fentanyl has been researched along with Sleep Apnea Syndromes in 5 studies
Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.
Sleep Apnea Syndromes: Disorders characterized by multiple cessations of respirations during sleep that induce partial arousals and interfere with the maintenance of sleep. Sleep apnea syndromes are divided into central (see SLEEP APNEA, CENTRAL), obstructive (see SLEEP APNEA, OBSTRUCTIVE), and mixed central-obstructive types.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The treatment of postoperative pain after uvulopalatopharyngoplasty (UPPP) and tonsillectomy presents a challenge." | 2.69 | Ketoprofen and fentanyl for pain after uvulopalatopharyngoplasty and tonsillectomy. ( Aho, M; Kokki, H; Nikanne, E; Virtaniemi, J, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mikhaeil, JS | 1 |
| Pepper, CG | 1 |
| Hayward, GC | 1 |
| Ajala, AM | 1 |
| Goodwin, JA | 1 |
| Goodwin, SR | 1 |
| Josephson, GD | 1 |
| Ostermeier, AM | 1 |
| Roizen, MF | 1 |
| Hautkappe, M | 1 |
| Klock, PA | 1 |
| Klafta, JM | 1 |
| Virtaniemi, J | 1 |
| Kokki, H | 1 |
| Nikanne, E | 1 |
| Aho, M | 1 |
| Esclamado, RM | 1 |
| Glenn, MG | 1 |
| McCulloch, TM | 1 |
| Cummings, CW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Postoperative Management of Obstructive Sleep Apnea With CPAP vs. an Autoadjusting CPAP Device: a Randomized Controlled Single Center Trial[NCT00588848] | 11 participants (Actual) | Interventional | 2008-01-31 | Terminated (stopped due to Difficulty with enrollment) | |||
| The Effect of Acute Intravenous Morphine Administration on Sleep Disordered Breathing (SDB) in Patients With Moderate Obstructive Sleep Apnoea (OSA): A Paired Design Trial[NCT03127800] | Phase 3 | 6 participants (Actual) | Interventional | 2016-05-20 | Terminated (stopped due to Difficulties with recruitment) | ||
| Evaluation of Treatment Effect of Cervical Collar in Moderate Obstructive Sleep Apnea[NCT03754270] | 100 participants (Actual) | Interventional | 2019-06-16 | Completed | |||
| The Association of CPAP Compliance and Nocturnal Hypoxemia in the Perioperative Period[NCT02796846] | 158 participants (Actual) | Observational | 2015-06-30 | Completed | |||
| Evaluation of Screening Tools for OSA in Hospitalized Medical Patients: A Validation Study[NCT01340781] | 110 participants (Actual) | Observational | 2012-02-29 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Events are defined as apneas and hypopneas. AHI values are typically categorized as 5-14.9 events/hr = mild; 15-29.9 events/hr = moderate; and >= 30 events/hr = severe (NCT00588848)
Timeframe: On postoperative night number 1 from 2200 to 0600. Study participation will end within 72 hours of admission.
| Intervention | events per hour (Mean) |
|---|---|
| AUTOCPAP | 2.1 |
| CPAP | 1.2 |
Predefined cardiopulmonary complications: Myocardial Infarction, Arrhythmia, new onset Heart Failure, Stroke (NCT00588848)
Timeframe: 72 hours
| Intervention | Participants (Count of Participants) |
|---|---|
| Autoadjusting CPAP (VPAP Auto) | 0 |
| CPAP Arm (Usual Care) | 0 |
(NCT00588848)
Timeframe: On postoperative night number 1 from 2200 to 0600. Study participation will end within 72 hours of admission.
| Intervention | Percentage of time < 90% saturation (Mean) |
|---|---|
| AUTOCPAP | 10.5 |
| CPAP | 7.1 |
1 review available for fentanyl and Sleep Apnea Syndromes
| Article | Year |
|---|---|
Three sudden postoperative respiratory arrests associated with epidural opioids in patients with sleep apnea.
Topics: Adult; Aged; Analgesia, Epidural; Analgesics, Opioid; Apnea; Blood Pressure; Bupivacaine; Female; Fe | 1997 |
Three sudden postoperative respiratory arrests associated with epidural opioids in patients with sleep apnea.
Topics: Adult; Aged; Analgesia, Epidural; Analgesics, Opioid; Apnea; Blood Pressure; Bupivacaine; Female; Fe | 1997 |
Three sudden postoperative respiratory arrests associated with epidural opioids in patients with sleep apnea.
Topics: Adult; Aged; Analgesia, Epidural; Analgesics, Opioid; Apnea; Blood Pressure; Bupivacaine; Female; Fe | 1997 |
Three sudden postoperative respiratory arrests associated with epidural opioids in patients with sleep apnea.
Topics: Adult; Aged; Analgesia, Epidural; Analgesics, Opioid; Apnea; Blood Pressure; Bupivacaine; Female; Fe | 1997 |
1 trial available for fentanyl and Sleep Apnea Syndromes
| Article | Year |
|---|---|
Ketoprofen and fentanyl for pain after uvulopalatopharyngoplasty and tonsillectomy.
Topics: Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Female; Fentanyl; Humans; Infusi | 1999 |
3 other studies available for fentanyl and Sleep Apnea Syndromes
| Article | Year |
|---|---|
Mechanisms of opioid-induced respiratory depression in sleep apnoea: new insights for anaesthesiology.
Topics: Analgesics, Opioid; Anesthesiology; Fentanyl; Humans; Hypercapnia; Hypoxia; Respiratory Hypersensiti | 2020 |
Undiagnosed Graves' Disease contributing to sleep disordered breathing in a child undergoing adenotonsillectomy.
Topics: Acetaminophen; Adenoidectomy; Adenoids; Analgesics, Non-Narcotic; Analgesics, Opioid; Antihypertensi | 2008 |
Perioperative complications and risk factors in the surgical treatment of obstructive sleep apnea syndrome.
Topics: Adjuvants, Anesthesia; Adult; Airway Obstruction; Arrhythmias, Cardiac; Chi-Square Distribution; Fem | 1989 |
Perioperative complications and risk factors in the surgical treatment of obstructive sleep apnea syndrome.
Topics: Adjuvants, Anesthesia; Adult; Airway Obstruction; Arrhythmias, Cardiac; Chi-Square Distribution; Fem | 1989 |
Perioperative complications and risk factors in the surgical treatment of obstructive sleep apnea syndrome.
Topics: Adjuvants, Anesthesia; Adult; Airway Obstruction; Arrhythmias, Cardiac; Chi-Square Distribution; Fem | 1989 |
Perioperative complications and risk factors in the surgical treatment of obstructive sleep apnea syndrome.
Topics: Adjuvants, Anesthesia; Adult; Airway Obstruction; Arrhythmias, Cardiac; Chi-Square Distribution; Fem | 1989 |
Perioperative complications and risk factors in the surgical treatment of obstructive sleep apnea syndrome.
Topics: Adjuvants, Anesthesia; Adult; Airway Obstruction; Arrhythmias, Cardiac; Chi-Square Distribution; Fem | 1989 |
Perioperative complications and risk factors in the surgical treatment of obstructive sleep apnea syndrome.
Topics: Adjuvants, Anesthesia; Adult; Airway Obstruction; Arrhythmias, Cardiac; Chi-Square Distribution; Fem | 1989 |
Perioperative complications and risk factors in the surgical treatment of obstructive sleep apnea syndrome.
Topics: Adjuvants, Anesthesia; Adult; Airway Obstruction; Arrhythmias, Cardiac; Chi-Square Distribution; Fem | 1989 |
Perioperative complications and risk factors in the surgical treatment of obstructive sleep apnea syndrome.
Topics: Adjuvants, Anesthesia; Adult; Airway Obstruction; Arrhythmias, Cardiac; Chi-Square Distribution; Fem | 1989 |
Perioperative complications and risk factors in the surgical treatment of obstructive sleep apnea syndrome.
Topics: Adjuvants, Anesthesia; Adult; Airway Obstruction; Arrhythmias, Cardiac; Chi-Square Distribution; Fem | 1989 |
Perioperative complications and risk factors in the surgical treatment of obstructive sleep apnea syndrome.
Topics: Adjuvants, Anesthesia; Adult; Airway Obstruction; Arrhythmias, Cardiac; Chi-Square Distribution; Fem | 1989 |
Perioperative complications and risk factors in the surgical treatment of obstructive sleep apnea syndrome.
Topics: Adjuvants, Anesthesia; Adult; Airway Obstruction; Arrhythmias, Cardiac; Chi-Square Distribution; Fem | 1989 |
Perioperative complications and risk factors in the surgical treatment of obstructive sleep apnea syndrome.
Topics: Adjuvants, Anesthesia; Adult; Airway Obstruction; Arrhythmias, Cardiac; Chi-Square Distribution; Fem | 1989 |
Perioperative complications and risk factors in the surgical treatment of obstructive sleep apnea syndrome.
Topics: Adjuvants, Anesthesia; Adult; Airway Obstruction; Arrhythmias, Cardiac; Chi-Square Distribution; Fem | 1989 |
Perioperative complications and risk factors in the surgical treatment of obstructive sleep apnea syndrome.
Topics: Adjuvants, Anesthesia; Adult; Airway Obstruction; Arrhythmias, Cardiac; Chi-Square Distribution; Fem | 1989 |
Perioperative complications and risk factors in the surgical treatment of obstructive sleep apnea syndrome.
Topics: Adjuvants, Anesthesia; Adult; Airway Obstruction; Arrhythmias, Cardiac; Chi-Square Distribution; Fem | 1989 |
Perioperative complications and risk factors in the surgical treatment of obstructive sleep apnea syndrome.
Topics: Adjuvants, Anesthesia; Adult; Airway Obstruction; Arrhythmias, Cardiac; Chi-Square Distribution; Fem | 1989 |