ferric chloride has been researched along with Blood Clot in 185 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (3.24) | 18.2507 |
| 2000's | 64 (34.59) | 29.6817 |
| 2010's | 103 (55.68) | 24.3611 |
| 2020's | 12 (6.49) | 2.80 |
| Authors | Studies |
|---|---|
| Ibi, M; Kami, D; Kubota, H; Matoba, S; Miyawaki, D; Motoyama, S; Ogata, T; Saburi, M; Sugimoto, T; Wada, N; Wakana, N; Yamada, H | 1 |
| Gul, H; Jabeen, Q | 1 |
| Ammollo, CT; Argenziano, M; Capolla, S; Cavalli, R; Colucci, M; Di Leonardo, V; Durigutto, P; Macor, P; Marchbank, K; Meroni, P; Semeraro, F; Smith-Jackson, K; Tedesco, F; Tolva, VS | 1 |
| Alfar, HR; Aronova, M; Joshi, S; Leapman, RD; Lykins, J; Pokrovskaya, I; Prakhya, KS; Smith, AN; Storrie, B; Whiteheart, SW; Zhang, M | 1 |
| Cheng, XW; Huang, Z; Inoue, A; Jin, X; Kuzuya, M; Meng, X; Piao, L; Shi, GP; Wan, Y; Wang, H; Xu, S; Yue, X | 1 |
| Cheng, Z; Hu, Y; Ming, Z; Zhou, X; Zhu, R | 1 |
| Brenner, JS; Glassman, PM; Marcos-Contreras, OA; Muzykantov, VR; Myerson, JW; Nong, J | 1 |
| Abdelfadiel, EI; Afosah, DK; Al-Horani, RA; Brophy, DF; Desai, UR; Martin, EJ; Mohammed, B; Morla, S; Sakagami, M; Sistla, JC | 1 |
| Kim, JY; Kim, KJ; Kim, MS; Seok, PR; Shin, JH | 1 |
| Gong, X; Gu, Q; Ji, Y; Li, CJ; Li, D; Liu, Y; Lu, Y; Mei, L; Yang, F; Yang, M; Ye, S | 1 |
| Abdelhafez, MM; Angelillo-Scherrer, A; Cook, KE; Cooke, A; Demarest, CT; Deyle, K; Gonschorek, P; Heinis, C; Kong, XD; Lamers, C; Middendorp, SJ; Prince, R; Rieben, R; Roberts, K; Umei, N; Wilbs, J | 1 |
| Gui, S; Li, P; Lin, B; Tang, P; Wu, Z; Yang, W; Ye, Y; Zhan, Y | 1 |
| Aburima, A; Berger, M; Febbraio, M; Naseem, KM; Poole, AW; Spurgeon, BEJ; Webb, BA; Wraith, KS | 1 |
| Bonda, TA; Karolczak, K; Kramkowski, K; Polak, D; Przygodzki, T; Talar, M; Watala, C; Wojkowska, DW; Wolska, N | 1 |
| Bem, D; Byrne, M; Lordkipanidzé, M; Mazharian, A; Meyaard, L; Patel, P; Raslan, Z; Senis, YA; Smith, CW; Thomas, SG; Watson, SP | 1 |
| Gwon, S; Hwang, DW; Jeon, J; Kang, C; Kang, PM; Lee, D; Park, SC; Song, C | 1 |
| Ali, C; Denis, CV; Diamond, SL; Gakuba, C; Gauberti, M; Herbig, BA; Lenting, PJ; Martinez de Lizarrondo, S; Repessé, Y; Touzé, E; Vivien, D | 1 |
| Jin, K; Ma, D; Ma, J; Xiao, J; Yang, J | 1 |
| Chang, CH; Chung, CH; Hsu, CC; Huang, TF; Peng, HC; Tsai, CC; Tseng, YJ; Tu, YS | 1 |
| Chang, L; Ding, Z; Hu, L; Kunapuli, SP; Luo, X; Qi, Z; Wang, Y; Yan, H; Yan, Y; Ye, H; Zhai, L; Zhang, S; Zhang, Y | 1 |
| Andreakos, E; Angelidou, I; Arampatzioglou, A; Arelaki, S; Bochenek, M; Chrysanthopoulou, A; Couladouros, EA; Galani, IE; Kambas, K; Konstantinides, S; Mitroulis, I; Mitsios, A; Ritis, K; Schäfer, K; Skendros, P; Stakos, D; Vidali, V | 1 |
| Fan, Q; Fu, C; Li, B; Ma, G; Yao, Y | 1 |
| Adler, K; Borst, O; Brandl, R; Degen, H; Fassbender, J; Gawaz, M; Göbel, S; Jamasbi, J; Lorenz, R; Mojica Munoz, AK; Münch, G; Siess, W; Ungerer, M; Walker, B; Ziegler, M | 1 |
| Chen, CH; Fu, WM; Gau, SS; Hsu, CC; Huang, SW; Huang, TF; Liao, HM; Liou, HC; Lu, DH; Tu, HJ | 1 |
| Cai, Y; Chen, X; Hu, H; Hu, M; Hu, X; Ke, Y; Liu, Y; Luo, D; Wang, S; Wang, Y; Yang, Z; Yue, M; Zhou, Y | 1 |
| Chandraratne, S; Ehrlich, A; Hoti, Q; Konrad, I; Legate, KR; Lorenz, M; Massberg, S; Novotny, J; Oberdieck, P; Pelisek, J; Philippi, V; Pircher, J; Schubert, I; Schulz, C; Stark, K; Titova, A; Urtz, N; von Brühl, ML; Weinberger, T | 1 |
| Aggarwal, H; Barthwal, MK; Bihan, D; Dhankani, P; Dikshit, DK; Dikshit, M; Farndale, RW; Kumar, S; Misra, A; Pandey, CP; Prakash, P; Pugh, N | 1 |
| Bhakta, V; Eltringham-Smith, LJ; Sheffield, WP | 1 |
| Ahlstedt, S; Andersen, JF; Assumpção, TC; Francischetti, IMB; Kotsyfakis, M; Lukszo, J; Ma, D; Mather, TN; Mizurini, DM; Monteiro, RQ; Reyes, M; Ribeiro, JMC | 1 |
| Han, M; Han, N; Liu, Z; Lv, G; Song, Z; Yin, J; Yu, B; Zhou, J | 1 |
| Cooley, BC; Kastetter, B; Matrai, AB | 1 |
| Adili, R; Chang, Z; Chen, YE; Eitzman, D; Fan, Y; Garcia-Barrio, MT; Holinstat, M; Hu, W; Liang, W; Lu, H; Sun, J; Wang, H; Wang, J; Zhang, J; Zhu, T | 1 |
| Ganson, NJ; Hershfield, MS; Layzer, JM; Moreno, A; Pitoc, GA; Sullenger, BA; Tarantal, AF | 1 |
| Anisimova, VA; Divaeva, LN; Kucheryavenko, AF; Kuz'menko, TA; Morkovnik, AS; Sirotenko, VS; Spasov, AA | 1 |
| Bode, C; Boeynaems, JM; Duerschmied, D; Guenther, F; Hein, L; Herr, N; Idzko, M; Mauler, M; Robaye, B; Roming, F; Von Zur Muhlen, C; Witsch, T | 1 |
| Assumpção, TC; Francischetti, IM; Kotsyfakis, M; Li, Y; Ma, D; Mizurini, DM; Monteiro, RQ; Qi, Y; Ribeiro, JM | 1 |
| Dai, X; Hou, Y; Lei, X; Li, BX; Liang, C; Marshall, AH; Ni, H; Reheman, A; Vanhoorelbeke, K; Wang, Y; Zhou, H | 1 |
| Gupta, N; Li, W; McIntyre, TM; Silverstein, RL; Willard, B | 1 |
| Borst, O; Chatterjee, M; Cosemans, JM; Elvers, M; Feijge, MA; Ferlinz, K; Gawaz, M; Gulbins, E; Heemskerk, JW; Lang, F; Leibrock, C; May, AE; Münzer, P; Schaller, M; Schmid, E; Schmidt, EM; Schmidt, S; Seizer, P; Towhid, ST; Walker, B | 1 |
| Heo, JH; Hong, SY; Kang, S; Kim, YD; Kwon, I; Nam, HS; Yang, SH | 1 |
| Baskaran, P; Berk, BC; Kim, Y; Modjeski, K; Morrell, CN; Smolock, EM; Soe, NN; Sowden, M; Wang, L; Xu, Y | 1 |
| Darbousset, R; Dignat-George, F; Dubois, C; Mezouar, S; Panicot-Dubois, L | 1 |
| Jackson, DE; Linden, MD; Mosawy, S; Woodman, OL | 1 |
| Brown, C; Crawford, B; Danisment, O; Hegadorn, CA; Lillicrap, D; Mewburn, J; Nieswandt, B; Pruss, CM; Rydz, N; Shida, Y; Sponagle, K; Stegner, D; Vidal, B | 1 |
| Coller, BS; Diacovo, TG; Filizola, M; Jiang, JK; Li, J; Nedelman, M; Negri, A; Shang, Y; Thomas, CJ; Vootukuri, S | 1 |
| Li, W; McIntyre, TM; Silverstein, RL; Srikanthan, S | 1 |
| Gigante, A; Hirano, M; Li, W; McIntyre, TM; Perez-Perez, MJ; Silverstein, RL; Yue, H | 1 |
| Cheng, Q; Gailani, D; Ivanov, IS | 1 |
| Bergeron, AL; Da, Q; Gushiken, FC; Khatlani, T; Langlois, KW; Molkentin, JD; Pradhan, S; Rumbaut, RE; Vijayan, KV | 1 |
| Funk, CD; Gong, Y; Li, X; Lin, M; Piao, L; Song, WL; Xiao, B; Yang, F; Yin, H; Yu, Y; Zhang, J; Zhang, Q; Zhu, L | 1 |
| Carvalho, LP; Chan, MY; Chen, W; Kang, TS; Kini, RM | 1 |
| Etscheid, M; Kanse, SM; Morowski, M; Nieswandt, B; Pragst, I; Sandset, PM; Subramaniam, S; Thielmann, I | 1 |
| Bhakta, V; Eltringham-Smith, LJ; Gataiance, S; Sheffield, WP | 2 |
| Borst, O; Chatterjee, M; Fischer, G; Gawaz, M; Heinzmann, D; Lang, F; Langer, H; Mack, AF; Malešević, M; May, AE; Münzer, P; Schmidt, EM; Schönberger, T; Seizer, P; Ungern-Sternberg, SN | 1 |
| Baek, JY; Chae, YH; Chang, TS; Hwang, GS; Jang, JY; Kim, M; Min, JH; Park, Y; Ryu, JS; Wang, SB | 1 |
| Fredenburgh, JC; Gross, PL; Jahnen-Dechent, W; Leslie, BA; Monia, BP; Ni, R; Qiao, S; Stafford, AR; Vaezzadeh, N; Vu, TT; Weitz, JI; Zhou, J | 1 |
| Andre, P; Bentley, R; Cai, TQ; Chen, Z; Desai, K; DiPietro, M; Hoos, L; Jochnowitz, N; Lai, K; Leander, K; Levorse, J; Metzger, JM; Seiffert, D; Sepp-Lorenzino, L; Shin, MK; Strapps, WR; Tadin-Strapps, M; Thankappan, A; Wu, W; Xu, Y; Zhang, Z; Zhou, Y | 1 |
| Ciciliano, JC; Dixon, JB; Fay, ME; Gachet, C; Hechler, B; Lam, WA; Li, R; Lyon, LA; Meeks, S; Myers, DR; Sakurai, Y | 1 |
| Chong, CM; Chu, IK; Cui, G; Guo, L; Hoi, MP; Lee, SM; Li, G; Quan, Q; Shan, L; Sun, Y; Wang, Y; Yu, P; Zhang, Z; Zhao, Y | 1 |
| Bonnard, T; Hagemeyer, CE | 1 |
| Bentley, R; Cai, TQ; Chen, Z; Hoos, L; Jochnowitz, N; Metzger, JM; Ogletree, ML; Seiffert, DA; Shin, MK; Strapps, W; Tadin-Strapps, M; Thankappan, A; Wu, W; Xu, Y; Zhou, Y | 1 |
| Goggs, R; Harper, MT; Offermanns, S; Poole, AW; Walsh, TG; Williams, CM | 1 |
| Feng, Q; Li, S; Peng, S; Wang, F; Wang, Y; Wu, J; Wu, W; Zhang, X; Zhao, M; Zhao, S | 1 |
| Alzoubi, K; Borst, O; Chatterjee, M; Chen, H; Elvira, B; Föller, M; Gawaz, M; Lang, F; Liu, G; Luo, D; Mak, TW; Münzer, P; Umbach, AT; Voelkl, J; Walker, B | 1 |
| Gupta, N; Li, W; McIntyre, TM | 1 |
| Jakubowski, JA; Mizuno, M; Ohno, K; Sugidachi, A; Tomizawa, A | 1 |
| Jackson, SP; Schoenwaelder, SM | 1 |
| Hu, H; Hu, M; Huang, Q; Liu, P; Liu, Y; Lu, L; Luo, D; Niu, Y; Wang, S; Yu, S; Yue, M; Zhou, Q | 1 |
| Brown, JM; Buffa, JA; DiDonato, JA; Fu, X; Gregory, JC; Gupta, N; Hazen, SL; Li, L; Lusis, AJ; McIntyre, TM; Mehrabian, M; Org, E; Sartor, RB; Silverstein, RL; Tang, WHW; Wang, Z; Wu, Y; Zhu, W | 1 |
| Hu, LF; Li, Q; Liu, CF; Qin, YR; Wang, F; Wang, XH; You, SJ; Zhang, Y | 1 |
| Cui, H; Hedin, U; Li, JP; Österholm, C; Tan, YX; Vlodavsky, I; Zhang, X | 1 |
| Chepurko, E; Covarrubias, R; Cowan, PJ; Dwyer, KM; Gumina, RJ; Huttinger, R; Huttinger, ZM; Novitskaya, T; Reynolds, A; Robson, SC; Stanfill, K; Wheeler, DG | 1 |
| Chauhan, AK; Dhanesha, N; Doddapattar, P; Khanna, I; Nayak, MK; Pollpeter, MJ; Prakash, P; Staber, JM | 1 |
| Huo, Z; Li, C; Wang, R; Wang, Z; Zhao, Z | 1 |
| Chien, CT; Chueh, TH; Hsia, CP; Tien, AJ | 1 |
| Cao, Y; Gu, J; Huang, W; Ji, C; Lee, KH; Li, K; Ma, L; Morris-Natschke, SL; Niu, H; Qin, C; Wei, Z; Wen, L; Xia, Q; Xin, G; Xing, Z; Yeh, JL; Zhang, R; Zheng, H | 1 |
| Ambily, A; Authi, KS; Bender, M; Braun, A; Dietrich, A; Gudermann, T; Hassock, SR; Nieswandt, B; Varga-Szabo, D | 1 |
| Chuah, MK; De Meyer, SF; Deckmyn, H; Lenting, PJ; Pareyn, I; Petrus, I; VandenDriessche, T; Vandeputte, N; Vanhoorelbeke, K | 1 |
| Bae, ON; Chung, JH; Chung, SM; Hong, S; Kim, K; Kim, YD; Lim, KM; Noh, JY; Shin, S; Yoon, JH | 1 |
| Li, W; Robertson, JO; Silverstein, RL; Smith, JD; Topol, EJ | 1 |
| Mackman, N; Miller, C; Rao, M; Swarthout, RF; Taubman, MB; Wang, L | 1 |
| Bhatt, S; Jain, MR; Patel, PR; Sharma, A; Soni, H | 1 |
| Denofrio, JC; Gentry, HR; Parise, LV; Temple, BR; Yuan, W | 1 |
| Chamberlain, J; Crosdale, DJ; Evans, DJ; Francis, SE; Jackman, LE; Jetha, K; Judge, HM; Norman, KE; Storey, RF | 1 |
| Banno, F; Chauhan, AK; Kokame, K; Miyata, S; Miyata, T; Wagner, DD; Yang, J | 1 |
| Eguchi, Y; Higashijima, N; Ishida, H; Ishizuka, N; Kawamura, Y; Takahari, Y; Tamura, N | 1 |
| Dieudé, M; Gillis, MA; Lajoie, G; Levine, JS; Merhi, Y; Rauch, J; Théorêt, JF; Thorin, E | 1 |
| Chin-Dusting, JP; Jackson, SP; Salem, HH; Sturgeon, S; Woollard, KJ | 1 |
| Chung, AD; Funk, CD; Mewburn, JD; Seta, F; Turner, PV; Yu, Y | 1 |
| Buerkle, MA; Hellwig, N; Klauss, V; Krötz, F; Mannell, H; Pircher, J; Pohl, U; Sohn, HY; Struthmann, L | 1 |
| Ashman, LK; Chand, R; Goschnick, MW; Jackson, DE; Orlowski, E; Wong, C; Wright, MD; Yip, J | 1 |
| Møller, F; Tranholm, M | 1 |
| Furie, B | 1 |
| Eguchi, Y; Goto, S; Ishida, H; Kawamura, Y; Takahari, Y; Tamura, N; Urano, T | 1 |
| Cabou, C; Chicanne, G; Gratacap, MP; Guillermet-Guibert, J; Jandrot-Perrus, M; Martin, V; Payrastre, B; Plantavid, M; Vanhaesebroeck, B | 1 |
| Golder, M; Hegadorn, C; Laverty, K; Lillicrap, D; Mewburn, J; Pruss, CM; Sponagle, K | 1 |
| Gross, PL; Kretz, CA; Vaezzadeh, N | 1 |
| Caicedo, J; Dong, A; Gairola, CG; Han, SG; Mueller, P; Saha, S; Smyth, SS | 1 |
| Fisslthaler, B; Fleming, I; Frömel, T; Isaak, J; Preissner, KT; Randriamboavonjy, V; Viollet, B | 1 |
| Mousa, SA | 1 |
| Elg, M; Johansson, K; Kjaer, M; Pehrsson, S | 1 |
| Chatterjee, M; Hu, H; Huang, Z; Ji, Q; Li, N; Zhang, W; Zhu, L | 1 |
| Akkerman, JW; Cate, HT; Hauer, AD; Hildebrand, RB; Hoekstra, M; Korporaal, SJ; Kuiper, J; Meurs, I; Praticò, D; Van Berkel, TJ; Van Eck, M | 1 |
| Cazenave, JP; Eckly, A; Freund, M; Gachet, C; Hechler, B; Lanza, F; Mangin, PH; Zerr, M | 1 |
| Dalkara, T; Dunn, AK; Erdener, SE; Gurer, G; Gursoy-Ozdemir, Y; Karatas, H; Soylemezoglu, F | 1 |
| Cardenas, JC; Church, FC; Machlus, KR; Wolberg, AS | 1 |
| Brill, A | 1 |
| Cooley, BC | 1 |
| Bae, IH; Chung, JH; Jeong, YS; Kim, CW; Lim, KM; Park, JW; Park, YH; Yun, JW | 1 |
| Bender, M; Hagedorn, I; Nieswandt, B | 1 |
| Benguigui, LE; Deeb, RS; Hajjar, DP; Hajjar, KA; Lamon, BD; Shen, H; Upmacis, RK | 1 |
| Hagemeyer, CE; Heidt, T; Jackson, KE; Jia, F; Leitner, E; Nair, AK; Pearce, H; Peter, K; Prabhu, S; Ta, HT; von Elverfeldt, D; von Zur Muhlen, C; Wang, X | 1 |
| Jin, SY; Sorvillo, N; Voorberg, J; Xiao, J; Xue, J; Zheng, XL | 1 |
| Lin, FC; Machlus, KR; Wolberg, AS | 1 |
| Alonso-Martín, S; Ayuso, MS; Fernández, D; González-Manchón, C; Larrucea, S; Parrilla, R; Pericacho, M; Sánchez, I | 1 |
| Kim, JK; Kwon, OC; Lee, S; Min, SK; Park, KH | 1 |
| Braun, A; Dietrich, A; Gupta, S; Mannhalter, C; May, F; Nieswandt, B; Pleines, I; Ramanathan, G; Thielmann, I; Varga-Szabo, D | 1 |
| Christophe, OD; de Groot, PG; Denis, CV; Lenting, PJ; Odouard, S; Oortwijn, BD; Pegon, JN; Saint-Lu, N | 1 |
| Bryant, A; Golder, M; Haberichter, S; Hegadorn, C; Lillicrap, D; Pruss, CM | 1 |
| Barbera, F; Bird, JE; Revelli, JP; Schumacher, WA; Seiffert, D; Smith, PL; Wang, X | 1 |
| Boulaftali, Y; Bouton, MC; Ho-Tin-Noé, B; Jandrot-Perrus, M; Lamrani, L; Loyau, S; Rouzaud, MC | 1 |
| Buczko, W; Kalaska, B; Kaminski, K; Kramkowski, K; Mogielnicki, A; Nowakowska, M; Sokolowska, E; Szczubialka, K | 1 |
| Assumpção, TC; Collin, N; Dutra-Oliveira, A; Francischetti, IM; Gilmore, DC; Kotsyfakis, M; Mizurini, DM; Monteiro, RQ; Ribeiro, JM; Sá-Nunes, A; Teixeira, C; Valenzuela, JG | 1 |
| Ding, Z; Du, H; Liu, G; Pan, C; Wei, X; Ye, J; Zhang, S; Zhang, Y | 1 |
| Ding, Z; Hu, L; Kunapuli, SP; Li, Y; Ye, J; Zhang, S; Zhang, SH; Zhang, Y | 1 |
| Casari, C; Christophe, OD; Denis, CV; Hu, JR; Legendre, P; Lenting, PJ; Marx, I; Navarrete, AM | 1 |
| Bachmann, S; Dütting, S; Hagedorn, I; Italiano, JE; Kunert, S; Meyer, I; Nieswandt, B; Schulze, H; Schwiebert, S | 1 |
| Bester, J; Lipinski, B; Pretorius, E; Vermeulen, N | 1 |
| Golder, M; Lillicrap, D; Mewburn, J | 1 |
| Rossaint, J; Vestweber, D; Zarbock, A | 1 |
| Barr, JD; Chauhan, AK; Hansen, JK; Motto, DG; Schaeffer, GV | 1 |
| Castellino, FJ; Haalboom, E; Liang, Z; Martin, JA; Rosen, ED; Sandoval-Cooper, MJ; Volkir, SP | 1 |
| Coughlin, SR; Hamilton, JR; Lease, KE; Weiss, EJ | 1 |
| Peng, S; Tang, Z; Wang, Y; Xiao, Y; Zhao, M | 1 |
| Cooley, BC; Hendrickson, SB; Hernandez, I; Isermann, BH; Kerlin, B; Lord, S; Mosesson, MW; Sood, R; Weiler, H; Zogg, M | 1 |
| Bordel, R; Lindenblatt, N; Menger, MD; Schareck, W; Vollmar, B | 1 |
| Ho, NH; Houng, AK; Jaffer, FA; Reed, GL; Tung, CH; Weissleder, R; Wykrzykowska, JJ | 1 |
| Chi, L; Edmunds, JJ; Gibson, G; Hicks, G; Janiczek, N; Leadley, R; Mertz, TE; Peng, YW; Rapundalo, S | 1 |
| Golubykh, VL; Maksimenko, AV; Tischenko, EG | 1 |
| Wang, X; Xu, L | 1 |
| Hayashi, K; Iwatsuki, Y; Kawasaki, T; Miyata, K; Moritani, Y; Nii, T | 1 |
| Kasuya, Y; Kimura, S; Matsuo, Y; Sakurai, K; Sudo, T; Takuwa, Y | 1 |
| Cheng, Q; Feuerstein, GZ; Gailani, D; Hsu, MY; Ogletree, ML; Schumacher, WA; Seiffert, DA; Smith, PL; Wang, X; Xu, L | 1 |
| Budihna, MV; Cerne, M; Drevensek, G; Peternel, L; Stalc, A; Stegnar, M | 1 |
| Hayashi, K; Kawasaki, T; Moritani, Y; Nagai, K; Saito, T; Shigenaga, T; Takamatsu, H; Takasaki, J; Taniguchi, M; Uemura, T | 1 |
| Du, X; Li, Z; Marjanovic, JA; Stojanovic, A | 1 |
| Barrett, NE; Cooley, B; Falati, S; Furie, B; Furie, BC; Gibbins, JM; Gross, PL; Merrill-Skoloff, G; Newman, DK; Newman, PJ; Patil, S; Pixton, KL; Stapleton, M; Weiler, H | 1 |
| Crain, K; Konstantinides, S; Koschnick, S; Loskutoff, DJ; Schäfer, K | 1 |
| Dubois, C; Furie, B; Furie, BC; Merrill-Skoloff, G; Panicot-Dubois, L | 1 |
| Dellas, C; Hasenfuss, G; Konstantinides, SV; Nitsche, M; Puls, M; Schäfer, K; Schroeter, MR; Weiss, E | 1 |
| Astrof, S; Cambien, B; Chauhan, AK; Dole, VS; Hynes, RO; Matuskova, J; Piffath, CL; Wagner, DD | 1 |
| Douglas, SA; Erhardt, JA; Johns, DG; Toomey, JR | 1 |
| Ahrens, I; Bassler, N; Bode, C; Chen, YC; Fitzgerald, D; Hagemeyer, CE; Kenny, D; Meade, G; Moran, N; Peter, K; Schwarz, M; Stoll, P; Ylanne, J | 1 |
| Chen, CY; Cooley, BC; Schmeling, G | 1 |
| Hsu, MY; Monticello, TM; Schumacher, WA; Steinbacher, TE; Wang, X | 1 |
| Hayashi, H; Ito, H; Nagamura, Y; Sudo, T; Toga, K; Yamada, Y | 1 |
| Cong, Y; Deng, X; Li, J; Li, S; Li, X; Li, Y | 1 |
| Boehncke, WH; Krahn, T; Ludwig, RJ; Nieswandt, B; Oostingh, GJ; Pozgajova, M; Schön, MP | 1 |
| Chiang, TM; Du, H; Gaber, MW; Zawaski, JA | 1 |
| Eitzman, DT; Westrick, RJ; Winn, ME | 1 |
| Ablooglu, AJ; Fogelstrand, P; Ginsberg, MH; Partridge, AW; Petrich, BG; Shattil, SJ; Yousefi, N | 1 |
| Cleuren, AC; Hoylaerts, MF; Lijnen, HR; Nagai, N; Rosendaal, FR; Van Hoef, B; Van Vlijmen, BJ | 1 |
| Cosemans, JM; Eckes, B; Heemskerk, JW; Kuijpers, MJ; Munnix, IC; Nieswandt, B; Pozgajova, M | 1 |
| Critchley, D; Fässler, R; Monkley, S; Moser, M; Nieswandt, B; Pleines, I; Varga-Szabo, D | 1 |
| Abrink, M; August, S; Kowalska, MA; Lilliendahl, JK; Pejler, G; Rauova, L; Schick, BP; White, JG; Woulfe, DS | 1 |
| August, S; Li, D; Woulfe, DS | 1 |
| Cleuren, AC; Hoylaerts, MF; Lijnen, HR; Nagai, N; Van Vlijmen, BJ | 1 |
| Hirayama, N; Ishida, H; Izuhara, Y; Kurokawa, K; Miyata, T; Nangaku, M; Takahashi, S; Takizawa, S; van Ypersele de Strihou, C | 1 |
| Berges, A; Humboldt, T; Konstantinides, S; Lebrun, S; Leifheit, M; Meurrens, K; Sawalich, M; Schaefer, K; Schleef, R; Schroeter, MR; Wallerath, T; Xu, H | 1 |
| Wang, X | 1 |
| Allegretto, N; Barbera, F; Bird, JE; Giancarli, MR; Ogletree, ML; Schumacher, WA; Seiffert, D; Wong, P | 1 |
| Ding, WH | 1 |
| Chen, IW; Chen, Z; Cook, JJ; Cutrona, KJ; Dorsey, BD; Dyer, DL; Gardell, SJ; Krueger, JA; Lewis, SD; Lin, JH; Lucas, BJ; Lyle, EA; Lynch, JJ; McDonough, CM; Naylor-Olsen, AM; Sanderson, PE; Shafer, JA; Stranieri, MT; Vacca, JP; Vastag, K | 1 |
| Khan, S; Li, D; Mehta, JL; Nichols, WW; Saldeen, T; Weng, S; Yang, B; Zander, DS | 1 |
| Fukazawa, T; Goto, Y; Hayashi, H; Inoue, Y; Komatsu, Y | 1 |
| Kambayashi, J; Lockyer, S | 1 |
| Carmeliet, P; Fay, WP; Zhu, Y | 1 |
| Kurimoto, T; Sato, R; Tanaka, T | 1 |
| Konstantinides, S; Loskutoff, DJ; Schäfer, K; Thinnes, T | 1 |
| Farrehi, PM; Fay, WP; Zhu, Y | 1 |
| Coller, BS; Reis, ED; Smyth, SS; Väänänen, H; Zhang, W | 1 |
| Conway, EM; Cooley, BC; Hendrickson, SB; Isermann, BH; Kerlin, B; Lindner, V; Meh, DA; Mosesson, MW; Post, MJ; Shworak, NW; Ulfman, LH; von Andrian, UH; Weiler, H; Weitz, JI | 1 |
| Calvio, AM; Colli, S; Mussoni, L; Sironi, L; Tedeschi, L; Tremoli, E | 1 |
| André, P; Denis, CV; He, M; Hynes, RO; Papalia, JM; Phillips, DR; Prasad, KS; Wagner, DD | 1 |
4 review(s) available for ferric chloride and Blood Clot
| Article | Year |
|---|---|
Involvement of neutrophils in thrombus formation in living mice.
Topics: Animals; Arteries; Blood Proteins; Chlorides; Computer Systems; Cytoplasmic Granules; Disease Models, Animal; Endothelium, Vascular; Extracellular Matrix; Ferric Compounds; Lasers; Mice; Microcirculation; Neutrophil Infiltration; Neutrophils; Platelet Activation; Thromboplastin; Thrombosis | 2014 |
Pathogenesis of thrombosis.
Topics: Animals; Blood Coagulation Factors; Cell-Derived Microparticles; Chlorides; Collagen; Disease Models, Animal; Ferric Compounds; Fibrin; Integrin beta3; Lasers; Mesentery; Mice; Mice, Knockout; Microscopy, Fluorescence; Muscle, Skeletal; Platelet Aggregation; Protein Disulfide-Isomerases; Thromboplastin; Thrombosis | 2009 |
Tissue factor and thrombosis models.
Topics: Animals; Blood Coagulation; Blood Vessels; Chlorides; Disease Models, Animal; Evidence-Based Medicine; Ferric Compounds; Genotype; Mice; Mice, Transgenic; Phenotype; Reproducibility of Results; Thromboplastin; Thrombosis | 2010 |
Murine models of vascular thrombosis (Eitzman series).
Topics: Animals; Atherosclerosis; Blood Coagulation; Blood Vessels; Chlorides; Collagen; Disease Models, Animal; Epinephrine; Ferric Compounds; Genotype; Lasers; Mice; Mice, Transgenic; Microscopy, Fluorescence; Microscopy, Video; Phenotype; Reproducibility of Results; Rose Bengal; Species Specificity; Thrombosis | 2007 |
181 other study(ies) available for ferric chloride and Blood Clot
| Article | Year |
|---|---|
Repeated Social Defeat Exaggerates Fibrin-Rich Clot Formation by Enhancing Neutrophil Extracellular Trap Formation via Platelet-Neutrophil Interactions.
Topics: Animals; Antibodies; Blood Coagulation; Blood Platelets; CD11b Antigen; Cell Communication; Chlorides; Deoxyribonuclease I; Extracellular Traps; Ferric Compounds; Fibrin; Male; Mice, Inbred C57BL; Neutrophils; P-Selectin; Platelet Aggregation; Social Defeat; Thrombosis | 2021 |
Evaluation of Sida cordifolia L. for its potential against thrombosis in experimental models.
Topics: Animals; Anticoagulants; Carrageenan; Chlorides; Collagen; Epinephrine; Female; Ferric Compounds; Lung; Male; Mice; Phytochemicals; Plant Extracts; Rats; Rats, Wistar; Sida Plant; Thrombosis | 2022 |
Plasminogen activator-coated nanobubbles targeting cellbound β2-glycoprotein I as a novel thrombus-specific thrombolytic strategy.
Topics: Animals; Antiphospholipid Syndrome; beta 2-Glycoprotein I; Endothelial Cells; Fibrinolytic Agents; Mice; Rats; Thromboembolism; Thrombosis; Tissue Plasminogen Activator | 2023 |
Ferric Chloride-Induced Arterial Thrombosis and Sample Collection for 3D Electron Microscopy Analysis.
Topics: Blood Platelets; Ferric Compounds; Fibrinolytic Agents; Hemorrhage; Humans; Microscopy, Electron; Thrombosis | 2023 |
CTSS Modulates Stress-Related Carotid Artery Thrombosis in a Mouse FeCl
Topics: Animals; Cardiovascular Diseases; Carotid Artery Thrombosis; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Mice; Plasminogen Activator Inhibitor 1; Thrombosis; von Willebrand Factor | 2023 |
The mechanism of oleic acid inhibiting platelet activation stimulated by collagen.
Topics: Animals; Blood Platelets; Collagen; Fibrinogen; Humans; Mice; Oleic Acid; Phosphorylation; Platelet Activation; Thrombosis | 2023 |
Effective Prevention of Arterial Thrombosis with Albumin-Thrombin Inhibitor Conjugates.
Topics: Amino Acid Chloromethyl Ketones; Animals; Anticoagulants; Humans; Ischemia; Mice; Thrombin; Thrombosis; Venous Thromboembolism | 2023 |
A synthetic heparin mimetic that allosterically inhibits factor XIa and reduces thrombosis in vivo without enhanced risk of bleeding.
Topics: Allosteric Regulation; Animals; Anticoagulants; Blood Coagulation; Chlorides; Disease Models, Animal; Factor XIa; Female; Ferric Compounds; Hemorrhage; Heparin; Humans; Inositol; Molecular Mimicry; Rats, Wistar; Risk Assessment; Sulfates; Thrombosis | 2019 |
Antithrombotic Effect of Artemisia princeps Pampanini Extracts in Vitro and in FeCl
Topics: Adult; Animals; Artemisia; Cell Adhesion; Cell Adhesion Molecules; Chlorides; Female; Ferric Compounds; Fibrinolytic Agents; Humans; Male; Monocytes; Plant Extracts; Rats; Rats, Sprague-Dawley; Thrombosis; Tumor Necrosis Factor-alpha; Young Adult | 2019 |
Cyclic RGD functionalized liposomes targeted to activated platelets for thrombosis dual-mode magnetic resonance imaging.
Topics: Animals; Blood Platelets; Chlorides; Ferric Compounds; Gadolinium DTPA; Liposomes; Magnetic Resonance Imaging; Male; Materials Testing; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Thrombosis | 2020 |
Cyclic peptide FXII inhibitor provides safe anticoagulation in a thrombosis model and in artificial lungs.
Topics: Animals; Anticoagulants; Blood Coagulation; Chlorides; Cloning, Molecular; Disease Models, Animal; Drug Discovery; Extracorporeal Membrane Oxygenation; Factor XII; Factor XIIa; Female; Ferric Compounds; Humans; Lung; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptides, Cyclic; Rabbits; Recombinant Proteins; Swine; Thrombosis | 2020 |
Aqueous extract of Whitmania pigra Whitman ameliorates ferric chloride-induced venous thrombosis in rats via antioxidation.
Topics: Animals; Antioxidants; Chlorides; Ferric Compounds; Leeches; NF-E2-Related Factor 2; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Thrombosis; Venous Thrombosis | 2021 |
Thrombospondin-1 promotes hemostasis through modulation of cAMP signaling in blood platelets.
Topics: Animals; Bleeding Time; Blood Platelets; CD36 Antigens; Cells, Cultured; Chlorides; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Cytoplasmic Granules; Epoprostenol; Ferric Compounds; Hemorrhagic Disorders; Hemostasis; Humans; Iloprost; Mice; Mice, Inbred C57BL; Platelet Transfusion; Second Messenger Systems; Thrombosis; Thrombospondin 1 | 2021 |
Adenosine Receptor Agonist HE-NECA Enhances Antithrombotic Activities of Cangrelor and Prasugrel in vivo by Decreasing of Fibrinogen Density in Thrombus.
Topics: Adenosine Monophosphate; Adenosine-5'-(N-ethylcarboxamide); Adult; Animals; Antithrombins; Blood Pressure; Blood-Brain Barrier; Chlorides; Diastole; Female; Ferric Compounds; Fibrinogen; Humans; Laser-Doppler Flowmetry; Male; Mice, Inbred C57BL; Permeability; Platelet Activation; Platelet Aggregation; Prasugrel Hydrochloride; Purinergic P1 Receptor Agonists; Purinergic P2Y Receptor Antagonists; Systole; Thrombosis | 2021 |
Mice Lacking the Inhibitory Collagen Receptor LAIR-1 Exhibit a Mild Thrombocytosis and Hyperactive Platelets.
Topics: Animals; Blood Platelets; Carrier Proteins; Cells, Cultured; Chlorides; Disease Models, Animal; Enzyme Activation; Ferric Compounds; Genetic Predisposition to Disease; Megakaryocytes; Mice, Knockout; Peptides; Phenotype; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoproteins; Receptors, IgG; Receptors, Immunologic; Signal Transduction; src-Family Kinases; Thrombocytosis; Thrombosis | 2017 |
Fibrin-Targeted and H
Topics: Animals; Boronic Acids; Carotid Artery Thrombosis; CD40 Ligand; Cell Survival; Chlorides; Drug Carriers; Drug Liberation; Endothelial Cells; Ferric Compounds; Fibrin; Fibrinolytic Agents; Fluorescent Dyes; Humans; Hydrogen Peroxide; Lipopeptides; Mice; Nanoparticles; Optical Imaging; Polymers; RAW 264.7 Cells; Theranostic Nanomedicine; Thrombosis; Tirofiban; Tumor Necrosis Factor-alpha | 2017 |
Potent Thrombolytic Effect of
Topics: Acetylcysteine; Animals; Blood Platelets; Chlorides; Disease Models, Animal; Ferric Compounds; Fibrinolytic Agents; Infarction, Middle Cerebral Artery; Male; Mice; Platelet Aggregation; Ristocetin; Thromboembolism; Thrombosis; Tissue Plasminogen Activator; von Willebrand Factor | 2017 |
Endogenous tissue factor pathway inhibitor in vascular smooth muscle cells inhibits arterial thrombosis.
Topics: Animals; Chlorides; Endothelial Cells; Ferric Compounds; Hemostasis; Immunohistochemistry; Lipoproteins; Mice; Mice, Knockout; Myocytes, Smooth Muscle; Thrombosis | 2017 |
Trowaglerix Venom Polypeptides As a Novel Antithrombotic Agent by Targeting Immunoglobulin-Like Domains of Glycoprotein VI in Platelet.
Topics: Animals; Binding Sites; Blood Platelets; Carotid Artery Injuries; Chlorides; Computer-Aided Design; Crotalid Venoms; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Ferric Compounds; Fibrinolytic Agents; Fluorescein; Hemorrhage; Humans; Lectins, C-Type; Male; Mice, Inbred ICR; Molecular Docking Simulation; Peptide Fragments; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Protein Binding; Protein Interaction Domains and Motifs; Signal Transduction; Thrombosis | 2017 |
Platelets Express Activated P2Y
Topics: Adenosine Monophosphate; Animals; Blood Platelets; Cell Adhesion Molecules; Cell Line; Chlorides; Cyclic AMP; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Drug Inverse Agonism; Ferric Compounds; Fibrinolytic Agents; Humans; Male; Microfilament Proteins; NF-kappa B; Phosphoproteins; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, Purinergic P2Y12; Thrombosis | 2017 |
Interferon lambda1/IL-29 and inorganic polyphosphate are novel regulators of neutrophil-driven thromboinflammation.
Topics: Animals; Autophagy; Blood Coagulation; Blood Platelets; Case-Control Studies; Chlorides; Disease Models, Animal; Extracellular Traps; Ferric Compounds; Humans; Inflammation; Interferons; Interleukins; Male; Mice, Inbred C57BL; Neutrophils; Platelet Activation; Polyphosphates; Signal Transduction; ST Elevation Myocardial Infarction; Thrombin; Thrombosis; TOR Serine-Threonine Kinases | 2017 |
Photoacoustic Imaging: A Novel Tool for Detecting Carotid Artery Thrombosis in Mice.
Topics: Animals; Biopsy; Carotid Artery Diseases; Carotid Artery, Common; Chlorides; Disease Models, Animal; Ferric Compounds; Male; Mice, Inbred ICR; Photoacoustic Techniques; Predictive Value of Tests; Thrombosis; Time Factors; Ultrasonography, Doppler, Color | 2017 |
ADPase CD39 Fused to Glycoprotein VI-Fc Boosts Local Antithrombotic Effects at Vascular Lesions.
Topics: Animals; Antigens, CD; Apyrase; Carotid Artery Diseases; Carotid Artery Injuries; Chlorides; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Ferric Compounds; Fibrinolytic Agents; Glycoproteins; Hemorrhage; Humans; Immunoglobulin Fc Fragments; Male; Mice, Inbred C57BL; Plaque, Atherosclerotic; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Recombinant Fusion Proteins; Thrombosis | 2017 |
ARHGEF10 knockout inhibits platelet aggregation and protects mice from thrombus formation.
Topics: Animals; Arterial Occlusive Diseases; Blood Platelets; Carotid Artery Diseases; Cell Shape; Chlorides; Disease Models, Animal; Ferric Compounds; Gene Knockout Techniques; Genotype; Hemostasis; Male; Mice, 129 Strain; Mice, Knockout; Myosin Light Chains; Phenotype; Phosphorylation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Rho Guanine Nucleotide Exchange Factors; Selenoprotein P; Thrombosis; Time Factors | 2017 |
Class III PI3K Positively Regulates Platelet Activation and Thrombosis via PI(3)P-Directed Function of NADPH Oxidase.
Topics: Adult; Animals; Autophagy; Blood Coagulation; Blood Platelets; Chlorides; Class III Phosphatidylinositol 3-Kinases; Collagen; Disease Models, Animal; Female; Ferric Compounds; Genotype; Humans; Male; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Phenotype; Phosphatidylinositol Phosphates; Platelet Activation; Platelet Aggregation; Reactive Oxygen Species; Signal Transduction; Thrombin; Thrombosis; Time Factors; TOR Serine-Threonine Kinases; Young Adult | 2017 |
Histological comparison of arterial thrombi in mice and men and the influence of Cl-amidine on thrombus formation.
Topics: Aged; Animals; Chlorides; Coronary Vessels; Disease Models, Animal; Female; Ferric Compounds; Humans; Male; Mice; Middle Aged; Myocardial Infarction; Ornithine; Prospective Studies; Thrombosis | 2018 |
Anti-thrombotic efficacy of S007-867: Pre-clinical evaluation in experimental models of thrombosis in vivo and in vitro.
Topics: Animals; Aspirin; Blood Coagulation; Chlorides; Clopidogrel; Dose-Response Relationship, Drug; Ferric Compounds; Fibrinolytic Agents; Male; Mice; Piperidines; Platelet Adhesiveness; Platelet Aggregation; Pyrrolidines; Rats; Rats, Sprague-Dawley; Thrombosis | 2018 |
Fusion to Human Serum Albumin Extends the Circulatory Half-Life and Duration of Antithrombotic Action of the Kunitz Protease Inhibitor Domain of Protease Nexin 2.
Topics: Amyloid beta-Protein Precursor; Animals; Area Under Curve; Blood Coagulation Factors; Chlorides; Chromatography, High Pressure Liquid; Disease Models, Animal; Ferric Compounds; Half-Life; Histidine; Humans; Iodine Radioisotopes; Mice; Oligopeptides; Protein Domains; Receptors, LDL; Recombinant Fusion Proteins; ROC Curve; Serum Albumin, Human; Spectrometry, Mass, Electrospray Ionization; Thrombosis | 2018 |
Ixonnexin from Tick Saliva Promotes Fibrinolysis by Interacting with Plasminogen and Tissue-Type Plasminogen Activator, and Prevents Arterial Thrombosis.
Topics: Animals; Arterial Occlusive Diseases; Chlorides; Ferric Compounds; Fibrinolysis; Mice; Noxae; Plasminogen; Saliva; Salivary Proteins and Peptides; Thrombosis; Ticks; Tissue Plasminogen Activator | 2018 |
Evaluation of the antithrombotic activity of Zhi-Xiong Capsules, a Traditional Chinese Medicinal formula, via the pathway of anti-coagulation, anti-platelet activation and anti-fibrinolysis.
Topics: Acute Disease; Animals; Anticoagulants; Antithrombins; Aspirin; Blood Coagulation; Capsules; Carotid Arteries; Chlorides; Disease Models, Animal; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Ferric Compounds; Fibrinolysis; Heparin; Lung; Mice; Platelet Activation; Platelet Aggregation; Prostaglandins F; Pulmonary Embolism; Rabbits; Rats, Sprague-Dawley; Thrombolytic Therapy; Thrombosis; Thromboxane B2 | 2018 |
Optimizing outcome measurement with murine ferric chloride-induced thrombosis.
Topics: Animals; Carotid Arteries; Chlorides; Factor IX; Ferric Compounds; Hemophilia B; Mice; Mice, Knockout; Thrombosis; Treatment Outcome | 2018 |
KLF11 (Krüppel-Like Factor 11) Inhibits Arterial Thrombosis via Suppression of Tissue Factor in the Vascular Wall.
Topics: Animals; Antithrombin III; Apoptosis Regulatory Proteins; Bone Marrow Transplantation; Cells, Cultured; Chlorides; Chromatin Immunoprecipitation; Down-Regulation; Female; Ferric Compounds; Gene Expression Regulation; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Peptide Hydrolases; Platelet Aggregation; Recombinant Proteins; Repressor Proteins; RNA Interference; Thromboplastin; Thrombosis; Transcription, Genetic | 2019 |
Anti-PEG Antibodies Inhibit the Anticoagulant Activity of PEGylated Aptamers.
Topics: Animals; Antibodies; Anticoagulants; Antigen-Antibody Reactions; Aptamers, Nucleotide; Chlorides; Disease Models, Animal; Factor IXa; Female; Ferric Compounds; Humans; Macaca mulatta; Mice; Mice, Inbred C57BL; Partial Thromboplastin Time; Polyethylene Glycols; Thrombosis | 2019 |
Antithrombotic Activity of a Novel Diazepino[1,2-α] Benzimidazole Derivative on Arterial Thrombosis Model in Rats without Concomitant Pathology and in Rats with Experimental Myocardial Infarction.
Topics: Animals; Animals, Outbred Strains; Aspirin; Azepines; Benzimidazoles; Blood Coagulation Tests; Chlorides; Clopidogrel; Disease Models, Animal; Ferric Compounds; Fibrinolytic Agents; Male; Myocardial Infarction; Platelet Aggregation; Rats; Thrombosis | 2019 |
Contrast ultrasound for the quantification of deep vein thrombosis in living mice: effects of enoxaparin and P2Y12 receptor inhibition.
Topics: Adenosine; Animals; Anticoagulants; Chlorides; Contrast Media; Enoxaparin; Ferric Compounds; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microbubbles; Microscopy; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Signal Transduction; Sulfur Hexafluoride; Thrombosis; Ticagrelor; Ultrasonography; Vena Cava, Inferior; Venous Thrombosis | 2013 |
Desmolaris, a novel factor XIa anticoagulant from the salivary gland of the vampire bat (Desmodus rotundus) inhibits inflammation and thrombosis in vivo.
Topics: Animals; Anticoagulants; Bradykinin; Chiroptera; Chlorides; Disease Models, Animal; Factor Xa; Factor Xa Inhibitors; Ferric Compounds; HEK293 Cells; Humans; Inflammation; Kallikreins; Mice; Noxae; Protein Structure, Tertiary; Salivary Proteins and Peptides; Thrombosis | 2013 |
Anfibatide, a novel GPIb complex antagonist, inhibits platelet adhesion and thrombus formation in vitro and in vivo in murine models of thrombosis.
Topics: Animals; Binding Sites; Blood Platelets; Chlorides; Crotalid Venoms; Disease Models, Animal; Female; Ferric Compounds; Fibrinolytic Agents; Hemorrhage; Lectins, C-Type; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIb-IX Complex; Protein Binding; Thrombosis; Time Factors; Vascular System Injuries; von Willebrand Factor | 2014 |
Proteasome proteolysis supports stimulated platelet function and thrombosis.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Cell-Derived Microparticles; Chlorides; Cytoskeletal Proteins; Disease Models, Animal; Ferric Compounds; Fibrinolytic Agents; Filamins; Humans; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation; Platelet Glycoprotein GPIb-IX Complex; Platelet Transfusion; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Proteolysis; Talin; Thrombin; Thrombosis; Time Factors; Ubiquitination | 2014 |
Acid sphingomyelinase regulates platelet cell membrane scrambling, secretion, and thrombus formation.
Topics: Adenosine Triphosphate; Animals; Blood Platelets; Calcium; Cell Degranulation; Cell Membrane; Ceramides; Chlorides; Disease Models, Animal; Enzyme Inhibitors; Female; Ferric Compounds; Fibrinolytic Agents; Male; Mice; Mice, Knockout; P-Selectin; Phosphatidylserines; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Sphingomyelin Phosphodiesterase; Thrombin; Thrombosis; Time Factors | 2014 |
Thrombolytic effects of the snake venom disintegrin saxatilin determined by novel assessment methods: a FeCl3-induced thrombosis model in mice.
Topics: Animals; Blood Platelets; Carotid Arteries; Cells, Cultured; Chlorides; Disintegrins; Dose-Response Relationship, Drug; Drug Administration Schedule; Ferric Compounds; Fibrinolytic Agents; Hemorheology; Hemorrhage; Integrins; Male; Mice; Mice, Inbred ICR; Platelet Aggregation; Snake Venoms; Thrombolytic Therapy; Thrombosis | 2013 |
Cyclophilin A is an important mediator of platelet function by regulating integrin αIIbβ3 bidirectional signalling.
Topics: Animals; Blood Platelets; Cell Adhesion; Cells, Cultured; Chlorides; Cyclophilin A; Cytoskeleton; Ferric Compounds; Fibrinogen; Hemorrhage; Mesenteric Arteries; Mice, Inbred C57BL; Mice, Knockout; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Reactive Oxygen Species; Signal Transduction; Thrombin; Thrombosis | 2014 |
The flavonols quercetin and 3',4'-dihydroxyflavonol reduce platelet function and delay thrombus formation in a model of type 1 diabetes.
Topics: Animals; Antioxidants; Blood Platelets; Carotid Arteries; Carotid Artery Injuries; Chlorides; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Exocytosis; Ferric Compounds; Flavonols; Laser-Doppler Flowmetry; Mice; Mice, Inbred C57BL; Platelet Activation; Platelet Aggregation; Quercetin; Thrombosis | 2014 |
Analysis of the role of von Willebrand factor, platelet glycoprotein VI-, and α2β1-mediated collagen binding in thrombus formation.
Topics: Amino Acid Substitution; Animals; Chlorides; Collagen; Disease Models, Animal; Ferric Compounds; HEK293 Cells; Humans; Integrin alpha2beta1; Mice; Mice, Knockout; Mutation, Missense; Noxae; Platelet Membrane Glycoproteins; Protein Structure, Tertiary; Thrombosis; von Willebrand Factor | 2014 |
RUC-4: a novel αIIbβ3 antagonist for prehospital therapy of myocardial infarction.
Topics: Animals; Binding Sites; Blood Platelets; Carotid Stenosis; Chlorides; Disease Models, Animal; Emergency Medical Services; Ferric Compounds; Fibrinolytic Agents; Humans; Macaca fascicularis; Male; Mice; Mice, Transgenic; Molecular Dynamics Simulation; Myocardial Infarction; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Protein Conformation; Pyrimidinones; Solubility; Thiadiazoles; Thrombosis; von Willebrand Factor | 2014 |
Exosome poly-ubiquitin inhibits platelet activation, downregulates CD36 and inhibits pro-atherothombotic cellular functions.
Topics: Animals; Blood Platelets; Carotid Artery Diseases; CD36 Antigens; Cell-Derived Microparticles; Chlorides; Cholesterol; Collagen; Disease Models, Animal; Exosomes; Ferric Compounds; Foam Cells; Humans; Lipoproteins, LDL; Mice, Inbred C57BL; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation; Platelet Transfusion; Polyubiquitin; Proteasome Endopeptidase Complex; Proteolysis; Signal Transduction; Thrombocytopenia; Thrombosis; Time Factors; Ubiquitination | 2014 |
Thymidine phosphorylase participates in platelet signaling and promotes thrombosis.
Topics: Amino Acid Sequence; Animals; Blood Platelets; Bone Marrow Transplantation; Chlorides; Enzyme Inhibitors; Ferric Compounds; Haploinsufficiency; Humans; Male; Mice, Inbred C57BL; Mice, Knockout; Molecular Sequence Data; Phenotype; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Transfusion; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-fyn; Proto-Oncogene Proteins c-yes; Selenoprotein P; Signal Transduction; src-Family Kinases; Thrombosis; Thymidine Phosphorylase; Time Factors | 2014 |
Murine models in the evaluation of heparan sulfate-based anticoagulants.
Topics: Animals; Anticoagulants; Chlorides; Disease Models, Animal; Ferric Compounds; Hemorrhage; Heparitin Sulfate; Mice, Inbred C57BL; Tail; Thrombosis; Vena Cava, Inferior | 2015 |
The β isoform of the catalytic subunit of protein phosphatase 2B restrains platelet function by suppressing outside-in αII b β3 integrin signaling.
Topics: Animals; Blood Platelets; Calcineurin; Carotid Arteries; Catalytic Domain; Cell Adhesion; Chlorides; Female; Ferric Compounds; Fibrinogen; Flow Cytometry; HEK293 Cells; Humans; Male; Mice; Mice, Transgenic; Phenotype; Phosphorylation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Isoforms; Signal Transduction; Thrombosis | 2014 |
Aspirin enhances protective effect of fish oil against thrombosis and injury-induced vascular remodelling.
Topics: Animals; Aspirin; Chlorides; Dietary Supplements; Dose-Response Relationship, Drug; Drug Synergism; Femoral Artery; Ferric Compounds; Fish Oils; Male; Mice; Mice, Inbred Strains; Photochemical Processes; Platelet Aggregation; Structure-Activity Relationship; Thrombosis; Vascular System Injuries | 2015 |
Fasxiator, a novel factor XIa inhibitor from snake venom, and its site-specific mutagenesis to improve potency and selectivity.
Topics: Amino Acid Sequence; Animals; Binding, Competitive; Blood Coagulation; Bungarotoxins; Bungarus; Carotid Stenosis; Chlorides; Disease Models, Animal; Dose-Response Relationship, Drug; Factor Xa Inhibitors; Factor XIa; Ferric Compounds; Humans; Kinetics; Male; Mice, Inbred C57BL; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Partial Thromboplastin Time; Protein Conformation; Prothrombin Time; Recombinant Proteins; Structure-Activity Relationship; Thrombosis | 2015 |
Defective thrombus formation in mice lacking endogenous factor VII activating protease (FSAP).
Topics: Animals; Blood Coagulation Tests; Carotid Arteries; Carotid Artery Diseases; Chlorides; Collagen; Disease Models, Animal; Ferric Compounds; Genetic Predisposition to Disease; Hemostasis; Jugular Veins; Lipoproteins; Mesenteric Arteries; Mesenteric Vascular Occlusion; Mice, Inbred C57BL; Mice, Knockout; Norepinephrine; Phenotype; Serine Endopeptidases; Thrombosis; Venous Thromboembolism | 2015 |
A plasmin-activatable thrombin inhibitor reduces experimental thrombosis and assists experimental thrombolysis in murine models.
Topics: Animals; Chlorides; Disease Models, Animal; Ferric Compounds; Hirudins; Humans; Mice; Rabbits; Recombinant Proteins; Thrombolytic Therapy; Thrombosis | 2015 |
Extracellular cyclophilin A activates platelets via EMMPRIN (CD147) and PI3K/Akt signaling, which promotes platelet adhesion and thrombus formation in vitro and in vivo.
Topics: Animals; Basigin; Blood Platelets; Carotid Artery Injuries; Cell Degranulation; Chlorides; Cyclophilin A; Disease Models, Animal; Dose-Response Relationship, Drug; Ferric Compounds; Fibrinolytic Agents; Humans; Mice, Inbred C57BL; Mice, Knockout; Phosphatidylinositol 3-Kinases; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Proto-Oncogene Proteins c-akt; Signal Transduction; Thrombosis; Time Factors | 2015 |
Kaempferol suppresses collagen-induced platelet activation by inhibiting NADPH oxidase and protecting SHP-2 from oxidative inactivation.
Topics: Agammaglobulinaemia Tyrosine Kinase; Animals; Chlorides; Collagen; Ferric Compounds; Humans; Intracellular Signaling Peptides and Proteins; Kaempferols; Male; Mice; Mice, Inbred C57BL; NADPH Oxidases; Oxidation-Reduction; Phospholipase C gamma; Phosphorylation; Platelet Activation; Platelet Aggregation; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-vav; Reactive Oxygen Species; Signal Transduction; Syk Kinase; Thrombosis | 2015 |
Arterial thrombosis is accelerated in mice deficient in histidine-rich glycoprotein.
Topics: Animals; Blood Coagulation; Chlorides; Factor XII; Female; Ferric Compounds; Gene Deletion; Gene Knockdown Techniques; Hemostasis; Mice; Mice, Inbred C57BL; Proteins; Thrombin; Thrombosis | 2015 |
Titrating haemophilia B phenotypes using siRNA strategy: evidence that antithrombotic activity is separated from bleeding liability.
Topics: Animals; Cell Line; Chlorides; Disease Models, Animal; Factor IX; Ferric Compounds; Gene Expression Regulation; Genotype; Hemophilia B; Hemorrhage; Hemostasis; Liver; Male; Phenotype; Rats; Rats, Sprague-Dawley; Rats, Transgenic; RNA Interference; RNA, Messenger; RNA, Small Interfering; RNAi Therapeutics; Thrombosis; Time Factors; Transfection | 2015 |
Resolving the multifaceted mechanisms of the ferric chloride thrombosis model using an interdisciplinary microfluidic approach.
Topics: Aspirin; Biomechanical Phenomena; Blood Platelets; Cell Aggregation; Chlorides; Erythrocytes; Ferric Compounds; Fibrinolytic Agents; Heparin; Humans; Microfluidic Analytical Techniques; Models, Biological; Platelet-Rich Plasma; Primary Cell Culture; Protein Aggregates; Protein Binding; Static Electricity; Thrombosis | 2015 |
Novel anti-thrombotic agent for modulation of protein disulfide isomerase family member ERp57 for prophylactic therapy.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Cell Adhesion Molecules; Chlorides; Disease Models, Animal; Enzyme Activation; Ferric Compounds; Fibrinolytic Agents; Gene Expression Regulation; Heme Oxygenase-1; Humans; Lactates; Microfilament Proteins; Models, Biological; P-Selectin; Phosphoproteins; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Protein Disulfide-Isomerases; Proteomics; Rats; Thrombosis; Venous Thrombosis | 2015 |
Ferric Chloride-induced Thrombosis Mouse Model on Carotid Artery and Mesentery Vessel.
Topics: Animals; Carotid Artery Thrombosis; Chlorides; Disease Models, Animal; Ferric Compounds; Male; Mesentery; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Thrombosis | 2015 |
Factor XII full and partial null in rat confers robust antithrombotic efficacy with no bleeding.
Topics: Animals; Arteriovenous Shunt, Surgical; Chlorides; Disease Models, Animal; Dose-Response Relationship, Drug; Ellagic Acid; Endodeoxyribonucleases; Factor XII; Ferric Compounds; Gene Knockout Techniques; Hemorrhage; Humans; Liver; Male; Partial Thromboplastin Time; Rats; Rats, Sprague-Dawley; RNA, Messenger; RNA, Small Interfering; Thrombin; Thrombolytic Therapy; Thrombosis; Zinc Fingers | 2015 |
Leukemia-associated Rho guanine-nucleotide exchange factor is not critical for RhoA regulation, yet is important for platelet activation and thrombosis in mice.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Blood Platelets; Cell Degranulation; Chlorides; Crosses, Genetic; Ferric Compounds; Gene Knockout Techniques; Mice; Mice, Knockout; Oligopeptides; Organ Specificity; Platelet Activation; Platelet Aggregation; rho GTP-Binding Proteins; Rho Guanine Nucleotide Exchange Factors; rhoA GTP-Binding Protein; Thrombosis | 2015 |
Small molecule PZL318: forming fluorescent nanoparticles capable of tracing their interactions with cancer cells and activated platelets, slowing tumor growth and inhibiting thrombosis.
Topics: Animals; Blood Platelets; Carbolines; Cell Line, Tumor; Cell Proliferation; Chlorides; Circular Dichroism; Dipeptides; Ferric Compounds; Fluorescent Dyes; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred ICR; Microscopy, Atomic Force; Microscopy, Confocal; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Nanoparticles; Neoplasms; Rats; Rats, Sprague-Dawley; Spectroscopy, Fourier Transform Infrared; Thrombosis; Viscosity | 2015 |
CD44 sensitivity of platelet activation, membrane scrambling and adhesion under high arterial shear rates.
Topics: Animals; Apoptosis; Blood Coagulation; Blood Platelets; Calcium Channels; Calcium Signaling; Caspase 3; Cell Degranulation; Cell Membrane; Chlorides; Disease Models, Animal; Female; Ferric Compounds; Genotype; Hyaluronan Receptors; Male; Mechanotransduction, Cellular; Mice, Knockout; ORAI1 Protein; Phenotype; Phospholipids; Platelet Adhesiveness; Platelet Glycoprotein GPIIb-IIIa Complex; Regional Blood Flow; Selenoprotein P; Stress, Mechanical; Thrombin; Thrombosis | 2016 |
Deubiquitinases Modulate Platelet Proteome Ubiquitination, Aggregation, and Thrombosis.
Topics: Aminopyridines; Animals; Benzoates; Blood Platelets; Chlorides; Disease Models, Animal; Enzyme Inhibitors; Ferric Compounds; Furans; Humans; Mice, Inbred C57BL; Microfluidic Analytical Techniques; Microscopy, Interference; Piperidones; Platelet Aggregation; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Proteasome Endopeptidase Complex; Pyrazoles; Receptors, Collagen; Receptors, Thrombin; Signal Transduction; Thiocyanates; Thrombosis; Ubiquitin Thiolesterase; Ubiquitin-Specific Proteases; Ubiquitination | 2015 |
Prevention of occlusive arterial thrombus formation by a single loading dose of prasugrel suppresses neointimal hyperplasia in mice.
Topics: Adenosine Diphosphate; Animals; Aorta; Arterial Occlusive Diseases; Arteries; Carotid Arteries; Chemokine CCL2; Chlorides; Ferric Compounds; Hyperplasia; Inflammation; Intercellular Adhesion Molecule-1; Mice; Mice, Inbred C57BL; Neointima; Platelet Aggregation; Prasugrel Hydrochloride; Pyridines; RNA, Messenger; Thrombosis; Time Factors; Transforming Growth Factor beta1 | 2015 |
Ferric chloride thrombosis model: unraveling the vascular effects of a highly corrosive oxidant.
Topics: Animals; Caustics; Chlorides; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Erythrocyte Aggregation; Erythrocytes; Ferric Compounds; Mice; Oxidants; Platelet Activation; Thrombosis | 2015 |
Misshapen/NIK-related kinase (MINK1) is involved in platelet function, hemostasis, and thrombus formation.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Chlorides; Ferric Compounds; MAP Kinase Signaling System; Mice; Mice, Knockout; p38 Mitogen-Activated Protein Kinases; Platelet Activation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Thrombosis | 2016 |
Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk.
Topics: Animals; Blood Platelets; Calcium; Carotid Artery Injuries; Cecum; Chlorides; Choline; Diet; Female; Ferric Compounds; Gastrointestinal Microbiome; Germ-Free Life; Humans; Methylamines; Mice; Mice, Inbred C57BL; Thrombosis | 2016 |
Hydrogen sulfide attenuates ferric chloride-induced arterial thrombosis in rats.
Topics: Animals; Chlorides; Ferric Compounds; Hydrogen Sulfide; Male; Mice; Mice, Inbred C57BL; Rats; Signal Transduction; Thrombosis | 2016 |
Heparanase expression upregulates platelet adhesion activity and thrombogenicity.
Topics: Animals; Blood Platelets; Carotid Arteries; Cell Separation; Chlorides; Crosses, Genetic; Erythrocytes; Female; Ferric Compounds; Flow Cytometry; Gene Expression Regulation; Glucuronidase; Glycosaminoglycans; Heparitin Sulfate; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; P-Selectin; Platelet Activation; Platelet Adhesiveness; Selenoprotein P; Thrombosis; Up-Regulation | 2016 |
Role of the CD39/CD73 Purinergic Pathway in Modulating Arterial Thrombosis in Mice.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Arterial Occlusive Diseases; Blood Coagulation; Bone Marrow Transplantation; Chlorides; Disease Models, Animal; Endothelial Cells; Ferric Compounds; Genetic Predisposition to Disease; HEK293 Cells; Humans; Hydrolysis; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Monocytes; Phenotype; Platelet Activation; Thrombosis; Time Factors; Transfection | 2016 |
Endothelial Cell-Derived von Willebrand Factor Is the Major Determinant That Mediates von Willebrand Factor-Dependent Acute Ischemic Stroke by Promoting Postischemic Thrombo-Inflammation.
Topics: ADAMTS13 Protein; Animals; Blood Platelets; Bone Marrow Transplantation; Carotid Artery Diseases; Chlorides; Disease Models, Animal; Endothelial Cells; Ferric Compounds; Genetic Predisposition to Disease; Infarction, Middle Cerebral Artery; Inflammation; Inflammation Mediators; Lasers; Male; Mesenteric Vascular Occlusion; Mice, Inbred C57BL; Mice, Knockout; Neutrophil Infiltration; Phenotype; Platelet Transfusion; Reperfusion Injury; Signal Transduction; Thrombosis; Time Factors; von Willebrand Factor | 2016 |
Characterization of the Anticoagulant and Antithrombotic Properties of the Sphingosine 1-Phosphate Mimetic FTY720.
Topics: Adenosine Diphosphate; Animals; Anticoagulants; Arteriovenous Shunt, Surgical; Biomimetic Materials; Blood Platelets; Carotid Artery, Common; Chlorides; Disease Models, Animal; Ferric Compounds; Fibrinolytic Agents; Fingolimod Hydrochloride; Humans; Lysophospholipids; Male; Platelet Aggregation; Platelet Function Tests; Rats; Rats, Sprague-Dawley; Receptors, Lysosphingolipid; Sphingosine; Thrombosis; Vena Cava, Inferior | 2017 |
Monascus Adlay and Monacolin K Attenuates Arterial Thrombosis in Rats through the Inhibition of ICAM-1 and Oxidative Stress.
Topics: Animals; Carotid Arteries; Chlorides; Ferric Compounds; Intercellular Adhesion Molecule-1; Lovastatin; Monascus; Oxidative Stress; Plant Extracts; Rats; Thrombosis | 2016 |
Xanthohumol isolated from Humulus lupulus prevents thrombosis without increased bleeding risk by inhibiting platelet activation and mtDNA release.
Topics: Animals; Antioxidants; Beer; Carotid Arteries; Cell Adhesion Molecules; Chlorides; Dendritic Cells; DNA, Mitochondrial; Ferric Compounds; Fibrinolytic Agents; Flavonoids; Hemorrhage; Humans; Humulus; Lectins, C-Type; Mice; Mice, Inbred C57BL; Platelet Activation; Platelet Aggregation Inhibitors; Propiophenones; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Cell Surface; Risk; Sirtuin 1; Thrombosis | 2017 |
Store-operated Ca(2+) entry in platelets occurs independently of transient receptor potential (TRP) C1.
Topics: Animals; Blood Coagulation; Blood Platelets; Calcium; Calcium Signaling; Chlorides; Disease Models, Animal; Ferric Compounds; Humans; Membrane Proteins; Mice; Mice, Knockout; Neoplasm Proteins; Platelet Activation; Stromal Interaction Molecule 1; Thrombosis; Time Factors; TRPC Cation Channels | 2008 |
Restoration of plasma von Willebrand factor deficiency is sufficient to correct thrombus formation after gene therapy for severe von Willebrand disease.
Topics: alpha 1-Antitrypsin; Animals; Bleeding Time; Chlorides; Cytomegalovirus; Disease Models, Animal; Factor VIII; Feasibility Studies; Ferric Compounds; Gene Transfer Techniques; Genetic Therapy; Humans; Liver; Mice; Mice, Knockout; Platelet Adhesiveness; Platelet Aggregation; Promoter Regions, Genetic; Severity of Illness Index; Thrombosis; Time Factors; von Willebrand Diseases; von Willebrand Factor | 2008 |
Salsolinol, an endogenous neurotoxin, enhances platelet aggregation and thrombus formation.
Topics: Adrenergic Antagonists; Animals; Blood Platelets; Cell Survival; Chlorides; Cyclic AMP; Disease Models, Animal; Dose-Response Relationship, Drug; Ferric Compounds; Humans; Isoquinolines; Male; Neurotoxins; P-Selectin; Platelet Aggregation; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Serotonin; Thrombosis; Time Factors | 2008 |
Deficiency of LRP8 in mice is associated with altered platelet function and prolonged time for in vivo thrombosis.
Topics: Animals; Apolipoprotein E3; Blood Platelets; Chlorides; Ferric Compounds; Humans; LDL-Receptor Related Proteins; Mice; Mice, Knockout; Nitric Oxide; Platelet Activation; Receptors, Lipoprotein; Thrombosis | 2009 |
Vascular smooth muscle-derived tissue factor is critical for arterial thrombosis after ferric chloride-induced injury.
Topics: Animals; Aorta; Carotid Artery Thrombosis; Chlorides; Enzyme-Linked Immunosorbent Assay; Female; Ferric Compounds; Fibrosis; Immunohistochemistry; Male; Mice; Mice, Mutant Strains; Muscle, Smooth, Vascular; Myocardium; Myocytes, Smooth Muscle; Noxae; Reverse Transcriptase Polymerase Chain Reaction; Thromboplastin; Thrombosis | 2009 |
Antithrombotic effects due to pharmacological modulation of thrombin-activatable fibrinolysis inhibitor in rats.
Topics: Animals; Bleeding Time; Blood Coagulation Tests; Carboxypeptidase B2; Chlorides; Disease Models, Animal; Dose-Response Relationship, Drug; Ferric Compounds; Fibrinolytic Agents; Injections, Intravenous; Male; Partial Thromboplastin Time; Plant Proteins; Protease Inhibitors; Prothrombin Time; Rats; Rats, Wistar; Thrombosis; Tissue Plasminogen Activator | 2008 |
Characterization of calcium- and integrin-binding protein 1 (CIB1) knockout platelets: potential compensation by CIB family members.
Topics: Animals; Binding Sites; Blood Platelets; Calcium-Binding Proteins; Cells, Cultured; Chlorides; Disease Models, Animal; Ferric Compounds; Hydrophobic and Hydrophilic Interactions; Megakaryocytes; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Molecular; Phenotype; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoprotein IIb; Protein Conformation; Recombinant Proteins; RNA, Messenger; Thrombosis; Time Factors | 2008 |
Platelet P2Y(12) receptor influences the vessel wall response to arterial injury and thrombosis.
Topics: Animals; Atherosclerosis; Blood Platelets; Bone Marrow Transplantation; Chlorides; Disease Models, Animal; Female; Femoral Artery; Ferric Compounds; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Muscle, Smooth, Vascular; Noxae; P-Selectin; Platelet Aggregation; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Thrombosis; Tunica Intima | 2009 |
The distal carboxyl-terminal domains of ADAMTS13 are required for regulation of in vivo thrombus formation.
Topics: ADAMTS13 Protein; Animals; Arterioles; Chlorides; Ferric Compounds; Metalloendopeptidases; Mice; Mice, Inbred Strains; Protein Structure, Tertiary; Thrombocytopenia; Thrombosis; von Willebrand Factor | 2009 |
Nicorandil attenuates FeCl(3)-induced thrombus formation through the inhibition of reactive oxygen species production.
Topics: Animals; Anti-Arrhythmia Agents; Arteries; Cells, Cultured; Chlorides; Collagen; Decanoic Acids; Endothelium, Vascular; Enzyme Inhibitors; Ferric Compounds; Humans; Hydroxy Acids; Isosorbide Dinitrate; Male; Mice; Mice, Inbred ICR; Mitochondria; NG-Nitroarginine Methyl Ester; Nicorandil; Nitric Oxide Synthase Type III; Oxidative Stress; Platelet Aggregation; Potassium Channels; Reactive Oxygen Species; Thrombosis; Umbilical Veins; Vasodilator Agents | 2009 |
Autoantibodies to heat shock protein 60 promote thrombus formation in a murine model of arterial thrombosis.
Topics: Animals; Arterial Occlusive Diseases; Autoantibodies; Carotid Artery Diseases; Chaperonin 60; Chlorides; Disease Models, Animal; Ferric Compounds; Mice; P-Selectin; Regional Blood Flow; Reperfusion; Thrombosis; von Willebrand Factor | 2009 |
Erythrocyte hemolysis and hemoglobin oxidation promote ferric chloride-induced vascular injury.
Topics: Animals; Aorta; Chlorides; Endothelium, Vascular; Erythrocytes; Female; Ferric Compounds; Fibrinolytic Agents; Fluorescent Antibody Technique; Hemoglobins; Hemolysis; Lipid Peroxidation; Male; Mice; Mice, Inbred C57BL; Noxae; Oxidation-Reduction; Thrombosis | 2009 |
Renal and cardiovascular characterization of COX-2 knockdown mice.
Topics: Animals; Blood Pressure; Blood Urea Nitrogen; Cardiovascular System; Cells, Cultured; Chlorides; Cyclooxygenase 1; Cyclooxygenase 2; Cytokines; Dinoprostone; Disease Models, Animal; Endothelial Cells; Epoprostenol; Ferric Compounds; Glomerular Filtration Rate; Heart Rate; Kidney; Macrophages, Peritoneal; Membrane Proteins; Mice; Mice, Knockout; Microscopy, Video; Thrombosis; Thromboxane B2; Time Factors | 2009 |
Prothrombotic effects of diclofenac on arteriolar platelet activation and thrombosis in vivo.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arterioles; Cells, Cultured; Chlorides; Cricetinae; Cyclooxygenase Inhibitors; Diclofenac; Endothelium, Vascular; Ferric Compounds; Humans; Mesocricetus; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Platelet Activation; Platelet Adhesiveness; Skin Window Technique; Thromboplastin; Thrombosis; Thromboxane B2; Tumor Necrosis Factor-alpha | 2009 |
A platelet tetraspanin superfamily member, CD151, is required for regulation of thrombus growth and stability in vivo.
Topics: Animals; Antigens, CD; Arterioles; Blood Platelets; Chlorides; Endothelium; Ferric Compounds; Mice; Mice, Knockout; Microscopy; Splanchnic Circulation; Tetraspanin 24; Thrombosis | 2009 |
A ferric chloride induced arterial injury model used as haemostatic effect model.
Topics: Animals; Carotid Artery Diseases; Chlorides; Disease Models, Animal; Dose-Response Relationship, Drug; Factor IX; Factor VIII; Ferric Compounds; Hemophilia A; Hemostasis; Mice; Mice, Knockout; Recombinant Proteins; Thrombosis | 2010 |
Imaging of structural changes in endothelial cells and thrombus formation at the site of FeCl(3)-induced injuries in mice cremasteric arteries.
Topics: Animals; Arteries; Aspirin; Blood Platelets; Chlorides; Clopidogrel; Dose-Response Relationship, Drug; Endothelial Cells; Ferric Compounds; Leukocytes; Male; Mice; Mice, Inbred ICR; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine | 2009 |
Deletion of the p110beta isoform of phosphoinositide 3-kinase in platelets reveals its central role in Akt activation and thrombus formation in vitro and in vivo.
Topics: Animals; Bleeding Time; Blood Platelets; Cell Lineage; Cells, Cultured; Chlorides; Class I Phosphatidylinositol 3-Kinases; Disease Models, Animal; Enzyme Activation; Ferric Compounds; Gene Deletion; Genetic Predisposition to Disease; Isoenzymes; Megakaryocytes; Mice; Mice, Transgenic; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Platelet Aggregation; Thrombosis | 2010 |
Mutation-specific hemostatic variability in mice expressing common type 2B von Willebrand disease substitutions.
Topics: Amino Acid Substitution; Animals; Blood Platelets; Chlorides; Disease Models, Animal; Ferric Compounds; Humans; Integrin alpha2; Mice; Mice, Knockout; Mutation, Missense; Noxae; Platelet Adhesiveness; Thrombocytopenia; Thrombosis; von Willebrand Disease, Type 2; von Willebrand Factor | 2010 |
Enhanced platelet reactivity and thrombosis in Apoe-/- mice exposed to cigarette smoke is attenuated by P2Y12 antagonism.
Topics: Adenosine Monophosphate; Animals; Apolipoproteins E; Blood Platelets; Chlorides; Female; Ferric Compounds; Fibrinogen; Gene Deletion; Mice; Mice, Inbred C57BL; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Thrombosis; Tobacco Smoke Pollution | 2010 |
AMPK α2 subunit is involved in platelet signaling, clot retraction, and thrombus stability.
Topics: AMP-Activated Protein Kinases; Animals; Blood Platelets; Chlorides; Clot Retraction; Ferric Compounds; Humans; Mice; Phosphorylation; Platelet Glycoprotein GPIIb-IIIa Complex; Proto-Oncogene Proteins c-fyn; Signal Transduction; Thrombosis | 2010 |
In vivo models for the evaluation of antithrombotics and thrombolytics.
Topics: Animals; Cardiopulmonary Bypass; Chlorides; Constriction, Pathologic; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Electricity; Female; Ferric Compounds; Fibrinolytic Agents; Foreign Bodies; Hematologic Diseases; Hemostasis; Humans; Lasers; Male; Mice; Models, Genetic; Photochemical Processes; Rabbits; Rats; Stress, Mechanical; Thrombin; Thrombosis | 2010 |
Evaluation of AR-H067637, the active metabolite of the new direct thrombin inhibitor AZD0837, in models of venous and arterial thrombosis and bleeding in anaesthetised rats.
Topics: Amidines; Animals; Antithrombin III; Antithrombins; Azetidines; Blood Coagulation; Chlorides; Dalteparin; Disease Models, Animal; Dose-Response Relationship, Drug; Ferric Compounds; Fibrinolytic Agents; Hemorrhage; Infusions, Intravenous; Male; Partial Thromboplastin Time; Peptide Hydrolases; Prodrugs; Rats; Rats, Sprague-Dawley; Thrombin; Thrombin Time; Thrombosis; Venous Thrombosis | 2010 |
Platelets enhance lymphocyte adhesion and infiltration into arterial thrombus.
Topics: Adult; Animals; Antibodies, Monoclonal; Arterioles; B-Lymphocytes; Blood Platelets; CD40 Ligand; Chlorides; Collagen; Disease Models, Animal; Female; Ferric Compounds; Humans; Killer Cells, Natural; Leukocyte Rolling; Male; Mesentery; Mice; Mice, Inbred C57BL; Middle Aged; P-Selectin; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Stress, Mechanical; T-Lymphocytes; Thrombosis; Time Factors; Young Adult | 2010 |
Deletion of the high-density lipoprotein receptor scavenger receptor BI in mice modulates thrombosis susceptibility and indirectly affects platelet function by elevation of plasma free cholesterol.
Topics: Animals; Arterial Occlusive Diseases; Blood Platelets; Bone Marrow Transplantation; Chlorides; Cholesterol, Dietary; Cholesterol, HDL; Disease Models, Animal; Ferric Compounds; Fibrinogen; Mice; Mice, Knockout; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation; Scavenger Receptors, Class B; Thrombocytopenia; Thrombosis; Time Factors; Up-Regulation | 2011 |
Mechanisms underlying FeCl3-induced arterial thrombosis.
Topics: Animals; Anticoagulants; Carotid Arteries; Chlorides; Disease Models, Animal; Ferric Compounds; Mice; Mice, Inbred C57BL; Microscopy, Electron, Scanning; Platelet Aggregation Inhibitors; Thrombosis; Vascular Diseases | 2011 |
Thrombotic distal middle cerebral artery occlusion produced by topical FeCl(3) application: a novel model suitable for intravital microscopy and thrombolysis studies.
Topics: Administration, Topical; Animals; Chlorides; Ferric Compounds; Infarction, Middle Cerebral Artery; Mice; Mice, Inbred C57BL; Microscopy; Middle Cerebral Artery; Models, Animal; Thrombosis; Tissue Plasminogen Activator | 2011 |
Causal relationship between hyperfibrinogenemia, thrombosis, and resistance to thrombolysis in mice.
Topics: Animals; Carotid Artery Thrombosis; Chlorides; Disease Models, Animal; Drug Resistance; Ferric Compounds; Fibrinogen; Fibrinolytic Agents; Humans; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Platelet Aggregation; Risk Factors; Saphenous Vein; Thrombolytic Therapy; Thrombosis | 2011 |
A ride with ferric chloride.
Topics: Animals; Chlorides; Ferric Compounds; Humans; Mice; Thrombosis | 2011 |
In vivo fluorescence imaging of large-vessel thrombosis in mice.
Topics: Animals; Blood Coagulation Factors; Blood Platelets; Chlorides; Ferric Compounds; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Thrombosis | 2011 |
Evaluation of anti-platelet and anti-thrombotic effects of cilostazol with PFA-100® and Multiplate® whole blood aggregometer in vitro, ex vivo and FeCl3-induced thrombosis models in vivo.
Topics: Animals; Blood Platelets; Chlorides; Cilostazol; Ferric Compounds; Fibrinolytic Agents; Male; Mice; Mice, Inbred C57BL; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Rats; Rats, Sprague-Dawley; Tetrazoles; Thrombosis | 2011 |
Genetic and antibody-induced glycoprotein VI deficiency equally protects mice from mechanically and FeCl(3) -induced thrombosis.
Topics: Animals; Antibodies; Chlorides; Ferric Compounds; Mechanical Phenomena; Mice; Platelet Membrane Glycoproteins; Protective Agents; Thrombosis | 2011 |
Inducible nitric oxide synthase provides protection against injury-induced thrombosis in female mice.
Topics: Analysis of Variance; Animals; Aorta; Blood Coagulation; Cardiomegaly; Carotid Arteries; Carotid Artery Injuries; Chlorides; Disease Models, Animal; Estradiol; Female; Ferric Compounds; Interferon-gamma; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type II; Regional Blood Flow; Sex Factors; Thrombosis; Time Factors | 2011 |
Enzymatic single-chain antibody tagging: a universal approach to targeted molecular imaging and cell homing in cardiovascular disease.
Topics: Aminoacyltransferases; Animals; Bacterial Proteins; Blood Platelets; Cell Movement; Cell Tracking; Chlorides; CHO Cells; Contrast Media; Cricetinae; Cricetulus; Cysteine Endopeptidases; Disease Models, Animal; Ferric Compounds; Flow Cytometry; Green Fluorescent Proteins; Humans; Magnetic Resonance Imaging; Magnetite Nanoparticles; Mice; Mice, Inbred C57BL; Microscopy, Video; Molecular Probe Techniques; Platelet Activation; Recombinant Fusion Proteins; Single-Chain Antibodies; Thrombosis | 2011 |
Essential domains of a disintegrin and metalloprotease with thrombospondin type 1 repeats-13 metalloprotease required for modulation of arterial thrombosis.
Topics: ADAM Proteins; ADAMTS13 Protein; Animals; Antibodies, Monoclonal; Carotid Stenosis; Chlorides; Disease Models, Animal; Dogs; Ferric Compounds; Half-Life; HEK293 Cells; Humans; Kinetics; Mesenteric Vascular Occlusion; Metalloendopeptidases; Mice; Mice, Knockout; Mutagenesis, Site-Directed; Mutation; Protein Structure, Tertiary; Recombinant Proteins; Structure-Activity Relationship; Thrombosis; Transfection; von Willebrand Factor | 2011 |
Procoagulant activity induced by vascular injury determines contribution of elevated factor VIII to thrombosis and thrombus stability in mice.
Topics: Animals; Antithrombin III; Carotid Artery Injuries; Cells, Cultured; Chlorides; Factor VIII; Ferric Compounds; Humans; Male; Mice; Mice, Inbred C57BL; Peptide Hydrolases; Platelet Aggregation; Thrombin; Thromboplastin; Thrombosis; Vascular System Injuries | 2011 |
Diminished thrombogenic responses by deletion of the Podocalyxin Gene in mouse megakaryocytes.
Topics: Animals; Blood Coagulation; Blood Platelets; Carotid Arteries; Cell Count; Chlorides; Ferric Compounds; Gene Deletion; Hemorrhage; Megakaryocytes; Mice; Mice, Inbred C57BL; Platelet Adhesiveness; Platelet Aggregation; Sialoglycoproteins; Thrombosis | 2011 |
An antithrombotic fucoidan, unlike heparin, does not prolong bleeding time in a murine arterial thrombosis model: a comparative study of Undaria pinnatifida sporophylls and Fucus vesiculosus.
Topics: Animals; Anticoagulants; Bleeding Time; Chlorides; Disease Models, Animal; Ferric Compounds; Fibrinolytic Agents; Fucus; Heparin; Injections, Intravenous; Male; Mice; Mice, Inbred BALB C; Polysaccharides; Thrombosis; Undaria | 2012 |
Defective diacylglycerol-induced Ca2+ entry but normal agonist-induced activation responses in TRPC6-deficient mouse platelets.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; C-Reactive Protein; Calcium Channels; Calcium Signaling; Chlorides; Diglycerides; Disease Models, Animal; Ferric Compounds; Gene Expression Regulation; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; ORAI1 Protein; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; RNA, Messenger; Secretory Vesicles; Stromal Interaction Molecule 1; Thrombin; Thrombosis; Time Factors; TRPC Cation Channels; TRPC6 Cation Channel | 2012 |
Identification of galectin-1 and galectin-3 as novel partners for von Willebrand factor.
Topics: Animals; Cells, Cultured; Chlorides; Disease Models, Animal; Ferric Compounds; Galectin 1; Galectin 3; Human Umbilical Vein Endothelial Cells; Humans; Immunoprecipitation; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Fluorescence; Platelet Adhesiveness; Protein Binding; Protein Interaction Domains and Motifs; Protein Interaction Mapping; Thrombosis; Time Factors; von Willebrand Factor | 2012 |
Reduction of thrombus size in murine models of thrombosis following administration of recombinant α1-proteinase inhibitor mutant proteins.
Topics: alpha 1-Antitrypsin; Animals; Antithrombins; Carotid Artery Injuries; Chlorides; Disease Models, Animal; Dose-Response Relationship, Drug; Endotoxemia; Endotoxins; Factor Xa; Factor Xa Inhibitors; Factor XIa; Factor XIIa; Ferric Compounds; Fibrinogen; Fibrinolytic Agents; Hemorrhage; Injections, Intravenous; Kinetics; Leukocyte Elastase; Mice; Mutation; NG-Nitroarginine Methyl Ester; Recombinant Fusion Proteins; Thrombin; Thrombosis | 2012 |
Use of a mouse model to elucidate the phenotypic effects of the von Willebrand factor cleavage mutants, Y1605A/M1606A and R1597W.
Topics: ADAMTS13 Protein; Animals; Blood Coagulation; Blotting, Western; Chlorides; Disease Models, Animal; Ferric Compounds; Gene Transfer Techniques; Genotype; HEK293 Cells; Humans; Infusions, Intravenous; Injections, Intravenous; Metalloendopeptidases; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Weight; Mutagenesis, Site-Directed; Mutation; Phenotype; Platelet Activation; Protein Multimerization; Recombinant Proteins; Thrombosis; Time Factors; Transfection; von Willebrand Diseases; von Willebrand Factor | 2012 |
Effects of plasma kallikrein deficiency on haemostasis and thrombosis in mice: murine ortholog of the Fletcher trait.
Topics: Animals; Bleeding Time; Chlorides; Disease Models, Animal; Ferric Compounds; Hemorrhage; Hemostasis; Heterozygote; Mice; Mice, Knockout; Oligonucleotides, Antisense; Partial Thromboplastin Time; Phenotype; Plasma Kallikrein; Prekallikrein; Thrombosis; Time Factors; Venous Thrombosis | 2012 |
The mouse dorsal skinfold chamber as a model for the study of thrombolysis by intravital microscopy.
Topics: Animals; Chlorides; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Ferric Compounds; Fibrinolysis; Fibrinolytic Agents; Hemorrhage; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Fluorescence; Plasminogen Activator Inhibitor 1; Recombinant Proteins; Skin; Thrombolytic Therapy; Thrombosis; Time Factors; Tissue Plasminogen Activator | 2012 |
Cationic derivative of dextran reverses anticoagulant activity of unfractionated heparin in animal models of arterial and venous thrombosis.
Topics: Animals; Anticoagulants; Bleeding Time; Blood Coagulation; Chlorides; Dextrans; Disease Models, Animal; Ferric Compounds; Heparin; Heparin Antagonists; Male; Mice; Partial Thromboplastin Time; Platelet Aggregation; Protamines; Rats; Rats, Wistar; Thrombosis | 2012 |
Lufaxin, a novel factor Xa inhibitor from the salivary gland of the sand fly Lutzomyia longipalpis blocks protease-activated receptor 2 activation and inhibits inflammation and thrombosis in vivo.
Topics: Amino Acid Sequence; Animals; Anti-Inflammatory Agents; Blood Coagulation; Calorimetry; Cell Line, Tumor; Chlorides; Cloning, Molecular; Disease Models, Animal; Dose-Response Relationship, Drug; Factor Xa; Factor Xa Inhibitors; Female; Ferric Compounds; Fibrinolytic Agents; HEK293 Cells; Humans; Inflammation; Insect Proteins; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Molecular Weight; Partial Thromboplastin Time; Protein Binding; Prothrombin Time; Psychodidae; Rats; Receptor, PAR-2; Recombinant Proteins; Salivary Glands; Surface Plasmon Resonance; Thromboplastin; Thrombosis; Time Factors | 2012 |
BF066, a novel dual target antiplatelet agent without significant bleeding.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Arterioles; Chlorides; Collagen; Ferric Compounds; Fibrinogen; Hemorrhage; Humans; Immobilized Proteins; Mice; Mice, Inbred C57BL; Oligopeptides; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptor, Adenosine A2A; Thrombin; Thrombosis | 2012 |
Increased platelet activation and thrombosis in transgenic mice expressing constitutively active P2Y12.
Topics: Adenosine Monophosphate; Animals; Bleeding Time; Blood Platelets; Chlorides; Cyclic AMP; Disease Models, Animal; Drug Inverse Agonism; Ferric Compounds; Fibrinolytic Agents; Genotype; Mice; Mice, Transgenic; Phenotype; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Proto-Oncogene Proteins c-akt; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Thrombosis | 2012 |
A murine model to characterize the antithrombotic effect of molecules targeting human von Willebrand factor.
Topics: ADAMTS13 Protein; Animals; Antibodies, Monoclonal; Chlorides; Collagen; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Ferric Compounds; Fibrinolytic Agents; Hemorrhage; Humans; Metalloendopeptidases; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutagenesis, Site-Directed; Mutation; Platelet Adhesiveness; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombosis; von Willebrand Factor | 2012 |
Altered microtubule equilibrium and impaired thrombus stability in mice lacking RanBP10.
Topics: Animals; Arteries; Blood Platelets; Chlorides; Collagen; Cytoplasmic Granules; Ferric Compounds; Gene Expression; Guanine Nucleotide Exchange Factors; Hemorheology; Mice; Mice, Knockout; Microtubule-Associated Proteins; Microtubules; Paclitaxel; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation; Polymerization; Protein Isoforms; Signal Transduction; Thrombosis; Tubulin; von Willebrand Factor | 2012 |
Oxidation inhibits iron-induced blood coagulation.
Topics: Adult; Blood Coagulation; Chlorides; Female; Ferric Compounds; Fibrin; Fibrinogen; Humans; Hydrogen Peroxide; Hydroxyl Radical; Methylene Blue; Microscopy, Electron, Scanning; Oxidants; Oxidation-Reduction; Sodium Selenite; Thrombosis; Young Adult | 2013 |
In vitro and in vivo evaluation of the effect of elevated factor VIII on the thrombogenic process.
Topics: Animals; Antithrombin III; Blood Coagulation; Chlorides; Disease Models, Animal; Factor VIII; Ferric Compounds; Hemophilia A; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptide Hydrolases; Thrombelastography; Thrombosis; Time Factors; Up-Regulation; Vascular System Injuries | 2013 |
GDF-15 prevents platelet integrin activation and thrombus formation.
Topics: Animals; Bleeding Time; Blood Platelets; Chlorides; Collagen; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Enzyme Activation; Ferric Compounds; Flow Cytometry; Growth Differentiation Factor 15; Hemostasis; Humans; Integrin beta1; Integrin beta3; Integrins; Mice; Mice, Inbred C57BL; Mice, Knockout; P-Selectin; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pulmonary Embolism; rap1 GTP-Binding Proteins; Recombinant Proteins; Thrombosis; Time Factors | 2013 |
Red blood cells mediate the onset of thrombosis in the ferric chloride murine model.
Topics: Animals; Cells, Cultured; Chlorides; Disease Models, Animal; Erythrocyte Aggregation; Erythrocytes; Ferric Compounds; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Platelet Adhesiveness; Receptors, Cell Surface; Thrombosis; von Willebrand Factor | 2013 |
Mice with a severe deficiency of the endothelial protein C receptor gene develop, survive, and reproduce normally, and do not present with enhanced arterial thrombosis after challenge.
Topics: Animals; Arteries; Blood Coagulation Factors; Chlorides; Embryonic and Fetal Development; Ferric Compounds; Immunohistochemistry; Mice; Mice, Mutant Strains; Receptors, Cell Surface; Reproduction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survival Rate; Thrombosis; Tissue Distribution | 2002 |
Protection against thrombosis in mice lacking PAR3.
Topics: Animals; Arterioles; Bleeding Time; Chlorides; Enzyme Activation; Female; Ferric Compounds; Genotype; Lung; Mesentery; Mice; Mice, Inbred C57BL; Mice, Knockout; Platelet Activation; Pulmonary Embolism; Receptors, Thrombin; Single-Blind Method; Thrombin; Thromboplastin; Thrombosis | 2002 |
Anti-thrombotic activity of PDR, a newly synthesized L-Arg derivative, on three thrombosis models in rats.
Topics: Adenosine Diphosphate; Animals; Arginine; Arteriovenous Shunt, Surgical; Autacoids; Chlorides; Collagen; Electric Stimulation; Ferric Compounds; Fibrinolytic Agents; Male; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Thrombin; Thrombosis | 2003 |
Cause-effect relation between hyperfibrinogenemia and vascular disease.
Topics: Animals; Carotid Arteries; Chlorides; Cross-Linking Reagents; Dimerization; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Ferric Compounds; Fibrinogen; Mice; Mice, Transgenic; Protein Binding; Thrombin; Thrombosis; Vascular Diseases | 2004 |
Vascular heme oxygenase-1 induction suppresses microvascular thrombus formation in vivo.
Topics: Animals; Antioxidants; Bilirubin; Chlorides; Chromans; Enzyme Induction; Enzyme Inhibitors; Ferric Compounds; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hemin; Male; Membrane Proteins; Metalloporphyrins; Mice; Mice, Inbred C57BL; Mice, Knockout; Microcirculation; Muscle, Skeletal; P-Selectin; Protoporphyrins; Thrombosis | 2004 |
Molecular imaging of factor XIIIa activity in thrombosis using a novel, near-infrared fluorescent contrast agent that covalently links to thrombi.
Topics: alpha-2-Antiplasmin; Animals; Chlorides; Contrast Media; Cross-Linking Reagents; Factor XIIIa; Feasibility Studies; Ferric Compounds; Fibrin; Fluorescent Dyes; Humans; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Peptide Fragments; Protein Binding; Spectroscopy, Near-Infrared; Thrombosis; Time Factors | 2004 |
In vitro and in vivo antithrombotic activity of PD-198961, a novel synthetic factor Xa inhibitor.
Topics: Animals; Bleeding Time; Chlorides; Dogs; Dose-Response Relationship, Drug; Factor Xa Inhibitors; Ferric Compounds; Fibrinolytic Agents; Humans; In Vitro Techniques; Injections, Intravenous; Partial Thromboplastin Time; Prothrombin Time; Quinoxalines; Rabbits; Species Specificity; Thrombosis; Time Factors | 2004 |
The combination of modified antioxidant enzymes for anti-thrombotic protection of the vascular wall: the significance of covalent connection of superoxide dismutase and catalase activities.
Topics: Animals; Antioxidants; Catalase; Chlorides; Chondroitin Sulfates; Disease Models, Animal; Ferric Compounds; Injections, Intravenous; Male; Rats; Structure-Activity Relationship; Superoxide Dismutase; Thrombosis | 2004 |
An optimized murine model of ferric chloride-induced arterial thrombosis for thrombosis research.
Topics: Animals; Arterial Occlusive Diseases; Carotid Artery Diseases; Chlorides; Clopidogrel; Disease Models, Animal; Dose-Response Relationship, Drug; Ferric Compounds; Heparin; Kinetics; Mice; Regional Blood Flow; Research; Thrombosis; Ticlopidine | 2005 |
Combined effects of a factor Xa inhibitor YM466 and a GPIIb/IIIa antagonist YM128 on thrombosis and neointima formation in mice.
Topics: Angioplasty; Animals; Bleeding Time; Blood Coagulation; Blood Platelets; Carotid Arteries; Carotid Artery Thrombosis; Chlorides; Dose-Response Relationship, Drug; Drug Synergism; Factor Xa; Factor Xa Inhibitors; Ferric Compounds; Mice; Mice, Inbred ICR; Naphthalenes; Piperazines; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prothrombin Time; Thrombosis; Time Factors | 2004 |
Role of p38 mitogen-activated protein kinase in thrombus formation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alleles; Animals; Blood Coagulation; Blood Platelets; Chlorides; Ferric Compounds; Fibrinogen; Heterozygote; Homozygote; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; p38 Mitogen-Activated Protein Kinases; Placenta; Platelet Adhesiveness; Protein Binding; Protein Isoforms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thromboplastin; Thrombosis; Thromboxane A2; Time Factors; Vasoconstrictor Agents | 2004 |
Effects of factor IX or factor XI deficiency on ferric chloride-induced carotid artery occlusion in mice.
Topics: Animals; Arteries; Aspirin; Bleeding Time; Blood Flow Velocity; Carotid Arteries; Carotid Artery Diseases; Chlorides; Dose-Response Relationship, Drug; Factor IX; Factor XI; Factor XI Deficiency; Ferric Compounds; Genotype; Hemophilia B; Heparin; Homozygote; Mice; Mice, Inbred C57BL; Platelet Aggregation; Regional Blood Flow; Thrombosis; Time Factors | 2005 |
Evaluation of two experimental venous thrombosis models in the rat.
Topics: Animals; Blood Coagulation Tests; Chlorides; Disease Models, Animal; Female; Ferric Compounds; Hemostasis; Male; Nadroparin; Rats; Rats, Wistar; Regression Analysis; Sensitivity and Specificity; Thromboplastin; Thrombosis; Venous Thrombosis | 2005 |
Pharmacological properties of YM-254890, a specific G(alpha)q/11 inhibitor, on thrombosis and neointima formation in mice.
Topics: Administration, Oral; Animals; Blood Pressure; Carotid Arteries; Cell Proliferation; Chlorides; Chromones; Clopidogrel; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ferric Compounds; GTP-Binding Protein alpha Subunits, Gq-G11; Heart Rate; Male; Mice; Mice, Inbred ICR; Models, Chemical; Morpholines; Muscle, Smooth; Muscle, Smooth, Vascular; Peptides, Cyclic; Platelet Aggregation; Thrombosis; Ticlopidine; Time Factors; Tunica Intima | 2005 |
Stimulatory roles of nitric-oxide synthase 3 and guanylyl cyclase in platelet activation.
Topics: Animals; Blood Platelets; Cells, Cultured; Chlorides; Ferric Compounds; Gene Expression Regulation, Enzymologic; Guanylate Cyclase; Humans; Mice; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Platelet Activation; Platelet Aggregation; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Thrombosis | 2005 |
Platelet PECAM-1 inhibits thrombus formation in vivo.
Topics: Animals; Blood Coagulation; Blood Platelets; Bone Marrow; Carotid Arteries; Chlorides; Female; Ferric Compounds; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Platelet Endothelial Cell Adhesion Molecule-1; Thrombosis; Time Factors | 2006 |
Thrombotic phenotype of mice with a combined deficiency in plasminogen activator inhibitor 1 and vitronectin.
Topics: Animals; Chlorides; Ferric Compounds; Mice; Mice, Knockout; Phenotype; Plasminogen Activator Inhibitor 1; Thrombosis; Time Factors; Vascular Patency; Vitronectin | 2005 |
Glycoprotein VI-dependent and -independent pathways of thrombus formation in vivo.
Topics: Animals; Chlorides; Ferric Compounds; Hirudins; Lasers; Mice; Mice, Knockout; Platelet Membrane Glycoproteins; Radionuclide Imaging; Receptors, IgG; Recombinant Proteins; Thrombosis | 2006 |
Plasminogen activator inhibitor-1 from bone marrow-derived cells suppresses neointimal formation after vascular injury in mice.
Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Carotid Arteries; Carotid Artery Diseases; Carotid Stenosis; Cell Differentiation; Chlorides; DNA; Female; Ferric Compounds; Macrophages; Mice; Mice, Knockout; Myocytes, Smooth Muscle; Plasminogen Activator Inhibitor 1; Thrombosis; Time Factors; Tunica Intima; Y Chromosome | 2006 |
Decreased plasma fibronectin leads to delayed thrombus growth in injured arterioles.
Topics: Alternative Splicing; Animals; Arterial Occlusive Diseases; Arterioles; Bleeding Time; Blood Coagulation; Blood Platelets; Chlorides; Ferric Compounds; Fibronectins; Haploidy; Heterozygote; Mice; Mice, Knockout; Platelet Adhesiveness; Protein Structure, Tertiary; Rats; Splanchnic Circulation; Thrombosis; Venules | 2006 |
P2X1 stimulation promotes thrombin receptor-mediated platelet aggregation.
Topics: Animals; Blood Platelets; Chlorides; Ferric Compounds; Humans; Lasers; Mice; Platelet Aggregation; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Thrombin; Species Specificity; Thrombosis | 2006 |
Conformation-specific blockade of the integrin GPIIb/IIIa: a novel antiplatelet strategy that selectively targets activated platelets.
Topics: Amino Acid Motifs; Animals; Antibodies; Bleeding Time; Blood Platelets; Carotid Artery Diseases; Chlorides; Complementarity Determining Regions; Eptifibatide; Ferric Compounds; Fibrinogen; Fibrinolytic Agents; Humans; Mice; Mice, Inbred C57BL; Molecular Conformation; Peptides; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombosis; Tirofiban; Tyrosine | 2006 |
Increased venous versus arterial thrombosis in the Factor V Leiden mouse.
Topics: Amino Acid Substitution; Animals; Arginine; Arterial Occlusive Diseases; Arteries; Chlorides; Disease Models, Animal; Factor V; Ferric Compounds; Gene Frequency; Glutamine; Homozygote; Mice; Mice, Inbred C57BL; Mutation; Thrombosis; Venous Thrombosis | 2007 |
Quantification of platelet composition in experimental venous thrombosis by real-time polymerase chain reaction.
Topics: Animals; Blood Platelets; Chemokine CCL2; Chlorides; Disease Models, Animal; Ferric Compounds; Gene Expression; Interleukin-1beta; Male; Microscopy, Electron; Nitric Oxide Synthase Type II; P-Selectin; Platelet Factor 4; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Saline Solution, Hypertonic; Thrombin; Thrombosis; Venae Cavae; Venous Thrombosis | 2007 |
Genetic strain differences in platelet aggregation and thrombus formation of laboratory rats.
Topics: Adenosine Diphosphate; Animals; Arteriovenous Shunt, Surgical; Bleeding Time; Blood Platelets; Chlorides; Collagen; Disease Models, Animal; Drug Evaluation, Preclinical; Ferric Compounds; Fibrinolytic Agents; Genetic Variation; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Inbred ACI; Rats, Inbred BN; Rats, Inbred F344; Rats, Inbred Lew; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Thrombin; Species Specificity; Thrombosis | 2007 |
Experimental arterial thrombosis regulated by androgen and its receptor via modulation of platelet activation.
Topics: 6-Ketoprostaglandin F1 alpha; Androgens; Animals; Arteries; Castration; Chlorides; Dihydrotestosterone; Ferric Compounds; Male; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation; Rats; Receptors, Androgen; Testosterone; Thrombosis; Thromboxane A2 | 2007 |
Diminished thrombus formation and alleviation of myocardial infarction and reperfusion injury through antibody- or small-molecule-mediated inhibition of selectin-dependent platelet functions.
Topics: Animals; Antibodies, Monoclonal; Arterial Occlusive Diseases; Chlorides; Drug Evaluation, Preclinical; Endothelial Cells; Ferric Compounds; Fibrinolytic Agents; Hemorheology; Humans; Immunoglobulin Fab Fragments; Macrolides; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Weight; Myocardial Infarction; Myocardial Reperfusion Injury; Neutrophils; Oligosaccharides; P-Selectin; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Inbred Lew; Sialyl Lewis X Antigen; Thrombosis | 2007 |
A recombinant protein and a chemically synthesized peptide containing the active peptides of the platelet collagen receptors inhibit ferric chloride-induced thrombosis in a rat model.
Topics: Animals; Base Sequence; Chlorides; Collagen Type I; Collagen Type III; DNA Primers; Ferric Compounds; Humans; In Vitro Techniques; Male; Peptides; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Collagen; Recombinant Proteins; Thrombosis | 2007 |
The antithrombotic potential of selective blockade of talin-dependent integrin alpha IIb beta 3 (platelet GPIIb-IIIa) activation.
Topics: Amino Acid Substitution; Anemia; Animals; Blood Platelets; Chlorides; Contractile Proteins; Ferric Compounds; Fibrinogen; Filamins; Hemorrhage; Homozygote; Mice; Mice, Transgenic; Microfilament Proteins; Platelet Glycoprotein GPIIb-IIIa Complex; Point Mutation; Protein Binding; Protein Structure, Tertiary; Pulmonary Embolism; Talin; Thrombosis | 2007 |
Factor V Leiden mutation is associated with enhanced arterial thrombotic tendency in lean but not in obese mice.
Topics: Animal Feed; Animals; Arteries; Body Weight; Chlorides; Factor V; Ferric Compounds; Genotype; Homozygote; Male; Mice; Mice, Obese; Mutation; Obesity; Plasminogen Activator Inhibitor 1; Thrombosis | 2007 |
Role of murine integrin alpha2beta1 in thrombus stabilization and embolization: contribution of thromboxane A2.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aspirin; Chlorides; Collagen; Ferric Compounds; Integrin alpha2beta1; Mice; Mice, Knockout; Thromboembolism; Thrombosis; Thromboxane A2 | 2007 |
Loss of talin1 in platelets abrogates integrin activation, platelet aggregation, and thrombus formation in vitro and in vivo.
Topics: Animals; Arterioles; Blood Platelets; Chlorides; Cytoplasm; Ferric Compounds; Flow Cytometry; Integrins; Mice; Mice, Transgenic; Microscopy; Models, Genetic; Platelet Adhesiveness; Platelet Aggregation; Talin; Thrombosis | 2007 |
Serglycin proteoglycan deletion induces defects in platelet aggregation and thrombus formation in mice.
Topics: Adenosine Triphosphate; Animals; beta-Thromboglobulin; Blood Platelets; Chlorides; Ferric Compounds; Fibrinogen; Hematopoietic Stem Cells; Mast Cells; Megakaryocytes; Mice; Mice, Knockout; Neutrophils; Noxae; Oligopeptides; P-Selectin; Platelet Aggregation; Platelet Factor 4; Platelet Membrane Glycoprotein IIb; Proteoglycans; Receptors, Thrombin; Secretory Vesicles; Serotonin; T-Lymphocytes, Cytotoxic; Thrombin; Thrombosis; Vesicular Transport Proteins | 2008 |
GSK3beta is a negative regulator of platelet function and thrombosis.
Topics: Animals; Blood Platelets; Carotid Artery Injuries; Chlorides; Disease Models, Animal; Enzyme Inhibitors; Ferric Compounds; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Mice; Mice, Knockout; Noxae; Phosphorylation; Platelet Aggregation; Proto-Oncogene Proteins c-akt; Thrombosis | 2008 |
Obesity promotes injury induced femoral artery thrombosis in mice.
Topics: Animals; Antithrombins; Blood Coagulation; Body Weight; Chlorides; Factor V; Femoral Artery; Ferric Compounds; Humans; Male; Mice; Models, Statistical; Obesity; Plasminogen Activator Inhibitor 1; Risk; Thrombosis | 2008 |
Inhibition of plasminogen activator inhibitor-1: its mechanism and effectiveness on coagulation and fibrosis.
Topics: Animals; Anticoagulants; Arteriovenous Shunt, Surgical; Binding Sites; Bleomycin; Blood Coagulation; Chlorides; Computer Simulation; Drug Evaluation, Preclinical; Ferric Compounds; Male; Mice; Mice, Inbred C57BL; Models, Molecular; Plasminogen Activator Inhibitor 1; Protein Conformation; Pulmonary Fibrosis; Rats; Serpin E2; Serpins; Testis; Thrombosis; User-Computer Interface | 2008 |
Cigarette smoke exposure promotes arterial thrombosis and vessel remodeling after vascular injury in apolipoprotein E-deficient mice.
Topics: Actins; Animals; Apolipoproteins E; Apoptosis; Carotid Artery Diseases; Cell Proliferation; Cells, Cultured; Chlorides; Disease Models, Animal; Dose-Response Relationship, Drug; Ferric Compounds; Humans; Male; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Smoke; Smoking; Thrombosis; Time Factors; Vascular Patency | 2008 |
Lipopolysaccharide augments venous and arterial thrombosis in the mouse.
Topics: Animals; Arteries; Carotid Artery Thrombosis; Chlorides; Disease Models, Animal; Dose-Response Relationship, Drug; Ferric Compounds; Fibrinolytic Agents; Interleukin-1beta; Lipopolysaccharides; Mice; Mice, Inbred C57BL; RNA, Messenger; Thrombosis; Time Factors; Tumor Necrosis Factor-alpha; Veins; Venae Cavae; Venous Thrombosis | 2008 |
Prediction of the therapeutic index of marketed anti-coagulants and anti-platelet agents by guinea pig models of thrombosis and hemostasis.
Topics: Animals; Anticoagulants; Arginine; Arteriovenous Shunt, Surgical; Aspirin; Bleeding Time; Chlorides; Ferric Compounds; Guinea Pigs; Hemostasis; Male; Pipecolic Acids; Platelet Aggregation Inhibitors; Sulfonamides; Thrombosis; Tirofiban; Tyrosine | 2008 |
[Calcitonin gene-related peptide and thrombolysis].
Topics: Animals; Calcitonin Gene-Related Peptide; Chlorides; Female; Ferric Compounds; Humans; Male; Middle Aged; Myocardial Infarction; Rats; Rats, Wistar; Thrombolytic Therapy; Thrombosis; Urokinase-Type Plasminogen Activator | 1993 |
L-374,087, an efficacious, orally bioavailable, pyridinone acetamide thrombin inhibitor.
Topics: Administration, Oral; Animals; Anticoagulants; Biological Availability; Chlorides; Crystallography, X-Ray; Dogs; Ferric Compounds; Kinetics; Macaca fascicularis; Models, Molecular; Molecular Structure; Pyridones; Rats; Structure-Activity Relationship; Sulfonamides; Thrombin; Thrombosis; Trypsin | 1998 |
Inhibition of arterial thrombus formation by ApoA1 Milano.
Topics: Animals; Aorta, Abdominal; Aortic Diseases; Apolipoprotein A-I; Chlorides; Cholesterol; Cholesterol, HDL; Ferric Compounds; Humans; Microscopy, Electron, Scanning; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Thrombosis; Time Factors | 1999 |
Pharmacological effects of a novel recombinant hirudin, CX-397, in vivo and in vitro: comparison with recombinant hirudin variant-1, heparin, and argatroban.
Topics: Amino Acid Sequence; Animals; Arginine; Arterial Occlusive Diseases; Arteriovenous Shunt, Surgical; Chlorides; Drug Evaluation, Preclinical; Ferric Compounds; Fibrinolytic Agents; Glass; Hemorrhage; Heparin; Hirudin Therapy; Hirudins; Molecular Sequence Data; Pipecolic Acids; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Serine Proteinase Inhibitors; Sulfonamides; Thrombin; Thrombosis; Vena Cava, Inferior; Venous Thrombosis | 1999 |
Demonstration of flow and platelet dependency in a ferric chloride-induced model of thrombosis.
Topics: Animals; Antifibrinolytic Agents; Antithrombins; Arterial Occlusive Diseases; Aspirin; Blood Platelets; Carotid Artery Diseases; Carotid Artery, Common; Chlorides; Ferric Compounds; Fibrinolytic Agents; Heparin; Hirudins; Immune Sera; Ligation; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Thrombosis; Tranexamic Acid | 1999 |
Plasminogen activator inhibitor-1 is a major determinant of arterial thrombolysis resistance.
Topics: Animals; Blood Platelets; Carotid Arteries; Carotid Stenosis; Chlorides; Ferric Compounds; Genetic Predisposition to Disease; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Plasminogen; Plasminogen Activator Inhibitor 1; Thrombolytic Therapy; Thrombosis; Tissue Plasminogen Activator | 1999 |
Z-335, a new thromboxane A(2) receptor antagonist, prevents arterial thrombosis induced by ferric chloride in rats.
Topics: Administration, Oral; Animals; Aorta, Abdominal; Chlorides; Cilostazol; Dose-Response Relationship, Drug; Ferric Compounds; Fibrinolytic Agents; Indans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Thromboxane; Tetrazoles; Thrombosis; Time Factors | 2000 |
Plasminogen activator inhibitor-1 and its cofactor vitronectin stabilize arterial thrombi after vascular injury in mice.
Topics: Actins; Animals; Blood Circulation; Carotid Arteries; Carotid Artery Injuries; Chlorides; Female; Ferric Compounds; Gene Expression; Genotype; Immunohistochemistry; In Situ Hybridization; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Muscle, Smooth, Vascular; Plasminogen Activator Inhibitor 1; RNA, Messenger; Thrombosis; Time Factors; Vimentin; Vitronectin | 2001 |
Plasminogen activator inhibitor type 1 enhances neointima formation after oxidative vascular injury in atherosclerosis-prone mice.
Topics: Animals; Apolipoproteins E; Arteriosclerosis; Carotid Artery Injuries; Carotid Artery, Common; Cell Division; Chlorides; Cholesterol, Dietary; Female; Ferric Compounds; Genotype; Hyperplasia; Lipid Metabolism; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Plasminogen Activator Inhibitor 1; Thrombosis; Tunica Intima | 2001 |
Variable protection of beta 3-integrin--deficient mice from thrombosis initiated by different mechanisms.
Topics: Animals; Antibodies, Monoclonal; Antigens, CD; Blood Platelets; Carotid Artery Thrombosis; Chlorides; Disease Models, Animal; Female; Ferric Compounds; Fibrin; Immunohistochemistry; Integrin beta3; Male; Mice; Mice, Knockout; Microcirculation; Microscopy, Electron; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoproteins; Receptors, Vitronectin; Thrombosis | 2001 |
Characterization of a mouse model for thrombomodulin deficiency.
Topics: Animals; Blood Coagulation; Carotid Artery Thrombosis; Chlorides; Cytokines; Ferric Compounds; Fibrin; Genetic Predisposition to Disease; Ligation; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Sepsis; Survival Analysis; Thrombomodulin; Thrombosis | 2001 |
Magnesium inhibits arterial thrombi after vascular injury in rat: in vivo impairment of coagulation.
Topics: Animals; Blood Coagulation Tests; Carotid Arteries; Chlorides; Disease Models, Animal; Dose-Response Relationship, Drug; Ferric Compounds; Hemostasis; Magnesium Sulfate; Male; Platelet Aggregation; Rats; Rats, Sprague-Dawley; Thrombosis; Time Factors | 2001 |
CD40L stabilizes arterial thrombi by a beta3 integrin--dependent mechanism.
Topics: Animals; Arterioles; Blood Platelets; CD40 Ligand; Cell Adhesion; Chlorides; Ferric Compounds; Hemodynamics; Humans; In Vitro Techniques; Mesentery; Mice; Mice, Inbred C57BL; Mice, Knockout; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombosis | 2002 |