Page last updated: 2024-10-27

fentanyl and Visceral Pain

fentanyl has been researched along with Visceral Pain in 5 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Visceral Pain: Pain originating from internal organs (VISCERA) associated with autonomic phenomena (PALLOR; SWEATING; NAUSEA; and VOMITING). It often becomes a REFERRED PAIN.

Research Excerpts

ExcerptRelevanceReference
" We studied the analgesic efficacy and side-effect profile of a pH-sensitive fentanyl analog, (±)- N -(3-fluoro-1-phenethylpiperidine-4-yl)- N -phenyl propionamide (NFEPP), during the evolution of colitis induced in mice with dextran sulphate sodium."4.31Evolving acidic microenvironments during colitis provide selective analgesic targets for a pH-sensitive opioid. ( Alizadeh, E; Bunnett, NW; Degro, CE; Guzman-Rodriguez, M; Hurlbut, D; Jiménez-Vargas, NN; Lomax, AE; Reed, DE; Stein, C; Tsang, Q; Vanner, SJ; Yu, Y, 2023)
"Antinociceptive actions of NFEPP and fentanyl were compared in control mice and mice with dextran sodium sulfate colitis by measuring visceromotor responses to colorectal distension."4.12Agonist that activates the µ-opioid receptor in acidified microenvironments inhibits colitis pain without side effects. ( Bok, DD; Bunnett, NW; Degro, C; Guzman-Rodriguez, M; Jaramillo-Polanco, JO; Jensen, DD; Jiménez-Vargas, NN; Latorre, R; Lomax, AE; Lopez, C; Margolis, KG; Reed, DE; Schmidt, BL; Snow, Z; Stein, C; Tsang, Q; Vanner, SJ; Wisdom, M; Yu, Y, 2022)
" Here, we attempted to characterize a synergistic interaction between fentanyl, tramadol, and paracetamol on the inhibition of nociception in a model of visceral pain in mice."3.78Synergistic interaction between fentanyl and a tramadol: paracetamol combination on the inhibition of nociception in mice. ( Ciruela, F; Fernández-Dueñas, V; Poveda, R; Sánchez, S, 2012)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (60.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Degro, CE1
Jiménez-Vargas, NN2
Tsang, Q2
Yu, Y2
Guzman-Rodriguez, M2
Alizadeh, E1
Hurlbut, D1
Reed, DE2
Lomax, AE2
Stein, C2
Bunnett, NW2
Vanner, SJ2
Jensen, DD1
Bok, DD1
Wisdom, M1
Latorre, R1
Lopez, C1
Jaramillo-Polanco, JO1
Degro, C1
Snow, Z1
Schmidt, BL1
Margolis, KG1
Ly, HG1
Dupont, P1
Geeraerts, B1
Bormans, G1
Van Laere, K1
Tack, J1
Van Oudenhove, L1
Cha, SM1
Kang, H1
Baek, CW1
Jung, YH1
Koo, GH1
Kim, BG1
Choi, YS1
Cha, SJ1
Cha, YJ1
Fernández-Dueñas, V1
Poveda, R1
Sánchez, S1
Ciruela, F1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized Controlled Study of the Effect of Intraperitoneal Ropivacaine on Visceral Pain After Laparoscopic Gastrectomy[NCT06145945]72 participants (Anticipated)Interventional2023-11-25Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for fentanyl and Visceral Pain

ArticleYear
Lack of endogenous opioid release during sustained visceral pain: a [11C]carfentanil PET study.
    Pain, 2013, Volume: 154, Issue:10

    Topics: Adolescent; Adult; Carbon Radioisotopes; Female; Fentanyl; Humans; Male; Opioid Peptides; Positron-E

2013
Peritrocal and intraperitoneal ropivacaine for laparoscopic cholecystectomy: a prospective, randomized, double-blind controlled trial.
    The Journal of surgical research, 2012, Jun-15, Volume: 175, Issue:2

    Topics: Administration, Topical; Adult; Aged; Amides; Anesthetics, Intravenous; Anesthetics, Local; Cholecys

2012

Other Studies

3 other studies available for fentanyl and Visceral Pain

ArticleYear
Evolving acidic microenvironments during colitis provide selective analgesic targets for a pH-sensitive opioid.
    Pain, 2023, Nov-01, Volume: 164, Issue:11

    Topics: Analgesics; Analgesics, Opioid; Animals; Colitis; Colon; Fentanyl; Humans; Hydrogen-Ion Concentratio

2023
Agonist that activates the µ-opioid receptor in acidified microenvironments inhibits colitis pain without side effects.
    Gut, 2022, Volume: 71, Issue:4

    Topics: Animals; Colitis; Colon; Colorectal Neoplasms; Constipation; Fentanyl; Humans; Inflammatory Bowel Di

2022
Synergistic interaction between fentanyl and a tramadol: paracetamol combination on the inhibition of nociception in mice.
    Journal of pharmacological sciences, 2012, Volume: 118, Issue:2

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Disease Models, Animal; Drug S

2012