Page last updated: 2024-10-27

fentanyl and Respiratory Distress Syndrome, Newborn

fentanyl has been researched along with Respiratory Distress Syndrome, Newborn in 24 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Respiratory Distress Syndrome, Newborn: A condition of the newborn marked by DYSPNEA with CYANOSIS, heralded by such prodromal signs as dilatation of the alae nasi, expiratory grunt, and retraction of the suprasternal notch or costal margins, mostly frequently occurring in premature infants, children of diabetic mothers, and infants delivered by cesarean section, and sometimes with no apparent predisposing cause.

Research Excerpts

ExcerptRelevanceReference
"We report here the case of an infant who developed life-threatening rigid-chest syndrome after receiving an accidental overdose of methadone."7.76Methadone-induced rigid-chest syndrome after substantial overdose. ( Hack, RA; Lynch, RE, 2010)
"We report here the case of an infant who developed life-threatening rigid-chest syndrome after receiving an accidental overdose of methadone."3.76Methadone-induced rigid-chest syndrome after substantial overdose. ( Hack, RA; Lynch, RE, 2010)
"Fentanyl application was not associated with gallbladder sludge/stones, gallbladder hydrops, hyperbilirubinemia or prolonged meconium release."2.72Prospective sonographic evaluation of fentanyl side effects on the neonatal gallbladder. ( Benz-Bohm, G; Roth, B; Schmidt, B; Stützer, H, 2006)
" Vital signs before and after dosing were not significantly different."1.51Intranasal midazolam and fentanyl for procedural sedation and analgesia in infants in the neonatal intensive care unit. ( Bidegain, M; Cotten, CM; Fisher, K; Goldberg, RN; Greenberg, RG; Hornik, CD; Ku, LC; Simmons, C; Smith, PB, 2019)
"Morphine was associated with a minimal incremental cost-effectiveness ratio of USD 135 per additional case of successful pain relief over fentanyl."1.51Clinical and Economic Analysis of Morphine Versus Fentanyl in Managing Ventilated Neonates With Respiratory Distress Syndrome in the Intensive Care Setting. ( AbouNahia, F; Abushanab, D; Al-Badriyeh, D; Alsoukhni, O, 2019)
"Infant delirium is an under-recognized clinical entity in neonatal intensive care, and earlier identification and treatment could minimize morbidities associated with this condition."1.46A case of infant delirium in the neonatal intensive care unit. ( Bidegain, M; Cotten, CM; Edwards, LE; Hornik, CD; Hutchison, LB; Smith, PB, 2017)
"Less fentanyl was administered during NAVA, as opposed to PRVC (p < 0."1.42Neurally adjusted ventilatory assist in preterm neonates with acute respiratory failure. ( Alemani, M; Berni, P; Bona, G; Cammarota, G; Colombo, D; Conti, G; Cosi, G; De Luca, D; Della Corte, F; Ferrero, F; Longhini, F; Navalesi, P, 2015)
"We observed chest wall rigidity in 8 patients after low dosage of fentanyl (3-5 microg/kg body weight)."1.31Fentanyl-induced chest wall rigidity and laryngospasm in preterm and term infants. ( Bartmann, P; Fahnenstich, H; Kau, N; Steffan, J, 2000)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.17)18.7374
1990's7 (29.17)18.2507
2000's3 (12.50)29.6817
2010's10 (41.67)24.3611
2020's3 (12.50)2.80

Authors

AuthorsStudies
Bhattacharya, S1
Read, B1
Miller, M1
da Silva, O1
Sk, H1
Saha, B1
Mukherjee, S1
Hazra, A1
Bensouda, B1
St-Hilaire, M1
Mandel, R1
Barbier, A1
Ali, N1
Ku, LC1
Simmons, C1
Smith, PB2
Greenberg, RG1
Fisher, K1
Hornik, CD2
Cotten, CM2
Goldberg, RN1
Bidegain, M2
Abushanab, D1
Alsoukhni, O1
AbouNahia, F1
Al-Badriyeh, D1
Aguar, M1
Cernada, M1
Brugada, M1
Gimeno, A1
Gutierrez, A1
Vento, M1
Molgat-Seon, Y1
Daboval, T1
Chou, S1
Jay, O1
Longhini, F1
Ferrero, F1
De Luca, D1
Cosi, G1
Alemani, M1
Colombo, D1
Cammarota, G1
Berni, P1
Conti, G1
Bona, G1
Della Corte, F1
Navalesi, P1
Elmekkawi, A1
Abdelgadir, D1
Van Dyk, J1
Choudhury, J1
Dunn, M1
Edwards, LE1
Hutchison, LB1
Schmidt, B2
Adelmann, C1
Stützer, H2
Welzing, L1
Hünseler, C1
Kribs, A1
Roth, B3
Lynch, RE1
Hack, RA1
Harlos, MS1
Stenekes, S1
Lambert, D1
Hohl, C1
Chochinov, HM1
Benz-Bohm, G1
Desprats, R1
Mandry, J1
Grandjean, H1
Amar, B1
Pontonnier, G1
Lareng, L1
Orsini, AJ1
Leef, KH1
Costarino, A1
Dettorre, MD1
Stefano, JL1
Templeton, KE1
Ramet, J1
Clybouw, C1
Benatar, A1
Hachimi-Idrissi, S1
Corne, L1
Fahnenstich, H1
Steffan, J1
Kau, N1
Bartmann, P1
Das, UG1
Sasidharan, P1
Burtin, P1
Daoud, P1
Jacqz-Aigrain, E1
Mussat, P1
Moriette, G1
Schlünder, C1
Houben, F1
Hartwig, S1
Theisohn, M1
Goldstein, RF1
Brazy, JE1
Nightingale, SL1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Breathing Pattern Variability in Preterm Infants: Effect of Non-invasive Neurally Adjusted Ventilatory Assist (NAVA-NIV) Versus Nasal Intermittent Positive Pressure Ventilation (PC-NIV), a Crossover Study[NCT04000568]25 participants (Actual)Observational2019-05-02Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

5 trials available for fentanyl and Respiratory Distress Syndrome, Newborn

ArticleYear
Premedication with Fentanyl for Less Invasive Surfactant Application (LISA): A Randomized Controlled Trial.
    Journal of tropical pediatrics, 2022, 02-03, Volume: 68, Issue:2

    Topics: Fentanyl; Humans; Infant; Infant, Newborn; Infant, Premature; Intubation, Intratracheal; Premedicati

2022
Comparison of sufentanil versus fentanyl in ventilated term neonates.
    Klinische Padiatrie, 2010, Volume: 222, Issue:2

    Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Arousal; Dose-Response Relationship, Drug; Double

2010
Prospective sonographic evaluation of fentanyl side effects on the neonatal gallbladder.
    European journal of clinical pharmacology, 2006, Volume: 62, Issue:10

    Topics: Age Factors; Anesthetics, Intravenous; Bilirubin; Birth Weight; Data Interpretation, Statistical; Fe

2006
[Peridural analgesia during labor: comparative study of a fentanyl-marcaine combination and marcaine alone].
    Journal de gynecologie, obstetrique et biologie de la reproduction, 1983, Volume: 12, Issue:8

    Topics: Anesthesia, Epidural; Blood Pressure; Bupivacaine; Drug Combinations; Drug Eruptions; Drug Evaluatio

1983
Routine use of fentanyl infusions for pain and stress reduction in infants with respiratory distress syndrome.
    The Journal of pediatrics, 1996, Volume: 129, Issue:1

    Topics: Analgesics, Opioid; Double-Blind Method; Fentanyl; Heart Rate; Humans; Infant Behavior; Infant, Newb

1996

Other Studies

19 other studies available for fentanyl and Respiratory Distress Syndrome, Newborn

ArticleYear
Impact of Catheter Choice on Procedural Success of Minimally Invasive Surfactant Therapy.
    American journal of perinatology, 2023, Volume: 40, Issue:11

    Topics: Catheters; Fentanyl; Humans; Infant, Newborn; Infant, Premature; Pulmonary Surfactants; Respiratory

2023
Implementation of less-invasive surfactant administration in a Canadian neonatal intensive care unit.
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2022, Volume: 29, Issue:6

    Topics: Canada; Fentanyl; Humans; Infant; Infant, Newborn; Infant, Premature; Intensive Care Units, Neonatal

2022
Intranasal midazolam and fentanyl for procedural sedation and analgesia in infants in the neonatal intensive care unit.
    Journal of neonatal-perinatal medicine, 2019, Volume: 12, Issue:2

    Topics: Administration, Intranasal; Analgesics, Opioid; Arterial Pressure; Bradycardia; Catheterization, Per

2019
Clinical and Economic Analysis of Morphine Versus Fentanyl in Managing Ventilated Neonates With Respiratory Distress Syndrome in the Intensive Care Setting.
    Clinical therapeutics, 2019, Volume: 41, Issue:4

    Topics: Analgesia; Analgesics, Opioid; Cost-Benefit Analysis; Female; Fentanyl; Humans; Infant, Newborn; Inf

2019
Minimally invasive surfactant therapy with a gastric tube is as effective as the intubation, surfactant, and extubation technique in preterm babies.
    Acta paediatrica (Oslo, Norway : 1992), 2014, Volume: 103, Issue:6

    Topics: Adjuvants, Anesthesia; Airway Extubation; Atropine; Conscious Sedation; Continuous Positive Airway P

2014
Assessing neonatal heat balance and physiological strain in newborn infants nursed under radiant warmers in intensive care with fentanyl sedation.
    European journal of applied physiology, 2014, Volume: 114, Issue:12

    Topics: Analgesics, Opioid; Body Temperature; Body Temperature Regulation; Female; Fentanyl; Hot Temperature

2014
Neurally adjusted ventilatory assist in preterm neonates with acute respiratory failure.
    Neonatology, 2015, Volume: 107, Issue:1

    Topics: Anesthetics, Intravenous; Blood Gas Analysis; Comparative Effectiveness Research; Cross-Over Studies

2015
Use of naloxone to minimize extubation failure after premedication for INSURE procedure in preterm neonates.
    Journal of neonatal-perinatal medicine, 2016, Volume: 9, Issue:4

    Topics: Adjuvants, Anesthesia; Airway Extubation; Analgesics, Opioid; Atropine; Continuous Positive Airway P

2016
A case of infant delirium in the neonatal intensive care unit.
    Journal of neonatal-perinatal medicine, 2017, Volume: 10, Issue:1

    Topics: Amines; Analgesics, Opioid; Anti-Anxiety Agents; Cardiac Catheterization; Cyclohexanecarboxylic Acid

2017
Methadone-induced rigid-chest syndrome after substantial overdose.
    Pediatrics, 2010, Volume: 126, Issue:1

    Topics: Drug Administration Schedule; Drug Overdose; Fentanyl; Follow-Up Studies; Humans; Infant, Newborn; I

2010
Intranasal fentanyl in the palliative care of newborns and infants.
    Journal of pain and symptom management, 2013, Volume: 46, Issue:2

    Topics: Administration, Intranasal; Analgesics, Opioid; Female; Fentanyl; Humans; Infant, Newborn; Infant, P

2013
Analgesic use in the neonatal intensive care unit.
    The Journal of pediatrics, 1997, Volume: 130, Issue:3

    Topics: Analgesics, Opioid; Fentanyl; Humans; Infant, Newborn; Intensive Care, Neonatal; Research Design; Re

1997
Successful use of an intraosseous infusion in an 800 grams preterm infant.
    European journal of emergency medicine : official journal of the European Society for Emergency Medicine, 1998, Volume: 5, Issue:3

    Topics: Atropine; Bone Marrow; Cefotaxime; Dobutamine; Epinephrine; Fatal Outcome; Female; Fentanyl; Fluid T

1998
Fentanyl-induced chest wall rigidity and laryngospasm in preterm and term infants.
    Critical care medicine, 2000, Volume: 28, Issue:3

    Topics: Fentanyl; Humans; Hypercapnia; Hypoxia; Infant, Newborn; Infant, Premature; Laryngismus; Naloxone; N

2000
Bladder retention of urine as a result of continuous intravenous infusion of fentanyl: 2 case reports.
    Pediatrics, 2001, Volume: 108, Issue:4

    Topics: Analgesics, Opioid; Catheters, Indwelling; Female; Fentanyl; Humans; Infant, Newborn; Infusions, Int

2001
Hypotension with midazolam and fentanyl in the newborn.
    Lancet (London, England), 1991, Jun-22, Volume: 337, Issue:8756

    Topics: Drug Synergism; Drug Therapy, Combination; Fentanyl; Humans; Hypotension; Infant, Newborn; Midazolam

1991
[Analgesia and sedation in neonatal-pediatric intensive care].
    Klinische Wochenschrift, 1991, Volume: 69 Suppl 26

    Topics: Analgesia; Analgesics, Opioid; Child, Preschool; Conscious Sedation; Dose-Response Relationship, Dru

1991
Narcotic sedation stabilizes arterial blood pressure fluctuations in sick premature infants.
    Journal of perinatology : official journal of the California Perinatal Association, 1991, Volume: 11, Issue:4

    Topics: Blood Pressure; Conscious Sedation; Fentanyl; Humans; Infant, Newborn; Infant, Premature, Diseases;

1991
From the Food and Drug Administration.
    JAMA, 1990, Oct-10, Volume: 264, Issue:14

    Topics: Chronic Disease; Diet Fads; Dietary Fiber; Drug Combinations; Esophageal Stenosis; Fatty Alcohols; F

1990