machlus, KR; Wolberg, AS | 1 |
| Bode, C; Duerschmied, D; Meißner, M; Neudorfer, I; Peter, K; Roming, F; von Elverfeldt, D; von Zur Muhlen, C; Zirlik, A | 1 |
| Benguigui, LE; Deeb, RS; Hajjar, DP; Hajjar, KA; Lamon, BD; Shen, H; Upmacis, RK | 1 |
| Hagemeyer, CE; Heidt, T; Jackson, KE; Jia, F; Leitner, E; Nair, AK; Pearce, H; Peter, K; Prabhu, S; Ta, HT; von Elverfeldt, D; von Zur Muhlen, C; Wang, X | 1 |
| Jin, SY; Sorvillo, N; Voorberg, J; Xiao, J; Xue, J; Zheng, XL | 1 |
| Fay, WP; Gachet, C; Lu, Y; Mackman, N; Owens, AP; Whinna, HC | 1 |
| Kim, JK; Kwon, OC; Lee, S; Min, SK; Park, KH | 1 |
| Banda, NK; Fujita, T; La Bonte, LR; Pavlov, VI; Stahl, GL; Takahashi, K; Takahashi, M; Tan, YS; Zou, C | 1 |
| Braun, A; Dietrich, A; Gupta, S; Mannhalter, C; May, F; Nieswandt, B; Pleines, I; Ramanathan, G; Thielmann, I; Varga-Szabo, D | 1 |
| Aghourian, MN; Blostein, MD; Lemarié, CA | 1 |
| Christophe, OD; de Groot, PG; Denis, CV; Lenting, PJ; Odouard, S; Oortwijn, BD; Pegon, JN; Saint-Lu, N | 1 |
| Diaz, JA; Henke, PK; Mackman, N; Myers, DD; Obi, AT; Wakefield, TW; Wrobleski, SK | 1 |
| Bryant, A; Golder, M; Haberichter, S; Hegadorn, C; Lillicrap, D; Pruss, CM | 1 |
| Barbera, F; Bird, JE; Revelli, JP; Schumacher, WA; Seiffert, D; Smith, PL; Wang, X | 1 |
| Boulaftali, Y; Bouton, MC; Ho-Tin-Noé, B; Jandrot-Perrus, M; Lamrani, L; Loyau, S; Rouzaud, MC | 1 |
| Han, SM; Kim, HT; Kim, JK; Kwon, OC; Lee, S; Min, SK | 1 |
| Buczko, W; Kalaska, B; Kaminski, K; Kramkowski, K; Mogielnicki, A; Nowakowska, M; Sokolowska, E; Szczubialka, K | 1 |
| Ban, X; Dong, N; Hu, S; Sun, Y; Tian, J; Wu, J; Yu, B; Yu, H | 1 |
| Bhayana, B; Hara, T; Jaffer, FA; Kessinger, CW; Khatri, A; Lin, CP; McCarthy, JR; Tearney, GJ; Thompson, B; Weissleder, R | 1 |
| Fitzgerald, ME; Gartner, TK; Joglekar, MV; Ware, J; Xu, J | 1 |
| Crescente, M; Demers, M; Ho-Tin-Noé, B; Thomas, GM; Voorhees, JR; Wagner, DD; Wong, SL | 1 |
| Assumpção, TC; Collin, N; Dutra-Oliveira, A; Francischetti, IM; Gilmore, DC; Kotsyfakis, M; Mizurini, DM; Monteiro, RQ; Ribeiro, JM; Sá-Nunes, A; Teixeira, C; Valenzuela, JG | 1 |
| Ding, Z; Hu, L; Kunapuli, SP; Li, Y; Ye, J; Zhang, S; Zhang, SH; Zhang, Y | 1 |
| Casari, C; Christophe, OD; Denis, CV; Hu, JR; Legendre, P; Lenting, PJ; Marx, I; Navarrete, AM | 1 |
| Henke, PK; Jaffer, FA; Kessinger, CW; Kim, JW; Li, C; Lin, CP; McCarthy, JR; Ripplinger, CM; Weissleder, R | 1 |
| Kohanawa, M; Kuge, Y; Tamaki, N; Tao, H; Zhao, S | 1 |
| Chen, D; Chen, S; Fan, CL; Huang, JF; Liu, P; Shang, L; Wang, H; Xiong, K; Zhang, MQ | 1 |
| Golder, M; Lillicrap, D; Mewburn, J | 1 |
| Rossaint, J; Vestweber, D; Zarbock, A | 1 |
| Barr, JD; Chauhan, AK; Hansen, JK; Motto, DG; Schaeffer, GV | 1 |
| Dellas, C; Hasenfuss, G; Konstantinides, S; Loskutoff, DJ; Müller, K; Riedel, C; Schäfer, K; Thinnes, T | 1 |
| Hong, J; Junxia, X; Ming, Q; Wenfang, C | 1 |
| Doi, T; Tokumaru, J; Ueda, Y; Willmore, LJ | 1 |
| Kong, W; Luo, Z; Peng, H; Zhang, X | 1 |
| Cooley, BC; Hendrickson, SB; Hernandez, I; Isermann, BH; Kerlin, B; Lord, S; Mosesson, MW; Sood, R; Weiler, H; Zogg, M | 1 |
| Dellas, C; Goeschen, C; Halle, M; Konstantinides, S; Loskutoff, DJ; Pynn, M; Schäfer, K | 1 |
| Bickel, DJ; Lyle, EA; Lynch, JJ; Robinson, MA; Welsh, DC | 1 |
| Lee, JK; Meyerhoff, JL; Rittase, BW; Tsang, AY; Yourick, DL | 1 |
| Golubykh, VL; Maksimenko, AV; Tischenko, EG | 1 |
| Wang, X; Xu, L | 1 |
| Bachmann, G; Gerriets, T; Heil, M; Kaps, M; Madlener, K; Röttger, C; Stolz, E; Walberer, M; Wessels, T | 1 |
| Budihna, MV; Cerne, M; Drevensek, G; Peternel, L; Stalc, A; Stegnar, M | 1 |
| D'Orio, V; Dogné, JM; Drion, P; Ghuysen, A; Hanson, J; Kolh, P; Lambermont, B; Magis, D; Masereel, B; Pétein, M; Pirotte, B; Rolin, S; Segers, P; Tchana-Sato, V | 1 |
| Bachmann, G; Gerriets, T; Kaps, M; Kuchelmeister, K; Röttger, C; Schachenmayr, W; Stolz, E; Walberer, M; Wessels, T | 1 |
| Alonso-Escolano, D; Drews, M; Jurasz, P; Malinski, T; Morandi, M; Radomski, A; Radomski, MW | 1 |
| Chen, CY; Cooley, BC; Schmeling, G; Schwab, JP; Szema, L | 1 |
| Hsu, MY; Ogletree, ML; Schumacher, WA; Smith, PL; Wang, X | 1 |
| Kong, Q; Sun, S; Tong, E; Yao, Y | 1 |
| Chen, CY; Cooley, BC; Schmeling, G | 1 |
| Hsu, MY; Monticello, TM; Schumacher, WA; Steinbacher, TE; Wang, X | 1 |
| Branco, LG; Dias, MB; Raffaini, MS | 1 |
| Gailani, D; Hsu, MY; Ogletree, ML; Schumacher, WA; Seiffert, DA; Smith, PL; Wang, X | 1 |
| Almus-Jacobs, F; Konstantinides, S; Loskutoff, DJ; Marchese, P; Ruggeri, ZM; Ware, J | 1 |
| Bird, E; Hsu, MY; Schumacher, WA; Smith, PL; Tamasi, JA; Wang, X | 1 |
| Hayashi, H; Ito, H; Nagamura, Y; Sudo, T; Toga, K; Yamada, Y | 1 |
| Doi, T; Nagatomo, K; Nakajima, A; Ueda, Y; Willmore, LJ | 1 |
| Doi, T; Nagatomo, K; Nakajima, A; Takaki, M; Ueda, Y; Willmore, LJ; Yokoyama, H | 1 |
| Eitzman, DT; Westrick, RJ; Winn, ME | 1 |
| Bevers, E; Bruggemann, L; Hansen, HR; Hauer, AD; Kuiper, J; Reitsma, PH; Sommeijer, DW; Spek, CA; Spronk, HM; ten Cate, H; Wolfs, JL | 1 |
| August, S; Li, D; Woulfe, DS | 1 |
| Guha, D; Hazra, R; Ray, K | 1 |
| Berges, A; Humboldt, T; Konstantinides, S; Lebrun, S; Leifheit, M; Meurrens, K; Sawalich, M; Schaefer, K; Schleef, R; Schroeter, MR; Wallerath, T; Xu, H | 1 |
| Wang, X | 1 |
| Allievi, E; Banfi, S; Fonio, W; Raimondo, S | 1 |
| Broersma, RJ; Heminger, EF; Kutcher, LW; Lintz, C; Neises, B; Piriou, F; Remy, JM; Tarnus, C | 1 |
| Alvarez de Cienfuegos, G; Alvarez, C; de Pablo, M; Gallego, AM; Ortega, E; Pancorbo, PL | 1 |
| Hiramatsu, M; Kadowaki, D; Kadoya, K; Kinno, I; Mori, A | 1 |
| Drader, J; Hirsch, D; Levy, RJ; Pathak, YV; Schoen, FJ; Yee, R | 1 |
| Liu, XG; Xu, LN | 1 |
| Crowe, A; Morgan, EH | 1 |
| Habu, H; Kabuto, H; Mori, A; Ogawa, N; Willmore, LJ; Yokoi, I | 1 |
| Chen, W; Levy, RJ; Myers, DJ; Schoen, FJ | 1 |
| Brown, JS; Gilliland, SM; Holden, DW | 1 |
| Blunt, SB; Datla, KP; Dexter, DT | 1 |
| Coller, BS; Reis, ED; Smyth, SS; Väänänen, H; Zhang, W | 1 |
| Calvio, AM; Colli, S; Mussoni, L; Sironi, L; Tedeschi, L; Tremoli, E | 1 |
| Kurz, KD; Main, BW; Sandusky, GE | 1 |
8 review(s) available for ferric chloride and Disease Models, Animal
| Article | Year |
|---|---|
How useful are ferric chloride models of arterial thrombosis?
Topics: Animals; Anticoagulants; Blood Platelets; Carotid Artery Thrombosis; Chlorides; Disease Models, Animal; Erythrocytes; Ferric Compounds; Humans; Mice; Mice, Knockout | 2020 |
By word of mouse: using animal models in venous thrombosis research.
Topics: Animals; Chlorides; Constriction, Pathologic; Disease Models, Animal; Femoral Vein; Ferric Compounds; Ligation; Mice; Pulmonary Embolism; Vena Cava, Inferior; Venous Thrombosis | 2020 |
Atherosclerotic plaque injury-mediated murine thrombosis models: advantages and limitations.
Topics: Animals; Atherosclerosis; Blood Coagulation; Blood Platelets; Carotid Artery Thrombosis; Chlorides; Diet, High-Fat; Disease Models, Animal; Ferric Compounds; Humans; Ligation; Mice; Mice, Knockout, ApoE; Plaque, Atherosclerotic; Ultrasonic Waves | 2020 |
Involvement of neutrophils in thrombus formation in living mice.
Topics: Animals; Arteries; Blood Proteins; Chlorides; Computer Systems; Cytoplasmic Granules; Disease Models, Animal; Endothelium, Vascular; Extracellular Matrix; Ferric Compounds; Lasers; Mice; Microcirculation; Neutrophil Infiltration; Neutrophils; Platelet Activation; Thromboplastin; Thrombosis | 2014 |
Pathogenesis of thrombosis.
Topics: Animals; Blood Coagulation Factors; Cell-Derived Microparticles; Chlorides; Collagen; Disease Models, Animal; Ferric Compounds; Fibrin; Integrin beta3; Lasers; Mesentery; Mice; Mice, Knockout; Microscopy, Fluorescence; Muscle, Skeletal; Platelet Aggregation; Protein Disulfide-Isomerases; Thromboplastin; Thrombosis | 2009 |
Tissue factor and thrombosis models.
Topics: Animals; Blood Coagulation; Blood Vessels; Chlorides; Disease Models, Animal; Evidence-Based Medicine; Ferric Compounds; Genotype; Mice; Mice, Transgenic; Phenotype; Reproducibility of Results; Thromboplastin; Thrombosis | 2010 |
Critical review of mouse models of venous thrombosis.
Topics: Animals; Chlorides; Constriction; Disease Models, Animal; Electrolysis; Ferric Compounds; Ligation; Mice; Vena Cava, Inferior; Venous Thrombosis | 2012 |
Murine models of vascular thrombosis (Eitzman series).
Topics: Animals; Atherosclerosis; Blood Coagulation; Blood Vessels; Chlorides; Collagen; Disease Models, Animal; Epinephrine; Ferric Compounds; Genotype; Lasers; Mice; Mice, Transgenic; Microscopy, Fluorescence; Microscopy, Video; Phenotype; Reproducibility of Results; Rose Bengal; Species Specificity; Thrombosis | 2007 |
160 other study(ies) available for ferric chloride and Disease Models, Animal
| Article | Year |
|---|---|
A synthetic heparin mimetic that allosterically inhibits factor XIa and reduces thrombosis in vivo without enhanced risk of bleeding.
Topics: Allosteric Regulation; Animals; Anticoagulants; Blood Coagulation; Chlorides; Disease Models, Animal; Factor XIa; Female; Ferric Compounds; Hemorrhage; Heparin; Humans; Inositol; Molecular Mimicry; Rats, Wistar; Risk Assessment; Sulfates; Thrombosis | 2019 |
Motor deficit in the mouse ferric chloride-induced distal middle cerebral artery occlusion model of stroke.
Topics: Animals; Behavior, Animal; Cerebral Cortex; Cerebral Infarction; Chlorides; Disease Models, Animal; Female; Ferric Compounds; Infarction, Middle Cerebral Artery; Male; Mice; Mice, 129 Strain; Motor Activity; Sex Characteristics; Stroke | 2020 |
Cyclic peptide FXII inhibitor provides safe anticoagulation in a thrombosis model and in artificial lungs.
Topics: Animals; Anticoagulants; Blood Coagulation; Chlorides; Cloning, Molecular; Disease Models, Animal; Drug Discovery; Extracorporeal Membrane Oxygenation; Factor XII; Factor XIIa; Female; Ferric Compounds; Humans; Lung; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptides, Cyclic; Rabbits; Recombinant Proteins; Swine; Thrombosis | 2020 |
Mice Lacking the Inhibitory Collagen Receptor LAIR-1 Exhibit a Mild Thrombocytosis and Hyperactive Platelets.
Topics: Animals; Blood Platelets; Carrier Proteins; Cells, Cultured; Chlorides; Disease Models, Animal; Enzyme Activation; Ferric Compounds; Genetic Predisposition to Disease; Megakaryocytes; Mice, Knockout; Peptides; Phenotype; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoproteins; Receptors, IgG; Receptors, Immunologic; Signal Transduction; src-Family Kinases; Thrombocytosis; Thrombosis | 2017 |
Potent Thrombolytic Effect of
Topics: Acetylcysteine; Animals; Blood Platelets; Chlorides; Disease Models, Animal; Ferric Compounds; Fibrinolytic Agents; Infarction, Middle Cerebral Artery; Male; Mice; Platelet Aggregation; Ristocetin; Thromboembolism; Thrombosis; Tissue Plasminogen Activator; von Willebrand Factor | 2017 |
Trowaglerix Venom Polypeptides As a Novel Antithrombotic Agent by Targeting Immunoglobulin-Like Domains of Glycoprotein VI in Platelet.
Topics: Animals; Binding Sites; Blood Platelets; Carotid Artery Injuries; Chlorides; Computer-Aided Design; Crotalid Venoms; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Ferric Compounds; Fibrinolytic Agents; Fluorescein; Hemorrhage; Humans; Lectins, C-Type; Male; Mice, Inbred ICR; Molecular Docking Simulation; Peptide Fragments; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Protein Binding; Protein Interaction Domains and Motifs; Signal Transduction; Thrombosis | 2017 |
Platelets Express Activated P2Y
Topics: Adenosine Monophosphate; Animals; Blood Platelets; Cell Adhesion Molecules; Cell Line; Chlorides; Cyclic AMP; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Drug Inverse Agonism; Ferric Compounds; Fibrinolytic Agents; Humans; Male; Microfilament Proteins; NF-kappa B; Phosphoproteins; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, Purinergic P2Y12; Thrombosis | 2017 |
Interferon lambda1/IL-29 and inorganic polyphosphate are novel regulators of neutrophil-driven thromboinflammation.
Topics: Animals; Autophagy; Blood Coagulation; Blood Platelets; Case-Control Studies; Chlorides; Disease Models, Animal; Extracellular Traps; Ferric Compounds; Humans; Inflammation; Interferons; Interleukins; Male; Mice, Inbred C57BL; Neutrophils; Platelet Activation; Polyphosphates; Signal Transduction; ST Elevation Myocardial Infarction; Thrombin; Thrombosis; TOR Serine-Threonine Kinases | 2017 |
Photoacoustic Imaging: A Novel Tool for Detecting Carotid Artery Thrombosis in Mice.
Topics: Animals; Biopsy; Carotid Artery Diseases; Carotid Artery, Common; Chlorides; Disease Models, Animal; Ferric Compounds; Male; Mice, Inbred ICR; Photoacoustic Techniques; Predictive Value of Tests; Thrombosis; Time Factors; Ultrasonography, Doppler, Color | 2017 |
ADPase CD39 Fused to Glycoprotein VI-Fc Boosts Local Antithrombotic Effects at Vascular Lesions.
Topics: Animals; Antigens, CD; Apyrase; Carotid Artery Diseases; Carotid Artery Injuries; Chlorides; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Ferric Compounds; Fibrinolytic Agents; Glycoproteins; Hemorrhage; Humans; Immunoglobulin Fc Fragments; Male; Mice, Inbred C57BL; Plaque, Atherosclerotic; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Recombinant Fusion Proteins; Thrombosis | 2017 |
ARHGEF10 knockout inhibits platelet aggregation and protects mice from thrombus formation.
Topics: Animals; Arterial Occlusive Diseases; Blood Platelets; Carotid Artery Diseases; Cell Shape; Chlorides; Disease Models, Animal; Ferric Compounds; Gene Knockout Techniques; Genotype; Hemostasis; Male; Mice, 129 Strain; Mice, Knockout; Myosin Light Chains; Phenotype; Phosphorylation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Rho Guanine Nucleotide Exchange Factors; Selenoprotein P; Thrombosis; Time Factors | 2017 |
Class III PI3K Positively Regulates Platelet Activation and Thrombosis via PI(3)P-Directed Function of NADPH Oxidase.
Topics: Adult; Animals; Autophagy; Blood Coagulation; Blood Platelets; Chlorides; Class III Phosphatidylinositol 3-Kinases; Collagen; Disease Models, Animal; Female; Ferric Compounds; Genotype; Humans; Male; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Phenotype; Phosphatidylinositol Phosphates; Platelet Activation; Platelet Aggregation; Reactive Oxygen Species; Signal Transduction; Thrombin; Thrombosis; Time Factors; TOR Serine-Threonine Kinases; Young Adult | 2017 |
Edoxaban improves venous thrombosis via increasing hydrogen sulfide and homocysteine in rat model.
Topics: Animals; Anticoagulants; Chlorides; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Endothelial Cells; Ferric Compounds; Gene Expression Regulation; Homocysteine; Hydrogen Sulfide; Male; Matrix Metalloproteinase 9; Phosphatidylinositol 3-Kinases; Primary Cell Culture; Proto-Oncogene Proteins c-akt; Pyridines; Rats; Rats, Sprague-Dawley; Signal Transduction; Thiazoles; Venous Thrombosis | 2017 |
A rabbit model of cerebral venous sinus thrombosis established by ferric chloride and thrombin injection.
Topics: Animals; Blood-Brain Barrier; Brain; Chlorides; Disease Models, Animal; Ferric Compounds; Male; Rabbits; Sinus Thrombosis, Intracranial; Thrombin | 2018 |
Histological comparison of arterial thrombi in mice and men and the influence of Cl-amidine on thrombus formation.
Topics: Aged; Animals; Chlorides; Coronary Vessels; Disease Models, Animal; Female; Ferric Compounds; Humans; Male; Mice; Middle Aged; Myocardial Infarction; Ornithine; Prospective Studies; Thrombosis | 2018 |
Targeting Germinal Matrix Hemorrhage-Induced Overexpression of Sodium-Coupled Bicarbonate Exchanger Reduces Posthemorrhagic Hydrocephalus Formation in Neonatal Rats.
Topics: Animals; Animals, Newborn; Behavior, Animal; Cerebral Hemorrhage; Cerebrospinal Fluid; Chlorides; Choroid Plexus; Cognition; Deferoxamine; Disease Models, Animal; Ferric Compounds; Hydrocephalus; Injections, Intraventricular; Iron Regulatory Protein 1; Iron Regulatory Protein 2; Motor Activity; Rats, Sprague-Dawley; RNA, Small Interfering; RNAi Therapeutics; Siderophores; Sodium-Bicarbonate Symporters | 2018 |
Inducible Knockdown of Endothelial Protein Tyrosine Phosphatase-1B Promotes Neointima Formation in Obese Mice by Enhancing Endothelial Senescence.
Topics: Animals; Apoptosis; Cell Line; Chlorides; Chromans; Disease Models, Animal; Endothelial Cells; Ferric Compounds; Gene Knockdown Techniques; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Obese; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neointima; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Re-Epithelialization; Tamoxifen; Vascular System Injuries; Wound Healing | 2019 |
Fusion to Human Serum Albumin Extends the Circulatory Half-Life and Duration of Antithrombotic Action of the Kunitz Protease Inhibitor Domain of Protease Nexin 2.
Topics: Amyloid beta-Protein Precursor; Animals; Area Under Curve; Blood Coagulation Factors; Chlorides; Chromatography, High Pressure Liquid; Disease Models, Animal; Ferric Compounds; Half-Life; Histidine; Humans; Iodine Radioisotopes; Mice; Oligopeptides; Protein Domains; Receptors, LDL; Recombinant Fusion Proteins; ROC Curve; Serum Albumin, Human; Spectrometry, Mass, Electrospray Ionization; Thrombosis | 2018 |
Evaluation of the antithrombotic activity of Zhi-Xiong Capsules, a Traditional Chinese Medicinal formula, via the pathway of anti-coagulation, anti-platelet activation and anti-fibrinolysis.
Topics: Acute Disease; Animals; Anticoagulants; Antithrombins; Aspirin; Blood Coagulation; Capsules; Carotid Arteries; Chlorides; Disease Models, Animal; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Ferric Compounds; Fibrinolysis; Heparin; Lung; Mice; Platelet Activation; Platelet Aggregation; Prostaglandins F; Pulmonary Embolism; Rabbits; Rats, Sprague-Dawley; Thrombolytic Therapy; Thrombosis; Thromboxane B2 | 2018 |
Endothelial progenitor cell-derived exosomes, loaded with miR-126, promoted deep vein thrombosis resolution and recanalization.
Topics: Animals; Base Sequence; Bone Marrow Cells; Cadherins; Cell Movement; Cellular Senescence; Chlorides; Disease Models, Animal; Electroporation; Endothelial Progenitor Cells; Epidermal Growth Factor; Exosomes; Ferric Compounds; Insulin-Like Growth Factor I; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Primary Cell Culture; Protocadherins; Ribonucleotides; Vena Cava, Inferior; Venous Thrombosis | 2018 |
Ferric Chloride-induced Canine Carotid Artery Thrombosis: A Large Animal Model of Vascular Injury.
Topics: Animals; Carotid Artery Thrombosis; Chlorides; Disease Models, Animal; Dogs; Ferric Compounds; Humans; Male; Vascular System Injuries | 2018 |
Choosing a Mouse Model of Venous Thrombosis.
Topics: Algorithms; Animals; Chlorides; Disease Models, Animal; Electrolysis; Endothelial Cells; Endothelium, Vascular; Ferric Compounds; Free Radicals; Hemorheology; Ligation; Mice; Recurrence; Research Design; Veins; Venous Thrombosis; Venules | 2019 |
Anti-PEG Antibodies Inhibit the Anticoagulant Activity of PEGylated Aptamers.
Topics: Animals; Antibodies; Anticoagulants; Antigen-Antibody Reactions; Aptamers, Nucleotide; Chlorides; Disease Models, Animal; Factor IXa; Female; Ferric Compounds; Humans; Macaca mulatta; Mice; Mice, Inbred C57BL; Partial Thromboplastin Time; Polyethylene Glycols; Thrombosis | 2019 |
Antithrombotic Activity of a Novel Diazepino[1,2-α] Benzimidazole Derivative on Arterial Thrombosis Model in Rats without Concomitant Pathology and in Rats with Experimental Myocardial Infarction.
Topics: Animals; Animals, Outbred Strains; Aspirin; Azepines; Benzimidazoles; Blood Coagulation Tests; Chlorides; Clopidogrel; Disease Models, Animal; Ferric Compounds; Fibrinolytic Agents; Male; Myocardial Infarction; Platelet Aggregation; Rats; Thrombosis | 2019 |
Elevated prothrombin promotes venous, but not arterial, thrombosis in mice.
Topics: Animals; Blood Coagulation; Blood Platelets; Carotid Arteries; Chlorides; Disease Models, Animal; Femoral Vein; Ferric Compounds; Fibrin; Humans; Mice; Noxae; Prothrombin; Risk Factors; Thrombophilia; Vena Cava, Inferior; Venous Thrombosis | 2013 |
Desmolaris, a novel factor XIa anticoagulant from the salivary gland of the vampire bat (Desmodus rotundus) inhibits inflammation and thrombosis in vivo.
Topics: Animals; Anticoagulants; Bradykinin; Chiroptera; Chlorides; Disease Models, Animal; Factor Xa; Factor Xa Inhibitors; Ferric Compounds; HEK293 Cells; Humans; Inflammation; Kallikreins; Mice; Noxae; Protein Structure, Tertiary; Salivary Proteins and Peptides; Thrombosis | 2013 |
Anfibatide, a novel GPIb complex antagonist, inhibits platelet adhesion and thrombus formation in vitro and in vivo in murine models of thrombosis.
Topics: Animals; Binding Sites; Blood Platelets; Chlorides; Crotalid Venoms; Disease Models, Animal; Female; Ferric Compounds; Fibrinolytic Agents; Hemorrhage; Lectins, C-Type; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIb-IX Complex; Protein Binding; Thrombosis; Time Factors; Vascular System Injuries; von Willebrand Factor | 2014 |
Proteasome proteolysis supports stimulated platelet function and thrombosis.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Cell-Derived Microparticles; Chlorides; Cytoskeletal Proteins; Disease Models, Animal; Ferric Compounds; Fibrinolytic Agents; Filamins; Humans; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation; Platelet Glycoprotein GPIb-IX Complex; Platelet Transfusion; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Proteolysis; Talin; Thrombin; Thrombosis; Time Factors; Ubiquitination | 2014 |
Acid sphingomyelinase regulates platelet cell membrane scrambling, secretion, and thrombus formation.
Topics: Adenosine Triphosphate; Animals; Blood Platelets; Calcium; Cell Degranulation; Cell Membrane; Ceramides; Chlorides; Disease Models, Animal; Enzyme Inhibitors; Female; Ferric Compounds; Fibrinolytic Agents; Male; Mice; Mice, Knockout; P-Selectin; Phosphatidylserines; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Sphingomyelin Phosphodiesterase; Thrombin; Thrombosis; Time Factors | 2014 |
The flavonols quercetin and 3',4'-dihydroxyflavonol reduce platelet function and delay thrombus formation in a model of type 1 diabetes.
Topics: Animals; Antioxidants; Blood Platelets; Carotid Arteries; Carotid Artery Injuries; Chlorides; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Exocytosis; Ferric Compounds; Flavonols; Laser-Doppler Flowmetry; Mice; Mice, Inbred C57BL; Platelet Activation; Platelet Aggregation; Quercetin; Thrombosis | 2014 |
Histopathological effects of different therapy strategies in experimental sinus thrombosis.
Topics: Abciximab; Animals; Antibodies, Monoclonal; Astrocytes; Brain; Chlorides; Collateral Circulation; Disease Models, Animal; Enoxaparin; Factor VIII; Ferric Compounds; Fibrinolytic Agents; Glial Fibrillary Acidic Protein; Immunoglobulin Fab Fragments; Injections, Subcutaneous; Magnetic Resonance Angiography; Male; Neurons; Observer Variation; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Reperfusion; Sinus Thrombosis, Intracranial; Superior Sagittal Sinus; Temporal Lobe; Thrombolytic Therapy; Tissue Plasminogen Activator | 2014 |
Direct interaction of kindlin-3 with integrin αIIbβ3 in platelets is required for supporting arterial thrombosis in mice.
Topics: Amino Acid Substitution; Animals; Bleeding Time; Blood Platelets; Carotid Artery Thrombosis; Cell Shape; Chlorides; Clot Retraction; Cytoskeletal Proteins; Disease Models, Animal; Female; Ferric Compounds; Gene Knock-In Techniques; Genes, Reporter; Male; Mice; Mice, Inbred C57BL; Microspheres; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Interaction Mapping; Recombinant Fusion Proteins | 2014 |
Analysis of the role of von Willebrand factor, platelet glycoprotein VI-, and α2β1-mediated collagen binding in thrombus formation.
Topics: Amino Acid Substitution; Animals; Chlorides; Collagen; Disease Models, Animal; Ferric Compounds; HEK293 Cells; Humans; Integrin alpha2beta1; Mice; Mice, Knockout; Mutation, Missense; Noxae; Platelet Membrane Glycoproteins; Protein Structure, Tertiary; Thrombosis; von Willebrand Factor | 2014 |
Ferric chloride-induced murine carotid arterial injury: A model of redox pathology.
Topics: Animals; Carotid Artery Injuries; Chlorides; Disease Models, Animal; Ferric Compounds; Mice; Mice, Inbred C57BL; Oxidation-Reduction | 2013 |
Structural differences of prebiotic oligosaccharides influence their capability to enhance iron absorption in deficient rats.
Topics: Anemia, Iron-Deficiency; Animals; Chlorides; Dietary Supplements; Disease Models, Animal; Fatty Acids, Volatile; Female; Ferric Compounds; Hemoglobins; Hepcidins; Homeostasis; Interleukin-6; Intestinal Absorption; Iron, Dietary; Liver; Micronutrients; NF-kappa B; PPAR gamma; Prebiotics; Rats; Rats, Wistar; Receptors, Transferrin; RNA, Messenger; Tandem Mass Spectrometry; Trisaccharides | 2014 |
RUC-4: a novel αIIbβ3 antagonist for prehospital therapy of myocardial infarction.
Topics: Animals; Binding Sites; Blood Platelets; Carotid Stenosis; Chlorides; Disease Models, Animal; Emergency Medical Services; Ferric Compounds; Fibrinolytic Agents; Humans; Macaca fascicularis; Male; Mice; Mice, Transgenic; Molecular Dynamics Simulation; Myocardial Infarction; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Protein Conformation; Pyrimidinones; Solubility; Thiadiazoles; Thrombosis; von Willebrand Factor | 2014 |
Exosome poly-ubiquitin inhibits platelet activation, downregulates CD36 and inhibits pro-atherothombotic cellular functions.
Topics: Animals; Blood Platelets; Carotid Artery Diseases; CD36 Antigens; Cell-Derived Microparticles; Chlorides; Cholesterol; Collagen; Disease Models, Animal; Exosomes; Ferric Compounds; Foam Cells; Humans; Lipoproteins, LDL; Mice, Inbred C57BL; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation; Platelet Transfusion; Polyubiquitin; Proteasome Endopeptidase Complex; Proteolysis; Signal Transduction; Thrombocytopenia; Thrombosis; Time Factors; Ubiquitination | 2014 |
Murine models in the evaluation of heparan sulfate-based anticoagulants.
Topics: Animals; Anticoagulants; Chlorides; Disease Models, Animal; Ferric Compounds; Hemorrhage; Heparitin Sulfate; Mice, Inbred C57BL; Tail; Thrombosis; Vena Cava, Inferior | 2015 |
Protein Z-deficiency is associated with enhanced neointima formation and inflammatory response after vascular injury in mice.
Topics: Actins; Animals; Blood Proteins; Carotid Arteries; Carotid Artery Injuries; Cell Movement; Cell Proliferation; Cells, Cultured; Chlorides; Disease Models, Animal; Ferric Compounds; Humans; Inflammation; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neointima; Proliferating Cell Nuclear Antigen; Time Factors; Vascular System Injuries | 2014 |
Fasxiator, a novel factor XIa inhibitor from snake venom, and its site-specific mutagenesis to improve potency and selectivity.
Topics: Amino Acid Sequence; Animals; Binding, Competitive; Blood Coagulation; Bungarotoxins; Bungarus; Carotid Stenosis; Chlorides; Disease Models, Animal; Dose-Response Relationship, Drug; Factor Xa Inhibitors; Factor XIa; Ferric Compounds; Humans; Kinetics; Male; Mice, Inbred C57BL; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Partial Thromboplastin Time; Protein Conformation; Prothrombin Time; Recombinant Proteins; Structure-Activity Relationship; Thrombosis | 2015 |
Defective thrombus formation in mice lacking endogenous factor VII activating protease (FSAP).
Topics: Animals; Blood Coagulation Tests; Carotid Arteries; Carotid Artery Diseases; Chlorides; Collagen; Disease Models, Animal; Ferric Compounds; Genetic Predisposition to Disease; Hemostasis; Jugular Veins; Lipoproteins; Mesenteric Arteries; Mesenteric Vascular Occlusion; Mice, Inbred C57BL; Mice, Knockout; Norepinephrine; Phenotype; Serine Endopeptidases; Thrombosis; Venous Thromboembolism | 2015 |
A plasmin-activatable thrombin inhibitor reduces experimental thrombosis and assists experimental thrombolysis in murine models.
Topics: Animals; Chlorides; Disease Models, Animal; Ferric Compounds; Hirudins; Humans; Mice; Rabbits; Recombinant Proteins; Thrombolytic Therapy; Thrombosis | 2015 |
Extracellular cyclophilin A activates platelets via EMMPRIN (CD147) and PI3K/Akt signaling, which promotes platelet adhesion and thrombus formation in vitro and in vivo.
Topics: Animals; Basigin; Blood Platelets; Carotid Artery Injuries; Cell Degranulation; Chlorides; Cyclophilin A; Disease Models, Animal; Dose-Response Relationship, Drug; Ferric Compounds; Fibrinolytic Agents; Humans; Mice, Inbred C57BL; Mice, Knockout; Phosphatidylinositol 3-Kinases; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Proto-Oncogene Proteins c-akt; Signal Transduction; Thrombosis; Time Factors | 2015 |
Inflammatory cytokine TSLP stimulates platelet secretion and potentiates platelet aggregation via a TSLPR-dependent PI3K/Akt signaling pathway.
Topics: Androstadienes; Animals; Blood Platelets; Carotid Artery Thrombosis; Chlorides; Chromones; Cytokines; Disease Models, Animal; Ferric Compounds; Humans; Immunoglobulins; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; P-Selectin; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Proto-Oncogene Proteins c-akt; Receptors, Cytokine; Signal Transduction; Thymic Stromal Lymphopoietin; Wortmannin | 2015 |
Ferric chloride-induced arterial thrombosis in mice.
Topics: Animals; Carotid Arteries; Carotid Artery Thrombosis; Chlorides; Disease Models, Animal; Dissection; Ferric Compounds; Humans; Mice; Mice, Inbred C57BL; Specimen Handling | 2014 |
Titrating haemophilia B phenotypes using siRNA strategy: evidence that antithrombotic activity is separated from bleeding liability.
Topics: Animals; Cell Line; Chlorides; Disease Models, Animal; Factor IX; Ferric Compounds; Gene Expression Regulation; Genotype; Hemophilia B; Hemorrhage; Hemostasis; Liver; Male; Phenotype; Rats; Rats, Sprague-Dawley; Rats, Transgenic; RNA Interference; RNA, Messenger; RNA, Small Interfering; RNAi Therapeutics; Thrombosis; Time Factors; Transfection | 2015 |
Novel anti-thrombotic agent for modulation of protein disulfide isomerase family member ERp57 for prophylactic therapy.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Cell Adhesion Molecules; Chlorides; Disease Models, Animal; Enzyme Activation; Ferric Compounds; Fibrinolytic Agents; Gene Expression Regulation; Heme Oxygenase-1; Humans; Lactates; Microfilament Proteins; Models, Biological; P-Selectin; Phosphoproteins; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Protein Disulfide-Isomerases; Proteomics; Rats; Thrombosis; Venous Thrombosis | 2015 |
TLR4 is involved in the pathogenic effects observed in a murine model of antiphospholipid syndrome.
Topics: Animals; Antibodies, Antiphospholipid; Antiphospholipid Syndrome; beta 2-Glycoprotein I; Carotid Artery Thrombosis; Cell Adhesion; Chlorides; Disease Models, Animal; E-Selectin; Femoral Vein; Ferric Compounds; Immunoglobulin G; Inflammation Mediators; Intercellular Adhesion Molecule-1; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Mice; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1; Venous Thrombosis | 2015 |
Ferric Chloride-induced Thrombosis Mouse Model on Carotid Artery and Mesentery Vessel.
Topics: Animals; Carotid Artery Thrombosis; Chlorides; Disease Models, Animal; Ferric Compounds; Male; Mesentery; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Thrombosis | 2015 |
Factor XII full and partial null in rat confers robust antithrombotic efficacy with no bleeding.
Topics: Animals; Arteriovenous Shunt, Surgical; Chlorides; Disease Models, Animal; Dose-Response Relationship, Drug; Ellagic Acid; Endodeoxyribonucleases; Factor XII; Ferric Compounds; Gene Knockout Techniques; Hemorrhage; Humans; Liver; Male; Partial Thromboplastin Time; Rats; Rats, Sprague-Dawley; RNA, Messenger; RNA, Small Interfering; Thrombin; Thrombolytic Therapy; Thrombosis; Zinc Fingers | 2015 |
CD44 sensitivity of platelet activation, membrane scrambling and adhesion under high arterial shear rates.
Topics: Animals; Apoptosis; Blood Coagulation; Blood Platelets; Calcium Channels; Calcium Signaling; Caspase 3; Cell Degranulation; Cell Membrane; Chlorides; Disease Models, Animal; Female; Ferric Compounds; Genotype; Hyaluronan Receptors; Male; Mechanotransduction, Cellular; Mice, Knockout; ORAI1 Protein; Phenotype; Phospholipids; Platelet Adhesiveness; Platelet Glycoprotein GPIIb-IIIa Complex; Regional Blood Flow; Selenoprotein P; Stress, Mechanical; Thrombin; Thrombosis | 2016 |
Deubiquitinases Modulate Platelet Proteome Ubiquitination, Aggregation, and Thrombosis.
Topics: Aminopyridines; Animals; Benzoates; Blood Platelets; Chlorides; Disease Models, Animal; Enzyme Inhibitors; Ferric Compounds; Furans; Humans; Mice, Inbred C57BL; Microfluidic Analytical Techniques; Microscopy, Interference; Piperidones; Platelet Aggregation; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Proteasome Endopeptidase Complex; Pyrazoles; Receptors, Collagen; Receptors, Thrombin; Signal Transduction; Thiocyanates; Thrombosis; Ubiquitin Thiolesterase; Ubiquitin-Specific Proteases; Ubiquitination | 2015 |
Ferric chloride thrombosis model: unraveling the vascular effects of a highly corrosive oxidant.
Topics: Animals; Caustics; Chlorides; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Erythrocyte Aggregation; Erythrocytes; Ferric Compounds; Mice; Oxidants; Platelet Activation; Thrombosis | 2015 |
A rabbit model of cerebral microembolic signals for translational research: preclinical validation for aspirin and clopidogrel.
Topics: Animals; Aspirin; Carotid Artery Thrombosis; Chlorides; Clopidogrel; Disease Models, Animal; Drug Evaluation, Preclinical; Ferric Compounds; Fibrinolytic Agents; Intracranial Embolism; Male; Middle Cerebral Artery; Platelet Aggregation; Rabbits; Stroke; Ticlopidine; Translational Research, Biomedical; Ultrasonography; Ultrasonography, Doppler | 2016 |
Role of the CD39/CD73 Purinergic Pathway in Modulating Arterial Thrombosis in Mice.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Arterial Occlusive Diseases; Blood Coagulation; Bone Marrow Transplantation; Chlorides; Disease Models, Animal; Endothelial Cells; Ferric Compounds; Genetic Predisposition to Disease; HEK293 Cells; Humans; Hydrolysis; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Monocytes; Phenotype; Platelet Activation; Thrombosis; Time Factors; Transfection | 2016 |
Endothelial Cell-Derived von Willebrand Factor Is the Major Determinant That Mediates von Willebrand Factor-Dependent Acute Ischemic Stroke by Promoting Postischemic Thrombo-Inflammation.
Topics: ADAMTS13 Protein; Animals; Blood Platelets; Bone Marrow Transplantation; Carotid Artery Diseases; Chlorides; Disease Models, Animal; Endothelial Cells; Ferric Compounds; Genetic Predisposition to Disease; Infarction, Middle Cerebral Artery; Inflammation; Inflammation Mediators; Lasers; Male; Mesenteric Vascular Occlusion; Mice, Inbred C57BL; Mice, Knockout; Neutrophil Infiltration; Phenotype; Platelet Transfusion; Reperfusion Injury; Signal Transduction; Thrombosis; Time Factors; von Willebrand Factor | 2016 |
Characterization of the Anticoagulant and Antithrombotic Properties of the Sphingosine 1-Phosphate Mimetic FTY720.
Topics: Adenosine Diphosphate; Animals; Anticoagulants; Arteriovenous Shunt, Surgical; Biomimetic Materials; Blood Platelets; Carotid Artery, Common; Chlorides; Disease Models, Animal; Ferric Compounds; Fibrinolytic Agents; Fingolimod Hydrochloride; Humans; Lysophospholipids; Male; Platelet Aggregation; Platelet Function Tests; Rats; Rats, Sprague-Dawley; Receptors, Lysosphingolipid; Sphingosine; Thrombosis; Vena Cava, Inferior | 2017 |
Synthesis and neuroprotective effects of the complex nanoparticles of iron and sapogenin isolated from the defatted seeds of Camellia oleifera.
Topics: Acetylcholine; Animals; Behavior, Animal; Biomarkers; Biphenyl Compounds; Brain; Camellia; Chlorides; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Compounding; Ferric Compounds; Free Radical Scavengers; Injections, Intravenous; Injections, Subcutaneous; Male; Malondialdehyde; Metal Nanoparticles; Mice; Motor Activity; Nerve Degeneration; Neuroprotective Agents; Oxidative Stress; Phytotherapy; Picrates; Plants, Medicinal; Rotenone; Sapogenins; Seeds; Superoxide Dismutase; Tyrosine 3-Monooxygenase | 2017 |
Effectiveness of deferoxamine on ferric chloride-induced epilepsy in rats.
Topics: Animals; Anticonvulsants; Blotting, Western; Brain; Chlorides; Deferoxamine; Disease Models, Animal; Drug Evaluation, Preclinical; Electroencephalography; Epilepsy; Ferric Compounds; Ferritins; Iron; Magnetic Resonance Imaging; Male; Random Allocation; Rats, Sprague-Dawley; Siderophores; Superoxide Dismutase; Transferrin | 2017 |
Store-operated Ca(2+) entry in platelets occurs independently of transient receptor potential (TRP) C1.
Topics: Animals; Blood Coagulation; Blood Platelets; Calcium; Calcium Signaling; Chlorides; Disease Models, Animal; Ferric Compounds; Humans; Membrane Proteins; Mice; Mice, Knockout; Neoplasm Proteins; Platelet Activation; Stromal Interaction Molecule 1; Thrombosis; Time Factors; TRPC Cation Channels | 2008 |
Restoration of plasma von Willebrand factor deficiency is sufficient to correct thrombus formation after gene therapy for severe von Willebrand disease.
Topics: alpha 1-Antitrypsin; Animals; Bleeding Time; Chlorides; Cytomegalovirus; Disease Models, Animal; Factor VIII; Feasibility Studies; Ferric Compounds; Gene Transfer Techniques; Genetic Therapy; Humans; Liver; Mice; Mice, Knockout; Platelet Adhesiveness; Platelet Aggregation; Promoter Regions, Genetic; Severity of Illness Index; Thrombosis; Time Factors; von Willebrand Diseases; von Willebrand Factor | 2008 |
Salsolinol, an endogenous neurotoxin, enhances platelet aggregation and thrombus formation.
Topics: Adrenergic Antagonists; Animals; Blood Platelets; Cell Survival; Chlorides; Cyclic AMP; Disease Models, Animal; Dose-Response Relationship, Drug; Ferric Compounds; Humans; Isoquinolines; Male; Neurotoxins; P-Selectin; Platelet Aggregation; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Serotonin; Thrombosis; Time Factors | 2008 |
Antithrombotic effects due to pharmacological modulation of thrombin-activatable fibrinolysis inhibitor in rats.
Topics: Animals; Bleeding Time; Blood Coagulation Tests; Carboxypeptidase B2; Chlorides; Disease Models, Animal; Dose-Response Relationship, Drug; Ferric Compounds; Fibrinolytic Agents; Injections, Intravenous; Male; Partial Thromboplastin Time; Plant Proteins; Protease Inhibitors; Prothrombin Time; Rats; Rats, Wistar; Thrombosis; Tissue Plasminogen Activator | 2008 |
Characterization of calcium- and integrin-binding protein 1 (CIB1) knockout platelets: potential compensation by CIB family members.
Topics: Animals; Binding Sites; Blood Platelets; Calcium-Binding Proteins; Cells, Cultured; Chlorides; Disease Models, Animal; Ferric Compounds; Hydrophobic and Hydrophilic Interactions; Megakaryocytes; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Molecular; Phenotype; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoprotein IIb; Protein Conformation; Recombinant Proteins; RNA, Messenger; Thrombosis; Time Factors | 2008 |
Studies of free radical generation by neurons in a rat model of cerebral venous sinus thrombosis.
Topics: Animals; Chlorides; Disease Models, Animal; Ferric Compounds; Flow Cytometry; Free Radicals; Male; Neurologic Examination; Neurons; Rats; Rats, Sprague-Dawley; Sinus Thrombosis, Intracranial; Time Factors | 2009 |
Platelet P2Y(12) receptor influences the vessel wall response to arterial injury and thrombosis.
Topics: Animals; Atherosclerosis; Blood Platelets; Bone Marrow Transplantation; Chlorides; Disease Models, Animal; Female; Femoral Artery; Ferric Compounds; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Muscle, Smooth, Vascular; Noxae; P-Selectin; Platelet Aggregation; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Thrombosis; Tunica Intima | 2009 |
Autoantibodies to heat shock protein 60 promote thrombus formation in a murine model of arterial thrombosis.
Topics: Animals; Arterial Occlusive Diseases; Autoantibodies; Carotid Artery Diseases; Chaperonin 60; Chlorides; Disease Models, Animal; Ferric Compounds; Mice; P-Selectin; Regional Blood Flow; Reperfusion; Thrombosis; von Willebrand Factor | 2009 |
A modified ferric tannate method for visualizing a blood vessel and its usage in the study of spinal cord injury.
Topics: Animals; Biomarkers; Blood Vessels; Chlorides; Coloring Agents; Disease Models, Animal; Ferric Compounds; Histocytochemistry; Immunohistochemistry; Male; Nerve Tissue Proteins; Perfusion; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Staining and Labeling; Tannins | 2009 |
Renal and cardiovascular characterization of COX-2 knockdown mice.
Topics: Animals; Blood Pressure; Blood Urea Nitrogen; Cardiovascular System; Cells, Cultured; Chlorides; Cyclooxygenase 1; Cyclooxygenase 2; Cytokines; Dinoprostone; Disease Models, Animal; Endothelial Cells; Epoprostenol; Ferric Compounds; Glomerular Filtration Rate; Heart Rate; Kidney; Macrophages, Peritoneal; Membrane Proteins; Mice; Mice, Knockout; Microscopy, Video; Thrombosis; Thromboxane B2; Time Factors | 2009 |
Radiological and histological changes following cerebral venous sinus thrombosis in a rat model.
Topics: Animals; Brain Edema; Chlorides; Disease Models, Animal; Ferric Compounds; Magnetic Resonance Imaging; Male; Noxae; Rats; Rats, Sprague-Dawley; Sinus Thrombosis, Intracranial; Superior Sagittal Sinus | 2009 |
A ferric chloride induced arterial injury model used as haemostatic effect model.
Topics: Animals; Carotid Artery Diseases; Chlorides; Disease Models, Animal; Dose-Response Relationship, Drug; Factor IX; Factor VIII; Ferric Compounds; Hemophilia A; Hemostasis; Mice; Mice, Knockout; Recombinant Proteins; Thrombosis | 2010 |
Deletion of the p110beta isoform of phosphoinositide 3-kinase in platelets reveals its central role in Akt activation and thrombus formation in vitro and in vivo.
Topics: Animals; Bleeding Time; Blood Platelets; Cell Lineage; Cells, Cultured; Chlorides; Class I Phosphatidylinositol 3-Kinases; Disease Models, Animal; Enzyme Activation; Ferric Compounds; Gene Deletion; Genetic Predisposition to Disease; Isoenzymes; Megakaryocytes; Mice; Mice, Transgenic; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Platelet Aggregation; Thrombosis | 2010 |
Role of coagulation factors in cerebral venous sinus and cerebral microvascular thrombosis.
Topics: Animals; Antigens, CD; Blood Coagulation Factors; Chlorides; Cranial Sinuses; Dextrans; Disease Models, Animal; Endothelial Protein C Receptor; Ferric Compounds; Fluorescein-5-isothiocyanate; Heparin; Intracranial Thrombosis; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Video; Protein C; Receptors, Cell Surface | 2010 |
Vascular protection with less activation evoked by progressive thermal preconditioning in adrenergic receptor-mediated hypertension and tachycardia.
Topics: Animals; Body Temperature; Cardiovascular Physiological Phenomena; Chlorides; Disease Models, Animal; Femoral Artery; Ferric Compounds; Heart Rate; Hemodynamics; Hot Temperature; HSP70 Heat-Shock Proteins; Hypertension; Male; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Tachycardia; Vascular Diseases | 2009 |
The difference in seizure incidences between young and adult rats related to lipid peroxidation after intracortical injection of ferric chloride.
Topics: Age Factors; Animals; Brain; Brain Hemorrhage, Traumatic; Chlorides; Disease Models, Animal; Epilepsy; Ferric Compounds; Incidence; Lipid Peroxidation; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase | 2010 |
Mutation-specific hemostatic variability in mice expressing common type 2B von Willebrand disease substitutions.
Topics: Amino Acid Substitution; Animals; Blood Platelets; Chlorides; Disease Models, Animal; Ferric Compounds; Humans; Integrin alpha2; Mice; Mice, Knockout; Mutation, Missense; Noxae; Platelet Adhesiveness; Thrombocytopenia; Thrombosis; von Willebrand Disease, Type 2; von Willebrand Factor | 2010 |
Optimization, refinement and reduction of murine in vivo experiments to assess therapeutic approaches for haemophilia A.
Topics: Animal Use Alternatives; Animal Welfare; Animals; Arterial Occlusive Diseases; Carotid Artery Diseases; Chlorides; Coagulants; Disease Models, Animal; Female; Ferric Compounds; Hemophilia A; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Regional Blood Flow; Research Design | 2010 |
FIX-Triple, a gain-of-function factor IX variant, improves haemostasis in mouse models without increased risk of thrombosis.
Topics: Animals; Chlorides; Coagulants; Dependovirus; Disease Models, Animal; Dose-Response Relationship, Drug; Factor IX; Ferric Compounds; Genetic Therapy; Genetic Vectors; Hemophilia B; Hemostasis; Humans; Infusions, Intravenous; Laser-Doppler Flowmetry; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mice, Transgenic; Mutation; Recombinant Proteins; Risk Assessment; Thrombelastography; Time Factors; Venous Thrombosis | 2010 |
In vivo models for the evaluation of antithrombotics and thrombolytics.
Topics: Animals; Cardiopulmonary Bypass; Chlorides; Constriction, Pathologic; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Electricity; Female; Ferric Compounds; Fibrinolytic Agents; Foreign Bodies; Hematologic Diseases; Hemostasis; Humans; Lasers; Male; Mice; Models, Genetic; Photochemical Processes; Rabbits; Rats; Stress, Mechanical; Thrombin; Thrombosis | 2010 |
Evaluation of AR-H067637, the active metabolite of the new direct thrombin inhibitor AZD0837, in models of venous and arterial thrombosis and bleeding in anaesthetised rats.
Topics: Amidines; Animals; Antithrombin III; Antithrombins; Azetidines; Blood Coagulation; Chlorides; Dalteparin; Disease Models, Animal; Dose-Response Relationship, Drug; Ferric Compounds; Fibrinolytic Agents; Hemorrhage; Infusions, Intravenous; Male; Partial Thromboplastin Time; Peptide Hydrolases; Prodrugs; Rats; Rats, Sprague-Dawley; Thrombin; Thrombin Time; Thrombosis; Venous Thrombosis | 2010 |
Platelets enhance lymphocyte adhesion and infiltration into arterial thrombus.
Topics: Adult; Animals; Antibodies, Monoclonal; Arterioles; B-Lymphocytes; Blood Platelets; CD40 Ligand; Chlorides; Collagen; Disease Models, Animal; Female; Ferric Compounds; Humans; Killer Cells, Natural; Leukocyte Rolling; Male; Mesentery; Mice; Mice, Inbred C57BL; Middle Aged; P-Selectin; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Stress, Mechanical; T-Lymphocytes; Thrombosis; Time Factors; Young Adult | 2010 |
Deletion of the high-density lipoprotein receptor scavenger receptor BI in mice modulates thrombosis susceptibility and indirectly affects platelet function by elevation of plasma free cholesterol.
Topics: Animals; Arterial Occlusive Diseases; Blood Platelets; Bone Marrow Transplantation; Chlorides; Cholesterol, Dietary; Cholesterol, HDL; Disease Models, Animal; Ferric Compounds; Fibrinogen; Mice; Mice, Knockout; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation; Scavenger Receptors, Class B; Thrombocytopenia; Thrombosis; Time Factors; Up-Regulation | 2011 |
Overexpression of the cell cycle inhibitor p16INK4a promotes a prothrombotic phenotype following vascular injury in mice.
Topics: Animals; Blood Coagulation; Blood Coagulation Tests; Bone Marrow Transplantation; Chlorides; Cyclin-Dependent Kinase Inhibitor p16; Disease Models, Animal; Ferric Compounds; Genotype; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Ligation; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phenotype; Plasminogen Activator Inhibitor 1; Rose Bengal; Time Factors; Up-Regulation; Vascular System Injuries; Venous Thrombosis | 2011 |
Mechanisms underlying FeCl3-induced arterial thrombosis.
Topics: Animals; Anticoagulants; Carotid Arteries; Chlorides; Disease Models, Animal; Ferric Compounds; Mice; Mice, Inbred C57BL; Microscopy, Electron, Scanning; Platelet Aggregation Inhibitors; Thrombosis; Vascular Diseases | 2011 |
Causal relationship between hyperfibrinogenemia, thrombosis, and resistance to thrombolysis in mice.
Topics: Animals; Carotid Artery Thrombosis; Chlorides; Disease Models, Animal; Drug Resistance; Ferric Compounds; Fibrinogen; Fibrinolytic Agents; Humans; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Platelet Aggregation; Risk Factors; Saphenous Vein; Thrombolytic Therapy; Thrombosis | 2011 |
Molecular magnetic resonance imaging allows the detection of activated platelets in a new mouse model of coronary artery thrombosis.
Topics: Analysis of Variance; Animals; Binding Sites; Blood Platelets; Chlorides; Contrast Media; Coronary Thrombosis; Disease Models, Animal; Ferric Compounds; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred C57BL; Platelet Activation; Platelet Adhesiveness; Platelet Glycoprotein GPIIb-IIIa Complex; Random Allocation | 2011 |
Inducible nitric oxide synthase provides protection against injury-induced thrombosis in female mice.
Topics: Analysis of Variance; Animals; Aorta; Blood Coagulation; Cardiomegaly; Carotid Arteries; Carotid Artery Injuries; Chlorides; Disease Models, Animal; Estradiol; Female; Ferric Compounds; Interferon-gamma; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type II; Regional Blood Flow; Sex Factors; Thrombosis; Time Factors | 2011 |
Enzymatic single-chain antibody tagging: a universal approach to targeted molecular imaging and cell homing in cardiovascular disease.
Topics: Aminoacyltransferases; Animals; Bacterial Proteins; Blood Platelets; Cell Movement; Cell Tracking; Chlorides; CHO Cells; Contrast Media; Cricetinae; Cricetulus; Cysteine Endopeptidases; Disease Models, Animal; Ferric Compounds; Flow Cytometry; Green Fluorescent Proteins; Humans; Magnetic Resonance Imaging; Magnetite Nanoparticles; Mice; Mice, Inbred C57BL; Microscopy, Video; Molecular Probe Techniques; Platelet Activation; Recombinant Fusion Proteins; Single-Chain Antibodies; Thrombosis | 2011 |
Essential domains of a disintegrin and metalloprotease with thrombospondin type 1 repeats-13 metalloprotease required for modulation of arterial thrombosis.
Topics: ADAM Proteins; ADAMTS13 Protein; Animals; Antibodies, Monoclonal; Carotid Stenosis; Chlorides; Disease Models, Animal; Dogs; Ferric Compounds; Half-Life; HEK293 Cells; Humans; Kinetics; Mesenteric Vascular Occlusion; Metalloendopeptidases; Mice; Mice, Knockout; Mutagenesis, Site-Directed; Mutation; Protein Structure, Tertiary; Recombinant Proteins; Structure-Activity Relationship; Thrombosis; Transfection; von Willebrand Factor | 2011 |
Towards a standardization of the murine ferric chloride-induced carotid arterial thrombosis model.
Topics: Animals; Blood Flow Velocity; Carotid Artery Thrombosis; Chlorides; Disease Models, Animal; Ferric Compounds; Male; Mice; Mice, Inbred C57BL; Models, Cardiovascular; Societies, Medical | 2011 |
An antithrombotic fucoidan, unlike heparin, does not prolong bleeding time in a murine arterial thrombosis model: a comparative study of Undaria pinnatifida sporophylls and Fucus vesiculosus.
Topics: Animals; Anticoagulants; Bleeding Time; Chlorides; Disease Models, Animal; Ferric Compounds; Fibrinolytic Agents; Fucus; Heparin; Injections, Intravenous; Male; Mice; Mice, Inbred BALB C; Polysaccharides; Thrombosis; Undaria | 2012 |
Mannose-binding lectin-associated serine protease-1 is a significant contributor to coagulation in a murine model of occlusive thrombosis.
Topics: Animals; Blood Coagulation; Carotid Artery Thrombosis; Chlorides; Complement Pathway, Mannose-Binding Lectin; Disease Models, Animal; Ferric Compounds; Humans; Immunity, Innate; Mannose-Binding Lectins; Mannose-Binding Protein-Associated Serine Proteases; Mice; Thrombin | 2012 |
Defective diacylglycerol-induced Ca2+ entry but normal agonist-induced activation responses in TRPC6-deficient mouse platelets.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; C-Reactive Protein; Calcium Channels; Calcium Signaling; Chlorides; Diglycerides; Disease Models, Animal; Ferric Compounds; Gene Expression Regulation; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; ORAI1 Protein; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; RNA, Messenger; Secretory Vesicles; Stromal Interaction Molecule 1; Thrombin; Thrombosis; Time Factors; TRPC Cation Channels; TRPC6 Cation Channel | 2012 |
In vivo monitoring of venous thrombosis in mice.
Topics: Animals; Anticoagulants; Blood Coagulation; Chlorides; Dalteparin; Disease Models, Animal; Ferric Compounds; Ligation; Male; Mice; Mice, Inbred C57BL; Monitoring, Physiologic; Time Factors; Ultrasonography, Doppler, Color; Ultrasonography, Doppler, Pulsed; Vena Cava, Inferior; Venous Thrombosis | 2012 |
Identification of galectin-1 and galectin-3 as novel partners for von Willebrand factor.
Topics: Animals; Cells, Cultured; Chlorides; Disease Models, Animal; Ferric Compounds; Galectin 1; Galectin 3; Human Umbilical Vein Endothelial Cells; Humans; Immunoprecipitation; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Fluorescence; Platelet Adhesiveness; Protein Binding; Protein Interaction Domains and Motifs; Protein Interaction Mapping; Thrombosis; Time Factors; von Willebrand Factor | 2012 |
Reduction of thrombus size in murine models of thrombosis following administration of recombinant α1-proteinase inhibitor mutant proteins.
Topics: alpha 1-Antitrypsin; Animals; Antithrombins; Carotid Artery Injuries; Chlorides; Disease Models, Animal; Dose-Response Relationship, Drug; Endotoxemia; Endotoxins; Factor Xa; Factor Xa Inhibitors; Factor XIa; Factor XIIa; Ferric Compounds; Fibrinogen; Fibrinolytic Agents; Hemorrhage; Injections, Intravenous; Kinetics; Leukocyte Elastase; Mice; Mutation; NG-Nitroarginine Methyl Ester; Recombinant Fusion Proteins; Thrombin; Thrombosis | 2012 |
Use of a mouse model to elucidate the phenotypic effects of the von Willebrand factor cleavage mutants, Y1605A/M1606A and R1597W.
Topics: ADAMTS13 Protein; Animals; Blood Coagulation; Blotting, Western; Chlorides; Disease Models, Animal; Ferric Compounds; Gene Transfer Techniques; Genotype; HEK293 Cells; Humans; Infusions, Intravenous; Injections, Intravenous; Metalloendopeptidases; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Weight; Mutagenesis, Site-Directed; Mutation; Phenotype; Platelet Activation; Protein Multimerization; Recombinant Proteins; Thrombosis; Time Factors; Transfection; von Willebrand Diseases; von Willebrand Factor | 2012 |
Effects of plasma kallikrein deficiency on haemostasis and thrombosis in mice: murine ortholog of the Fletcher trait.
Topics: Animals; Bleeding Time; Chlorides; Disease Models, Animal; Ferric Compounds; Hemorrhage; Hemostasis; Heterozygote; Mice; Mice, Knockout; Oligonucleotides, Antisense; Partial Thromboplastin Time; Phenotype; Plasma Kallikrein; Prekallikrein; Thrombosis; Time Factors; Venous Thrombosis | 2012 |
The mouse dorsal skinfold chamber as a model for the study of thrombolysis by intravital microscopy.
Topics: Animals; Chlorides; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Ferric Compounds; Fibrinolysis; Fibrinolytic Agents; Hemorrhage; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Fluorescence; Plasminogen Activator Inhibitor 1; Recombinant Proteins; Skin; Thrombolytic Therapy; Thrombosis; Time Factors; Tissue Plasminogen Activator | 2012 |
Algal fucoidan, unlike heparin, has thrombolytic activity in a murine arterial thrombosis model.
Topics: Animals; Carotid Arteries; Chlorides; Coronary Thrombosis; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Ferric Compounds; Fibrinolytic Agents; Heparin; Injections, Intravenous; Mice; Mice, Inbred BALB C; Polysaccharides; Thrombolytic Therapy; Tissue Plasminogen Activator; Undaria | 2012 |
Cationic derivative of dextran reverses anticoagulant activity of unfractionated heparin in animal models of arterial and venous thrombosis.
Topics: Animals; Anticoagulants; Bleeding Time; Blood Coagulation; Chlorides; Dextrans; Disease Models, Animal; Ferric Compounds; Heparin; Heparin Antagonists; Male; Mice; Partial Thromboplastin Time; Platelet Aggregation; Protamines; Rats; Rats, Wistar; Thrombosis | 2012 |
A novel model of atherosclerosis in rabbits using injury to arterial walls induced by ferric chloride as evaluated by optical coherence tomography as well as intravascular ultrasound and histology.
Topics: Animals; Arteries; Atherosclerosis; Chlorides; Cholesterol, Dietary; Disease Models, Animal; Ferric Compounds; Immunohistochemistry; Lipoproteins; Male; Rabbits; Reproducibility of Results; Tomography, Optical Coherence; Ultrasonography, Interventional | 2012 |
Molecular imaging of fibrin deposition in deep vein thrombosis using fibrin-targeted near-infrared fluorescence.
Topics: Animals; Chlorides; Disease Models, Animal; Femoral Vein; Ferric Compounds; Fibrin; Fluorescent Dyes; Half-Life; Humans; Indoles; Injections, Intravenous; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Microscopy, Fluorescence; Molecular Imaging; Oligopeptides; Phlebography; Radionuclide Imaging; Spectroscopy, Near-Infrared; Tissue Distribution; Tomography, X-Ray Computed; Venous Thrombosis | 2012 |
Platelets, glycoprotein Ib-IX, and von Willebrand factor are required for FeCl(3)-induced occlusive thrombus formation in the inferior vena cava of mice.
Topics: Animals; Blood Platelets; Chlorides; Disease Models, Animal; Ferric Compounds; Mice; Platelet Glycoprotein GPIb-IX Complex; Protein Binding; Vena Cava, Inferior; Venous Thrombosis; von Willebrand Factor | 2013 |
ADAMTS13 exerts a thrombolytic effect in microcirculation.
Topics: ADAM Proteins; ADAMTS13 Protein; Animals; Chlorides; Computer Systems; Disease Models, Animal; Drug Evaluation, Preclinical; Ferric Compounds; Fibrinolytic Agents; Hemorrhage; Humans; Male; Mice; Mice, Inbred C57BL; Microcirculation; Microscopy; Recombinant Proteins; Skin Window Technique; Thrombolytic Therapy; Tissue Plasminogen Activator; Venous Thrombosis; Venules | 2012 |
Lufaxin, a novel factor Xa inhibitor from the salivary gland of the sand fly Lutzomyia longipalpis blocks protease-activated receptor 2 activation and inhibits inflammation and thrombosis in vivo.
Topics: Amino Acid Sequence; Animals; Anti-Inflammatory Agents; Blood Coagulation; Calorimetry; Cell Line, Tumor; Chlorides; Cloning, Molecular; Disease Models, Animal; Dose-Response Relationship, Drug; Factor Xa; Factor Xa Inhibitors; Female; Ferric Compounds; Fibrinolytic Agents; HEK293 Cells; Humans; Inflammation; Insect Proteins; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Molecular Weight; Partial Thromboplastin Time; Protein Binding; Prothrombin Time; Psychodidae; Rats; Receptor, PAR-2; Recombinant Proteins; Salivary Glands; Surface Plasmon Resonance; Thromboplastin; Thrombosis; Time Factors | 2012 |
Increased platelet activation and thrombosis in transgenic mice expressing constitutively active P2Y12.
Topics: Adenosine Monophosphate; Animals; Bleeding Time; Blood Platelets; Chlorides; Cyclic AMP; Disease Models, Animal; Drug Inverse Agonism; Ferric Compounds; Fibrinolytic Agents; Genotype; Mice; Mice, Transgenic; Phenotype; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Proto-Oncogene Proteins c-akt; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Thrombosis | 2012 |
A murine model to characterize the antithrombotic effect of molecules targeting human von Willebrand factor.
Topics: ADAMTS13 Protein; Animals; Antibodies, Monoclonal; Chlorides; Collagen; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Ferric Compounds; Fibrinolytic Agents; Hemorrhage; Humans; Metalloendopeptidases; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutagenesis, Site-Directed; Mutation; Platelet Adhesiveness; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombosis; von Willebrand Factor | 2012 |
Inflammation modulates murine venous thrombosis resolution in vivo: assessment by multimodal fluorescence molecular imaging.
Topics: Animals; Biomarkers; Chlorides; Dextrans; Disease Models, Animal; Femoral Vein; Ferric Compounds; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Inflammation; Jugular Veins; Macrophages; Male; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Microscopy, Fluorescence; Molecular Imaging; Phlebography; Prognosis; Reproducibility of Results; Saphenous Vein; Severity of Illness Index; Time Factors; Tomography, X-Ray Computed; Venous Thrombosis | 2012 |
Ferrous ferric chloride downregulates the inflammatory response to Rhodococcus aurantiacus infection in mice.
Topics: Actinomycetales Infections; Adaptive Immunity; Animals; Anti-Inflammatory Agents; Beverages; Chlorides; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Female; Ferric Compounds; Ferrous Compounds; Gene Expression; Granuloma; Heme Oxygenase-1; Inflammation; Interleukin-10; Interleukin-6; Liver; Macrophages; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Rhodococcus; RNA, Messenger; Tumor Necrosis Factor-alpha | 2012 |
Timosaponin-BII inhibits the up-regulation of BACE1 induced by ferric chloride in rat retina.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Anemarrhena; Animals; Antioxidants; Chlorides; Disease Models, Animal; Drugs, Chinese Herbal; Ferric Compounds; Male; Malondialdehyde; Oxidative Stress; Partial Thromboplastin Time; Phytotherapy; Rats; Rats, Sprague-Dawley; Retina; Rhizome; Saponins; Steroids; Up-Regulation | 2012 |
In vitro and in vivo evaluation of the effect of elevated factor VIII on the thrombogenic process.
Topics: Animals; Antithrombin III; Blood Coagulation; Chlorides; Disease Models, Animal; Factor VIII; Ferric Compounds; Hemophilia A; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptide Hydrolases; Thrombelastography; Thrombosis; Time Factors; Up-Regulation; Vascular System Injuries | 2013 |
GDF-15 prevents platelet integrin activation and thrombus formation.
Topics: Animals; Bleeding Time; Blood Platelets; Chlorides; Collagen; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Enzyme Activation; Ferric Compounds; Flow Cytometry; Growth Differentiation Factor 15; Hemostasis; Humans; Integrin beta1; Integrin beta3; Integrins; Mice; Mice, Inbred C57BL; Mice, Knockout; P-Selectin; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pulmonary Embolism; rap1 GTP-Binding Proteins; Recombinant Proteins; Thrombosis; Time Factors | 2013 |
Red blood cells mediate the onset of thrombosis in the ferric chloride murine model.
Topics: Animals; Cells, Cultured; Chlorides; Disease Models, Animal; Erythrocyte Aggregation; Erythrocytes; Ferric Compounds; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Platelet Adhesiveness; Receptors, Cell Surface; Thrombosis; von Willebrand Factor | 2013 |
Different mechanisms of increased luminal stenosis after arterial injury in mice deficient for urokinase- or tissue-type plasminogen activator.
Topics: Animals; Carotid Arteries; Carotid Stenosis; Cell Count; Chlorides; Disease Models, Animal; Ferric Compounds; Hemodynamics; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tissue Plasminogen Activator; Tunica Intima; Tunica Media; Urokinase-Type Plasminogen Activator; Vascular Patency; Wound Healing | 2002 |
Dopamine release rather than content in the caudate putamen is associated with behavioral changes in the iron rat model of Parkinson's disease.
Topics: Animals; Apomorphine; Behavior, Animal; Caudate Nucleus; Chlorides; Deferoxamine; Disease Models, Animal; Dopamine; Drug Administration Routes; Female; Ferric Compounds; Iron; Iron Chelating Agents; Parkinsonian Disorders; Putamen; Rats; Rats, Sprague-Dawley | 2003 |
Effect of zonisamide on molecular regulation of glutamate and GABA transporter proteins during epileptogenesis in rats with hippocampal seizures.
Topics: Amino Acid Transport System X-AG; Amygdala; Animals; Anticonvulsants; Blotting, Western; Carrier Proteins; Chlorides; Chronic Disease; Disease Models, Animal; Epilepsy; Ferric Compounds; Frontal Lobe; GABA Plasma Membrane Transport Proteins; Hippocampus; Isoxazoles; Male; Membrane Proteins; Membrane Transport Proteins; Organic Anion Transporters; Rats; Rats, Wistar; Zonisamide | 2003 |
[Guinea pig model of basilar artery thrombosis induced by ferric chloride].
Topics: Animals; Basilar Artery; Chlorides; Cochlea; Disease Models, Animal; Ferric Compounds; Guinea Pigs; Intracranial Thrombosis; Male; Microcirculation | 2003 |
Cause-effect relation between hyperfibrinogenemia and vascular disease.
Topics: Animals; Carotid Arteries; Chlorides; Cross-Linking Reagents; Dimerization; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Ferric Compounds; Fibrinogen; Mice; Mice, Transgenic; Protein Binding; Thrombin; Thrombosis; Vascular Diseases | 2004 |
Leptin promotes vascular remodeling and neointimal growth in mice.
Topics: Animals; Aorta; Arteriosclerosis; Carotid Arteries; Chlorides; Diet, Atherogenic; Dietary Fats; Disease Models, Animal; Ferric Compounds; Gene Expression Regulation; Hyperplasia; Leptin; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Obesity; Receptors, Cell Surface; Receptors, Leptin; Recombinant Proteins; RNA, Messenger; Tunica Intima | 2004 |
Differential effects of sodium nitroprusside and hydralazine in a rat model of topical FeCl3-induced carotid artery thrombosis.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Carotid Artery Thrombosis; Chlorides; Disease Models, Animal; Ferric Compounds; Heart Rate; Hydralazine; Kinetics; Male; Nitroprusside; Platelet Aggregation; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 2003 |
Lipoic acid pretreatment attenuates ferric chloride-induced seizures in the rat.
Topics: Animals; Antioxidants; Chlorides; Disease Models, Animal; Electroencephalography; Ferric Compounds; Male; Rats; Rats, Sprague-Dawley; Reaction Time; Seizures; Thioctic Acid | 2004 |
The combination of modified antioxidant enzymes for anti-thrombotic protection of the vascular wall: the significance of covalent connection of superoxide dismutase and catalase activities.
Topics: Animals; Antioxidants; Catalase; Chlorides; Chondroitin Sulfates; Disease Models, Animal; Ferric Compounds; Injections, Intravenous; Male; Rats; Structure-Activity Relationship; Superoxide Dismutase; Thrombosis | 2004 |
An optimized murine model of ferric chloride-induced arterial thrombosis for thrombosis research.
Topics: Animals; Arterial Occlusive Diseases; Carotid Artery Diseases; Chlorides; Clopidogrel; Disease Models, Animal; Dose-Response Relationship, Drug; Ferric Compounds; Heparin; Kinetics; Mice; Regional Blood Flow; Research; Thrombosis; Ticlopidine | 2005 |
Is heparin treatment the optimal management for cerebral venous thrombosis? Effect of abciximab, recombinant tissue plasminogen activator, and enoxaparin in experimentally induced superior sagittal sinus thrombosis.
Topics: Abciximab; Angiography; Animals; Antibodies, Monoclonal; Anticoagulants; Blood Platelets; Chlorides; Disease Models, Animal; Edema; Enoxaparin; Ferric Compounds; Heparin; Humans; Hydrogen-Ion Concentration; Immunoglobulin Fab Fragments; Intracranial Embolism and Thrombosis; Magnetic Resonance Imaging; Male; Rats; Recombinant Proteins; Sagittal Sinus Thrombosis; Thrombolytic Therapy; Time Factors; Tissue Plasminogen Activator; Treatment Outcome; Venous Thrombosis | 2005 |
Evaluation of two experimental venous thrombosis models in the rat.
Topics: Animals; Blood Coagulation Tests; Chlorides; Disease Models, Animal; Female; Ferric Compounds; Hemostasis; Male; Nadroparin; Rats; Rats, Wistar; Regression Analysis; Sensitivity and Specificity; Thromboplastin; Thrombosis; Venous Thrombosis | 2005 |
Characterization of an original model of myocardial infarction provoked by coronary artery thrombosis induced by ferric chloride in pig.
Topics: Adenosine Triphosphate; Animals; Chlorides; Coronary Circulation; Coronary Thrombosis; Disease Models, Animal; Female; Ferric Compounds; Hemodynamics; In Vitro Techniques; Male; Myocardial Infarction; Myocytes, Cardiac; Platelet Aggregation; Platelet Count; Sus scrofa; Troponin T | 2005 |
A new model of reversible sinus sagittalis superior thrombosis in the rat: magnetic resonance imaging changes.
Topics: Animals; Behavior, Animal; Blood Glucose; Blood Pressure; Brain Edema; Cerebrovascular Circulation; Chlorides; Disease Models, Animal; Ferric Compounds; Heart Rate; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Male; Motor Activity; Rats; Reproducibility of Results; Rotarod Performance Test; Sagittal Sinus Thrombosis; Time Factors | 2005 |
Nanoparticle-induced platelet aggregation and vascular thrombosis.
Topics: Animals; Blood Platelets; Carotid Artery Thrombosis; Chlorides; Disease Models, Animal; Dose-Response Relationship, Drug; Epoprostenol; Ferric Compounds; Humans; Microscopy, Electron, Transmission; Microscopy, Phase-Contrast; Nanostructures; Nanotechnology; Nanotubes, Carbon; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Rats; Rats, Inbred WKY; S-Nitrosoglutathione; Signal Transduction | 2005 |
A murine model of deep vein thrombosis: characterization and validation in transgenic mice.
Topics: Animals; Anticoagulants; Chlorides; Coronary Artery Disease; Coronary Vessels; Disease Models, Animal; Drug Evaluation, Preclinical; Electric Stimulation; Factor V; Femoral Vein; Ferric Compounds; Heparin; Mice; Mice, Inbred C57BL; Mice, Transgenic; Point Mutation; Reproducibility of Results; Venous Thrombosis | 2005 |
Murine model of ferric chloride-induced vena cava thrombosis: evidence for effect of potato carboxypeptidase inhibitor.
Topics: Animals; Carboxypeptidase B2; Carboxypeptidases; Carotid Artery Thrombosis; Chlorides; Disease Models, Animal; Ferric Compounds; Fibrinolytic Agents; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Plant Proteins; Protease Inhibitors; Solanum tuberosum; Thrombolytic Therapy; Venae Cavae; Venous Thrombosis | 2006 |
7beta-hydroxycholesterol reduces the extent of reactive gliosis caused by iron deposition in the hippocampus but does not attenuate the iron-induced seizures in rats.
Topics: Action Potentials; Animals; Anti-Inflammatory Agents; Astrocytes; Brain Injuries; Chlorides; Convulsants; Disease Models, Animal; Down-Regulation; Epilepsy; Epilepsy, Temporal Lobe; Ferric Compounds; Glial Fibrillary Acidic Protein; Gliosis; Hippocampus; Hydroxycholesterols; Iron; Iron Metabolism Disorders; Neuroprotective Agents; Rats; Reaction Time; Synaptophysin; Up-Regulation | 2006 |
Increased venous versus arterial thrombosis in the Factor V Leiden mouse.
Topics: Amino Acid Substitution; Animals; Arginine; Arterial Occlusive Diseases; Arteries; Chlorides; Disease Models, Animal; Factor V; Ferric Compounds; Gene Frequency; Glutamine; Homozygote; Mice; Mice, Inbred C57BL; Mutation; Thrombosis; Venous Thrombosis | 2007 |
Quantification of platelet composition in experimental venous thrombosis by real-time polymerase chain reaction.
Topics: Animals; Blood Platelets; Chemokine CCL2; Chlorides; Disease Models, Animal; Ferric Compounds; Gene Expression; Interleukin-1beta; Male; Microscopy, Electron; Nitric Oxide Synthase Type II; P-Selectin; Platelet Factor 4; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Saline Solution, Hypertonic; Thrombin; Thrombosis; Venae Cavae; Venous Thrombosis | 2007 |
Central heme oxygenase-carbon monoxide pathway participates in the lipopolysaccharide-induced tolerance in rats.
Topics: Animals; Biliverdine; Body Temperature; Carbon Monoxide; Chlorides; Cyclic GMP; Disease Models, Animal; Down-Regulation; Drug Tolerance; Endotoxins; Enzyme Inhibitors; Ferric Compounds; Fever; Guanylate Cyclase; Heme Oxygenase (Decyclizing); Infections; Inflammation Mediators; Injections, Intraperitoneal; Iron; Lipopolysaccharides; Male; Rats; Rats, Wistar; Signal Transduction | 2006 |
Effects of factor XI deficiency on ferric chloride-induced vena cava thrombosis in mice.
Topics: Animals; Chlorides; Disease Models, Animal; Factor XI Deficiency; Ferric Compounds; Fibrinolysis; Fibrinolytic Agents; Mice; Venae Cavae; Venous Thrombosis | 2006 |
Distinct antithrombotic consequences of platelet glycoprotein Ibalpha and VI deficiency in a mouse model of arterial thrombosis.
Topics: Animals; Arterial Occlusive Diseases; Carotid Artery Thrombosis; Chlorides; Disease Models, Animal; Ferric Compounds; Mice; Mice, Knockout; Platelet Glycoprotein GPIb-IX Complex; Platelet Membrane Glycoproteins | 2006 |
Deficiency in thrombin-activatable fibrinolysis inhibitor (TAFI) protected mice from ferric chloride-induced vena cava thrombosis.
Topics: Animals; Bleeding Time; Carboxypeptidase B2; Carotid Artery Diseases; Chlorides; Coagulants; Disease Models, Animal; Female; Ferric Compounds; Male; Mice; Mice, Knockout; Plant Proteins; Protease Inhibitors; Thrombelastography; Venae Cavae; Venous Thrombosis | 2007 |
Genetic strain differences in platelet aggregation and thrombus formation of laboratory rats.
Topics: Adenosine Diphosphate; Animals; Arteriovenous Shunt, Surgical; Bleeding Time; Blood Platelets; Chlorides; Collagen; Disease Models, Animal; Drug Evaluation, Preclinical; Ferric Compounds; Fibrinolytic Agents; Genetic Variation; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Inbred ACI; Rats, Inbred BN; Rats, Inbred F344; Rats, Inbred Lew; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Thrombin; Species Specificity; Thrombosis | 2007 |
Functional role for redox in the epileptogenesis: molecular regulation of glutamate in the hippocampus of FeCl3-induced limbic epilepsy model.
Topics: Animals; Behavior, Animal; Chlorides; Disease Models, Animal; Epilepsy; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Ferric Compounds; Gene Expression Regulation; Glutamic Acid; Hippocampus; Male; Microdialysis; Oxidation-Reduction; Rats; Rats, Wistar; Statistics, Nonparametric | 2007 |
In vivo EPR estimation of bilateral hippocampal antioxidant ability of rats with epileptogenesis induced by amygdalar FeCl3 microinjection.
Topics: Amygdala; Animals; Antioxidants; Chlorides; Chronic Disease; Disease Models, Animal; Electrodes, Implanted; Electron Spin Resonance Spectroscopy; Epilepsy; Ferric Compounds; Free Radicals; Functional Laterality; Hippocampus; Limbic System; Male; Microinjections; Neural Pathways; Neurons; Nitrogen Oxides; Noxae; Rats; Rats, Wistar; Seizures | 2007 |
Hyperglycemia accelerates arterial thrombus formation and attenuates the antithrombotic response to endotoxin in mice.
Topics: Animals; Blood Coagulation; Carotid Artery Thrombosis; Chlorides; Diabetes Mellitus, Experimental; Disease Models, Animal; Endotoxins; Female; Ferric Compounds; Fibrinolytic Agents; Hyperglycemia; Mice; Mice, Inbred C57BL; Streptozocin; Thrombin; Thrombin Time; Thrombophlebitis | 2007 |
GSK3beta is a negative regulator of platelet function and thrombosis.
Topics: Animals; Blood Platelets; Carotid Artery Injuries; Chlorides; Disease Models, Animal; Enzyme Inhibitors; Ferric Compounds; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Mice; Mice, Knockout; Noxae; Phosphorylation; Platelet Aggregation; Proto-Oncogene Proteins c-akt; Thrombosis | 2008 |
Inhibitory role of Acorus calamus in ferric chloride-induced epileptogenesis in rat.
Topics: Acorus; Animals; Behavior, Animal; Catalase; Chlorides; Disease Models, Animal; Electroencephalography; Epilepsy; Ferric Compounds; Lipid Peroxidation; Male; Neuroprotective Agents; Noxae; Plant Extracts; Rats; Rats, Sprague-Dawley; Rhizome; Somatosensory Cortex; Superoxide Dismutase; Tremor | 2007 |
Cigarette smoke exposure promotes arterial thrombosis and vessel remodeling after vascular injury in apolipoprotein E-deficient mice.
Topics: Actins; Animals; Apolipoproteins E; Apoptosis; Carotid Artery Diseases; Cell Proliferation; Cells, Cultured; Chlorides; Disease Models, Animal; Dose-Response Relationship, Drug; Ferric Compounds; Humans; Male; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Smoke; Smoking; Thrombosis; Time Factors; Vascular Patency | 2008 |
Lipopolysaccharide augments venous and arterial thrombosis in the mouse.
Topics: Animals; Arteries; Carotid Artery Thrombosis; Chlorides; Disease Models, Animal; Dose-Response Relationship, Drug; Ferric Compounds; Fibrinolytic Agents; Interleukin-1beta; Lipopolysaccharides; Mice; Mice, Inbred C57BL; RNA, Messenger; Thrombosis; Time Factors; Tumor Necrosis Factor-alpha; Veins; Venae Cavae; Venous Thrombosis | 2008 |
Experimental chronic epilepsy in rats: a screening method for antiepileptic drugs.
Topics: Animals; Anticonvulsants; Chlorides; Chronic Disease; Clonazepam; Diazepam; Disease Models, Animal; Drug Evaluation, Preclinical; Electroencephalography; Ferric Compounds; Male; Rats; Rats, Inbred Strains; Seizures | 1983 |
Synthesis and comparison of tripeptidylfluoroalkane thrombin inhibitors.
Topics: Amino Acid Sequence; Animals; Anticoagulants; Antithrombins; Blood Platelets; Carotid Artery Thrombosis; Chlorides; Disease Models, Animal; Ferric Compounds; Fluorocarbons; Indicators and Reagents; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Oligopeptides; Rats | 1995 |
Inflammatory and phagocytic response to experimental Campylobacter jejuni infection in mice.
Topics: Animals; Bacteremia; Campylobacter Infections; Campylobacter jejuni; Chlorides; Disease Models, Animal; Ferric Compounds; Immunity, Cellular; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Peritonitis; Phagocytosis; Species Specificity | 1994 |
(+-)-1-Amino-1,3-cyclopentane-trans-dicarboxylic acid (trans-ACPD) induced inositol triphosphoric acid formation in the brain of iron-induced epileptic rats and epileptic El mice.
Topics: Animals; Brain; Chlorides; Cycloleucine; Disease Models, Animal; Epilepsy; Ferric Compounds; Inositol 1,4,5-Trisphosphate; Male; Mice; Neurotoxins; Rats; Rats, Sprague-Dawley | 1994 |
Synergistic inhibition of the calcification of glutaraldehyde pretreated bovine pericardium in a rat subdermal model by FeCl3 and ethanehydroxydiphosphonate: preincubation and polymeric controlled release studies.
Topics: Animals; Bioprosthesis; Calcinosis; Cattle; Chlorides; Delayed-Action Preparations; Disease Models, Animal; Drug Synergism; Etidronic Acid; Ferric Compounds; Glutaral; Heart Valve Prosthesis; Male; Pericardium; Polymers; Prosthesis Failure; Protamines; Rats; Rats, Sprague-Dawley | 1993 |
[A rat middle cerebral artery thrombosis model for evaluation of thrombolytic and antithrombotic agents].
Topics: Animals; Aspirin; Chlorides; Disease Models, Animal; Ferric Compounds; Fibrinolytic Agents; Intracranial Embolism and Thrombosis; Male; Rats; Rats, Wistar; Urokinase-Type Plasminogen Activator | 1995 |
Interactions between tissue uptake of lead and iron in normal and iron-deficient rats during development.
Topics: Aging; Animals; Binding Sites; Body Weight; Brain; Chlorides; Disease Models, Animal; Female; Ferric Compounds; Injections, Intravenous; Intestinal Absorption; Iron; Iron Deficiencies; Isotope Labeling; Kidney; Lead; Lead Poisoning; Liver; Nutritional Status; Pregnancy; Rats; Rats, Wistar; Tissue Distribution; Transferrin | 1996 |
Reduction in nitric oxide synthase activity with development of an epileptogenic focus induced by ferric chloride in the rat brain.
Topics: Animals; Brain; Chlorides; Disease Models, Animal; Epilepsy; Ferric Compounds; Male; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley | 1996 |
Synergistic inhibition of calcification of porcine aortic root with preincubation in FeCl3 and alpha-amino oleic acid in a rat subdermal model.
Topics: Animals; Aorta; Calcinosis; Chlorides; Disease Models, Animal; Equipment Failure; Ferric Compounds; Heart Valve Prosthesis; Oleic Acids; Rats; Swine | 1997 |
A Streptococcus pneumoniae pathogenicity island encoding an ABC transporter involved in iron uptake and virulence.
Topics: Animals; ATP-Binding Cassette Transporters; Chlorides; Disease Models, Animal; Ferric Compounds; Genes, Bacterial; Humans; Iron; Mice; Pneumococcal Infections; Sequence Analysis, DNA; Streptococcus pneumoniae; Streptonigrin; Virulence | 2001 |
Chronic L-DOPA administration is not toxic to the remaining dopaminergic nigrostriatal neurons, but instead may promote their functional recovery, in rats with partial 6-OHDA or FeCl(3) nigrostriatal lesions.
Topics: Adrenergic Agents; Analysis of Variance; Animals; Antiparkinson Agents; Benserazide; Chlorides; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Ferric Compounds; Immunoenzyme Techniques; Levodopa; Male; Neostriatum; Nerve Net; Neurons; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tyrosine 3-Monooxygenase | 2001 |
Variable protection of beta 3-integrin--deficient mice from thrombosis initiated by different mechanisms.
Topics: Animals; Antibodies, Monoclonal; Antigens, CD; Blood Platelets; Carotid Artery Thrombosis; Chlorides; Disease Models, Animal; Female; Ferric Compounds; Fibrin; Immunohistochemistry; Integrin beta3; Male; Mice; Mice, Knockout; Microcirculation; Microscopy, Electron; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoproteins; Receptors, Vitronectin; Thrombosis | 2001 |
Magnesium inhibits arterial thrombi after vascular injury in rat: in vivo impairment of coagulation.
Topics: Animals; Blood Coagulation Tests; Carotid Arteries; Chlorides; Disease Models, Animal; Dose-Response Relationship, Drug; Ferric Compounds; Hemostasis; Magnesium Sulfate; Male; Platelet Aggregation; Rats; Rats, Sprague-Dawley; Thrombosis; Time Factors | 2001 |
Rat model of arterial thrombosis induced by ferric chloride.
Topics: Animals; Body Temperature; Carotid Artery Thrombosis; Chlorides; Disease Models, Animal; Ferric Compounds; Male; Microscopy, Electron, Scanning; Rats; Rats, Inbred Strains | 1990 |