fentanyl has been researched along with Retrolental Fibroplasia in 13 studies
Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study aimed to compare the efficacy of intravenous, intranasal fentanyl and oral sucrose in reducing the pain response during retinopathy of prematurity examinations using premature infant pain profile (PIPP) scores." | 9.69 | Effects of fentanyl and sucrose on pain in retinopathy examinations with pain scale, near-infrared spectroscopy, and ultrasonography: a randomized trial. ( Arman, D; Cömert, S; Gül, A; Kara, N; Seymen, Z, 2023) |
| "To investigate if intravenous fentanyl or intravenous ketamine can provide adequate analgesia in preterm infants undergoing laser photocoagulation for retinopathy of prematurity (ROP)." | 9.41 | 'NOPAIN-ROP' trial: Intravenous fentanyl and intravenous ketamine for pain relief during laser photocoagulation for retinopathy of prematurity (ROP) in preterm infants: A randomised trial. ( Agarwal, R; Chandra, P; Deorari, A; Madathil, S; Sankar, MJ; Thomas, D; Thukral, A, 2021) |
| "To compare the efficacy of low dose fentanyl infusion and 24% oral sucrose in providing optimal pain relief during laser for retinopathy of prematurity (ROP), we enrolled fifty-eight spontaneously breathing preterm infants undergoing laser." | 9.34 | Low dose fentanyl infusion versus 24% oral sucrose for pain management during laser treatment for retinopathy of prematurity-an open label randomized clinical trial. ( Agarwal, R; Chandra, P; Kulkarni, S; Sankar, MJ; Sethi, A; Thukral, A, 2020) |
| "To study the efficacy of intranasal fentanyl as an adjunct for pain management during screening for retinopathy of prematurity (ROP) in preterm infants." | 9.34 | Intranasal fentanyl for pain management during screening for retinopathy of prematurity in preterm infants: a randomized controlled trial. ( Agashe, P; Balasubramanian, H; Doshi, A; Kabra, NS; Sindhur, M; Srinivasan, L, 2020) |
| "To compare complication rates of the analgesics fentanyl and morphine in preterm infants undergoing laser therapy for retinopathy of prematurity (ROP)." | 7.79 | Comparison of fentanyl and morphine in laser surgery for retinopathy of prematurity. ( Gordon, K; Lee, TJ; Örge, FH; Walsh, M, 2013) |
| "This study aimed to compare the efficacy of intravenous, intranasal fentanyl and oral sucrose in reducing the pain response during retinopathy of prematurity examinations using premature infant pain profile (PIPP) scores." | 5.69 | Effects of fentanyl and sucrose on pain in retinopathy examinations with pain scale, near-infrared spectroscopy, and ultrasonography: a randomized trial. ( Arman, D; Cömert, S; Gül, A; Kara, N; Seymen, Z, 2023) |
| "Propofol was initially infused as a slow bolus of 2-4 mg/kg and then continuously during the entire procedure, at 4 mg/kg/hour, increasing the dosage to 6 mg/kg/hour if sedation was not achieved." | 5.51 | Propofol and fentanyl sedation for laser treatment of retinopathy of prematurity to avoid intubation. ( Auriti, C; Bersani, I; Capolupo, I; Catena, G; Di Ciommo, V; Di Pede, A; Dotta, A; Lipreri, A; Lozzi, S; Piersigilli, F; Sgrò, S, 2019) |
| "To investigate if intravenous fentanyl or intravenous ketamine can provide adequate analgesia in preterm infants undergoing laser photocoagulation for retinopathy of prematurity (ROP)." | 5.41 | 'NOPAIN-ROP' trial: Intravenous fentanyl and intravenous ketamine for pain relief during laser photocoagulation for retinopathy of prematurity (ROP) in preterm infants: A randomised trial. ( Agarwal, R; Chandra, P; Deorari, A; Madathil, S; Sankar, MJ; Thomas, D; Thukral, A, 2021) |
| " Cardiopulmonary instability was more common, and hypothermia was less common in the sedation groups of pentazocine/midazolam and fentanyl/midazolam, compared to the general anesthesia group of air/oxygen/sevoflurane (AOS)." | 5.41 | Safety profile of anesthetic modalities during laser treatment for retinopathy of prematurity: a systematic review. ( Arvanitaki, Z; Gavriilidou, A; Haidich, AB; Mataftsi, A; Seliniotaki, AK; Ziakas, N, 2023) |
| " We are uncertain whether tramadol reduces mortality compared to placebo; none of the studies reported pain scores, major neurodevelopmental disability, cognitive and educational outcomes in children older than five years old, retinopathy of prematurity, or intraventricular hemorrhage." | 5.41 | Systemic opioids versus other analgesics and sedatives for postoperative pain in neonates. ( Borges do Nascimento, IJ; Bruschettini, M; Kinoshita, M; Stempel, KS, 2023) |
| "To compare the efficacy of low dose fentanyl infusion and 24% oral sucrose in providing optimal pain relief during laser for retinopathy of prematurity (ROP), we enrolled fifty-eight spontaneously breathing preterm infants undergoing laser." | 5.34 | Low dose fentanyl infusion versus 24% oral sucrose for pain management during laser treatment for retinopathy of prematurity-an open label randomized clinical trial. ( Agarwal, R; Chandra, P; Kulkarni, S; Sankar, MJ; Sethi, A; Thukral, A, 2020) |
| "To study the efficacy of intranasal fentanyl as an adjunct for pain management during screening for retinopathy of prematurity (ROP) in preterm infants." | 5.34 | Intranasal fentanyl for pain management during screening for retinopathy of prematurity in preterm infants: a randomized controlled trial. ( Agashe, P; Balasubramanian, H; Doshi, A; Kabra, NS; Sindhur, M; Srinivasan, L, 2020) |
| " Further research is required to determine whether the use of nitrous oxide has a role, and to develop a safe and effective analgesic strategy to fully ameliorate the pain of ROP screening." | 5.22 | Analgesia for retinopathy of prematurity screening: A systematic review. ( Hamilton, DL; Hassan, R; Savant, SV; Thirunavukarasu, AJ, 2022) |
| "To compare complication rates of the analgesics fentanyl and morphine in preterm infants undergoing laser therapy for retinopathy of prematurity (ROP)." | 3.79 | Comparison of fentanyl and morphine in laser surgery for retinopathy of prematurity. ( Gordon, K; Lee, TJ; Örge, FH; Walsh, M, 2013) |
| "Propofol was initially infused as a slow bolus of 2-4 mg/kg and then continuously during the entire procedure, at 4 mg/kg/hour, increasing the dosage to 6 mg/kg/hour if sedation was not achieved." | 1.51 | Propofol and fentanyl sedation for laser treatment of retinopathy of prematurity to avoid intubation. ( Auriti, C; Bersani, I; Capolupo, I; Catena, G; Di Ciommo, V; Di Pede, A; Dotta, A; Lipreri, A; Lozzi, S; Piersigilli, F; Sgrò, S, 2019) |
| " Vital signs before and after dosing were not significantly different." | 1.51 | Intranasal midazolam and fentanyl for procedural sedation and analgesia in infants in the neonatal intensive care unit. ( Bidegain, M; Cotten, CM; Fisher, K; Goldberg, RN; Greenberg, RG; Hornik, CD; Ku, LC; Simmons, C; Smith, PB, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 5 (38.46) | 24.3611 |
| 2020's | 7 (53.85) | 2.80 |
| Authors | Studies |
|---|---|
| Madathil, S | 1 |
| Thomas, D | 1 |
| Chandra, P | 2 |
| Agarwal, R | 2 |
| Sankar, MJ | 2 |
| Thukral, A | 2 |
| Deorari, A | 1 |
| Thirunavukarasu, AJ | 1 |
| Hassan, R | 1 |
| Savant, SV | 1 |
| Hamilton, DL | 1 |
| Gavriilidou, A | 1 |
| Seliniotaki, AK | 1 |
| Arvanitaki, Z | 1 |
| Ziakas, N | 1 |
| Haidich, AB | 1 |
| Mataftsi, A | 1 |
| Kinoshita, M | 1 |
| Stempel, KS | 1 |
| Borges do Nascimento, IJ | 1 |
| Bruschettini, M | 1 |
| Kara, N | 1 |
| Arman, D | 1 |
| Seymen, Z | 1 |
| Gül, A | 1 |
| Cömert, S | 1 |
| Sethi, A | 1 |
| Kulkarni, S | 1 |
| Sindhur, M | 1 |
| Balasubramanian, H | 1 |
| Srinivasan, L | 1 |
| Kabra, NS | 1 |
| Agashe, P | 1 |
| Doshi, A | 1 |
| Piersigilli, F | 1 |
| Di Pede, A | 1 |
| Catena, G | 1 |
| Lozzi, S | 1 |
| Auriti, C | 1 |
| Bersani, I | 1 |
| Capolupo, I | 1 |
| Lipreri, A | 1 |
| Di Ciommo, V | 1 |
| Dotta, A | 1 |
| Sgrò, S | 1 |
| Ku, LC | 1 |
| Simmons, C | 1 |
| Smith, PB | 1 |
| Greenberg, RG | 1 |
| Fisher, K | 1 |
| Hornik, CD | 1 |
| Cotten, CM | 1 |
| Goldberg, RN | 1 |
| Bidegain, M | 1 |
| Örge, FH | 1 |
| Lee, TJ | 1 |
| Walsh, M | 1 |
| Gordon, K | 1 |
| Sato, Y | 1 |
| Oshiro, M | 1 |
| Takemoto, K | 1 |
| Hosono, H | 1 |
| Saito, A | 1 |
| Kondo, T | 1 |
| Aizu, K | 1 |
| Matsusawa, M | 1 |
| Futamura, Y | 1 |
| Asami, T | 1 |
| Terasaki, H | 1 |
| Hayakawa, M | 1 |
| Jiang, JB | 1 |
| Strauss, R | 1 |
| Luo, XQ | 1 |
| Nie, C | 1 |
| Wang, YL | 1 |
| Zhang, JW | 1 |
| Zhang, ZW | 1 |
| Allegaert, K | 1 |
| Tibboel, D | 1 |
| Naulaers, G | 1 |
| Tison, D | 1 |
| De Jonge, A | 1 |
| Van Dijk, M | 1 |
| Vanhole, C | 1 |
| Devlieger, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Intranasal Dexmedetomidine for Pain Management During Screening for Retinopathy of Prematurity: A Crossover Randomized Controlled Trial[NCT06067958] | Phase 3 | 30 participants (Anticipated) | Interventional | 2024-01-31 | Not yet recruiting | ||
| [NCT01872871] | 80 participants (Anticipated) | Interventional | 2013-01-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for fentanyl and Retrolental Fibroplasia
| Article | Year |
|---|---|
Analgesia for retinopathy of prematurity screening: A systematic review.
Topics: Acetaminophen; Analgesia; Fentanyl; Humans; Infant, Newborn; Nitrous Oxide; Pain; Pain Measurement; | 2022 |
Safety profile of anesthetic modalities during laser treatment for retinopathy of prematurity: a systematic review.
Topics: Anesthetics; Child; Fentanyl; Humans; Hypothermia; Infant; Infant, Newborn; Ketamine; Lasers; Midazo | 2023 |
Systemic opioids versus other analgesics and sedatives for postoperative pain in neonates.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Cerebral Hemorrhage; Child; Child, Preschool; Fentany | 2023 |
5 trials available for fentanyl and Retrolental Fibroplasia
| Article | Year |
|---|---|
'NOPAIN-ROP' trial: Intravenous fentanyl and intravenous ketamine for pain relief during laser photocoagulation for retinopathy of prematurity (ROP) in preterm infants: A randomised trial.
Topics: Fentanyl; Humans; Infant; Infant, Newborn; Infant, Premature; Ketamine; Lasers; Light Coagulation; P | 2021 |
Effects of fentanyl and sucrose on pain in retinopathy examinations with pain scale, near-infrared spectroscopy, and ultrasonography: a randomized trial.
Topics: Fentanyl; Humans; Infant; Infant, Newborn; Oxygen; Pain; Pain Measurement; Retinopathy of Prematurit | 2023 |
Low dose fentanyl infusion versus 24% oral sucrose for pain management during laser treatment for retinopathy of prematurity-an open label randomized clinical trial.
Topics: Administration, Oral; Anesthesia, General; Crying; Dose-Response Relationship, Drug; Female; Fentany | 2020 |
Intranasal fentanyl for pain management during screening for retinopathy of prematurity in preterm infants: a randomized controlled trial.
Topics: Fentanyl; Humans; Infant; Infant, Newborn; Infant, Premature; Pain Management; Pain Measurement; Ret | 2020 |
Systematic evaluation of pain in neonates: effect on the number of intravenous analgesics prescribed.
Topics: Acetaminophen; Analgesics; Cohort Studies; Drug Utilization; Fentanyl; Humans; Infant, Newborn; Infa | 2003 |
5 other studies available for fentanyl and Retrolental Fibroplasia
| Article | Year |
|---|---|
Propofol and fentanyl sedation for laser treatment of retinopathy of prematurity to avoid intubation.
Topics: Anesthesia, General; Female; Fentanyl; Gestational Age; Humans; Infant; Infant, Newborn; Infant, Pre | 2019 |
Intranasal midazolam and fentanyl for procedural sedation and analgesia in infants in the neonatal intensive care unit.
Topics: Administration, Intranasal; Analgesics, Opioid; Arterial Pressure; Bradycardia; Catheterization, Per | 2019 |
Comparison of fentanyl and morphine in laser surgery for retinopathy of prematurity.
Topics: Analgesics, Opioid; Anesthetics, Intravenous; Body Temperature; Female; Fentanyl; Humans; Infant, Ne | 2013 |
Multicenter observational study comparing sedation/analgesia protocols for laser photocoagulation treatment of retinopathy of prematurity.
Topics: Administration, Inhalation; Cohort Studies; Conscious Sedation; Female; Fentanyl; Humans; Infant, Ne | 2015 |
Anaesthesia modalities during laser photocoagulation for retinopathy of prematurity: a retrospective, longitudinal study.
Topics: Adjuvants, Anesthesia; Administration, Ophthalmic; Anesthesia, General; Anesthesia, Local; Deep Seda | 2017 |