fentanyl has been researched along with ST Elevation Myocardial Infarction in 4 studies
Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.
ST Elevation Myocardial Infarction: A clinical syndrome defined by MYOCARDIAL ISCHEMIA symptoms; persistent elevation in the ST segments of the ELECTROCARDIOGRAM; and release of BIOMARKERS of myocardial NECROSIS (e.g., elevated TROPONIN levels). ST segment elevation in the ECG is often used in determining the treatment protocol (see also NON-ST ELEVATION MYOCARDIAL INFARCTION).
| Excerpt | Relevance | Reference |
|---|---|---|
| "IV Lidocaine did not meet the criteria for non-inferiority with lower prehospital pain reduction than fentanyl but was safe and better tolerated as analgesia in ST-elevation myocardial infarction (STEMI)." | 5.69 | LidocAine Versus Opioids In MyocarDial infarction: the AVOID-2 randomized controlled trial. ( Andrew, E; Bernard, S; Brennan, A; Dinh, D; Fernando, H; Lefkovits, J; Milne, C; Myles, PS; Nehme, Z; O'Brien, J; Peter, K; Smith, K; Stephenson, M; Stub, D; Taylor, AJ, 2023) |
| "Patients with STEMI who required analgesia were randomly assigned in a 1:1 ratio to treatment with intravenous fentanyl or morphine after ticagrelor loading dose (LD) administration." | 3.11 | Comparative effects of fentanyl versus morphine on platelet inhibition induced by ticagrelor in patients with ST-segment elevation myocardial infarction: Full results of the PERSEUS randomized trial. ( Carbone, F; Degrauwe, S; Iglesias, JF; Lauriers, N; Masci, PG; Valgimigli, M, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 3 (75.00) | 2.80 |
| Authors | Studies |
|---|---|
| Iglesias, JF | 3 |
| Valgimigli, M | 3 |
| Carbone, F | 2 |
| Lauriers, N | 3 |
| Masci, PG | 2 |
| Degrauwe, S | 3 |
| Fernando, H | 2 |
| Nehme, Z | 2 |
| Milne, C | 2 |
| O'Brien, J | 2 |
| Bernard, S | 2 |
| Stephenson, M | 2 |
| Myles, PS | 2 |
| Lefkovits, J | 2 |
| Peter, K | 2 |
| Brennan, A | 2 |
| Dinh, D | 2 |
| Andrew, E | 2 |
| Taylor, AJ | 2 |
| Smith, K | 2 |
| Stub, D | 2 |
| Giorgio Masci, P | 1 |
| Roffi, M | 1 |
| Muller, O | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of Analgesia With Fentanyl and Morphine on Platelet Inhibition After Pre-hospital Ticagrelor Administration in Patients With ST-segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention[NCT02531165] | 38 participants (Actual) | Interventional | 2015-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for fentanyl and ST Elevation Myocardial Infarction
| Article | Year |
|---|---|
Comparative effects of fentanyl versus morphine on platelet inhibition induced by ticagrelor in patients with ST-segment elevation myocardial infarction: Full results of the PERSEUS randomized trial.
Topics: Fentanyl; Humans; Morphine; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Pla | 2022 |
LidocAine Versus Opioids In MyocarDial infarction: the AVOID-2 randomized controlled trial.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Fentanyl; Humans; Lidocaine; Pain; Prospective Studies | 2023 |
LidocAine Versus Opioids In MyocarDial infarction: the AVOID-2 randomized controlled trial.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Fentanyl; Humans; Lidocaine; Pain; Prospective Studies | 2023 |
LidocAine Versus Opioids In MyocarDial infarction: the AVOID-2 randomized controlled trial.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Fentanyl; Humans; Lidocaine; Pain; Prospective Studies | 2023 |
LidocAine Versus Opioids In MyocarDial infarction: the AVOID-2 randomized controlled trial.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Fentanyl; Humans; Lidocaine; Pain; Prospective Studies | 2023 |
Effects of Fentanyl Versus Morphine on Ticagrelor-Induced Platelet Inhibition in Patients With ST-Segment Elevation Myocardial Infarction: The PERSEUS Randomized Trial.
Topics: Administration, Oral; Analgesics, Opioid; Blood Platelets; Drug Interactions; Fentanyl; Humans; Morp | 2020 |
Influence of intravenous fentanyl compared with morphine on ticagrelor absorption and platelet inhibition in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: rationale and design of the PERSEU
Topics: Administration, Intravenous; Administration, Oral; Analgesics, Opioid; Blood Platelets; Drug Interac | 2019 |