fentanyl has been researched along with Osteoarthritis, Knee in 9 studies
Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.
Osteoarthritis, Knee: Noninflammatory degenerative disease of the knee joint consisting of three large categories: conditions that block normal synchronous movement, conditions that produce abnormal pathways of motion, and conditions that cause stress concentration resulting in changes to articular cartilage. (Crenshaw, Campbell's Operative Orthopaedics, 8th ed, p2019)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the effectiveness and safety of transdermal fentanyl (TDF) for the treatment of pain associated with rheumatoid arthritis (RA) or osteoarthritis of the knee or hip (OA), which was not adequately controlled by non-opioid analgesics and/or weak opioids." | 9.11 | Benefits of transdermal fentanyl in patients with rheumatoid arthritis or with osteoarthritis of the knee or hip: an open-label study to assess pain control. ( Bjorneboe, O; Herrero-Beaumont, G; Le Loet, X; Pavelka, K; Richarz, U, 2004) |
| "This study was designed to evaluate the utility of transdermal fentanyl (TDF, Durogesic) for the treatment of pain due to osteoarthritis (OA) of the knee or hip, which was not adequately controlled by non-opioid analgesics or weak opioids." | 9.11 | Transdermal fentanyl for the treatment of pain caused by osteoarthritis of the knee or hip: an open, multicentre study. ( Le Loët, X; Pavelka, K; Richarz, U, 2005) |
| "Although common treatments for osteoarthritis (OA) pain, such as nonsteroidal antiinflammatory drugs (NSAIDs), simple analgesics, and weak opioids, provide relief in some cases, they fail to control pain or are poorly tolerated in many cases." | 6.72 | Transdermal fentanyl for improvement of pain and functioning in osteoarthritis: a randomized, placebo-controlled trial. ( Langford, R; McKenna, F; Ratcliffe, S; Richarz, U; Vojtassák, J, 2006) |
| "To evaluate the effectiveness and safety of transdermal fentanyl (TDF) for the treatment of pain associated with rheumatoid arthritis (RA) or osteoarthritis of the knee or hip (OA), which was not adequately controlled by non-opioid analgesics and/or weak opioids." | 5.11 | Benefits of transdermal fentanyl in patients with rheumatoid arthritis or with osteoarthritis of the knee or hip: an open-label study to assess pain control. ( Bjorneboe, O; Herrero-Beaumont, G; Le Loet, X; Pavelka, K; Richarz, U, 2004) |
| "This study was designed to evaluate the utility of transdermal fentanyl (TDF, Durogesic) for the treatment of pain due to osteoarthritis (OA) of the knee or hip, which was not adequately controlled by non-opioid analgesics or weak opioids." | 5.11 | Transdermal fentanyl for the treatment of pain caused by osteoarthritis of the knee or hip: an open, multicentre study. ( Le Loët, X; Pavelka, K; Richarz, U, 2005) |
| " Efficacy, adverse effects (AEs), dosing regimens, physician expertise and patient preference influence treatment selection." | 2.73 | Transdermal fentanyl improves pain control and functionality in patients with osteoarthritis: an open-label Canadian trial. ( Camacho, F; Choquette, D; Horbay, GL; Husein-Bhabha, FA; Kelly, AJ; McCarthy, TG; Rodrigues, JF, 2008) |
| "Although common treatments for osteoarthritis (OA) pain, such as nonsteroidal antiinflammatory drugs (NSAIDs), simple analgesics, and weak opioids, provide relief in some cases, they fail to control pain or are poorly tolerated in many cases." | 2.72 | Transdermal fentanyl for improvement of pain and functioning in osteoarthritis: a randomized, placebo-controlled trial. ( Langford, R; McKenna, F; Ratcliffe, S; Richarz, U; Vojtassák, J, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Högl, B | 1 |
| Lohner, H | 1 |
| Mikus, G | 1 |
| Huff, H | 1 |
| Fujii, T | 1 |
| Takana, K | 1 |
| Orita, S | 1 |
| Inoue, G | 1 |
| Ochiai, N | 1 |
| Kuniyoshi, K | 1 |
| Aoki, Y | 1 |
| Ishikawa, T | 1 |
| Miyagi, M | 1 |
| Kamoda, H | 1 |
| Suzuki, M | 1 |
| Sakuma, Y | 1 |
| Kubota, G | 1 |
| Oikawa, Y | 1 |
| Inage, K | 1 |
| Sainoh, T | 1 |
| Sato, J | 1 |
| Yamauchi, K | 1 |
| Toyone, T | 1 |
| Nakamura, J | 1 |
| Kishida, S | 1 |
| Takahashi, K | 1 |
| Ohtori, S | 1 |
| Mullaji, A | 1 |
| Kanna, R | 1 |
| Shetty, GM | 1 |
| Chavda, V | 1 |
| Singh, DP | 1 |
| McMeniman, TJ | 1 |
| McMeniman, PJ | 1 |
| Myers, PT | 1 |
| Hayes, DA | 1 |
| Cavdarski, A | 1 |
| Wong, MS | 1 |
| Wilson, AJ | 1 |
| Jones, MA | 1 |
| Watts, MC | 1 |
| Pavelka, K | 2 |
| Le Loet, X | 2 |
| Bjorneboe, O | 1 |
| Herrero-Beaumont, G | 1 |
| Richarz, U | 3 |
| Langford, R | 1 |
| McKenna, F | 1 |
| Ratcliffe, S | 1 |
| Vojtassák, J | 1 |
| Barron, MC | 1 |
| Rubin, BR | 1 |
| Choquette, D | 1 |
| McCarthy, TG | 1 |
| Rodrigues, JF | 1 |
| Kelly, AJ | 1 |
| Camacho, F | 1 |
| Horbay, GL | 1 |
| Husein-Bhabha, FA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Pre-emptive Scalp Infiltration With Ropivacaine and Methylprednisolone- Ropivacaine on Pain After Craniotomy in Adults[NCT04078139] | Phase 4 | 188 participants (Anticipated) | Interventional | 2021-03-05 | Not yet recruiting | ||
| Efficacy of Pain Management in Different Concentrations of Bupivacaine in Periarticular Injection and Plasma Concentrations of Bupivacaine in Patients Undergoing Bilateral Knee Arthroplasty[NCT03249662] | 60 participants (Actual) | Interventional | 2017-09-27 | Completed | |||
| [NCT01593319] | Phase 4 | 37 participants (Actual) | Interventional | 2012-01-31 | Terminated | ||
| Open-Label Study To Assess The Effect On Pain Control Of Durogesic (Fentanyl Transdermic Therapeutic System) Treatment In Subjects With Rheumatoid Arthritis Or Osteoarthritis Of The Knee Or Hip.[NCT00524160] | Phase 4 | 264 participants (Actual) | Interventional | 2001-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for fentanyl and Osteoarthritis, Knee
| Article | Year |
|---|---|
Managing osteoarthritic knee pain.
Topics: Acupuncture Therapy; Adjuvants, Immunologic; Aged; Algorithms; Analgesics, Opioid; Anti-Inflammatory | 2007 |
7 trials available for fentanyl and Osteoarthritis, Knee
| Article | Year |
|---|---|
Progressive change in joint degeneration in patients with knee or hip osteoarthritis treated with fentanyl in a randomized trial.
Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Disease Progression; Female; Fentanyl; Humans; Male; Mi | 2014 |
Efficacy of periarticular injection of bupivacaine, fentanyl, and methylprednisolone in total knee arthroplasty:a prospective, randomized trial.
Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Anesthetics, Combined; Anesthetics, Local; Arthroplasty | 2010 |
Efficacy of periarticular injection of bupivacaine, fentanyl, and methylprednisolone in total knee arthroplasty:a prospective, randomized trial.
Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Anesthetics, Combined; Anesthetics, Local; Arthroplasty | 2010 |
Efficacy of periarticular injection of bupivacaine, fentanyl, and methylprednisolone in total knee arthroplasty:a prospective, randomized trial.
Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Anesthetics, Combined; Anesthetics, Local; Arthroplasty | 2010 |
Efficacy of periarticular injection of bupivacaine, fentanyl, and methylprednisolone in total knee arthroplasty:a prospective, randomized trial.
Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Anesthetics, Combined; Anesthetics, Local; Arthroplasty | 2010 |
Femoral nerve block vs fascia iliaca block for total knee arthroplasty postoperative pain control: a prospective, randomized controlled trial.
Topics: Aged; Anesthetics, Intravenous; Arthroplasty, Replacement, Knee; Female; Femoral Nerve; Fentanyl; Hu | 2010 |
Benefits of transdermal fentanyl in patients with rheumatoid arthritis or with osteoarthritis of the knee or hip: an open-label study to assess pain control.
Topics: Administration, Cutaneous; Aged; Analgesics, Opioid; Arthritis, Rheumatoid; Female; Fentanyl; Humans | 2004 |
Transdermal fentanyl for the treatment of pain caused by osteoarthritis of the knee or hip: an open, multicentre study.
Topics: Administration, Cutaneous; Analgesics, Opioid; Dose-Response Relationship, Drug; Fentanyl; Humans; M | 2005 |
Transdermal fentanyl for improvement of pain and functioning in osteoarthritis: a randomized, placebo-controlled trial.
Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Female; Fentanyl; Hum | 2006 |
Transdermal fentanyl improves pain control and functionality in patients with osteoarthritis: an open-label Canadian trial.
Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Canada; Female; Fenta | 2008 |
1 other study available for fentanyl and Osteoarthritis, Knee
| Article | Year |
|---|---|
Acute and painful exacerbation of RLS and PLM induced by opioid interaction - withdrawal syndrome.
Topics: Aged, 80 and over; Analgesics, Opioid; Drug Combinations; Fentanyl; Humans; Male; Naloxone; Nocturna | 2017 |