Page last updated: 2024-10-27

fentanyl and Pain, Intractable

fentanyl has been researched along with Pain, Intractable in 100 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Pain, Intractable: Persistent pain that is refractory to some or all forms of treatment.

Research Excerpts

ExcerptRelevanceReference
" Our aim was to examine whether, fentanyl as well as morphine, two potent analgesic opioids commonly used to treat cancer pain, would inhibit pain and bone lesion-related responses in a murine model of bone cancer pain."7.74The impact of the opioids fentanyl and morphine on nociception and bone destruction in a murine model of bone cancer pain. ( El Mouedden, M; Meert, TF, 2007)
" Data from patients with noncancer or cancer pain treated with TD buprenorphine or TD fentanyl for at least 3 months between May 2002 and April 2005 were analyzed."7.73Patterns of dosage changes with transdermal buprenorphine and transdermal fentanyl for the treatment of noncancer and cancer pain: a retrospective data analysis in Germany. ( Nuijten, M; Poulsen Nautrup, B; Sittl, R, 2006)
"The purpose of this trial was to evaluate the effect of long-term treatment with oral sustained-release hydromorphone, transdermal fentanyl, and transdermal buprenorphine on nausea, emesis and constipation."5.14Gastrointestinal symptoms under opioid therapy: a prospective comparison of oral sustained-release hydromorphone, transdermal fentanyl, and transdermal buprenorphine. ( Kloecker, N; Mueller, M; Nadstawek, J; Schaefer, N; Schenk, M; Schroeck, A; Standop, J; Wirz, S; Wittmann, M, 2009)
"A new method of administration of an opioid was recently registered: fentanyl transdermal (brand name: Durogesic), intended particularly for the indication range 'pain in cancer'."4.79[Transdermal opioid administration: the pain plaster]. ( Sillevis Smitt, PA; Vecht, CJ, 1997)
"We report a case of serotonin syndrome caused by interaction between nasal fentanyl, oxycodone and escitalopram."3.76[Serotoninergic antidepressants and opiate analgesics: a sometimes-painful association. A case report]. ( Lefebvre-Kuntz, D; Reich, M, 2010)
" Our aim was to examine whether, fentanyl as well as morphine, two potent analgesic opioids commonly used to treat cancer pain, would inhibit pain and bone lesion-related responses in a murine model of bone cancer pain."3.74The impact of the opioids fentanyl and morphine on nociception and bone destruction in a murine model of bone cancer pain. ( El Mouedden, M; Meert, TF, 2007)
" Data from patients with noncancer or cancer pain treated with TD buprenorphine or TD fentanyl for at least 3 months between May 2002 and April 2005 were analyzed."3.73Patterns of dosage changes with transdermal buprenorphine and transdermal fentanyl for the treatment of noncancer and cancer pain: a retrospective data analysis in Germany. ( Nuijten, M; Poulsen Nautrup, B; Sittl, R, 2006)
" The Cmax and AUC0-72 tended to increase with dosage from 2."2.79Pharmacokinetics of a new fentanyl tape with a novel delivery system of transdermal matrix patches in patients with cancer pain. ( Fujii, M; Fujiwara, K; Kobayashi, K; Saito, S; Saito, T; Shimada, K, 2014)
"In patients with moderate to severe cancer pain receiving treatment with opioid analgesics, the treatment was switched from the existing opioid analgesic to the 1-day fentanyl patch (the "1-day formulation"), and the efficacy and safety of the 1-day formulation were evaluated."2.76[Clinical study of one-day fentanyl patch in patients with cancer pain--evaluation of the efficacy and safety in relation to treatment switch from opioid analgesic therapy]. ( Hanaoka, K; Sakata, H; Tomioka, T; Yoshimura, T, 2011)
"Dose titration of the 1-day formulation was accomplished in a short period in patients with cancer pain who had been previously untreated with opioid analgesics; the efficacy of the formulation for pain control after repeated dosing was comparable to that of the 3-day formulation, and its tolerability was good."2.76[Double-blind parallel-group dose-titration study comparing a fentanyl-containing patch formulated for 1-day application for the treatment of cancer pain with Durotep MT Patch]. ( Hanaoka, K; Sakata, H; Tomioka, T; Yoshimura, T, 2011)
"Oral morphine was used as breakthrough pain medication during opioid titration."2.73Sustained-release oral morphine versus transdermal fentanyl and oral methadone in cancer pain management. ( Aielli, F; Casuccio, A; Ferrera, P; Ficorella, C; Fulfaro, F; Gebbia, V; Mangione, S; Mercadante, S; Porzio, G; Riina, S; Verna, L; Villari, P, 2008)
"Patients with cancer often are rotated from other opioids to methadone to improve the balance between analgesia and side effects."2.71Opioid switching from transdermal fentanyl to oral methadone in patients with cancer pain. ( Benítez-Rosario, MA; Feria, M; Martín-Ortega, JJ; Martínez-Castillo, LP; Salinas-Martín, A, 2004)
"Sixty-six patients with cancer-related pain entered an open multicentre study to examine the safety and efficacy of oral transmucosal fentanyl citrate (OTFC) in the treatment of breakthrough pain."2.71Oral transmucosal fentanyl citrate in the management of breakthrough pain in cancer: an open, multicentre, dose-titration and long-term use study. ( Busch, MA; Hanks, GW; Higgs, CM; Nugent, M, 2004)
" Safety was assessed by recording the advent of adverse events and efficacy by the evaluating the intensity of breakthrough pain."2.71[Safety and efficacy of oral trans-mucosal fentanyl citrate in the long-term treatment of breakthrough pain in oncology patients: the ECODIR study]. ( Camps Herrero, C; Carulla Torrent, J; Cassinello Espinosa, J; Dorta Delgado, J; Jara Sánchez, C; Moreno Nogueira, JA; Valentín Maganto, V, 2005)
" Transdermal fentanyl dosage was titrated upwards as required."2.70Opioids in non-cancer pain: a life-time sentence? ( Dellemijn, PL, 2001)
" (2) To estimate the pediatric pharmacokinetic parameters of TTS-fentanyl."2.69Transdermal fentanyl in children with cancer pain: feasibility, tolerability, and pharmacokinetic correlates. ( Collins, JJ; Dunkel, IJ; Gupta, SK; Inturrisi, CE; Lapin, J; Palmer, LN; Portenoy, RK; Weinstein, SM, 1999)
"Initial dose finding in patients with cancer pain who are started on TTS fentanyl (Duragesic, TTS-F) is often unsatisfactory with currently recommended doses and intervals."2.68Day-to-day titration to initiate transdermal fentanyl in patients with cancer pain: short- and long-term experiences in a prospective study of 39 patients. ( de Stoutz, N; Korte, W; Morant, R, 1996)
"Forty of 47 cancer patients completed the study with 20 patients in each group."2.68Comparison of oral controlled-release morphine with transdermal fentanyl in terminal cancer pain. ( Chang, CL; Chiu, GL; Tsao, CJ; Wong, JO, 1997)
"Use of prescription opioids for cancer pain according to the World Health Organization analgesic ladder has been accepted in Japan."2.52[Interindividual variation of pharmacokinetic disposition of and clinical responses to opioid analgesics in cancer pain patients]. ( Kawakami, J; Naito, T, 2015)
"Fentanyl sublingual was generally well tolerated in the two trials and most adverse events were mild to moderate in intensity."2.46Fentanyl sublingual: in breakthrough pain in opioid-tolerant adults with cancer. ( Chwieduk, CM; McKeage, K, 2010)
" Long-acting oral opioids supply satisfactory analgesia at more convenient dosing intervals."2.43Advances in opioid therapy and formulations. ( Walsh, D, 2005)
"Breakthrough pain in patients with cancer is a common problem with characteristics that make it difficult to treat."2.43Oral transmucosal fentanyl citrate for cancer breakthrough pain: a review. ( Gordon, DB, 2006)
"Patients with moderate to severe malignancy-related pain frequently require the use of opioid pharmacotherapy."2.43Transdermal opioids for cancer pain. ( Skaer, TL, 2006)
" Latency is a much less important problem for chronic administration in cancer pain."2.39[Transcutaneous fentanyl]. ( Estève, M, 1994)
"The use of TDF for the treatment of cancer pain is not associated with impairment in cognitive performance."1.40[The cognitive effects of using transdermal fentanyl in cancer pain]. ( Ali, A; Bilen, A; Turgut, N; Türkmen, A; Unlü, N, 2014)
"Demographic data, cancer type, duration of pain, side effects, visual analog scale (VAS) score, treatment assessment scale (TAS) score, TDF dosage, and the number of patients in whom therapy has been terminated were recorded."1.38[Comparison of transdermal fentanyl for the management of cancer pain in adults and elders]. ( Ali, A; Alkan, I; Altan, A; Bilen, A, 2012)
" 33 patients in terminal stage of carcinoma, who had been treated by transdermal fentanyl due to their excruciating pain (7-10 mark on numerical scale) with initial dosage of 25 microg as a strong opiate analgesic, were monitored within the time period of 10 days."1.36Treatment of severe cancer pain by transdermal fentanyl. ( Husić, S; Ljuca, D, 2010)
"The fentanyl patch was equally divided by drawing a line on the side on which the product name and dose were written."1.35[Evaluation of the 2.5 mg fentanyl patch, applied using the half-side application procedure in patients with cancer pain]. ( Hoka, S; Kokubun, H; Matoba, M; Okazaki, M; Yago, K, 2008)
"Fentanyl has been used for cancer pain in transdermal formulation."1.35Validated LC coupled to ESI-MS/MS analysis for fentanyl in human plasma and UV analysis in applied reservoir transdermal patches using a simple and rapid procedure. ( Kagawa, Y; Kawakami, J; Mino, Y; Naito, T; Takashina, Y, 2009)
" Six patients receiving TTS BU were switched to TTS FE and then rotated back to TTS BU with the same dosing considerations."1.34Switching from transdermal drugs: an observational "N of 1" study of fentanyl and buprenorphine. ( Aielli, F; Casuccio, A; Ficorella, C; Fulfaro, F; Intravaia, G; Mangione, S; Mercadante, S; Porzio, G; Riina, S; Verna, L, 2007)
"Basing on the components and the endurable dosage of each component for children, we formulated the appropriate dosage and usage of a few analgesics (including sustained release tablets of morphine, oxycodone and transdermal fantanyl) available in China, most of which were used in adults."1.34[Feasibility to treat pediatric cancer pain with analgesics for adults and their efficacy]. ( Lin, H; Ling, JY; Luo, WB; Sun, XF; Xia, Y; Zhen, ZJ; Zheng, L, 2007)
"The fentanyl patch is a useful agent to control severe cancer pain because of excellent analgesic effect, less adverse effects and more convenience as well as itsundesirable characteristics when transition of patients to home-care is considered or oral administration should be avoided."1.34[Usefulness of fentanyl patch (Durotep) in cancer patients when rotated from morphine preparations]. ( Akiyama, Y; Iseki, M; Ishii, K; Izawa, R; Miyazaki, T; Tani, Y; Yamaguchi, S, 2007)
"Eighteen patients with cancer receiving transdermal fentanyl with uncontrolled pain and/or moderate to severe opioid adverse effects, were switched to oral methadone using an initial fixed ratio of 1:20."1.34Opioid plasma concentrations during a switch from transdermal fentanyl to methadone. ( Casuccio, A; Ferrera, P; Gambaro, V; Mercadante, S; Villari, P, 2007)
"The vast majority of patients with cancer pain are prescribed opioids in oral formulation."1.33[Parenteral opioids in end-of-life care in cancer patients]. ( Hattori, S; Kimura, N; Noguchi, T; Takatani, J, 2005)
"The mechanisms responsible for neuropathic pain are not fully understood."1.33[Transdermal fentanyl for neuropathic pain: a case report]. ( Kara, I; Otelcioğlu, S; Reisli, R; Tuncer, S, 2006)
"The efficacy and QOL in a cancer pain patient who converted to transdermal fentanyl from low-dose morphine (n=5) or high-dose morphine (n=5) were retrospectively compared."1.33[Direct conversion from low-dose morphine to transdermal fentanyl: efficacy for cancer pain and quality of life]. ( Akashi, T; Aoki, T; Tachibana, M; Yamazaki, M, 2006)
" During the long-term treatment, the transdermal fentanyl dosage had to be increased."1.32[Home palliative care--2 case reports: a long-term cancer pain management with transdermal fentanyl]. ( Fujimoto, M; Kuroda, T; Mizutani, Y; Sakuyama, T; Yanaga, K, 2004)
" No systemic adverse events were noted; two patients reported nasal itching or discomfort on first use that disappeared with repeated use."1.31An assessment of the safety, efficacy, and acceptability of intranasal fentanyl citrate in the management of cancer-related breakthrough pain: a pilot study. ( Zeppetella, G, 2000)
"1 mg/hour of methadone may be safe and effective."1.31Intravenous methadone in the management of chronic cancer pain: safe and effective starting doses when substituting methadone for fentanyl. ( Fischberg, DJ; Khojainova, N; Kornick, C; Manfredi, P; Payne, R; Primavera, LH; Santiago-Palma, J, 2001)
"Both morphine and fentanyl were used."1.30Nurse-controlled analgesia using a patient-controlled analgesia device: an alternative strategy in the management of severe cancer pain in children. ( Cooper, MG; Kanagasundaram, SA; Lane, LJ, 1997)
"Ten patients with advanced cancer and breakthrough pain between the ages of 39 and 78 received oral transmucosal fentanyl citrate (10-15 micrograms/kg) 4 or 5 times each over 2 days (42 total administrations) in an open study."1.28An open label study of oral transmucosal fentanyl citrate (OTFC) for the treatment of breakthrough cancer pain. ( De Boer, JA; Fine, PG; Marcus, M; Van der Oord, B, 1991)

Research

Studies (100)

TimeframeStudies, this research(%)All Research%
pre-19906 (6.00)18.7374
1990's20 (20.00)18.2507
2000's52 (52.00)29.6817
2010's22 (22.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bilen, A4
Ali, A4
Baturay, F2
Ozcan, B1
Altan, A3
Meissner, W1
Sabatowski, R1
Beutlhauser, T1
Oeltjenbruns, J1
Schäfer, M1
Ibuki, T1
Saito, T1
Fujii, M1
Saito, S1
Shimada, K1
Fujiwara, K1
Kobayashi, K1
Corli, O1
Roberto, A1
Ertaş, IE1
Sehirali, S1
Ozsezgin Ocek, S1
Sancı, M1
Arbak, G1
Yıldırım, Y1
Yoshitake, A1
Yamamoto, T1
Susaki, S1
Abe, E1
Unlü, N1
Turgut, N1
Türkmen, A1
Naito, T2
Kawakami, J2
Hayek, SM1
Sweet, JA1
Miller, JP1
Sayegh, RR1
Hair, PI1
Keating, GM1
McKeage, K2
Wirz, S1
Wittmann, M1
Schenk, M1
Schroeck, A1
Schaefer, N1
Mueller, M1
Standop, J1
Kloecker, N1
Nadstawek, J1
Goodman, SR1
Smiley, RM1
Negron, MA1
Freedman, PA1
Landau, R1
Einarson, A1
Bozzo, P1
Taguchi, N1
Matsui, T1
Kojima, T1
Kojima, H1
Iwamoto, N1
Kure, S1
Uemura, T1
Fujimitsu, Y1
Sakamoto, J1
Matsuyama, K1
Satomi, E1
Ueno, H1
Inoue, A1
Oike, M1
Todaka, K1
Yoshida, T1
Sekiyama, R1
Hirotsune, H1
Sueta, K1
Miyamoto, A1
Nakamori, S1
Tsujinaka, T1
Komori, K1
Takashina, Y1
Mino, Y1
Kagawa, Y1
Jacobsen, R1
Møldrup, C1
Christrup, L1
Ljuca, D1
Husić, S1
Reich, M1
Lefebvre-Kuntz, D1
Park, JH1
Kim, JH1
Yun, SC1
Roh, SW1
Rhim, SC1
Kim, CJ1
Jeon, SR1
Chwieduk, CM1
Hanaoka, K2
Yoshimura, T2
Tomioka, T2
Sakata, H2
Alkan, I1
Hisada, T1
Katoh, M1
Hitoshi, K1
Kondo, Y2
Fujioka, M1
Toyama, Y1
Ieda, H1
Gocho, S1
Nadai, M1
Enting, RH1
Oldenmenger, WH1
van der Rijt, CC1
Wilms, EB1
Elfrink, EJ1
Elswijk, I1
Sillevis Smitt, PA2
Chen, DY1
Lu, MS1
Tan, MY1
Carter, AC1
Nicholas, JJ1
Mystakidou, K1
Tsilika, E1
Parpa, E1
Kouloulias, V1
Kouvaris, I1
Georgaki, S1
Vlahos, L1
Tennant, F1
Hermann, L1
Yu, SY2
Sun, Y2
Zhang, HC2
Wu, YL2
Qin, SK2
Xie, GR2
Liu, SJ2
Sui, G1
Taha, J1
Favre, J1
Janszen, M1
Galarza, M1
Taha, A1
Yoshizawa, A1
Gyouda, Y1
Ishiguro, T1
Yoshizawa, T1
Yoshida, S1
Benítez-Rosario, MA1
Feria, M1
Salinas-Martín, A1
Martínez-Castillo, LP1
Martín-Ortega, JJ1
Walsh, D1
Hanks, GW2
Nugent, M1
Higgs, CM1
Busch, MA2
Fujimoto, M1
Sakuyama, T1
Mizutani, Y1
Kuroda, T1
Yanaga, K1
Hattori, S1
Kimura, N1
Takatani, J1
Noguchi, T1
Reid, C1
Bozkurt, P1
Bakan, M1
Kilinç, LT1
Oltmanns, KM1
Fehm, HL1
Peters, A1
Jung, BF1
Reidenberg, MM1
Valentín Maganto, V1
Camps Herrero, C1
Carulla Torrent, J1
Cassinello Espinosa, J1
Dorta Delgado, J1
Jara Sánchez, C1
Moreno Nogueira, JA1
Sui, GJ1
Shinjo, T1
Okada, M1
Finkel, JC1
Finley, A1
Greco, C1
Weisman, SJ1
Zeltzer, L1
Yamazaki, M1
Aoki, T1
Tachibana, M1
Akashi, T1
Gordon, DB1
Kamiya, N1
Yasogawa, Y1
Nishi, Y1
Takahashi, Y1
Hirai, T1
Sakurai, M1
Masumizu, K1
Onosato, W1
Koyama, T1
Skaer, TL1
Sittl, R1
Nuijten, M1
Poulsen Nautrup, B1
Akiyama, Y1
Iseki, M1
Izawa, R1
Ishii, K1
Miyazaki, T1
Yamaguchi, S1
Tani, Y1
Tuncer, S1
Reisli, R1
Kara, I1
Otelcioğlu, S1
Mercadante, S3
Villari, P2
Ferrera, P2
Casuccio, A3
Gambaro, V1
El Mouedden, M1
Meert, TF1
Hashizume, T1
Tomiyasu, S1
Yomiya, K1
Yoshimoto, T1
Harada, A1
Matoba, M2
Porzio, G2
Fulfaro, F2
Aielli, F2
Verna, L2
Ficorella, C2
Riina, S2
Intravaia, G1
Mangione, S2
Zhen, ZJ1
Sun, XF1
Xia, Y1
Ling, JY1
Zheng, L1
Luo, WB1
Lin, H1
Kokubun, H1
Okazaki, M1
Hoka, S1
Yago, K1
Gebbia, V1
Wright, RM1
Goroszeniuk, T1
Gourlay, GK1
Cousins, MJ1
Singler, RC1
Zenz, M1
Donner, B1
Strumpf, M1
Singer, M1
Noonan, KR1
Korte, W2
Estève, M1
de Stoutz, N1
Morant, R1
Leelanuntakit, S1
Fainsinger, RL1
Bruera, E2
Grond, S1
Zech, D1
Lehmann, KA1
Radbruch, L1
Breitenbach, H1
Hertel, D1
Wong, JO1
Chiu, GL1
Tsao, CJ1
Chang, CL1
Vecht, CJ1
Kanagasundaram, SA1
Cooper, MG1
Lane, LJ1
Gordon, RL1
Watanabe, S1
Pereira, J1
Hanson, J1
Collins, JJ1
Dunkel, IJ1
Gupta, SK1
Inturrisi, CE1
Lapin, J1
Palmer, LN1
Weinstein, SM1
Portenoy, RK3
Payne, R2
Coluzzi, P1
Raschko, JW1
Lyss, A1
Frigerio, V1
Ingham, J1
Loseth, DB1
Nordbrock, E1
Rhiner, M1
Pasero, C1
McCaffery, M1
Chiang, JS1
Zeppetella, G1
Farrar, JT1
Berlin, JA1
Kinman, JL1
Strom, BL1
Bleeker, CP1
Bremer, RC1
Dongelmans, DA1
van Dongen, RT1
Crul, BJ1
Dellemijn, PL1
Santiago-Palma, J1
Khojainova, N1
Kornick, C1
Fischberg, DJ1
Primavera, LH1
Manfredi, P1
Rodos, JJ1
Burton, A1
Kalso, E1
Hassenbusch, SJ1
Stanton-Hicks, MD1
Soukup, J1
Covington, EC1
Boland, MB1
Fine, PG2
Marcus, M1
De Boer, JA1
Van der Oord, B1
Ashburn, MA1
Stanley, TH1
Ehring, E1
Boekstegers, A1
Tasker, RR1
Organ, LW1
Smith, KC1

Clinical Trials (8)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Double-blind, Randomized, Controlled, Pilot Study Comparing Three Different Anesthesic Techniques for Pregnant Women in Labour: Dural Puncture Epidural, Epidural and Combined Spinal Epidural. Evaluation of the Pain Control and the Hypotension Incidence [NCT05196256]Phase 390 participants (Anticipated)Interventional2022-06-30Not yet recruiting
A Randomized Double Blind Clinical Trial Comparing Programed Intermittent Epidural Boluses (PIEB) Versus Patient Controlled Epidural Analgesia (PCEA) With Epidural or Combined Spinal-epidural (CSE) Technique[NCT02768272]Phase 4240 participants (Actual)Interventional2016-03-01Completed
Evaluation in Efficacy and Safety of Fentanyl-TTS (Durogesic® D-Trans) for Treatment of Chronic Pain[NCT01902524]Phase 465 participants (Actual)Interventional2005-10-31Completed
A Study to Assess the Safety, Dose Conversion and Titration of DURAGESIC® (Fentanyl Transdermal System) in Pediatric Subjects With Chronic Pain Requiring Opioid Therapy[NCT00271466]Phase 3199 participants (Actual)Interventional2000-02-29Completed
Exploratory Study on the Use of Pregabalin for the Treatment of Taxol Related Arthralgia-Myalgia[NCT02024568]Phase 238 participants (Anticipated)Interventional2013-12-31Not yet recruiting
Patients' Conscious Experience and Psychological Consequences of Awake Surgery for Intracerebral Lesions[NCT02622529]20 participants (Actual)Observational2015-11-30Completed
Evaluation of Pain Before and After Removal of Non-obstructive Kidney Stones[NCT03657667]43 participants (Actual)Interventional2018-08-28Completed
Randomized Double-blind Controlled Study to Assess the Efficacy of Intravenous Acetaminophen Associated With Strong Opioids in the Management of Acute Pain in Adult Cancer Patients[NCT04779567]Phase 4112 participants (Actual)Interventional2019-06-10Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

15 reviews available for fentanyl and Pain, Intractable

ArticleYear
[Breakthrough pain and short-acting opioids].
    Der Anaesthesist, 2013, Volume: 62, Issue:6

    Topics: Administration, Intranasal; Administration, Mucosal; Analgesics, Opioid; Breakthrough Pain; Delayed-

2013
Pharmacological and clinical differences among transmucosal fentanyl formulations for the treatment of breakthrough cancer pain: a review article.
    Minerva anestesiologica, 2014, Volume: 80, Issue:10

    Topics: Administration, Mucosal; Analgesics, Opioid; Chemistry, Pharmaceutical; Fentanyl; Humans; Neoplasms;

2014
[Interindividual variation of pharmacokinetic disposition of and clinical responses to opioid analgesics in cancer pain patients].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2015, Volume: 135, Issue:5

    Topics: Analgesics, Opioid; ATP Binding Cassette Transporter, Subfamily B; Cytochrome P-450 CYP2D6; Cytochro

2015
Transdermal matrix fentanyl membrane patch (matrifen): in severe cancer-related chronic pain.
    Drugs, 2008, Volume: 68, Issue:14

    Topics: Administration, Cutaneous; Analgesics, Opioid; Chronic Disease; Fentanyl; Humans; Neoplasms; Pain, I

2008
Fentanyl sublingual: in breakthrough pain in opioid-tolerant adults with cancer.
    Drugs, 2010, Dec-03, Volume: 70, Issue:17

    Topics: Administration, Sublingual; Adult; Analgesics, Opioid; Clinical Trials as Topic; Fentanyl; Humans; N

2010
Advances in opioid therapy and formulations.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2005, Volume: 13, Issue:3

    Topics: Administration, Cutaneous; Analgesia, Patient-Controlled; Analgesics, Opioid; Chemistry, Pharmaceuti

2005
Contribution to variability in response to opioids.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2005, Volume: 13, Issue:3

    Topics: Analgesics, Opioid; Biological Availability; Dose-Response Relationship, Drug; Drug Administration S

2005
Interpretation of opioid levels: comparison of levels during chronic pain therapy to levels from forensic autopsies.
    Clinical pharmacology and therapeutics, 2005, Volume: 77, Issue:4

    Topics: Analgesics, Opioid; Autopsy; Fentanyl; Humans; Methadone; Morphine; Oxycodone; Pain, Intractable

2005
Oral transmucosal fentanyl citrate for cancer breakthrough pain: a review.
    Oncology nursing forum, 2006, Nov-03, Volume: 33, Issue:2

    Topics: Administration, Buccal; Administration, Oral; Administration, Sublingual; Analgesics, Opioid; Dose-R

2006
Transdermal opioids for cancer pain.
    Health and quality of life outcomes, 2006, Mar-31, Volume: 4

    Topics: Administration, Cutaneous; Administration, Oral; Algorithms; Analgesics, Opioid; Buprenorphine; Dose

2006
[Transcutaneous fentanyl].
    Cahiers d'anesthesiologie, 1994, Volume: 42, Issue:2

    Topics: Administration, Cutaneous; Chronic Disease; Fentanyl; Humans; Pain, Intractable; Pain, Postoperative

1994
How should we use transdermal fentanyl (TF) for pain management in palliative care patients?
    Journal of palliative care, 1996,Spring, Volume: 12, Issue:1

    Topics: Administration, Cutaneous; Aged; Analgesics, Opioid; Canada; Child; Female; Fentanyl; Humans; Male;

1996
[Transdermal opioid administration: the pain plaster].
    Nederlands tijdschrift voor geneeskunde, 1997, Apr-26, Volume: 141, Issue:17

    Topics: Administration, Cutaneous; Analgesics, Opioid; Fentanyl; Humans; Morphine; Pain; Pain, Intractable

1997
New developments in cancer pain therapy.
    Acta anaesthesiologica Sinica, 2000, Volume: 38, Issue:1

    Topics: Adrenal Medulla; Adrenergic alpha-Agonists; Analgesics, Opioid; Cell Transplantation; Cyclooxygenase

2000
[New opioid preparations in the treatment of pain].
    Duodecim; laaketieteellinen aikakauskirja, 1999, Volume: 115, Issue:20

    Topics: Administration, Cutaneous; Analgesics, Opioid; Clinical Competence; Fentanyl; Humans; Hydromorphone;

1999

Trials

25 trials available for fentanyl and Pain, Intractable

ArticleYear
[Concomitant use of strong and weak opioids in the management of chronic cancer pain].
    Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology, 2013, Volume: 25, Issue:1

    Topics: Administration, Cutaneous; Analgesics, Opioid; Dose-Response Relationship, Drug; Drug Administration

2013
Pharmacokinetics of a new fentanyl tape with a novel delivery system of transdermal matrix patches in patients with cancer pain.
    Oncology, 2014, Volume: 86, Issue:1

    Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Analgesics, Opioid; Area Under Curve; Drug Deliv

2014
The effectiveness of subcutaneously implanted epidural ports for relief of severe pain in patients with advanced-stage gynecological cancer: a prospective study.
    Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology, 2014, Volume: 26, Issue:1

    Topics: Administration, Cutaneous; Aged; Analgesics, Opioid; Epidural Space; Female; Fentanyl; Genital Neopl

2014
Gastrointestinal symptoms under opioid therapy: a prospective comparison of oral sustained-release hydromorphone, transdermal fentanyl, and transdermal buprenorphine.
    European journal of pain (London, England), 2009, Volume: 13, Issue:7

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Antiemetics; Buprenor

2009
A randomized trial of breakthrough pain during combined spinal-epidural versus epidural labor analgesia in parous women.
    Anesthesia and analgesia, 2009, Volume: 108, Issue:1

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Anesthetics, Local; Bupivaca

2009
A randomized trial of breakthrough pain during combined spinal-epidural versus epidural labor analgesia in parous women.
    Anesthesia and analgesia, 2009, Volume: 108, Issue:1

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Anesthetics, Local; Bupivaca

2009
A randomized trial of breakthrough pain during combined spinal-epidural versus epidural labor analgesia in parous women.
    Anesthesia and analgesia, 2009, Volume: 108, Issue:1

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Anesthetics, Local; Bupivaca

2009
A randomized trial of breakthrough pain during combined spinal-epidural versus epidural labor analgesia in parous women.
    Anesthesia and analgesia, 2009, Volume: 108, Issue:1

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Anesthetics, Local; Bupivaca

2009
Evaluation of efficacy and safety of fentanyl transdermal patch (Durogesic D-TRANS) in chronic pain.
    Acta neurochirurgica, 2011, Volume: 153, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Chronic Disease; Female; Fentanyl; Humans; Male;

2011
[Breakthrough pain frequency in cancer patients and the efficiency of oral transmucosal fentanyl citrate].
    Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology, 2010, Volume: 22, Issue:3

    Topics: Administration, Cutaneous; Administration, Oral; Analgesics, Opioid; Fentanyl; Humans; Narcotics; Ne

2010
[Clinical study of one-day fentanyl patch in patients with cancer pain--evaluation of the efficacy and safety in relation to treatment switch from opioid analgesic therapy].
    Masui. The Japanese journal of anesthesiology, 2011, Volume: 60, Issue:2

    Topics: Administration, Cutaneous; Aged; Analgesics, Opioid; Dosage Forms; Female; Fentanyl; Humans; Male; M

2011
[Double-blind parallel-group dose-titration study comparing a fentanyl-containing patch formulated for 1-day application for the treatment of cancer pain with Durotep MT Patch].
    Masui. The Japanese journal of anesthesiology, 2011, Volume: 60, Issue:2

    Topics: Administration, Cutaneous; Aged; Analgesics, Opioid; Dosage Forms; Double-Blind Method; Female; Fent

2011
Self-treatment with oral transmucosal fentanyl citrate to prevent emergency room visits for pain crises: patient self-reports of efficacy and utility.
    Journal of pain & palliative care pharmacotherapy, 2002, Volume: 16, Issue:3

    Topics: Administration, Sublingual; Adult; Aged; Analgesics, Opioid; California; Chronic Disease; Emergency

2002
Opioid switching from transdermal fentanyl to oral methadone in patients with cancer pain.
    Cancer, 2004, Dec-15, Volume: 101, Issue:12

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Aged; Analgesics, Opioid; Drug Administratio

2004
Oral transmucosal fentanyl citrate in the management of breakthrough pain in cancer: an open, multicentre, dose-titration and long-term use study.
    Palliative medicine, 2004, Volume: 18, Issue:8

    Topics: Administration, Buccal; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Female; Fentanyl; Humans

2004
[Safety and efficacy of oral trans-mucosal fentanyl citrate in the long-term treatment of breakthrough pain in oncology patients: the ECODIR study].
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2005, Volume: 7, Issue:5

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Female; Fentanyl; Humans;

2005
Transdermal fentanyl in the management of children with chronic severe pain: results from an international study.
    Cancer, 2005, Dec-15, Volume: 104, Issue:12

    Topics: Administration, Cutaneous; Adolescent; Analgesics, Opioid; Child; Child, Preschool; Chronic Disease;

2005
Sustained-release oral morphine versus transdermal fentanyl and oral methadone in cancer pain management.
    European journal of pain (London, England), 2008, Volume: 12, Issue:8

    Topics: Administration, Cutaneous; Administration, Oral; Adolescent; Adult; Aged; Analgesia; Analgesics, Opi

2008
Day-to-day titration to initiate transdermal fentanyl in patients with cancer pain: short- and long-term experiences in a prospective study of 39 patients.
    Journal of pain and symptom management, 1996, Volume: 11, Issue:3

    Topics: Administration, Cutaneous; Adult; Aged; Analgesics, Opioid; Female; Fentanyl; Humans; Male; Middle A

1996
Management of cancer-related pain with transdermal fentanyl.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 1996, Volume: 79, Issue:6

    Topics: Administration, Cutaneous; Adult; Aged; Analgesics, Opioid; Dose-Response Relationship, Drug; Female

1996
Transdermal fentanyl in the long-term treatment of cancer pain: a prospective study of 50 patients with advanced cancer of the gastrointestinal tract or the head and neck region.
    Pain, 1997, Volume: 69, Issue:1-2

    Topics: Administration, Cutaneous; Analgesics, Opioid; Female; Fentanyl; Gastrointestinal Neoplasms; Head an

1997
Comparison of oral controlled-release morphine with transdermal fentanyl in terminal cancer pain.
    Acta anaesthesiologica Sinica, 1997, Volume: 35, Issue:1

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Aged; Analgesics, Opioid; Female; Fentanyl;

1997
Fentanyl by continuous subcutaneous infusion for the management of cancer pain: a retrospective study.
    Journal of pain and symptom management, 1998, Volume: 16, Issue:5

    Topics: Aged; Analgesics, Opioid; Female; Fentanyl; Humans; Injections, Subcutaneous; Male; Neoplasms; Pain,

1998
Transdermal fentanyl in children with cancer pain: feasibility, tolerability, and pharmacokinetic correlates.
    The Journal of pediatrics, 1999, Volume: 134, Issue:3

    Topics: Administration, Cutaneous; Adolescent; Analgesics, Opioid; Child; Feasibility Studies; Fentanyl; Hum

1999
Oral transmucosal fentanyl citrate (OTFC) for the treatment of breakthrough pain in cancer patients: a controlled dose titration study.
    Pain, 1999, Volume: 79, Issue:2-3

    Topics: Administration, Oral; Adult; Aged; Analgesics, Opioid; Dose-Response Relationship, Drug; Double-Blin

1999
Defining the clinically important difference in pain outcome measures.
    Pain, 2000, Dec-01, Volume: 88, Issue:3

    Topics: Analgesics, Opioid; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Confidenc

2000
Defining the clinically important difference in pain outcome measures.
    Pain, 2000, Dec-01, Volume: 88, Issue:3

    Topics: Analgesics, Opioid; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Confidenc

2000
Defining the clinically important difference in pain outcome measures.
    Pain, 2000, Dec-01, Volume: 88, Issue:3

    Topics: Analgesics, Opioid; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Confidenc

2000
Defining the clinically important difference in pain outcome measures.
    Pain, 2000, Dec-01, Volume: 88, Issue:3

    Topics: Analgesics, Opioid; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Confidenc

2000
Defining the clinically important difference in pain outcome measures.
    Pain, 2000, Dec-01, Volume: 88, Issue:3

    Topics: Analgesics, Opioid; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Confidenc

2000
Defining the clinically important difference in pain outcome measures.
    Pain, 2000, Dec-01, Volume: 88, Issue:3

    Topics: Analgesics, Opioid; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Confidenc

2000
Defining the clinically important difference in pain outcome measures.
    Pain, 2000, Dec-01, Volume: 88, Issue:3

    Topics: Analgesics, Opioid; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Confidenc

2000
Defining the clinically important difference in pain outcome measures.
    Pain, 2000, Dec-01, Volume: 88, Issue:3

    Topics: Analgesics, Opioid; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Confidenc

2000
Defining the clinically important difference in pain outcome measures.
    Pain, 2000, Dec-01, Volume: 88, Issue:3

    Topics: Analgesics, Opioid; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Confidenc

2000
Defining the clinically important difference in pain outcome measures.
    Pain, 2000, Dec-01, Volume: 88, Issue:3

    Topics: Analgesics, Opioid; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Confidenc

2000
Defining the clinically important difference in pain outcome measures.
    Pain, 2000, Dec-01, Volume: 88, Issue:3

    Topics: Analgesics, Opioid; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Confidenc

2000
Defining the clinically important difference in pain outcome measures.
    Pain, 2000, Dec-01, Volume: 88, Issue:3

    Topics: Analgesics, Opioid; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Confidenc

2000
Defining the clinically important difference in pain outcome measures.
    Pain, 2000, Dec-01, Volume: 88, Issue:3

    Topics: Analgesics, Opioid; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Confidenc

2000
Defining the clinically important difference in pain outcome measures.
    Pain, 2000, Dec-01, Volume: 88, Issue:3

    Topics: Analgesics, Opioid; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Confidenc

2000
Defining the clinically important difference in pain outcome measures.
    Pain, 2000, Dec-01, Volume: 88, Issue:3

    Topics: Analgesics, Opioid; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Confidenc

2000
Defining the clinically important difference in pain outcome measures.
    Pain, 2000, Dec-01, Volume: 88, Issue:3

    Topics: Analgesics, Opioid; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Confidenc

2000
Opioids in non-cancer pain: a life-time sentence?
    European journal of pain (London, England), 2001, Volume: 5, Issue:3

    Topics: Administration, Cutaneous; Adult; Aged; Analgesics, Opioid; Chronic Disease; Diabetic Neuropathies;

2001
Sufentanil citrate and morphine/bupivacaine as alternative agents in chronic epidural infusions for intractable non-cancer pain.
    Neurosurgery, 1991, Volume: 29, Issue:1

    Topics: Analgesia, Epidural; Analgesics; Bupivacaine; Drug Combinations; Drug Evaluation; Fentanyl; Humans;

1991

Other Studies

60 other studies available for fentanyl and Pain, Intractable

ArticleYear
[Pain therapy. Treating pain patients with opioid preparations].
    MMW Fortschritte der Medizin, 2013, Apr-04, Volume: 155, Issue:6

    Topics: Administration, Cutaneous; Analgesics, Opioid; Chronic Pain; Cooperative Behavior; Drug Therapy, Com

2013
[Fentanyl: fast and furious?].
    Der Anaesthesist, 2013, Volume: 62, Issue:6

    Topics: Analgesics, Opioid; Breakthrough Pain; Fentanyl; Humans; Neoplasms; Pain; Pain, Intractable

2013
[Transdermal fentanyl patch for the treatment of chronic intractable pain].
    Masui. The Japanese journal of anesthesiology, 2013, Volume: 62, Issue:7

    Topics: Analgesics, Opioid; Chronic Pain; Fentanyl; Humans; Pain, Intractable; Transdermal Patch

2013
[Opioid combination of transdermal fentanyl and oral oxycodone for pain in a patient with giant-cell tumor of the sacrum].
    Masui. The Japanese journal of anesthesiology, 2014, Volume: 63, Issue:2

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Analgesics, Opioid; Bone Neoplasms; Drug Adm

2014
[The cognitive effects of using transdermal fentanyl in cancer pain].
    Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology, 2014, Volume: 26, Issue:3

    Topics: Administration, Cutaneous; Analgesics, Opioid; Cognition Disorders; Female; Fentanyl; Humans; Male;

2014
Successful Management of Corneal Neuropathic Pain with Intrathecal Targeted Drug Delivery.
    Pain medicine (Malden, Mass.), 2016, Volume: 17, Issue:7

    Topics: Adult; Analgesics; Bupivacaine; Cervical Vertebrae; Cornea; Female; Fentanyl; Humans; Infusion Pumps

2016
Use of a fentanyl patch throughout pregnancy.
    Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC, 2009, Volume: 31, Issue:1

    Topics: Administration, Cutaneous; Analgesics, Opioid; Female; Fentanyl; Fetus; Humans; Pain, Intractable; P

2009
Feasibility study of direct fentanyl patch introduction without prior opioid titration.
    International journal of clinical oncology, 2009, Volume: 14, Issue:3

    Topics: Administration, Cutaneous; Aged; Analgesics, Opioid; Feasibility Studies; Female; Fentanyl; Gastroin

2009
[A case of unresectable advanced pancreatic cancer treated by gemcitabine-based chemotherapy following cancer pain alleviation by low-dose matrix-type transdermal fentanyl].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:8

    Topics: Administration, Cutaneous; Aged; Antimetabolites, Antineoplastic; Deoxycytidine; Female; Fentanyl; G

2009
Validated LC coupled to ESI-MS/MS analysis for fentanyl in human plasma and UV analysis in applied reservoir transdermal patches using a simple and rapid procedure.
    Journal of clinical pharmacy and therapeutics, 2009, Volume: 34, Issue:5

    Topics: Administration, Cutaneous; Calibration; Chromatography, Liquid; Drug Stability; Fentanyl; Humans; Ne

2009
Danish pain specialists' rationales behind the choice of fentanyl transdermal patches and oral transmucosal systems--a delphi study.
    Pain medicine (Malden, Mass.), 2009, Volume: 10, Issue:8

    Topics: Administration, Cutaneous; Administration, Oral; Analgesics, Opioid; Data Collection; Decision Suppo

2009
Fentanyl effervescent buccal tablets: new formulation. For cancer patients with breakthrough pain: a second buccal formulation with minimal evaluation.
    Prescrire international, 2009, Volume: 18, Issue:103

    Topics: Administration, Buccal; Analgesics, Opioid; Biological Availability; Chemistry, Pharmaceutical; Dosa

2009
Fentanyl sublingual tablets. Breakthrough pain: new formulation, no therapeutic advantage.
    Prescrire international, 2010, Volume: 19, Issue:105

    Topics: Administration, Sublingual; Analgesics, Opioid; Chemistry, Pharmaceutical; Fentanyl; Humans; Neoplas

2010
Treatment of severe cancer pain by transdermal fentanyl.
    Bosnian journal of basic medical sciences, 2010, Volume: 10, Issue:2

    Topics: Administration, Cutaneous; Adult; Aged; Analgesics, Opioid; Bone Neoplasms; Female; Fentanyl; Hemody

2010
[Serotoninergic antidepressants and opiate analgesics: a sometimes-painful association. A case report].
    L'Encephale, 2010, Volume: 36 Suppl 2

    Topics: Adenocarcinoma; Administration, Intranasal; Administration, Oral; Aged; Analgesics, Opioid; Antidepr

2010
[Comparison of transdermal fentanyl for the management of cancer pain in adults and elders].
    Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology, 2012, Volume: 24, Issue:3

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Female; Fentanyl; Hum

2012
A simple liquid chromatography-tandem mass spectrometry method for determination of plasma fentanyl concentration in rats and patients with cancer pain.
    Biological & pharmaceutical bulletin, 2013, Volume: 36, Issue:3

    Topics: Aged; Analgesics, Opioid; Animals; Chromatography, Liquid; Female; Fentanyl; Humans; Male; Middle Ag

2013
A prospective study evaluating the response of patients with unrelieved cancer pain to parenteral opioids.
    Cancer, 2002, Jun-01, Volume: 94, Issue:11

    Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Codeine; Female; Fentany

2002
[Clinical study on treatment of protracted pain by continuously administering different dose of fentanyl by ocupoint embedding micropump].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2001, Volume: 21, Issue:6

    Topics: Acupuncture Points; Adult; Aged; Analgesics, Opioid; Female; Fentanyl; Humans; Infusion Pumps, Impla

2001
The importance of the complete history in the discovery of a potential suicide: a case report.
    Archives of physical medicine and rehabilitation, 2003, Volume: 84, Issue:3

    Topics: Acetates; Amines; Analgesics, Opioid; Anti-Anxiety Agents; Anti-Bacterial Agents; Cyclohexanecarboxy

2003
Long-term cancer pain management in morphine pre-treated and opioid naive patients with transdermal fentanyl.
    International journal of cancer, 2003, Nov-10, Volume: 107, Issue:3

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Female; Fentanyl; Humans; Male; Middle Ag

2003
[Transdermal fentanyl for the management of cancer pain: a survey of 1,664 elderly patients].
    Zhonghua yi xue za zhi, 2003, Nov-25, Volume: 83, Issue:22

    Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Analgesics, Opioid; Female; Fentanyl; Humans; Ma

2003
Correlation between withdrawal symptoms and medication pump residual volume in patients with implantable SynchroMed pumps.
    Neurosurgery, 2004, Volume: 55, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Analgesia, Epidural; Analgesics, Opioid; Baclofen; Bupivacaine; Clon

2004
[Usefulness of fentanyl patch in home palliative care].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:1 Suppl

    Topics: Administration, Cutaneous; Adult; Aged; Analgesics, Opioid; Fentanyl; Home Care Services; Humans; Mi

2003
[Home palliative care--2 case reports: a long-term cancer pain management with transdermal fentanyl].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31 Suppl 2

    Topics: Administration, Cutaneous; Aged; Analgesics, Opioid; Female; Fentanyl; Gastrointestinal Neoplasms; H

2004
[Parenteral opioids in end-of-life care in cancer patients].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:2

    Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Delayed-Action Preparations; Drug Administration

2005
[Challenges in the treatment of pain in children with cancer and tunneling of epidural catheter for long term infusion].
    Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology, 2005, Volume: 17, Issue:1

    Topics: Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Bone Neoplasms; Bupivacaine; Catheteriz

2005
Chronic fentanyl application induces adrenocortical insufficiency.
    Journal of internal medicine, 2005, Volume: 257, Issue:5

    Topics: Administration, Cutaneous; Adrenal Insufficiency; Anti-Inflammatory Agents; Drug Administration Sche

2005
[Transdermal fentanyl for the management of cancer pain: a survey of 4492 patients].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2005, Volume: 27, Issue:6

    Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Child; Ch

2005
[The opioid combination of transdermal fentanyl and sustained release morphine for refractory cancer pain--a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:12

    Topics: Administration, Cutaneous; Adult; Analgesics, Opioid; Delayed-Action Preparations; Drug Therapy, Com

2005
[Direct conversion from low-dose morphine to transdermal fentanyl: efficacy for cancer pain and quality of life].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:2

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Analgesia; Analgesics, Opioid; Female; Fe

2006
[A case of long-term, high-dose transdermal fentanyl application for lung cancer pain].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:3

    Topics: Administration, Cutaneous; Analgesics, Opioid; Bone Neoplasms; Female; Fentanyl; Humans; Lung Neopla

2006
Patterns of dosage changes with transdermal buprenorphine and transdermal fentanyl for the treatment of noncancer and cancer pain: a retrospective data analysis in Germany.
    Clinical therapeutics, 2006, Volume: 28, Issue:8

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Buprenorphine; Dose-R

2006
[Usefulness of fentanyl patch (Durotep) in cancer patients when rotated from morphine preparations].
    Masui. The Japanese journal of anesthesiology, 2007, Volume: 56, Issue:3

    Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Analgesics, Opioid; Female; Fentanyl; Humans; Ma

2007
[Transdermal fentanyl for neuropathic pain: a case report].
    Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology, 2006, Volume: 18, Issue:4

    Topics: Administration, Cutaneous; Adult; Analgesics, Opioid; Female; Fentanyl; Humans; Neuralgia; Pain, Int

2006
Opioid plasma concentrations during a switch from transdermal fentanyl to methadone.
    Journal of palliative medicine, 2007, Volume: 10, Issue:2

    Topics: Administration, Cutaneous; Adult; Aged; Analgesics, Opioid; Drug Administration Schedule; Female; Fe

2007
The impact of the opioids fentanyl and morphine on nociception and bone destruction in a murine model of bone cancer pain.
    Pharmacology, biochemistry, and behavior, 2007, Volume: 87, Issue:1

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Body Weight; Bone and Bones; Bone Neoplasms; Femur; F

2007
[Validity of recommended minimum dose of prior morphine to initiate transdermal fentanyl patch in prescribing information - multicenter survey of on prescriptions by palliative care specialists in Japan].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:6

    Topics: Administration, Cutaneous; Administration, Oral; Analgesics, Opioid; Drug Prescriptions; Fentanyl; H

2007
Switching from transdermal drugs: an observational "N of 1" study of fentanyl and buprenorphine.
    Journal of pain and symptom management, 2007, Volume: 34, Issue:5

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Aged; Analgesics, Opioid; Buprenorphine; Fem

2007
[Feasibility to treat pediatric cancer pain with analgesics for adults and their efficacy].
    Ai zheng = Aizheng = Chinese journal of cancer, 2007, Volume: 26, Issue:8

    Topics: Adolescent; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Co

2007
[Evaluation of the 2.5 mg fentanyl patch, applied using the half-side application procedure in patients with cancer pain].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2008, Volume: 128, Issue:3

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Female; Fentanyl; Human

2008
Epidural fentanyl for pain of multiple fractures.
    Lancet (London, England), 1980, Nov-08, Volume: 2, Issue:8202

    Topics: Aged; Anesthesia, Epidural; Female; Femoral Fractures; Fentanyl; Humans; Pain, Intractable

1980
Strong analgesics in severe pain.
    Drugs, 1984, Volume: 28, Issue:1

    Topics: Analgesics, Opioid; Chronic Disease; Cocaine; Fentanyl; Half-Life; Heroin; Humans; Injections, Intra

1984
An improved technique for alcohol neurolysis of the celiac plexus.
    Anesthesiology, 1982, Volume: 56, Issue:2

    Topics: Abdominal Neoplasms; Anesthesia, Local; Celiac Plexus; Chronic Disease; Crohn Disease; Denervation;

1982
Withdrawal symptoms during therapy with transdermal fentanyl (fentanyl TTS)?
    Journal of pain and symptom management, 1994, Volume: 9, Issue:1

    Topics: Administration, Cutaneous; Adult; Colonic Neoplasms; Female; Fentanyl; Humans; Middle Aged; Morphine

1994
Continuous intravenous infusion of fentanyl: case reports of use in patients with advanced cancer and intractable pain.
    Journal of pain and symptom management, 1993, Volume: 8, Issue:4

    Topics: Adult; Female; Fentanyl; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasms; Pain, Intract

1993
Titration with TTS fentanyl systems for previously uncontrolled cancer pain.
    Anesthesia and analgesia, 1994, Volume: 79, Issue:3

    Topics: Administration, Cutaneous; Fentanyl; Humans; Neoplasms; Pain, Intractable

1994
Oral morphine termed narcotic standard in severe cancer pain.
    Oncology (Williston Park, N.Y.), 1996, Volume: 10, Issue:2

    Topics: Administration, Oral; Analgesics, Opioid; Delayed-Action Preparations; Fentanyl; Humans; Morphine; N

1996
Nurse-controlled analgesia using a patient-controlled analgesia device: an alternative strategy in the management of severe cancer pain in children.
    Journal of paediatrics and child health, 1997, Volume: 33, Issue:4

    Topics: Adolescent; Analgesia, Patient-Controlled; Analgesics, Opioid; Child; Child, Preschool; Dose-Respons

1997
Prolonged central intravenous ketorolac continuous infusion in a cancer patient with intractable bone pain.
    The Annals of pharmacotherapy, 1998, Volume: 32, Issue:2

    Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Bone Neoplasms; Carcinoma, Non-Small-Cell Lung; Cathet

1998
Managing breakthrough pain with OTFC.
    The American journal of nursing, 1999, Volume: 99, Issue:4

    Topics: Administration, Oral; Analgesics, Opioid; Drug Delivery Systems; Fentanyl; Humans; Pain, Intractable

1999
An assessment of the safety, efficacy, and acceptability of intranasal fentanyl citrate in the management of cancer-related breakthrough pain: a pilot study.
    Journal of pain and symptom management, 2000, Volume: 20, Issue:4

    Topics: Administration, Intranasal; Aged; Aged, 80 and over; Analgesia; Dose-Response Relationship, Drug; Dr

2000
Inefficacy of high-dose transdermal fentanyl in a patient with neuropathic pain, a case report.
    European journal of pain (London, England), 2001, Volume: 5, Issue:3

    Topics: Administration, Cutaneous; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Breast Neopl

2001
Intravenous methadone in the management of chronic cancer pain: safe and effective starting doses when substituting methadone for fentanyl.
    Cancer, 2001, Oct-01, Volume: 92, Issue:7

    Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Drug Administration Schedule; Female

2001
More on end-of-life care.
    The Journal of the American Osteopathic Association, 2002, Volume: 102, Issue:2

    Topics: Absorption; Administration, Oral; Analgesics, Opioid; Fentanyl; Humans; Mouth Mucosa; Pain Measureme

2002
Pain in Spain could be on the wane.
    The Lancet. Oncology, 2002, Volume: 3, Issue:1

    Topics: Administration, Cutaneous; Analgesics, Opioid; Female; Fentanyl; Humans; Male; Neoplasms; Pain Measu

2002
An open label study of oral transmucosal fentanyl citrate (OTFC) for the treatment of breakthrough cancer pain.
    Pain, 1991, Volume: 45, Issue:2

    Topics: Administration, Oral; Adult; Aged; Blood Pressure; Fentanyl; Humans; Middle Aged; Mouth Mucosa; Neop

1991
Oral transmucosal fentanyl citrate for the treatment of breakthrough cancer pain: a case report.
    Anesthesiology, 1989, Volume: 71, Issue:4

    Topics: Absorption; Administration, Oral; Fentanyl; Humans; Male; Middle Aged; Mouth Mucosa; Neoplasms; Pain

1989
[Morphologic and histologic changes caused by continuous peridural analgesia in a cancer patient].
    Regional-Anaesthesie, 1986, Volume: 9, Issue:2

    Topics: Adenocarcinoma; Anesthesia, Epidural; Bupivacaine; Catheters, Indwelling; Colonic Neoplasms; Fentany

1986
Physiological guidelines for the localization of lesions by percutaneous cordotomy.
    Acta neurochirurgica, 1974, Volume: Suppl 21

    Topics: Anesthesia, Local; Cordotomy; Electric Stimulation; Female; Fentanyl; Humans; Pain, Intractable; Rec

1974