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fentanyl and Ventricular Fibrillation

fentanyl has been researched along with Ventricular Fibrillation in 20 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Ventricular Fibrillation: A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST.

Research Excerpts

ExcerptRelevanceReference
"The present study was performed to compare haemodynamic variables at baseline and the incidence of ventricular fibrillation during the early phase of ischaemia in swine during pentobarbital or medetomidine-ketamine-fentanyl anaesthesia."7.72Pentobarbital versus medetomidine-ketamine-fentanyl anaesthesia: effects on haemodynamics and the incidence of ischaemia-induced ventricular fibrillation in swine. ( Grund, F; Ilebekk, A; Kirkebøen, KA; Sjaastad, I; Tjomsland, O, 2004)
"Neither halothane nor sevoflurane protected the heart against the effects of acute and severe regional myocardial ischemia."7.70Anesthetic modulation of myocardial ischemia and reperfusion injury in pigs: comparison between halothane and sevoflurane. ( Coetzee, A; Coetzee, J; Conradie, S, 1999)
"The anesthetic management of the first stage palliative surgical repair of hypoplastic left heart syndrome with a high-dose fentanyl (50 micrograms/kg)-pancuronium (0."7.67Anesthesia for hypoplastic left heart syndrome: use of high-dose fentanyl in 30 neonates. ( Hansen, DD; Hickey, PR, 1986)
"Pericardial lidocaine (1) decreased heart rate without affecting stroke volume, (2) preserved the tachycardiac response to isoproterenol but completely blocked the response to atropine, and (3) increased the voltage thresholds for arrhythmias and ventricular fibrillation induced by an electrical fibrillator."3.74Effects of pericardial lidocaine on hemodynamic parameters and responses in dogs anesthetized with midazolam and fentanyl. ( Akamatsu, S; Dohi, S; Suzuki, A; Takada, M, 2007)
"The present study was performed to compare haemodynamic variables at baseline and the incidence of ventricular fibrillation during the early phase of ischaemia in swine during pentobarbital or medetomidine-ketamine-fentanyl anaesthesia."3.72Pentobarbital versus medetomidine-ketamine-fentanyl anaesthesia: effects on haemodynamics and the incidence of ischaemia-induced ventricular fibrillation in swine. ( Grund, F; Ilebekk, A; Kirkebøen, KA; Sjaastad, I; Tjomsland, O, 2004)
"Neither halothane nor sevoflurane protected the heart against the effects of acute and severe regional myocardial ischemia."3.70Anesthetic modulation of myocardial ischemia and reperfusion injury in pigs: comparison between halothane and sevoflurane. ( Coetzee, A; Coetzee, J; Conradie, S, 1999)
"Fentanyl, a mu selective opioid agonist in wide clinical use, raises the ventricular fibrillation threshold in the normal canine myocardium."3.67Comparative effects of the opioids fentanyl and buprenorphine on ventricular vulnerability during acute coronary artery occlusion. ( Carr, DB; Saini, V; Verrier, RL, 1989)
"To determine the effect of strong analgesics on electrical instability (vulnerability to ventricular fibrillation), we examined the action of fentanyl (60 micrograms/kg), sufentanil (10 micrograms/kg) and carfentanil (3 micrograms/kg) on the ventricular fibrillation threshold (VFT) in a dog model of coronary artery occlusion."3.67The antifibrillatory effect of fentanyl, sufentanil and carfentanil in the acute phase of local myocardial ischaemia in the dog. ( Fejfar, Z; Hess, L; Vrana, M; Vranova, Z, 1989)
" Following an uneventful induction of anaesthesia with halothane, nitrous oxide and O2, succinylcholine resulted in bilateral masseter muscle spasm and then, in rapid sequence, ventricular tachycardia and cardiac arrest."3.67Duchenne muscular dystrophy and malignant hyperthermia--two case reports. ( Stanley, TH; Wang, JM, 1986)
"The anesthetic management of the first stage palliative surgical repair of hypoplastic left heart syndrome with a high-dose fentanyl (50 micrograms/kg)-pancuronium (0."3.67Anesthesia for hypoplastic left heart syndrome: use of high-dose fentanyl in 30 neonates. ( Hansen, DD; Hickey, PR, 1986)
"Complications, including fatal cardiac arrhythmias, have been greatly reduced by anesthetic protocols and surgical procedures developed through experience."1.27Anatomic and anesthetic considerations in experimental cardiopulmonary surgery in swine. ( Baumgartner, WA; Borkon, AM; Galloway, E; Gardner, TJ; Gott, VL; Hall, TS; Horneffer, PJ; Reitz, BA; Stuart, RS; Swindle, MM, 1986)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199011 (55.00)18.7374
1990's4 (20.00)18.2507
2000's4 (20.00)29.6817
2010's1 (5.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sharma, RK1
Mandal, B1
Kaur, G1
Batra, YK1
Mahajan, S1
Yamagishi, A1
Hamada, I1
Takahata, O1
Nagashima, M1
Fujimoto, K1
Iwasaki, H1
Grund, F1
Tjomsland, O1
Sjaastad, I1
Ilebekk, A1
Kirkebøen, KA1
Takada, M1
Dohi, S1
Akamatsu, S1
Suzuki, A1
Ohnishi, Y1
Kikumoto, K1
Hayami, H1
Kuro, M1
Conradie, S1
Coetzee, A1
Coetzee, J1
Vrána, M3
Fejfar, Z3
Hess, L3
Blazek, Z1
Wang, M1
Dorian, P1
Saini, V2
Carr, DB2
Verrier, RL2
Vranova, Z2
Hagestad, EL1
Lown, B1
Swindle, MM1
Horneffer, PJ1
Gardner, TJ1
Gott, VL1
Hall, TS1
Stuart, RS1
Baumgartner, WA1
Borkon, AM1
Galloway, E1
Reitz, BA1
Wang, JM1
Stanley, TH1
Hansen, DD1
Hickey, PR1
Szabuniewicz, M1
McCrady, JD1
Tevelenok, IuA1
Iwatsuki, K1
Sasamori, N1
Sato, K1
Aoba, Y1
Yasuka, I1

Reviews

1 review available for fentanyl and Ventricular Fibrillation

ArticleYear
Antifibrillatory action of the narcotic agonist fentanyl.
    American heart journal, 1988, Volume: 115, Issue:3

    Topics: Animals; Atropine; Atropine Derivatives; Blood Pressure; Cardiac Pacing, Artificial; Dogs; Electric

1988

Other Studies

19 other studies available for fentanyl and Ventricular Fibrillation

ArticleYear
Retrospective diagnosis of cocaine addiction: role of preoperative electrocardiogram.
    Anaesthesia and intensive care, 2008, Volume: 36, Issue:5

    Topics: Androstanols; Anesthetics, Intravenous; Cocaine-Related Disorders; Contracture; Electrocardiography;

2008
Manifestation of Long QT syndrome with normal QTc interval under anesthesia: a case report.
    Paediatric anaesthesia, 2011, Volume: 21, Issue:12

    Topics: Adrenergic alpha-Agonists; Anesthesia; Anti-Arrhythmia Agents; Atracurium; Atropine; Cardiopulmonary

2011
[Suppression of frequent ventricular fibrillation attacks after induction of anesthesia with fentanyl, sevoflurane and propofol: a case report].
    Masui. The Japanese journal of anesthesiology, 2003, Volume: 52, Issue:7

    Topics: Anesthetics, General; Anesthetics, Intravenous; Defibrillators, Implantable; Fentanyl; Humans; Male;

2003
Pentobarbital versus medetomidine-ketamine-fentanyl anaesthesia: effects on haemodynamics and the incidence of ischaemia-induced ventricular fibrillation in swine.
    Laboratory animals, 2004, Volume: 38, Issue:1

    Topics: Anesthesia; Anesthetics; Animals; Constriction; Coronary Vessels; Female; Fentanyl; Hemodynamics; Is

2004
Effects of pericardial lidocaine on hemodynamic parameters and responses in dogs anesthetized with midazolam and fentanyl.
    Journal of cardiothoracic and vascular anesthesia, 2007, Volume: 21, Issue:3

    Topics: Anesthesia; Animals; Coronary Artery Bypass, Off-Pump; Dogs; Fentanyl; Heart Rate; Lidocaine; Midazo

2007
[Anesthetic management for AICD (automatic implantable cardioverter defibrillator) implant surgery].
    Masui. The Japanese journal of anesthesiology, 1996, Volume: 45, Issue:2

    Topics: Anesthesia, General; Anesthesia, Inhalation; Anesthetics, Intravenous; Defibrillators, Implantable;

1996
Anesthetic modulation of myocardial ischemia and reperfusion injury in pigs: comparison between halothane and sevoflurane.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1999, Volume: 46, Issue:1

    Topics: Adjuvants, Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Fentanyl; Halotha

1999
Katie Dougal. A legacy for improvement.
    SAAD digest, 1998, Volume: 15, Issue:2

    Topics: Anesthesia, Dental; Anesthesia, General; Anesthetics, Intravenous; Cause of Death; Child; England; F

1998
Analgosedation-enhanced baroreflex sensitivity in acute local myocardial ischaemia.
    Cor et vasa, 1991, Volume: 33, Issue:5

    Topics: Animals; Blood Pressure; Coronary Disease; Dogs; Electrocardiography; Fentanyl; Midazolam; Pressorec

1991
DL and D sotalol decrease defibrillation energy requirements.
    Pacing and clinical electrophysiology : PACE, 1989, Volume: 12, Issue:9

    Topics: Animals; Dogs; Electric Countershock; Electrocardiography; Enflurane; Female; Fentanyl; Male; Pentob

1989
Comparative effects of the opioids fentanyl and buprenorphine on ventricular vulnerability during acute coronary artery occlusion.
    Cardiovascular research, 1989, Volume: 23, Issue:12

    Topics: Animals; Buprenorphine; Coronary Disease; Dogs; Fentanyl; Heart Conduction System; Receptors, Opioid

1989
The antifibrillatory effect of fentanyl, sufentanil and carfentanil in the acute phase of local myocardial ischaemia in the dog.
    Acta cardiologica, 1989, Volume: 44, Issue:4

    Topics: Adrenergic beta-Antagonists; Analgesics, Opioid; Animals; Celiprolol; Coronary Disease; Dogs; Fentan

1989
The electrostabilizing effect of a combination of midazolam and fentanyl: an experimental study in the dog.
    Cor et vasa, 1989, Volume: 31, Issue:5

    Topics: Animals; Blood Pressure; Dogs; Drug Combinations; Electrocardiography; Fentanyl; Heart Conduction Sy

1989
Anatomic and anesthetic considerations in experimental cardiopulmonary surgery in swine.
    Laboratory animal science, 1986, Volume: 36, Issue:4

    Topics: Acepromazine; Anesthesia; Animals; Arrhythmias, Cardiac; Bradycardia; Cardiopulmonary Bypass; Cardio

1986
Duchenne muscular dystrophy and malignant hyperthermia--two case reports.
    Canadian Anaesthetists' Society journal, 1986, Volume: 33, Issue:4

    Topics: Anesthesia, Inhalation; Child, Preschool; Fentanyl; Halothane; Humans; Hyperkalemia; Infant; Male; M

1986
Anesthesia for hypoplastic left heart syndrome: use of high-dose fentanyl in 30 neonates.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:2

    Topics: Anesthesia; Cardiopulmonary Bypass; Fentanyl; Heart Defects, Congenital; Humans; Infant, Newborn; Ox

1986
Some aspects of the anatomy and physiology of the armadillo.
    Laboratory animal care, 1969, Volume: 19, Issue:6

    Topics: Animals; Blood Pressure; Carotid Arteries; Electric Stimulation; Electrocardiography; Epinephrine; F

1969
[Use of drugs for neuroleptoanalgesia in the acute period of a myocardial infarct].
    Kardiologiia, 1971, Volume: 11, Issue:12

    Topics: Acid-Base Equilibrium; Acute Disease; Aged; Benperidol; Blood Volume; Carbon Dioxide; Female; Fentan

1971
[Clinical evaluation of neuroleptoanalgesia].
    Masui. The Japanese journal of anesthesiology, 1968, Volume: 17, Issue:6

    Topics: Acid-Base Equilibrium; Adolescent; Adult; Aged; Benperidol; Blood Gas Analysis; Blood Pressure; Chil

1968