Page last updated: 2024-10-27

fentanyl and Surgical Incision

fentanyl has been researched along with Surgical Incision in 5 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Research Excerpts

ExcerptRelevanceReference
"We tested the following hypothesis: The addition of intranasal fentanyl to the standard practice of local infiltration with lidocaine would provide better pain control than lidocaine alone for adult ED patients undergoing I&D."9.51A Randomized, Placebo-Controlled Study of Intranasal Fentanyl as an Analgesic Adjunct For Incision and Drainage of Abscess. ( Baer, J; Feliciano, C; Friedman, BW; Gupta, C; Latev, A; Sharpe, S, 2022)
"5 mg/kg lignocaine over 15 min, starting approximately 15 min before the surgical incision and fentanyl 0."5.69A comparison of two techniques of postoperative analgesia: lignocaine-fentanyl intravenous infusion and ropivacaine-fentanyl epidural infusion in patients undergoing cytoreductive cancer surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC)- ( Bharati, SJ; Bhatnagar, S; Deo, S; Garg, R; Gupta, N; Kumar, V; Mahendru, K; Mishra, S; Ray, M, 2023)
"We tested the following hypothesis: The addition of intranasal fentanyl to the standard practice of local infiltration with lidocaine would provide better pain control than lidocaine alone for adult ED patients undergoing I&D."5.51A Randomized, Placebo-Controlled Study of Intranasal Fentanyl as an Analgesic Adjunct For Incision and Drainage of Abscess. ( Baer, J; Feliciano, C; Friedman, BW; Gupta, C; Latev, A; Sharpe, S, 2022)
"Fentanyl 1 µg/kg bolus was administered when ANI decreased to <50."2.87Analgesia Nociception Index-guided intraoperative fentanyl consumption and postoperative analgesia in patients receiving scalp block versus incision-site infiltration for craniotomy. ( Chakrabarti, D; Reddy, KM; Sriganesh, K; Theerth, KA; Umamaheswara Rao, GS, 2018)
"The fentanyl or surgical incision upregulated the expression of IL-1β, IL-6, and TNF-α in the spinal cord and bilateral DRG for more than 7 days and increase of ionized calcium-binding adapter molecule 1 in the spinal cord."1.48Increased Hyperalgesia and Proinflammatory Cytokines in the Spinal Cord and Dorsal Root Ganglion After Surgery and/or Fentanyl Administration in Rats. ( Chang, L; Luo, Q; Shu, H; Tao, Y; Ye, F, 2018)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (60.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Latev, A1
Baer, J1
Sharpe, S1
Gupta, C1
Feliciano, C1
Friedman, BW1
Mahendru, K1
Garg, R1
Bharati, SJ1
Kumar, V1
Gupta, N1
Mishra, S1
Bhatnagar, S1
Ray, M1
Deo, S1
Chang, L2
Ye, F2
Luo, Q2
Tao, Y1
Shu, H2
Wang, Z1
Wang, Y1
Xia, Z1
Theerth, KA1
Sriganesh, K1
Reddy, KM1
Chakrabarti, D1
Umamaheswara Rao, GS1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Ability of the Analgesia Nociception Index Monitor to Distinguish Between Excessive Analgesia and Inadvertent Parasympathetic Nerve Stimulation During Surgery of Large Cerebellopontine Angle Tumours[NCT03978819]100 participants (Actual)Observational2015-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for fentanyl and Surgical Incision

ArticleYear
A Randomized, Placebo-Controlled Study of Intranasal Fentanyl as an Analgesic Adjunct For Incision and Drainage of Abscess.
    The Journal of emergency medicine, 2022, Volume: 62, Issue:3

    Topics: Abscess; Administration, Intranasal; Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Dra

2022
A comparison of two techniques of postoperative analgesia: lignocaine-fentanyl intravenous infusion and ropivacaine-fentanyl epidural infusion in patients undergoing cytoreductive cancer surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC)-
    Langenbeck's archives of surgery, 2023, Aug-24, Volume: 408, Issue:1

    Topics: Analgesia, Epidural; Cytoreduction Surgical Procedures; Fentanyl; Humans; Hyperthermic Intraperitone

2023
Analgesia Nociception Index-guided intraoperative fentanyl consumption and postoperative analgesia in patients receiving scalp block versus incision-site infiltration for craniotomy.
    Minerva anestesiologica, 2018, Volume: 84, Issue:12

    Topics: Adult; Analgesics, Opioid; Craniotomy; Double-Blind Method; Female; Fentanyl; Humans; Intraoperative

2018

Other Studies

2 other studies available for fentanyl and Surgical Incision

ArticleYear
Increased Hyperalgesia and Proinflammatory Cytokines in the Spinal Cord and Dorsal Root Ganglion After Surgery and/or Fentanyl Administration in Rats.
    Anesthesia and analgesia, 2018, Volume: 126, Issue:1

    Topics: Analgesics, Opioid; Animals; Cytokines; Fentanyl; Ganglia, Spinal; Hyperalgesia; Inflammation Mediat

2018
Effects of three forms of local anesthesia on perioperative fentanyl-induced hyperalgesia.
    Bioscience trends, 2018, May-13, Volume: 12, Issue:2

    Topics: Anesthesia, Local; Animals; Disease Models, Animal; Fentanyl; Ganglia, Spinal; Humans; Hyperalgesia;

2018