fentanyl has been researched along with Renal Colic in 8 studies
Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.
Renal Colic: A severe intermittent and spasmodic pain in the lower back radiating to the groin, scrotum, and labia which is most commonly caused by a kidney stone (RENAL CALCULUS) passing through the URETER or by other urinary track blockage. It is often associated with nausea, vomiting, fever, restlessness, dull pain, frequent urination, and HEMATURIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fentanyl is highly effective in controlling pain in patients with severe renal colic referring to the emergency department." | 9.34 | Atomized intranasal vs intravenous fentanyl in severe renal colic pain management: A randomized single-blinded clinical trial. ( Mirzaee, M; Nazemian, N; Torabi, M, 2020) |
| "The present study was conducted to compare the analgesic effect of intravenous fentanyl with that of intranasal ketamine in renal colic patients." | 9.34 | Comparing intranasal ketamine with intravenous fentanyl in reducing pain in patients with renal colic: A double-blind randomized clinical trial. ( Maleki Verki, M; Motamed, H; Mozafari, J; Sabouhi, A; Tirandaz, F, 2020) |
| "In this study, we aimed to compare the analgesic efficacy of intravenous dexketoprofen trometamol, fentanyl, and paracetamol in patients presenting to the emergency department with renal colic." | 9.27 | Comparison of IV dexketoprofen trometamol, fentanyl, and paracetamol in the treatment of renal colic in the ED: A randomized controlled trial. ( Al, B; Bogan, M; Can, B; Eren, SH; Kul, S; Murat Oktay, M; Sabak, M; Sunar, MM; Zengin, S, 2018) |
| "Intravenous ketorolac had better analgesic effects in renal colic patients compared with nebulized fentanyl." | 8.02 | Comparison of efficacy nebulized fentanyl with intravenous ketorolac for renal colic in patients over 12 years old. ( Astaraki, P; Kalantari, A; Rezaei, B; Salimi, R, 2021) |
| "To assess the effectiveness of nebulized fentanyl used for analgesia in renal colic." | 7.85 | A retrospective analysis of nebulized versus intravenous fentanyl for renal colic. ( Aygun, A; Bekar, O; Cicek, M; Erdem, E; Imamoglu, M; Karaca, Y; Sahin, A; Tatli, O; Turedi, S; Turkmen, S, 2017) |
| "Intranasal fentanyl seems to be efficient for analgesia in adult patients with renal colic." | 7.81 | Does intranasal fentanyl provide efficient analgesia for renal colic in adults? ( Bakkali, H; Belkouch, A; Belyamani, L; Chouaib, N; Elbouti, A; Rafai, M; Sirbou, R; Zidouh, S, 2015) |
| "Fentanyl is highly effective in controlling pain in patients with severe renal colic referring to the emergency department." | 5.34 | Atomized intranasal vs intravenous fentanyl in severe renal colic pain management: A randomized single-blinded clinical trial. ( Mirzaee, M; Nazemian, N; Torabi, M, 2020) |
| "The present study was conducted to compare the analgesic effect of intravenous fentanyl with that of intranasal ketamine in renal colic patients." | 5.34 | Comparing intranasal ketamine with intravenous fentanyl in reducing pain in patients with renal colic: A double-blind randomized clinical trial. ( Maleki Verki, M; Motamed, H; Mozafari, J; Sabouhi, A; Tirandaz, F, 2020) |
| "In this study, we aimed to compare the analgesic efficacy of intravenous dexketoprofen trometamol, fentanyl, and paracetamol in patients presenting to the emergency department with renal colic." | 5.27 | Comparison of IV dexketoprofen trometamol, fentanyl, and paracetamol in the treatment of renal colic in the ED: A randomized controlled trial. ( Al, B; Bogan, M; Can, B; Eren, SH; Kul, S; Murat Oktay, M; Sabak, M; Sunar, MM; Zengin, S, 2018) |
| "Intravenous ketorolac had better analgesic effects in renal colic patients compared with nebulized fentanyl." | 4.02 | Comparison of efficacy nebulized fentanyl with intravenous ketorolac for renal colic in patients over 12 years old. ( Astaraki, P; Kalantari, A; Rezaei, B; Salimi, R, 2021) |
| "To assess the effectiveness of nebulized fentanyl used for analgesia in renal colic." | 3.85 | A retrospective analysis of nebulized versus intravenous fentanyl for renal colic. ( Aygun, A; Bekar, O; Cicek, M; Erdem, E; Imamoglu, M; Karaca, Y; Sahin, A; Tatli, O; Turedi, S; Turkmen, S, 2017) |
| "Intranasal fentanyl seems to be efficient for analgesia in adult patients with renal colic." | 3.81 | Does intranasal fentanyl provide efficient analgesia for renal colic in adults? ( Bakkali, H; Belkouch, A; Belyamani, L; Chouaib, N; Elbouti, A; Rafai, M; Sirbou, R; Zidouh, S, 2015) |
| "The introduction of CPOE is associated with an increase in ketorolac use for ED renal colic visits." | 3.80 | Computerized physician order entry and decision support improves ED analgesic ordering for renal colic. ( Lang, E; Lonergan, K; McRae, A; Netherton, SJ; Wang, D, 2014) |
| "The pre-treatment pain severity of the groups was similar (p = 0." | 3.30 | The efficacy of intradermal sterile water application in severe renal colic: a randomised clinical trial. ( Ak, R; Aykanat, MC; Cimilli Öztürk, T; Kılıç, M; Ustaalioğlu, İ, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 4 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aykanat, MC | 1 |
| Kılıç, M | 1 |
| Cimilli Öztürk, T | 1 |
| Ustaalioğlu, İ | 1 |
| Ak, R | 1 |
| Nazemian, N | 1 |
| Torabi, M | 1 |
| Mirzaee, M | 1 |
| Rezaei, B | 1 |
| Salimi, R | 1 |
| Kalantari, A | 1 |
| Astaraki, P | 1 |
| Al, B | 1 |
| Sunar, MM | 1 |
| Zengin, S | 1 |
| Sabak, M | 1 |
| Bogan, M | 1 |
| Can, B | 1 |
| Kul, S | 1 |
| Murat Oktay, M | 1 |
| Eren, SH | 1 |
| Mozafari, J | 1 |
| Maleki Verki, M | 1 |
| Motamed, H | 1 |
| Sabouhi, A | 1 |
| Tirandaz, F | 1 |
| Netherton, SJ | 1 |
| Lonergan, K | 1 |
| Wang, D | 1 |
| McRae, A | 1 |
| Lang, E | 1 |
| Belkouch, A | 1 |
| Zidouh, S | 1 |
| Rafai, M | 1 |
| Chouaib, N | 1 |
| Sirbou, R | 1 |
| Elbouti, A | 1 |
| Bakkali, H | 1 |
| Belyamani, L | 1 |
| Imamoglu, M | 1 |
| Aygun, A | 1 |
| Bekar, O | 1 |
| Erdem, E | 1 |
| Cicek, M | 1 |
| Tatli, O | 1 |
| Karaca, Y | 1 |
| Sahin, A | 1 |
| Turkmen, S | 1 |
| Turedi, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Trial of Intranasal Fentanyl Versus Placebo as an Adjunct to Lidocaine Infiltration in Adults Undergoing Abscess Incision and Drainage in the Emergency[NCT03872700] | Phase 3 | 49 participants (Actual) | Interventional | 2019-08-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Patient reported NRS pain scores after Blunt Dissection. The NRS for pain is a reliable and validated measure of pain intensity ranging from 0 - no pain, to 10 - worst pain imaginable. (NCT03872700)
Timeframe: Measured once anytime up to 60 minutes following intranasal administration
| Intervention | score on a scale (Mean) |
|---|---|
| Intranasal Fentanyl | 4.1 |
| Placebo | 4.4 |
Patient reported NRS pain scores after Irrigation. The NRS for pain is a reliable and validated measure of pain intensity ranging from 0 - no pain, to 10 - worst pain imaginable. (NCT03872700)
Timeframe: Measured once anytime up to 60 minutes following intranasal administration
| Intervention | score on a scale (Mean) |
|---|---|
| Intranasal Fentanyl | 3.4 |
| Placebo | 2.6 |
Patient reported NRS pain scores after Lidocaine injection. The NRS for pain is a reliable and validated measure of pain intensity ranging from 0 - no pain, to 10 - worst pain imaginable. (NCT03872700)
Timeframe: Following Lidocaine injection measured once anytime up to 12 minutes after intranasal administration
| Intervention | score on a scale (Mean) |
|---|---|
| Intranasal Fentanyl | 8.4 |
| Placebo | 8.0 |
Patient reported pain after Packing of abscess. The NRS for pain is a reliable and validated measure of pain intensity ranging from 0 - no pain, to 10 - worst pain imaginable. (NCT03872700)
Timeframe: Measured once at the time of completion of application of the bandage, up to 60 minutes following intranasal administration
| Intervention | score on a scale (Mean) |
|---|---|
| Intranasal Fentanyl | 4.5 |
| Placebo | 3.9 |
Patient reported NRS pain scores following Incision. The NRS for pain is a reliable and validated measure of pain intensity ranging from 0 - no pain, to 10 - worst pain imaginable. (NCT03872700)
Timeframe: Measured once anytime up to 60 minutes following intranasal administration
| Intervention | score on a scale (Mean) |
|---|---|
| Intranasal Fentanyl | 3.9 |
| Placebo | 3.9 |
Patient reported pain scores at baseline. The NRS for pain is a reliable and validated measure of pain intensity ranging from 0 - no pain, to 10 - worst pain imaginable. (NCT03872700)
Timeframe: Baseline
| Intervention | score on a scale (Mean) |
|---|---|
| Intranasal Fentanyl | 8.3 |
| Placebo | 8.1 |
Patient reported pain scores for overall Procedure assessed immediately after placement of dressing at the end of procedure. The NRS for pain is a reliable and validated measure of pain intensity ranging from 0 - no pain, to 10 - worst pain imaginable. (NCT03872700)
Timeframe: Measured once following placement of dressing at completion of procedure, up to 60 minutes following intranasal administration
| Intervention | score on a scale (Mean) |
|---|---|
| Intranasal Fentanyl | 6.2 |
| Placebo | 7.0 |
4 trials available for fentanyl and Renal Colic
| Article | Year |
|---|---|
The efficacy of intradermal sterile water application in severe renal colic: a randomised clinical trial.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Fentanyl; Humans; Injectio | 2023 |
Atomized intranasal vs intravenous fentanyl in severe renal colic pain management: A randomized single-blinded clinical trial.
Topics: Administration, Intranasal; Administration, Intravenous; Adult; Aerosols; Aged; Anesthetics, Intrave | 2020 |
Comparison of IV dexketoprofen trometamol, fentanyl, and paracetamol in the treatment of renal colic in the ED: A randomized controlled trial.
Topics: Acetaminophen; Administration, Intravenous; Adolescent; Adult; Aged; Analgesics; Anti-Inflammatory A | 2018 |
Comparing intranasal ketamine with intravenous fentanyl in reducing pain in patients with renal colic: A double-blind randomized clinical trial.
Topics: Administration, Intranasal; Adult; Anesthetics, Dissociative; Anesthetics, Intravenous; Double-Blind | 2020 |
4 other studies available for fentanyl and Renal Colic
| Article | Year |
|---|---|
Comparison of efficacy nebulized fentanyl with intravenous ketorolac for renal colic in patients over 12 years old.
Topics: Acute Disease; Administration, Inhalation; Administration, Intravenous; Adolescent; Adult; Aged; Ana | 2021 |
Computerized physician order entry and decision support improves ED analgesic ordering for renal colic.
Topics: Adult; Analgesics; Decision Support Systems, Clinical; Emergency Service, Hospital; Female; Fentanyl | 2014 |
Does intranasal fentanyl provide efficient analgesia for renal colic in adults?
Topics: Administration, Intranasal; Adult; Aged; Analgesics, Opioid; Dose-Response Relationship, Drug; Emerg | 2015 |
A retrospective analysis of nebulized versus intravenous fentanyl for renal colic.
Topics: Administration, Inhalation; Administration, Intravenous; Adult; Analgesics, Opioid; Double-Blind Met | 2017 |