fentanyl and Sleep Apnea, Obstructive studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Sleep Apnea, Obstructive: A disorder characterized by recurrent apneas during sleep despite persistent respiratory efforts. It is due to upper airway obstruction. The respiratory pauses may induce HYPERCAPNIA or HYPOXIA. Cardiac arrhythmias and elevation of systemic and pulmonary arterial pressures may occur. Frequent partial arousals occur throughout sleep, resulting in relative SLEEP DEPRIVATION and daytime tiredness. Associated conditions include OBESITY; ACROMEGALY; MYXEDEMA; micrognathia; MYOTONIC DYSTROPHY; adenotonsilar dystrophy; and NEUROMUSCULAR DISEASES. (From Adams et al., Principles of Neurology, 6th ed, p395)

Research Excerpts

Excerpt	Relevance	Reference
"For instance, pulmonary edema (PE) has been reported to arise with the mechanism of over-sympathetic discharge caused by release of cat-echolamine or central neurogenetic responses to narcotic reversal."	5.36	Negative pressure pulmonary edema following naloxone administration in a patient with fentanyl-induced respiratory depression. ( Cherng, CH; Ho, MT; Horng, HC; Huang, CH; Yeh, CC, 2010)
"To assess effects of anesthesia and opioids, we studied 13 children with obstructive sleep apnea (OSA, age 4."	5.10	Effects of OSA, inhalational anesthesia, and fentanyl on the airway and ventilation of children. ( Hinder, M; McBrien, F; Stewart, P; Waters, KA; Wharton, S, 2002)
"This was a retrospective anesthesia chart review of 15 consecutive patients undergoing midazolam/fentanyl intravenous sedation for office-based LAUP treatment for snoring and/or mild obstructive sleep apnea."	3.73	Hemodynamics and oxygen saturation during intravenous sedation for office-based laser-assisted uvuloplasty. ( Cillo, JE; Finn, R, 2005)
"A 57-year-old male with a documented history of obstructive sleep apnea with loud snoring received deep intravenous sedation with midazolam, fentanyl, ketamine, and propofol infusion and a left interscalene brachial plexus nerve block for a left biceps tendon repair."	3.73	Uvular edema secondary to snoring under deep sedation. ( Gerhardt, MA; Miller, RJ, 2006)
"One hundred twenty-two patients with obstructive sleep apnea syndrome undergoing T&A, ages 2 to 10 years, completed this prospective, randomized, U."	2.75	Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. ( Davidson, M; Lin, A; Patel, A; Quraishi, H; Sant, M; Schoenberg, C; Sun, X; Tran, MC, 2010)
"Children with severe obstructive sleep apnea syndrome (OSAS) are more sensitive to opioids."	1.56	The performance of a postinduction fentanyl test in identifying severe obstructive sleep apnea syndrome. ( Li, Y; Wang, X; Wu, R; Zhang, F; Zhou, Z; Zhuang, P, 2020)
" Sedative and analgesic dosing was not clinically significantly higher in obese patients than in non-obese patients."	1.43	Sedation for Bronchoscopy and Complications in Obese Patients. ( Bellinger, CR; Chatterjee, AB; Haponik, E; Khan, I, 2016)
"For instance, pulmonary edema (PE) has been reported to arise with the mechanism of over-sympathetic discharge caused by release of cat-echolamine or central neurogenetic responses to narcotic reversal."	1.36	Negative pressure pulmonary edema following naloxone administration in a patient with fentanyl-induced respiratory depression. ( Cherng, CH; Ho, MT; Horng, HC; Huang, CH; Yeh, CC, 2010)

Research

Studies (15)

Authors

Clinical Trials (9)

Trial Overview

Trial Outcomes

Number of Participants Who Were Light Consumers of Morphine as Identified by the Fentanyl Test

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	5 (33.33)	29.6817
2010's	7 (46.67)	24.3611
2020's	3 (20.00)	2.80

Authors	Studies
Wu, R	1
Wang, X	2
Zhuang, P	1
Zhou, Z	1
Li, Y	1
Zhang, F	1
Roberts, C	1
Al Sayegh, R	1
Ellison, PR	1
Sedeek, K	1
Carr, MM	1
Albrecht, E	1
Bayon, V	1
Hirotsu, C	1
Heinzer, R	1
Li, YH	1
Zhou, ZJ	1
Zhuang, PJ	1
Orlov, D	1
Ankichetty, S	1
Chung, F	1
Brull, R	1
Kapoor, M	1
Herrick, D	1
Khan, I	1
Chatterjee, AB	1
Bellinger, CR	1
Haponik, E	1
Arisaka, H	1
Sakuraba, S	1
Kobayashi, R	1
Kitahama, H	1
Nishida, N	1
Furuya, M	1
Yoshida, K	1
Glidewell, RN	1
Orr, WC	1
Imes, N	1
Patel, A	1
Davidson, M	1
Tran, MC	1
Quraishi, H	1
Schoenberg, C	1
Sant, M	1
Lin, A	1
Sun, X	1
Horng, HC	1
Ho, MT	1
Huang, CH	1
Yeh, CC	1
Cherng, CH	1
Fyneface-Ogan, S	1
Abam, DS	1
Numbere, C	1
Cillo, JE	1
Finn, R	1
Miller, RJ	1
Gerhardt, MA	1
Waters, KA	1
McBrien, F	1
Stewart, P	1
Hinder, M	1
Wharton, S	1

Trial	Phase	Enrollment	Study Type	Start Date	Status
Evaluation of Perioperative Usage of Ketorolac on Postoperative Pain Reduction in Pediatric Patients With Adenotonsillectom[NCT05074056]	Phase 4	200 participants (Anticipated)	Interventional	2022-02-08	Recruiting
Fentanyl Test Results and Its Association With Morphine Requirements in Children With Obstructive Sleep Apnea Syndrome After Adenotonsillectomy[NCT02484222]		80 participants (Actual)	Observational	2015-09-30	Completed
Effect of Dexmedetomidine on Recovery Profiles of Elderly Patients[NCT01851005]		120 participants (Actual)	Interventional	2013-05-31	Completed
Opioid-Free Versus Transitional Anesthetic With Opioids From Tonsillectomy[NCT04528173]	Phase 4	550 participants (Anticipated)	Interventional	2020-07-22	Recruiting
The Effect of Different Dose of Dexmedetomidine Combined With Hydromorphone in Children With Tonsillectomy and Adenoidectomy[NCT03760809]	Phase 4	130 participants (Actual)	Interventional	2019-01-04	Completed
A Randomized, Double-Blinded, Placebo Controlled Trial Using Single Dose Dexmedetomidine In The Treatment Of Pain In Patients Undergoing Cleft Palate Repair[NCT02915042]	Phase 4	0 participants (Actual)	Interventional	2017-12-31	Withdrawn (stopped due to Recruitment concerns)
Caudal Versus Intravenous Magnesium Sulfate In The Prevention OF Emergence Agitation After Sevoflurane Anesthesia For Lower Abdominal Surgeries In Children.[NCT03846284]		93 participants (Actual)	Interventional	2017-10-08	Active, not recruiting
Evaluation of the Postoperative Agitation Prevention and Analgesic Efficacy of Perioperative Dexmedetomidine Infusion in a Pediatric Patient Group to Undergo Tonsillectomy and Adenoidectomy[NCT05986942]		80 participants (Actual)	Observational [Patient Registry]	2023-10-09	Completed
Effect of Dexmedetomidine Infusion for Postoperative Outcome and Smooth Emergence After Thyroidectomy[NCT02412150]		139 participants (Actual)	Interventional	2014-04-30	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

The number of participants who were light consumers of morphine as identified by the Fentanyl Test，we want to know the accurate of the test.The light consumers are the children of who used total morphine <50 μg/kg. (NCT02484222)
Timeframe: average 1 hour from extubation

Article	Year
Impact of short-acting vs. standard anaesthetic agents on obstructive sleep apnoea: a randomised, controlled, triple-blind trial. Anaesthesia, 2021, Volume: 76, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intraveno	2021
Association between fentanyl test results and rescue morphine requirements in children after adenotonsillectomy. Journal of anesthesia, 2018, Volume: 32, Issue:1 Topics: Adenoidectomy; Airway Extubation; Child; Child, Preschool; Female; Fentanyl; Humans; Male; Morphine;	2018
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. Anesthesia and analgesia, 2010, Volume: 111, Issue:4 Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Child; Child, Presch	2010
Effects of OSA, inhalational anesthesia, and fentanyl on the airway and ventilation of children. Journal of applied physiology (Bethesda, Md. : 1985), 2002, Volume: 92, Issue:5 Topics: Analgesics, Opioid; Anesthetics, Inhalation; Apnea; Carbon Dioxide; Child; Child, Preschool; Drug Sy	2002

Article	Year
The performance of a postinduction fentanyl test in identifying severe obstructive sleep apnea syndrome. Paediatric anaesthesia, 2020, Volume: 30, Issue:1 Topics: Adenoidectomy; Anesthesia, General; Child; Child, Preschool; Female; Fentanyl; Humans; Male; Periope	2020
How Pediatric Anesthesiologists Manage Children with OSA Undergoing Tonsillectomy. The Annals of otology, rhinology, and laryngology, 2020, Volume: 129, Issue:1 Topics: Acetaminophen; Adenoidectomy; Airway Extubation; Analgesics; Anesthesiology; Anesthetics; Anti-Infla	2020
A 27-Year-Old Female on Chronic Opioid Therapy. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2015, Jun-15, Volume: 11, Issue:6 Topics: Adult; Analgesics, Opioid; Chronic Pain; Female; Fentanyl; Humans; Sleep Apnea, Obstructive	2015
Sedation for Bronchoscopy and Complications in Obese Patients. Respiration; international review of thoracic diseases, 2016, Volume: 92, Issue:3 Topics: Anesthetics, Intravenous; Body Mass Index; Bronchoscopy; Conscious Sedation; Female; Fentanyl; Human	2016
Perioperative management of obstructive sleep apnea with nasal continuous positive airway pressure. Anesthesia progress, 2008,Winter, Volume: 55, Issue:4 Topics: Aged; Anesthetics, Intravenous; Continuous Positive Airway Pressure; Critical Care; Female; Fentanyl	2008
Acetazolamide as an adjunct to CPAP treatment: a case of complex sleep apnea in a patient on long-acting opioid therapy. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2009, Feb-15, Volume: 5, Issue:1 Topics: Acetazolamide; Administration, Cutaneous; Administration, Oral; Adult; Analgesics, Opioid; Carbonic	2009
Negative pressure pulmonary edema following naloxone administration in a patient with fentanyl-induced respiratory depression. Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists, 2010, Volume: 48, Issue:3 Topics: Fentanyl; Humans; Male; Naloxone; Narcotic Antagonists; Pulmonary Edema; Respiratory Insufficiency;	2010
Anaesthetic management of a super morbidly obese patient for total abdominal hysterectomy: a few more lessons to learn. African health sciences, 2012, Volume: 12, Issue:2 Topics: Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Female; Fentanyl; Humans; Hysterectomy; Middle	2012
Hemodynamics and oxygen saturation during intravenous sedation for office-based laser-assisted uvuloplasty. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2005, Volume: 63, Issue:6 Topics: Ambulatory Surgical Procedures; Anesthesia, Dental; Anesthetics, Intravenous; Blood Pressure; Consci	2005
Uvular edema secondary to snoring under deep sedation. Anesthesia progress, 2006,Spring, Volume: 53, Issue:1 Topics: Anesthetics, Dissociative; Anesthetics, Intravenous; Arm; Brachial Plexus; Edema; Fentanyl; Humans;	2006

fentanyl and Sleep Apnea, Obstructive

Research Excerpts

Research

Studies (15)

Authors

Clinical Trials (9)

Trial Overview

Trial Outcomes

Number of Participants Who Were Light Consumers of Morphine as Identified by the Fentanyl Test

Number of Participants With Pulse Oxygen Saturation Less Than 95 Percent

Post-operative Nausea and Vomiting

Rescue Morphine Requirement

Reviews

Trials

Other Studies