fentanyl has been researched along with Respiration Disorders in 28 studies
Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.
Respiration Disorders: Diseases of the respiratory system in general or unspecified or for a specific respiratory disease not available.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study was designed to: 1) compare the safety and efficacy of intravenous fentanyl, intravenous fentanyl combined with midazolam, and intramuscular meperidine-promethazine-chlorpromazine (MPC) compound when used for painful emergency department (ED) procedures: and 2) to determine whether the addition of et-CO2 monitoring enabled earlier identification of respiratory depression in this population." | 5.08 | The value of end-tidal CO2 monitoring when comparing three methods of conscious sedation for children undergoing painful procedures in the emergency department. ( Berns, SD; Boenning, DA; Hart, LS; Houck, CS, 1997) |
| "Naloxone has shown its superiority to levallorphan." | 2.64 | [The effect of naloxone and levallorphane following fentanyl on the blood gases, EEG and psychodiagnostic tests (author's transl)]. ( Doenicke, A; Hug, P; Kugler, J; Laub, M; Zimmermann, W, 1978) |
| "To determine the incidence of adverse events related to an endoscopy sedation regimen that included propofol, delivered by general practitioner (GP) sedationists." | 1.31 | Sedation for endoscopy: the safe use of propofol by general practitioner sedationists. ( Chiragakis, L; Clarke, AC; Hillman, LC; Kaye, GL, 2002) |
| "Pruritus was observed in 29% of patients and was more common in diplegia than quadriplegia (48% vs 12." | 1.30 | Epidural analgesia in children with cerebral palsy. ( Brenn, BR; Brislin, RP; Rose, JB, 1998) |
| "Authors report a Launoise-Bensaude-Madelung disease case, in a 64 year old man, admitted to a Plastic Surgical Department for obesity, dysphonia, dysphagia, dyspnea." | 1.29 | [Anesthesiologic problems in patients with Launois-Bensaude-Madelung disease. Clinical case]. ( Bonfreschi, V; Cason, L; Da Broi, U; Osti, M; Parodi, PC; Pasetto, A; Riberti, C; Zauli, M, 1996) |
| "Alfentanil was compared with fentanyl in a double blind study of 90 female patients undergoing laparoscopic sterilizations." | 1.26 | Double-blind comparison of the postoperative respiratory depressant effects of alfentanil and fentanyl. ( Adam, A; Deen, L; Giezen, J; Helmers, JH; Van Leeuwen, L, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (50.00) | 18.7374 |
| 1990's | 9 (32.14) | 18.2507 |
| 2000's | 2 (7.14) | 29.6817 |
| 2010's | 3 (10.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Piskin, O | 1 |
| Altinsoy, B | 1 |
| Cimencan, M | 1 |
| Aydin, BG | 1 |
| Okyay, D | 1 |
| Kucukosman, G | 1 |
| Tascilar, O | 1 |
| Sarikaya, S | 1 |
| Ayoglu, H | 1 |
| Abushanab, DH | 1 |
| Alsoukhni, OA | 1 |
| Al-Badriyeh, D | 1 |
| Friedrich, S | 1 |
| Raub, D | 1 |
| Teja, BJ | 1 |
| Neves, SE | 1 |
| Thevathasan, T | 1 |
| Houle, TT | 1 |
| Eikermann, M | 1 |
| Godambe, SA | 1 |
| Elliot, V | 1 |
| Matheny, D | 1 |
| Pershad, J | 1 |
| Helmers, JH | 1 |
| Van Leeuwen, L | 1 |
| Adam, A | 1 |
| Giezen, J | 1 |
| Deen, L | 1 |
| Bovill, JG | 1 |
| Sebel, PS | 1 |
| Stanley, TH | 1 |
| Nilsson, C | 1 |
| Rosberg, B | 1 |
| Blanco, J | 1 |
| Blanco, E | 1 |
| Rodríguez, G | 1 |
| Castro, A | 1 |
| Alvarez, J | 1 |
| Da Broi, U | 1 |
| Zauli, M | 1 |
| Bonfreschi, V | 1 |
| Cason, L | 1 |
| Parodi, PC | 1 |
| Osti, M | 1 |
| Pasetto, A | 1 |
| Riberti, C | 1 |
| Hart, LS | 1 |
| Berns, SD | 1 |
| Houck, CS | 1 |
| Boenning, DA | 1 |
| Porter, J | 1 |
| Bonello, E | 1 |
| Reynolds, F | 1 |
| Brenn, BR | 1 |
| Brislin, RP | 1 |
| Rose, JB | 1 |
| Okuda, T | 1 |
| Wakita, K | 1 |
| Tsuchiya, N | 1 |
| Hatsuoka, K | 1 |
| Koga, Y | 1 |
| Kaetsu, I | 1 |
| Carrero Cardenal, EJ | 1 |
| Valero Castell, R | 1 |
| Roux Carmona, C | 1 |
| Lapena Bayo, C | 1 |
| Ortells Ribé, J | 1 |
| Artigas Rubio, X | 1 |
| Clark, JD | 1 |
| Edwards, T | 1 |
| Clarke, AC | 1 |
| Chiragakis, L | 1 |
| Hillman, LC | 1 |
| Kaye, GL | 1 |
| Dick, W | 1 |
| Milewski, P | 1 |
| Knoche, E | 1 |
| Traub, E | 1 |
| Bethlehem, BH | 1 |
| Florence, AM | 1 |
| Tigerstedt, I | 1 |
| Schaer, H | 1 |
| Baasch, K | 1 |
| Reist, F | 1 |
| Gattiker, R | 1 |
| Dimai, W | 1 |
| Berlin, J | 1 |
| Hossli, G | 1 |
| Hug, P | 1 |
| Kugler, J | 2 |
| Zimmermann, W | 1 |
| Laub, M | 1 |
| Doenicke, A | 2 |
| Grote, B | 1 |
| Gutzeit, M | 1 |
| Bromage, PR | 1 |
| Husain, I | 1 |
| El-Faqih, S | 1 |
| Bonsu, AK | 1 |
| Kadiwal, GH | 1 |
| Seraj, P | 1 |
| Jaffe, RS | 1 |
| Coalson, D | 1 |
| Owen, H | 1 |
| Brose, WG | 1 |
| Mahla, ME | 1 |
| White, SE | 1 |
| Moneta, MD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Intraoperative Fentanyl Dose on Postoperative Respiratory Complications[NCT03198208] | 183,396 participants (Actual) | Observational [Patient Registry] | 2007-01-01 | Active, not recruiting | |||
| Comparison of Two Methods Using Intranasal Lidocaine to Alleviate Discomfort Associated With Administration of Intranasal Midazolam in Children.[NCT03054844] | Phase 2 | 55 participants (Actual) | Interventional | 2017-04-03 | Completed | ||
| A Prospective Randomized Double Blind Evaluation of Ketamine/Propofol vs Ketamine Alone for Pediatric Extremity Fracture Reduction[NCT00490997] | Phase 4 | 140 participants (Actual) | Interventional | 2007-06-30 | Completed | ||
| Ketamine Versus Etomidate for Procedural Sedation for Pediatric Orthopedic Reductions[NCT00596050] | Phase 4 | 50 participants (Actual) | Interventional | 2006-08-31 | Completed | ||
| Ketofol Versus Fentofol for Procedural Sedation of Children 3 to 17 Years Old: a Double-Blind Randomized Controlled Trial[NCT02079090] | Phase 3 | 30 participants (Actual) | Interventional | 2014-07-31 | Completed | ||
| Opioid Free Versus Opioid Balanced Anesthesia in Middle Ear Surgery.[NCT03809949] | Phase 4 | 60 participants (Actual) | Interventional | 2019-01-16 | Completed | ||
| Efficacy of Intermittent Superficial Parasternal Intercostal Plane Block on Postoperative Pain Control in Patients Undergoing Cardiac Surgery With Median Sternotomy - EPOCH Randomized Clinical Trial[NCT06028126] | 310 participants (Anticipated) | Interventional | 2023-09-30 | Recruiting | |||
| A Randomised Control Trial to Determine Whether Intervention Based on a Microstream Capnography-based Ventilation Monitoring System Will Decrease Hypoxaemaia During Intravenous Sedation With Midazolam.[NCT01949012] | 190 participants (Actual) | Interventional | 2013-10-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
If my child needed medications to stay calm for a procedure, I would like to use these same medications again. (NCT03054844)
Timeframe: 1 minute
| Intervention | Participants (Count of Participants) |
|---|---|
| PREMED | 10 |
| PREMIX | 12 |
Cry duration was measured in seconds and defined as the time from onset of crying following administration of an IN medication until the cessation of crying sounds and/or tears. If a patient did not cry, the cry duration was zero (NCT03054844)
Timeframe: 10 minutes
| Intervention | seconds (Mean) |
|---|---|
| PREMED | 84 |
| PREMIX | 73 |
The Faces, Legs, Activity, Cry, Consolability (FLACC) scale is comprised of five criteria (face, legs, activity, cry, consolability), with a possible score of 0 to 2 units on a scale for each criteria and a possible total score of 0 to 10 units on a scale (0 meaning no pain, 10 meaning most pain). (NCT03054844)
Timeframe: 10 minutes
| Intervention | Units on a scale (Mean) |
|---|---|
| PREMED | 6.7 |
| PREMIX | 7 |
The Observational Scale of Behavioral Distress-Revised (OSBD-R) is an observational measure of pain and distress shown to have strong validity in children. The scale is an 8-factor, weighted observational scale used to measure distress associated with medical procedures, which has been validated in children and adults aged 1 to 20 years. The total Observational Scale of Behavioral Distress-Revised score is the sum of the scale scores for each phase, with each phase assigned a score from 0 to 23.5 units on a scale (0=no distress, 23.5=maximum distress), based on the frequency and types of behaviors observed during a predetermined number of 15-second intervals during each phase. There were four phases so the range of scores for the total OSBD-R was 0 to 94 units on a scale, with a higher score indicated a greater degree of distress. (NCT03054844)
Timeframe: 10 minutes
| Intervention | Units on a scale (Mean) |
|---|---|
| PREMED | 6.4 |
| PREMIX | 7 |
The Children's Hospital of Eastern Ontario Pain Scale (CHEOPS) utilizes six observational factors (cry, facial, verbal, torso, touch, and legs) to evaluate pain in young children and can be used to monitor the effectiveness of interventions for reducing the pain and discomfort of an intervention. This scale rates each behavior numerically, with a score of 4-6 units on a scale representing no pain, and a maximum score of 13 units on a scale representing (most pain perceived). (NCT03054844)
Timeframe: 10 minutes
| Intervention | Units on a scale (Mean) |
|---|---|
| PREMED | 10.6 |
| PREMIX | 10.5 |
I would like to use this method of administering intranasal midazolam and lidocaine again in the future (NCT03054844)
Timeframe: 1 minute
| Intervention | Participants (Count of Participants) |
|---|---|
| PREMED | 8 |
| PREMIX | 24 |
2 reviews available for fentanyl and Respiration Disorders
| Article | Year |
|---|---|
Evaluations of Morphine and Fentanyl for Mechanically Ventilated Patients With Respiratory Disorders in Intensive Care: A Systematic Review of Methodological Trends and Reporting Quality.
Topics: Analgesics, Opioid; Cost-Benefit Analysis; Critical Care; Data Accuracy; Fentanyl; Humans; Morphine; | 2019 |
Opioid analgesics in anesthesia: with special reference to their use in cardiovascular anesthesia.
Topics: Alfentanil; Alphaprodine; Analgesics, Opioid; Anesthesia, General; Animals; Awareness; Brain; Cardia | 1984 |
Opioid analgesics in anesthesia: with special reference to their use in cardiovascular anesthesia.
Topics: Alfentanil; Alphaprodine; Analgesics, Opioid; Anesthesia, General; Animals; Awareness; Brain; Cardia | 1984 |
Opioid analgesics in anesthesia: with special reference to their use in cardiovascular anesthesia.
Topics: Alfentanil; Alphaprodine; Analgesics, Opioid; Anesthesia, General; Animals; Awareness; Brain; Cardia | 1984 |
Opioid analgesics in anesthesia: with special reference to their use in cardiovascular anesthesia.
Topics: Alfentanil; Alphaprodine; Analgesics, Opioid; Anesthesia, General; Animals; Awareness; Brain; Cardia | 1984 |
9 trials available for fentanyl and Respiration Disorders
| Article | Year |
|---|---|
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
The value of end-tidal CO2 monitoring when comparing three methods of conscious sedation for children undergoing painful procedures in the emergency department.
Topics: Capnography; Carbon Dioxide; Child; Chlorpromazine; Conscious Sedation; Drug Combinations; Emergency | 1997 |
Effect of epidural fentanyl on neonatal respiration.
Topics: Adult; Analgesics, Opioid; Female; Fentanyl; Humans; Infant, Newborn; Injections, Spinal; Labor, Obs | 1998 |
[Our negative experience with meperidine for the prevention of coughing during cataract surgery].
Topics: Antitussive Agents; Cataract Extraction; Cough; Double-Blind Method; Fentanyl; Humans; Intraocular P | 1999 |
[Clinical studies on the usefulness of naloxone after short lasting anaesthesias with narcotic analgesics (author's transl)].
Topics: Analgesics, Opioid; Anesthesia, General; Dose-Response Relationship, Drug; Female; Fentanyl; Flunitr | 1978 |
[Respiratory depression after fentanyl and antagonism by naloxone (author's transl)].
Topics: Adolescent; Adult; Aged; Anesthesia, General; Fentanyl; Flunitrazepam; Humans; Meperidine; Middle Ag | 1978 |
[Naloxone reversal of fentanyl anaesthesia in major vascular surgery (author's transl)].
Topics: Anesthesia, General; Aorta; Blood Gas Analysis; Dose-Response Relationship, Drug; Fentanyl; Humans; | 1978 |
[The effect of naloxone and levallorphane following fentanyl on the blood gases, EEG and psychodiagnostic tests (author's transl)].
Topics: Adult; Arrhythmias, Cardiac; Blood Gas Analysis; Double-Blind Method; Fentanyl; Humans; Levallorphan | 1978 |
[The influence of doxapram in human on the respiratory depression by fentanyl (author's transl)].
Topics: Depression, Chemical; Doxapram; Drug Evaluation; Fentanyl; Humans; Respiration Disorders | 1978 |
17 other studies available for fentanyl and Respiration Disorders
| Article | Year |
|---|---|
The effect of bariatric anaesthesia on postoperative pulmonary functions.
Topics: Adult; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Bariatric Surgery; Bl | 2017 |
Effects of low-dose intraoperative fentanyl on postoperative respiratory complication rate: a pre-specified, retrospective analysis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anesthesia, General; Dose-Response R | 2019 |
Double-blind comparison of the postoperative respiratory depressant effects of alfentanil and fentanyl.
Topics: Adult; Alfentanil; Analgesics, Opioid; Anesthesia; Double-Blind Method; Female; Fentanyl; Hemodynami | 1982 |
Recurrence of respiratory depression following neurolept analgesia.
Topics: Adult; Atropine; Blood Pressure; Female; Fentanyl; Heart Rate; Humans; Intubation, Intratracheal; Ki | 1982 |
One year's experience with an acute pain service in a Spanish University Clinic hospital.
Topics: Academic Medical Centers; Analgesia, Epidural; Analgesia, Patient-Controlled; Bupivacaine; Fentanyl; | 1994 |
[Anesthesiologic problems in patients with Launois-Bensaude-Madelung disease. Clinical case].
Topics: Anesthesia, General; Fentanyl; Humans; Intubation, Intratracheal; Isoflurane; Lipomatosis, Multiple | 1996 |
Epidural analgesia in children with cerebral palsy.
Topics: Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Cerebral Palsy; Child; Con | 1998 |
[Prolonged antinociceptive effect of poly (DL-lactic acid)-fentanyl composites after their intrathecal injection in rats].
Topics: Analgesics, Opioid; Animals; Delayed-Action Preparations; Drug Carriers; Fentanyl; Injections, Spina | 1999 |
Severe respiratory depression in a patient with gastroparesis while receiving opioids for pain.
Topics: Administration, Cutaneous; Administration, Oral; Adult; Analgesics, Opioid; Fentanyl; Gastroparesis; | 1999 |
Sedation for endoscopy: the safe use of propofol by general practitioner sedationists.
Topics: Anesthetics, Combined; Anesthetics, Intravenous; Australia; Colonoscopy; Family Practice; Fentanyl; | 2002 |
Delayed respiratory depression with fentanyl.
Topics: Fentanyl; Humans; Respiration Disorders | 1979 |
Delayed respiratory depression after use of fentanyl.
Topics: Anesthesia; Fentanyl; Humans; Respiration Disorders | 1978 |
Reversal of fentanyl-induced narcotic depression with naloxone following general anaesthesia.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Drug Evaluation; Female; Fentanyl; Humans; Male; Middl | 1978 |
Critique of the Dornier HM3 lithotripter as a clinical algesimeter.
Topics: Analgesia, Epidural; Bupivacaine; Female; Fentanyl; Humans; Lithotripsy; Male; Pain; Pain Measuremen | 1990 |
Recurrent respiratory depression after alfentanil administration.
Topics: Alfentanil; Anesthesia, Intravenous; Fentanyl; Humans; Male; Middle Aged; Recurrence; Respiration Di | 1989 |
Delayed respiratory depression following alfentanil.
Topics: Alfentanil; Analgesics, Opioid; Fentanyl; Humans; Respiration Disorders; Time Factors | 1989 |
Delayed respiratory depression after alfentanil.
Topics: Adolescent; Adult; Alfentanil; Fentanyl; Humans; Male; Naloxone; Respiration Disorders; Respiration, | 1988 |