Page last updated: 2024-10-27

fentanyl and Pheochromocytoma

fentanyl has been researched along with Pheochromocytoma in 27 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Pheochromocytoma: A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)

Research Excerpts

ExcerptRelevanceReference
"In three patients undergoing pheochromocytoma resection under propofol/fentanyl anesthesia, bispectral index (BIS) was monitored for assessment of hypnotic effect."7.72[Anesthetic management with propofol during pheochromocytoma resection under bispectral index monitoring]. ( Ishida, K; Morimoto, Y; Nakamura, M; Sakabe, T; Utada, K; Yamashita, S, 2004)
" Anesthesia was induced with propofol and vecuronium, and maintained with intermittent fentanyl and sevoflurane in nitrous oxide and oxygen."3.72[Anesthetic management for removal of pheochromocytoma in a patient after repair of tetralogy of Fallot]. ( Hamakawa, T; Kawano, T; Maruta, T; Suzuki, N; Takasaki, M; Yano, T, 2004)
"In three patients undergoing pheochromocytoma resection under propofol/fentanyl anesthesia, bispectral index (BIS) was monitored for assessment of hypnotic effect."3.72[Anesthetic management with propofol during pheochromocytoma resection under bispectral index monitoring]. ( Ishida, K; Morimoto, Y; Nakamura, M; Sakabe, T; Utada, K; Yamashita, S, 2004)
"We have examined how fentanyl modulates [3H]noradrenaline uptake in two cultured neuronal cell preparations, the human neuroblastoma SH-SY5Y and the rat phaeochromocytoma PC12."3.68Fentanyl inhibits the uptake of [3H]noradrenaline in cultured neuronal cells. ( Atcheson, R; Lambert, DG; Rowbotham, DJ, 1993)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199015 (55.56)18.7374
1990's6 (22.22)18.2507
2000's4 (14.81)29.6817
2010's1 (3.70)24.3611
2020's1 (3.70)2.80

Authors

AuthorsStudies
Cunningham, E1
Kennedy, A1
Gregg, S1
O'Halloran, DJ1
Lowney, A1
Dortzbach, K1
Gainsburg, DM1
Frost, EA1
Shafiq, B1
Zuckerman, RL1
Queale, WS1
Cosgarea, AJ1
Yano, T1
Maruta, T1
Kawano, T1
Hamakawa, T1
Suzuki, N1
Takasaki, M1
Utada, K1
Ishida, K1
Nakamura, M1
Morimoto, Y1
Yamashita, S1
Sakabe, T1
Katagai, H1
Aoyagi, N1
Ishihara, H1
Kudo, M1
Matsuki, A1
Oyama, T1
Schwechheimer, K1
Mattfeldt, T1
Masuda, K1
Kawabata, M1
Itoh, T1
Atcheson, R1
Rowbotham, DJ1
Lambert, DG1
Schüttler, J1
Westhofen, P1
Kania, U1
Ihmsen, H1
Kammerecker, S1
Hirner, A1
Sakuragi, T1
Okamoto, I1
Fujiki, T1
Dan, K1
Sahin, A1
Erçelen, O1
Aypar, U1
Erbengi, A1
Matsota, P1
Avgerinopoulou-Vlahou, A1
Velegrakis, D1
Bittar, DA1
Stamenković, L1
Spierdijk, J1
Tjeuw, M1
Fong, J1
Strebel, S1
Scheidegger, D1
Brown, P1
Caplan, RA1
Barancik, M1
Shapiro, JD1
el-Ganzouri, A1
White, PF1
Ivankovich, AD1
Arai, T1
Hatano, Y1
Ishida, H1
Mori, K1
Lee, MK1
Braude, BM1
Leiman, BC1
Moyes, DG1
Zeller, K1
Clarke, AD1
Tobias, MA1
Challen, PD1
Simone, M1
Barusco, G1
Coan, B1
Kaniak, J1
Kuczyńska-Sekieta, K1
Skóra, K1
Suchnicki, Z1
Zagrobelny, Z1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of Stress Hormone Concentration During the Resection of Pheochromocytoma. Comparison of Surgeon - Anesthesiologist - Patient[NCT00948181]8 participants (Anticipated)Observational2009-06-30Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for fentanyl and Pheochromocytoma

ArticleYear
Palliative Symptom Management in Malignant Pheochromocytoma: Safe Use of Fentanyl and a Review of Medications Used.
    Journal of palliative medicine, 2023, Volume: 26, Issue:6

    Topics: Abdominal Pain; Adrenal Gland Neoplasms; Analgesics, Opioid; Female; Fentanyl; Humans; Middle Aged;

2023
Variants of pheochromocytoma and their anesthetic implications--a case report and literature review.
    Middle East journal of anaesthesiology, 2010, Volume: 20, Issue:6

    Topics: Adrenal Gland Neoplasms; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Car

2010

Trials

1 trial available for fentanyl and Pheochromocytoma

ArticleYear
[Quantitative assessment of catecholamine secretion as a rational principle of anesthesia management in pheochromocytoma surgery].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 1995, Volume: 30, Issue:6

    Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Alfentanil; Anesthesia, General; Anesthesia, Intravenous

1995

Other Studies

24 other studies available for fentanyl and Pheochromocytoma

ArticleYear
Hypertensive crisis secondary to pheochromocytoma during routine knee surgery.
    The journal of knee surgery, 2004, Volume: 17, Issue:3

    Topics: Adrenal Gland Neoplasms; Adult; Anesthetics, Intravenous; Arthroscopy; Fentanyl; Humans; Hypertensio

2004
[Anesthetic management for removal of pheochromocytoma in a patient after repair of tetralogy of Fallot].
    Masui. The Japanese journal of anesthesiology, 2004, Volume: 53, Issue:11

    Topics: Adrenal Gland Neoplasms; Anesthesia; Female; Fentanyl; Humans; Magnesium Sulfate; Methyl Ethers; Mid

2004
[Anesthetic management with propofol during pheochromocytoma resection under bispectral index monitoring].
    Masui. The Japanese journal of anesthesiology, 2004, Volume: 53, Issue:12

    Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Ch

2004
[Fentanyl anesthesia for the removal of pheochromocytoma].
    Masui. The Japanese journal of anesthesiology, 1984, Volume: 33, Issue:10

    Topics: Adrenal Gland Neoplasms; Adult; Anesthesia; Blood Pressure; Body Temperature; Catecholamines; Female

1984
[Fatal incident following administration of thalamonal in latent pheochromocytoma].
    Der Pathologe, 1983, Volume: 4, Issue:5

    Topics: Adrenal Gland Neoplasms; Adult; Anesthetics; Cerebral Infarction; Droperidol; Drug Combinations; Fem

1983
[High dose fentanyl anesthesia with nitroglycerin for the management of pheochromocytoma].
    Masui. The Japanese journal of anesthesiology, 1982, Volume: 31, Issue:12

    Topics: Adrenal Gland Neoplasms; Adult; Anesthesia; Fentanyl; Humans; Injections, Intravenous; Male; Nitrogl

1982
Fentanyl inhibits the uptake of [3H]noradrenaline in cultured neuronal cells.
    British journal of anaesthesia, 1993, Volume: 71, Issue:4

    Topics: Adrenal Gland Neoplasms; Animals; Dose-Response Relationship, Drug; Fentanyl; Humans; Imipramine; Mo

1993
Skin blood flow and plasma catecholamines during removal of pheochromocytoma.
    Anesthesiology, 1996, Volume: 85, Issue:6

    Topics: Adrenal Gland Neoplasms; Adult; Anesthetics, Intravenous; Epinephrine; Female; Fentanyl; Humans; Las

1996
Cerebral aneurysm surgery in a patient with phaeochromocytoma.
    European journal of anaesthesiology, 1998, Volume: 15, Issue:3

    Topics: Adrenal Gland Neoplasms; Anesthetics, Inhalation; Anesthetics, Intravenous; Antihypertensive Agents;

1998
Anaesthesia for phaeochromocytoma removal in a 5-year-old boy.
    Paediatric anaesthesia, 2002, Volume: 12, Issue:2

    Topics: Adjuvants, Anesthesia; Adrenal Gland Neoplasms; Anesthesia, General; Anesthetics, Inhalation; Anesth

2002
Innovar-induced hypertensive crises in patients with pheochromocytoma.
    Anesthesiology, 1979, Volume: 50, Issue:4

    Topics: Adrenal Gland Neoplasms; Droperidol; Drug Combinations; Fentanyl; Humans; Hypertension; Male; Middle

1979
Anaesthesia in patients with phaeochromocytoma.
    Anaesthesia, 1976, Volume: 31, Issue:7

    Topics: Anesthesia, General; Blood Pressure; Droperidol; Fentanyl; Humans; Neuroleptanalgesia; Nitroprusside

1976
Anaesthetic management of a patient with a single ventricle and phaeochromocytoma.
    Anaesthesia and intensive care, 1990, Volume: 18, Issue:4

    Topics: Adrenal Gland Neoplasms; Anesthesia, Intravenous; Blood Pressure; Central Venous Pressure; Child; Di

1990
Propofol-fentanyl anesthesia for pheochromocytoma resection.
    Acta anaesthesiologica Scandinavica, 1991, Volume: 35, Issue:3

    Topics: Adrenal Gland Neoplasms; Anesthesia, Intravenous; Female; Fentanyl; Humans; Middle Aged; Pheochromoc

1991
Recognition of an unsuspected phaeochromocytoma during elective coronary artery bypass surgery.
    Canadian Anaesthetists' Society journal, 1986, Volume: 33, Issue:6

    Topics: Adrenal Gland Neoplasms; Adrenergic beta-Antagonists; Aged; Catecholamines; Coronary Artery Bypass;

1986
Inadvertent diagnosis of pheochromocytoma after endoscopic premedication.
    Digestive diseases and sciences, 1989, Volume: 34, Issue:1

    Topics: Adrenal Gland Neoplasms; Aged; Female; Fentanyl; Gastroscopy; Humans; Hypertension; Pheochromocytoma

1989
Midazolam-sufentanil anaesthesia for phaeochromocytoma resection.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1988, Volume: 35, Issue:2

    Topics: Adrenal Gland Neoplasms; Aged; Anesthesia, Intravenous; Anesthetics; Female; Fentanyl; Humans; Midaz

1988
Use of nicardipine in the anesthetic management of pheochromocytoma.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:6

    Topics: Adult; Anesthesia, Local; Blood Pressure; Cardiac Output; Epinephrine; Female; Fentanyl; Heart Rate;

1986
Anaesthetic management for the removal of phaeochromocytoma with neuroleptanaesthesia using high dose fentanyl: a case report.
    Singapore medical journal, 1986, Volume: 27, Issue:2

    Topics: Adrenal Gland Neoplasms; Adult; Anesthesia, General; Droperidol; Female; Fentanyl; Humans; Neurolept

1986
Etomidate infusion for resection of phaeochromocytoma. A report of 2 cases.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1986, Jan-04, Volume: 69, Issue:1

    Topics: Adult; Anesthesia, Intravenous; Droperidol; Etomidate; Female; Fentanyl; Humans; Infusions, Parenter

1986
[Anesthesia in chronic patients].
    Bibliotheca tuberculosea, 1969, Volume: 25

    Topics: Adult; Aged; Anesthesia; Anesthetics; Anti-Bacterial Agents; Asthma; Benperidol; Chronic Disease; Fe

1969
The use of neuroleptanalgesia during surgery for phaeochromocytoma. Reports of two cases.
    British journal of anaesthesia, 1972, Volume: 44, Issue:10

    Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Benperidol; Blood Pressure; Central Venous Pressure; Ele

1972
[The use of NLA, type II, in the surgical treatment of pheochromocytoma].
    Acta anaesthesiologica, 1968, Volume: 19

    Topics: Adrenalectomy; Anesthesia; Benperidol; Female; Fentanyl; Humans; Hypertension; Hypotension; Male; Mi

1968
[A case of pheochromocytoma operated on in emergency under neuroleptoanalgesia type II (NLA II)].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1969, Apr-21, Volume: 24, Issue:15

    Topics: Adrenal Gland Neoplasms; Adult; Benperidol; Female; Fentanyl; Humans; Neuroleptanalgesia; Pheochromo

1969