fentanyl has been researched along with Opiate Overdose in 69 studies
Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.
Opiate Overdose: Accidental or deliberate use of an OPIOID in excess of normal dosage. It includes overdose for prescription and illicit opioids.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A large percentage of opioid overdose fatalities involve fentanyl or one of its legal or illegal analogs (F/FAs)." | 5.62 | Wooden Chest syndrome: The atypical pharmacology of fentanyl overdose. ( Ann LeQuang, J; Pergolizzi, JV; Raffa, RB; Vortsman, E; Webster, LR, 2021) |
| "Illicit opioids, consisting largely of fentanyl, novel synthetic opioids, and adulterants, are the primary cause of drug overdose fatality in the United States." | 4.31 | Opioid overdoses involving xylazine in emergency department patients: a multicenter study. ( Aldy, K; Amaducci, A; Brent, J; Calello, D; Hendrickson, R; Hughes, A; Judge, B; Krotulski, AJ; Kurt, A; Levine, M; Logan, BK; Love, JS; Manini, AF; Pizon, A; Schwarz, E; Shulman, J; Vargas-Torres, C; Walton, SE; Wax, P; Wiegan, T, 2023) |
| "In 2022, provisional data indicated that more than two thirds (68%) of the reported 107,081 drug overdose deaths in the United States involved synthetic opioids other than methadone, principally illicitly manufactured fentanyls (IMFs) (1)." | 4.31 | Illicitly Manufactured Fentanyl-Involved Overdose Deaths with Detected Xylazine - United States, January 2019-June 2022. ( Goldberger, BA; Kariisa, M; Kumar, S; Mattson, CL; O'Donnell, J, 2023) |
| "Positive responses to a fentanyl vaccine were found along with appreciation for the complexity of a vaccine strategy to prevent OD in the setting of pain and uncertain durability." | 4.12 | Acceptability of a Fentanyl Vaccine to Prevent Opioid Overdose and Need for Personalized Decision-Making. ( Blakemore, LM; Cox, R; Dowling, DJ; Kossowsky, J; Levy, O; Levy, S; Needles, EW; Weitzman, ER, 2022) |
| "Naloxone is the primary opioid overdose reversal agent, but concern has been raised that naloxone is not efficacious against the pervasive illicit high potency opioids (i." | 2.82 | Treatment of opioid overdose: current approaches and recent advances. ( Britch, SC; Walsh, SL, 2022) |
| "There is little scientific evidence that supports the use of initial systemic dosing that exceeds 0." | 2.82 | Pharmacokinetic considerations for community-based dosing of nasal naloxone in opioid overdose in adults. ( Dale, O, 2022) |
| "The increasing number of opioid overdoses in North America especially is an indication of changing drug markets and failing regional systems of care." | 2.72 | The opioid overdose crisis as a global health challenge. ( Krausz, RM; Westenberg, JN; Ziafat, K, 2021) |
| " High-quality comparative naloxone dosing studies assessing effectiveness and safety are needed." | 2.66 | Naloxone dosing in the era of ultra-potent opioid overdoses: a systematic review. ( Brasher, PMA; Buxton, JA; Curran, J; Doyle-Waters, MM; Godwin, J; Hau, JP; Hohl, CM; Moe, J; O'Sullivan, F; Purssell, E; Purssell, R, 2020) |
| "Opioid use disorder and opioid overdose continue to be significant public health challenges despite the availability of effective treatments." | 2.44 | Daily methocinnamox treatment dose-dependently attenuates fentanyl self-administration in rhesus monkeys. ( France, CP; Maguire, DR, 2024) |
| "Among inpatients with opioid use disorder, fentanyl status does not appear to be statistically significantly associated with Clinical Opioid Withdrawal Scale and Short Opiate Withdrawal Scale mean and maximum scores." | 1.91 | Fentanyl withdrawal: Understanding symptom severity and exploring the role of body mass index on withdrawal symptoms and clearance. ( Choi, CJ; Comer, S; Jones, J; Luba, R, 2023) |
| "Heroin caused prolonged (45-60 minute) respiratory depression in female and male rats, characterized by decreased frequency, tidal volume, and minute ventilation and increased inspiratory time and apneic pause." | 1.91 | Heroin- and Fentanyl-Induced Respiratory Depression in a Rat Plethysmography Model: Potency, Tolerance, and Sex Differences. ( Carlson, ER; Frye, EV; Hampson, A; Hastings, LE; Koob, GF; Lewis, SJ; Marchette, RCN; Mejias-Torres, G; Vendruscolo, JCM; Vendruscolo, LF; Volkow, ND, 2023) |
| "Fentanyl test strips are a novel drug checking tool that can be used by people who use drugs to detect the presence of fentanyl in drug products." | 1.91 | Differences in drug use behaviors that impact overdose risk among individuals who do and do not use fentanyl test strips for drug checking. ( Baltes, A; Brown, R; Malicki, J; Salisbury-Afshar, E; Tilhou, AS; Zaborek, J, 2023) |
| "They indicated lower perceived risk of opioid overdose (0." | 1.91 | Attitudes and experiences with fentanyl contamination of methamphetamine: exploring self-reports and urine toxicology among persons who use methamphetamine and other drugs. ( Daniulaityte, R; Juhascik, M; Ruhter, L; Silverstein, S, 2023) |
| "In this cohort study of patients admitted to the ED with confirmed opioid overdose testing positive for NPOs, in-hospital naloxone dosing was high compared with patients who tested positive for fentanyl alone." | 1.91 | Naloxone Use in Novel Potent Opioid and Fentanyl Overdoses in Emergency Department Patients. ( Abston, S; Aldy, K; Amaducci, A; Brent, J; Campleman, SL; Culbreth, RE; Krotulski, A; Li, S; Logan, B; Manini, AF; Meyn, A; Wax, P, 2023) |
| "Number of opioid overdose deaths, people incarcerated, and associated costs over 5 years." | 1.91 | Mortality, incarceration and cost implications of fentanyl felonization laws: A modeling study. ( Barocas, JA; Gonsalves, G; Jurecka, C; Savinkina, A, 2023) |
| "Fentanyl was defined as probable or suspected IMF or probable pharmaceutical fentanyl." | 1.72 | Using death scene and toxicology evidence to define involvement of heroin, pharmaceutical morphine, illicitly manufactured fentanyl and pharmaceutical fentanyl in opioid overdose deaths, 38 states and the District of Columbia, January 2018-December 2019. ( Gladden, RM; Kariisa, M; Mattson, CL; O'Donnell, J, 2022) |
| "Fentanyl has replaced most other non-prescribed opioids in much of North America." | 1.72 | Modeling of overdose and naloxone distribution in the setting of fentanyl compared to heroin. ( Coffin, PO; Kahn, JG; Maya, S, 2022) |
| " Prior research has assessed the effectiveness of naloxone in the hospital setting; however, it is challenging to assess naloxone dosing regimens in the community/first-responder setting, including reversal of respiratory depression effects of fentanyl and its derivatives (fentanyls)." | 1.72 | Development of a Translational Model to Assess the Impact of Opioid Overdose and Naloxone Dosing on Respiratory Depression and Cardiac Arrest. ( Ahmadi, SF; Bloom, S; Chaturbedi, A; Dahan, A; Eshleman, A; Florian, J; Han, X; Janowsky, A; Li, Z; Mann, J; Olofsen, E; Samieegohar, M; Strauss, DG; Swanson, T; Wolfrum, K; Zirkle, J, 2022) |
| "The proportion of opioid overdose deaths increased by 36% post-COVID emergence (95% CI: 14%, 59%)." | 1.72 | Impact of COVID-19 on the characteristics of opioid overdose deaths in Arkansas. ( Fairman, BJ; Rezaeiahari, M, 2022) |
| "They had a higher prevalence of chronic pain (35." | 1.72 | Individuals Dying of Overdoses Related to Pharmaceutical Opioids Differ from Individuals Dying of Overdoses Related to Other Substances: A Population-Based Register Study. ( Clausen, T; Gjersing, L; Hamina, A; Handal, M; Lid, TG; Odsbu, I; Skurtveit, S, 2022) |
| "Naloxone was felt to be effective by the LEO in 370 (62%) of these cases with 6 (1%) exhibiting combativeness and 57 (10%) having the composite outcome of irritability or combativeness." | 1.72 | Outcomes of law enforcement officer administered naloxone. ( Colella, MR; Farkas, A; Gooley, B; Weston, B, 2022) |
| "Fentanyl is an analgesic that is frequently prescribed, which resulted in non-intentional as well as intentional misuse and deaths." | 1.72 | Case report on postmortem fentanyl measurement after overdose with more than 67 fentanyl patches. ( Bethlehem, C; Croes, EA; Peeters, LEJ; Tan, GE; Vleut, IT, 2022) |
| "Pre-treatment with naloxone (1 mg/kg) prevented fentanyl-induced VCC, but naloxone (1 and 2 mg/kg) was unable to reverse VCC when administered after fentanyl." | 1.62 | Fentanyl causes naloxone-resistant vocal cord closure: A platform for testing opioid overdose treatments. ( Janowsky, A; Miner, NB; Schutzer, WE; Torralva, R; Zarnegarnia, Y, 2021) |
| "A large percentage of opioid overdose fatalities involve fentanyl or one of its legal or illegal analogs (F/FAs)." | 1.62 | Wooden Chest syndrome: The atypical pharmacology of fentanyl overdose. ( Ann LeQuang, J; Pergolizzi, JV; Raffa, RB; Vortsman, E; Webster, LR, 2021) |
| "Medically treated opioid overdoses identify a population at high risk of subsequent mortality and need for treatment." | 1.62 | Medically treated opioid overdoses among New Jersey Medicaid beneficiaries: Rapid growth and complex comorbidity amid growing fentanyl penetration. ( Crystal, S; Nowels, M; Olfson, M; Samples, H; Treitler, P; Williams, AR, 2021) |
| "Opioid overdose has become the leading cause of death among adults between 25 and 54 years old in the U." | 1.56 | The protective effect of trusted dealers against opioid overdose in the U.S. ( Carroll, JJ; Green, TC; Rich, JD, 2020) |
| "Although limited literature has shown leukoencephalopathy to be associated with opioid overdose, we present a case of additional involvement of subcortical gray matter." | 1.56 | Diffuse subcortical white matter injury and bilateral basal ganglia neuronal loss after acute opioid overdose. ( Chaudhari, A; Dinicu, AI; Kayyal, S, 2020) |
| "Fentanyl analogs have been identified as important contributors to these overdoses, but little is known about their prevalence in patients seeking health care." | 1.56 | Fentanyl analog positivity among near-real-time urine drug test results in patients seeking health care. ( Bundy, WL; Dawson, E; Huskey, A; LaRue, L; Stanton, JD; Whitley, P, 2020) |
| "From 2013 to 2017, the overall opioid overdose mortality rate was consistently higher in NH white Americans, however, the rate increase was greater among NH Black (174 %) compared to NH white (85 %) Americans." | 1.56 | Opioid-related overdose mortality in the era of fentanyl: Monitoring a shifting epidemic by person, place, and time. ( Althoff, KN; Chandran, A; Leifheit, KM; Park, JN; Sherman, SG, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 69 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cruz, SL | 1 |
| Carranza-Aguilar, CJ | 1 |
| Pérez-García, IP | 1 |
| Wightman, RS | 1 |
| Perrone, J | 1 |
| Scagos, R | 2 |
| Hallowell, BD | 1 |
| Krieger, M | 1 |
| Li, Y | 1 |
| McGregor, AJ | 1 |
| Nelson, LS | 1 |
| Marshall, BDL | 3 |
| Miner, NB | 1 |
| Schutzer, WE | 1 |
| Zarnegarnia, Y | 1 |
| Janowsky, A | 2 |
| Torralva, R | 1 |
| Daniulaityte, R | 2 |
| Silverstein, SM | 1 |
| Getz, K | 1 |
| Juhascik, M | 2 |
| McElhinny, M | 1 |
| Dudley, S | 1 |
| Rahman, S | 1 |
| Trussell, A | 1 |
| Pearson, SA | 1 |
| Buckley, NA | 1 |
| Karanges, EA | 1 |
| Cairns, R | 1 |
| Litchfield, M | 1 |
| Todd, A | 1 |
| Gisev, N | 1 |
| Shearer, D | 1 |
| Young, S | 1 |
| Fairbairn, N | 1 |
| Brar, R | 1 |
| O'Donnell, J | 2 |
| Gladden, RM | 1 |
| Kariisa, M | 2 |
| Mattson, CL | 2 |
| Choi, NG | 1 |
| Choi, BY | 1 |
| DiNitto, DM | 1 |
| Marti, CN | 1 |
| Baker, SD | 1 |
| Trecki, J | 1 |
| Gerona, RR | 1 |
| Ellison, R | 1 |
| Thomas, C | 1 |
| Mileusnic-Polchan, D | 1 |
| Irvine, MA | 2 |
| Oller, D | 1 |
| Boggis, J | 1 |
| Bishop, B | 1 |
| Coombs, D | 2 |
| Wheeler, E | 1 |
| Doe-Simkins, M | 1 |
| Walley, AY | 1 |
| Bratberg, J | 1 |
| Green, TC | 2 |
| Britch, SC | 1 |
| Walsh, SL | 1 |
| King, E | 1 |
| Marchetti, L | 1 |
| Weidele, H | 1 |
| Wolanski, J | 1 |
| Shrestha, N | 1 |
| St John, K | 1 |
| Taylor, M | 1 |
| Pradhan, A | 1 |
| Ogando, YM | 1 |
| Shaya, F | 1 |
| Dale, O | 1 |
| Napoletano, S | 1 |
| Basile, G | 1 |
| Lo Faro, AF | 1 |
| Negro, F | 1 |
| Weitzman, ER | 1 |
| Kossowsky, J | 1 |
| Blakemore, LM | 1 |
| Cox, R | 1 |
| Dowling, DJ | 1 |
| Levy, O | 1 |
| Needles, EW | 1 |
| Levy, S | 1 |
| Coffin, PO | 1 |
| Maya, S | 1 |
| Kahn, JG | 1 |
| Rivera, AV | 1 |
| Nolan, ML | 1 |
| Paone, D | 1 |
| Carrillo, SA | 1 |
| Braunstein, SL | 1 |
| Strickland, JC | 1 |
| Marks, KR | 1 |
| Smith, KE | 1 |
| Ellis, JD | 1 |
| Hobelmann, JG | 1 |
| Huhn, AS | 1 |
| Calello, DP | 1 |
| Aldy, K | 3 |
| Jefri, M | 1 |
| Nguyen, TT | 1 |
| Krotulski, A | 2 |
| Logan, B | 2 |
| Brent, J | 3 |
| Wax, P | 3 |
| Walton, S | 1 |
| Manini, AF | 3 |
| Mann, J | 1 |
| Samieegohar, M | 1 |
| Chaturbedi, A | 1 |
| Zirkle, J | 1 |
| Han, X | 1 |
| Ahmadi, SF | 1 |
| Eshleman, A | 1 |
| Wolfrum, K | 1 |
| Swanson, T | 1 |
| Bloom, S | 1 |
| Dahan, A | 2 |
| Olofsen, E | 1 |
| Florian, J | 1 |
| Strauss, DG | 1 |
| Li, Z | 1 |
| Shin, SS | 1 |
| LaForge, K | 1 |
| Stack, E | 1 |
| Pope, J | 1 |
| Leichtling, G | 1 |
| Larsen, JE | 1 |
| Leahy, JM | 1 |
| Seaman, A | 1 |
| Hoover, D | 1 |
| Chisholm, L | 1 |
| Blazes, C | 1 |
| Baker, R | 1 |
| Byers, M | 1 |
| Branson, K | 1 |
| Korthuis, PT | 1 |
| Rezaeiahari, M | 1 |
| Fairman, BJ | 1 |
| Skurtveit, S | 1 |
| Odsbu, I | 1 |
| Gjersing, L | 1 |
| Handal, M | 1 |
| Lid, TG | 1 |
| Clausen, T | 1 |
| Hamina, A | 1 |
| Filteau, MR | 1 |
| Green, B | 1 |
| Kim, F | 1 |
| McBride, KA | 1 |
| Gooley, B | 1 |
| Weston, B | 1 |
| Colella, MR | 1 |
| Farkas, A | 1 |
| Disney, A | 1 |
| Olson, KM | 1 |
| Shafer, AM | 1 |
| Moore, SC | 1 |
| Anand, JP | 1 |
| Traynor, JR | 1 |
| Husbands, SM | 1 |
| Abadie, R | 3 |
| Cano, M | 3 |
| Habecker, P | 3 |
| Gelpí-Acosta, C | 3 |
| Luba, R | 3 |
| Jones, J | 3 |
| Choi, CJ | 3 |
| Comer, S | 3 |
| Peeters, LEJ | 3 |
| Vleut, IT | 3 |
| Tan, GE | 3 |
| Croes, EA | 3 |
| Bethlehem, C | 3 |
| Marchette, RCN | 1 |
| Carlson, ER | 1 |
| Frye, EV | 1 |
| Hastings, LE | 1 |
| Vendruscolo, JCM | 1 |
| Mejias-Torres, G | 1 |
| Lewis, SJ | 1 |
| Hampson, A | 1 |
| Volkow, ND | 1 |
| Vendruscolo, LF | 1 |
| Koob, GF | 1 |
| Stopka, TJ | 2 |
| Larochelle, MR | 1 |
| Li, X | 1 |
| Bernson, D | 1 |
| Li, W | 1 |
| Ackerson, LK | 1 |
| Bayly, R | 1 |
| Dammann, O | 1 |
| Bauer, C | 1 |
| Tilhou, AS | 1 |
| Zaborek, J | 1 |
| Baltes, A | 1 |
| Salisbury-Afshar, E | 1 |
| Malicki, J | 1 |
| Brown, R | 1 |
| Kline, A | 2 |
| Williams, JM | 2 |
| Steinberg, ML | 1 |
| Mattern, D | 2 |
| Chesin, M | 1 |
| Borys, S | 2 |
| Chaguturu, V | 1 |
| Love, JS | 1 |
| Levine, M | 1 |
| Krotulski, AJ | 1 |
| Logan, BK | 1 |
| Vargas-Torres, C | 1 |
| Walton, SE | 1 |
| Amaducci, A | 2 |
| Calello, D | 1 |
| Hendrickson, R | 1 |
| Hughes, A | 1 |
| Kurt, A | 1 |
| Judge, B | 1 |
| Pizon, A | 1 |
| Schwarz, E | 1 |
| Shulman, J | 1 |
| Wiegan, T | 1 |
| Allen, C | 1 |
| Arredondo, C | 1 |
| Dunham, R | 1 |
| Fishman, M | 1 |
| Lev, L | 1 |
| Mace, S | 1 |
| Parks, J | 1 |
| Rosa, D | 1 |
| Shoyinka, S | 1 |
| White, D | 1 |
| Williams, A | 1 |
| Ruhter, L | 1 |
| Silverstein, S | 1 |
| Bedard, ML | 1 |
| Nowlan, AC | 1 |
| Martin Del Campo, Z | 1 |
| Miller, C | 1 |
| Dasgupta, N | 1 |
| McElligott, ZA | 1 |
| Jeffery, MM | 1 |
| Stevens, M | 1 |
| D'Onofrio, G | 1 |
| Melnick, ER | 1 |
| Salazar, A | 1 |
| Moreno-Pulido, S | 1 |
| Prego-Meleiro, P | 1 |
| Henares-Montiel, J | 1 |
| Pulido, J | 1 |
| Donat, M | 1 |
| Sotres-Fernandez, G | 1 |
| Sordo, L | 1 |
| Kumar, S | 1 |
| Goldberger, BA | 1 |
| Santelices, C | 1 |
| Matsumoto, A | 1 |
| Boulad, M | 1 |
| Eubanks, LM | 1 |
| Pholcharee, T | 1 |
| Oyen, D | 1 |
| Natori, Y | 1 |
| Zhou, B | 1 |
| Wilson, IA | 1 |
| Janda, KD | 1 |
| Campleman, SL | 1 |
| Li, S | 1 |
| Meyn, A | 1 |
| Abston, S | 1 |
| Culbreth, RE | 1 |
| Friedman, J | 1 |
| Shover, CL | 1 |
| Savinkina, A | 1 |
| Jurecka, C | 1 |
| Gonsalves, G | 1 |
| Barocas, JA | 1 |
| Maguire, DR | 1 |
| France, CP | 1 |
| Hartmann, GE | 1 |
| Sethi, R | 1 |
| McGowan, R | 1 |
| Hammond, K | 1 |
| Davison, C | 1 |
| Gilbert, M | 1 |
| Rosenblum, D | 1 |
| Unick, J | 1 |
| Ciccarone, D | 2 |
| Moe, J | 1 |
| Godwin, J | 1 |
| Purssell, R | 1 |
| O'Sullivan, F | 1 |
| Hau, JP | 1 |
| Purssell, E | 1 |
| Curran, J | 1 |
| Doyle-Waters, MM | 1 |
| Brasher, PMA | 1 |
| Buxton, JA | 2 |
| Hohl, CM | 1 |
| Switzer, AR | 1 |
| Beland, B | 1 |
| Sarna, JR | 1 |
| Walzak, A | 1 |
| Pfeffer, G | 1 |
| Meier, A | 1 |
| Moore, SK | 1 |
| Saunders, EC | 1 |
| McLeman, B | 1 |
| Metcalf, SA | 1 |
| Auty, S | 1 |
| Walsh, O | 1 |
| Marsch, LA | 1 |
| Chatterton, CN | 1 |
| Handy, RP | 1 |
| Shoemaker, GK | 1 |
| Scott-Ham, M | 1 |
| Carroll, JJ | 1 |
| Rich, JD | 1 |
| Dinicu, AI | 1 |
| Chaudhari, A | 1 |
| Kayyal, S | 1 |
| Furr-Holden, D | 1 |
| Milam, AJ | 1 |
| Wang, L | 1 |
| Sadler, R | 1 |
| Ivsins, A | 1 |
| Boyd, J | 1 |
| Mayer, S | 1 |
| Collins, A | 1 |
| Sutherland, C | 1 |
| Kerr, T | 1 |
| McNeil, R | 1 |
| Stanton, JD | 1 |
| Whitley, P | 1 |
| LaRue, L | 1 |
| Bundy, WL | 1 |
| Dawson, E | 1 |
| Huskey, A | 1 |
| Althoff, KN | 1 |
| Leifheit, KM | 1 |
| Park, JN | 1 |
| Chandran, A | 1 |
| Sherman, SG | 2 |
| Jacka, BP | 1 |
| Goldman, JE | 1 |
| Yedinak, JL | 1 |
| Bernstein, E | 1 |
| Hadland, SE | 1 |
| Biello, KB | 1 |
| Cooperman, N | 1 |
| Dooley-Budsock, P | 1 |
| Foglia, R | 1 |
| Kosten, TR | 1 |
| Petrakis, IL | 1 |
| Hodder, SL | 1 |
| Feinberg, J | 1 |
| Strathdee, SA | 1 |
| Shoptaw, S | 1 |
| Altice, FL | 1 |
| Ortenzio, L | 1 |
| Beyrer, C | 1 |
| Krausz, RM | 1 |
| Westenberg, JN | 1 |
| Ziafat, K | 1 |
| Pergolizzi, JV | 2 |
| Ann LeQuang, J | 2 |
| Raffa, RB | 2 |
| Webster, LR | 1 |
| Vortsman, E | 1 |
| Crystal, S | 1 |
| Nowels, M | 1 |
| Olfson, M | 1 |
| Samples, H | 1 |
| Williams, AR | 1 |
| Treitler, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Rhode Island Prescription and Illicit Drug Study Responding to Fentanyl and Associated Harms[NCT04372238] | 509 participants (Anticipated) | Interventional | 2020-09-03 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
10 reviews available for fentanyl and Opiate Overdose
| Article | Year |
|---|---|
Estimating naloxone need in the USA across fentanyl, heroin, and prescription opioid epidemics: a modelling study.
Topics: Analgesics, Opioid; Drug Overdose; Fentanyl; Heroin; Humans; Naloxone; Narcotic Antagonists; Opiate | 2022 |
Treatment of opioid overdose: current approaches and recent advances.
Topics: Analgesics, Opioid; Drug Overdose; Drug-Related Side Effects and Adverse Reactions; Fentanyl; Humans | 2022 |
Pharmacokinetic considerations for community-based dosing of nasal naloxone in opioid overdose in adults.
Topics: Adult; Analgesics, Opioid; Drug Overdose; Fentanyl; Humans; Naloxone; Narcotic Antagonists; Opiate O | 2022 |
All Hands on Deck: We Need Multiple Approaches To Uncover the Neuroscience behind the Opioid Overdose Crisis.
Topics: Analgesics, Opioid; Drug Overdose; Fentanyl; Humans; Opiate Overdose; Opioid-Related Disorders; Unit | 2023 |
The Role of Non-Pharmaceutical Fentanyl-Contaminated Counterfeit Oxycodone in Increasing Opioid Overdoses: A Commentary Review.
Topics: Analgesics, Opioid; Drug Overdose; Fentanyl; Humans; Opiate Overdose; Opioid-Related Disorders; Oxyc | 2023 |
Naloxone dosing in the era of ultra-potent opioid overdoses: a systematic review.
Topics: Adult; Analgesics, Opioid; Child; Drug Overdose; Female; Fentanyl; Humans; Male; Naloxone; Narcotic | 2020 |
The opioid crisis and HIV in the USA: deadly synergies.
Topics: Adolescent; Adult; Analgesics, Opioid; Black or African American; Case-Control Studies; Disease Outb | 2021 |
The opioid overdose crisis as a global health challenge.
Topics: Analgesics, Opioid; Fentanyl; Global Health; Humans; Opiate Overdose; Prevalence | 2021 |
The rise of illicit fentanyls, stimulants and the fourth wave of the opioid overdose crisis.
Topics: Analgesics, Opioid; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Comorbidi | 2021 |
Overdoses due to fentanyl and its analogues (F/FAs) push naloxone to the limit.
Topics: Diaphragm; Dose-Response Relationship, Drug; Fentanyl; Heroin; Humans; Laryngismus; Muscle Rigidity; | 2021 |
1 trial available for fentanyl and Opiate Overdose
| Article | Year |
|---|---|
A randomized clinical trial of a theory-based fentanyl overdose education and fentanyl test strip distribution intervention to reduce rates of opioid overdose: study protocol for a randomized controlled trial.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Fentanyl; Humans; Middle Aged; North America; Opiate Ov | 2020 |
58 other studies available for fentanyl and Opiate Overdose
| Article | Year |
|---|---|
Sodium chloride injection to treat opioid overdose; Does it work? A preclinical study.
Topics: Animals; Dose-Response Relationship, Drug; Fentanyl; Injections, Intravenous; Male; Morphine; Naloxo | 2021 |
Toxicological and pharmacologic sex differences in unintentional or undetermined opioid overdose death.
Topics: Adult; Analgesics, Opioid; Drug Overdose; Female; Fentanyl; Humans; Male; Opiate Overdose; Retrospec | 2021 |
Fentanyl causes naloxone-resistant vocal cord closure: A platform for testing opioid overdose treatments.
Topics: Analgesics, Opioid; Animals; Drug Overdose; Fentanyl; Naloxone; Narcotic Antagonists; Opiate Overdos | 2021 |
Lay knowledge and practices of methamphetamine use to manage opioid-related overdose risks.
Topics: Adult; Analgesics, Opioid; Drug Overdose; Female; Fentanyl; Humans; Methamphetamine; Opiate Overdose | 2022 |
Trends in transdermal fentanyl utilisation and fatal fentanyl overdose across Australia (2003-2015).
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Drug Overdose; Female; Fentanyl; Humans; Male; O | 2022 |
Challenges with buprenorphine inductions in the context of the fentanyl overdose crisis: A case series.
Topics: Analgesics, Opioid; Buprenorphine; Buprenorphine, Naloxone Drug Combination; Fentanyl; Humans; Nalox | 2022 |
Using death scene and toxicology evidence to define involvement of heroin, pharmaceutical morphine, illicitly manufactured fentanyl and pharmaceutical fentanyl in opioid overdose deaths, 38 states and the District of Columbia, January 2018-December 2019.
Topics: Analgesics, Opioid; District of Columbia; Drug Overdose; Fentanyl; Heroin; Humans; Illicit Drugs; Mo | 2022 |
Heroin and fentanyl overdose deaths among cases age 50+ in the National Poison Data System, 2015-2020.
Topics: Aged; Analgesics, Opioid; COVID-19; Drug Overdose; Fentanyl; Heroin; Humans; Middle Aged; Opiate Ove | 2022 |
Notes from the Field: Increased Incidence of Fentanyl-Related Deaths Involving Para-fluorofentanyl or Metonitazene - Knox County, Tennessee, November 2020-August 2021.
Topics: Benzimidazoles; Fentanyl; Humans; Illicit Drugs; Opiate Overdose; Piperidines; Tennessee | 2022 |
Insights from biosurveillance: non-fatal opioid overdoses in Rhode Island 2019-21.
Topics: Analgesics, Opioid; Biosurveillance; Drug Overdose; Fentanyl; Humans; Opiate Overdose; Rhode Island | 2022 |
Impact of the naloxone standing order on trends in opioid fatal overdose: an ecological analysis.
Topics: Analgesics, Opioid; Drug Overdose; Female; Fentanyl; Humans; Naloxone; Narcotic Antagonists; Opiate | 2022 |
New Psychoactive Substances and receding COVID-19 pandemic: really going back to "normal"?
Topics: Analgesics, Opioid; COVID-19; Ecosystem; Fentanyl; Humans; Opiate Overdose; Pandemics; SARS-CoV-2 | 2022 |
Acceptability of a Fentanyl Vaccine to Prevent Opioid Overdose and Need for Personalized Decision-Making.
Topics: Adult; Analgesics, Opioid; COVID-19; Drug Overdose; Female; Fentanyl; Humans; Male; Opiate Overdose; | 2022 |
Modeling of overdose and naloxone distribution in the setting of fentanyl compared to heroin.
Topics: Analgesics, Opioid; Drug Overdose; Fentanyl; Heroin; Humans; Naloxone; Narcotic Antagonists; Opiate | 2022 |
Gaps in naloxone ownership among people who inject drugs during the fentanyl wave of the opioid overdose epidemic in New York City, 2018.
Topics: Analgesics, Opioid; Drug Overdose; Drug Users; Fentanyl; Humans; Naloxone; New York City; Opiate Ove | 2022 |
Patient perceptions of higher-dose naloxone nasal spray for opioid overdose.
Topics: Analgesics, Opioid; Drug Overdose; Fentanyl; Humans; Naloxone; Narcotic Antagonists; Nasal Sprays; O | 2022 |
Identification of a novel opioid,
Topics: Adult; Alprazolam; Analgesics, Opioid; Benzimidazoles; Cocaine; Codeine; Drug Overdose; Fentanyl; He | 2022 |
Development of a Translational Model to Assess the Impact of Opioid Overdose and Naloxone Dosing on Respiratory Depression and Cardiac Arrest.
Topics: Analgesics, Opioid; Drug Overdose; Fentanyl; Heart Arrest; Humans; Naloxone; Narcotic Antagonists; O | 2022 |
"It wasn't here, and now it is. It's everywhere": fentanyl's rising presence in Oregon's drug supply.
Topics: Analgesics, Opioid; Drug Overdose; Fentanyl; Humans; Illicit Drugs; Opiate Overdose; Opioid-Related | 2022 |
Impact of COVID-19 on the characteristics of opioid overdose deaths in Arkansas.
Topics: Analgesics, Opioid; Arkansas; COVID-19; Drug Overdose; Fentanyl; Humans; Methadone; Methamphetamine; | 2022 |
Individuals Dying of Overdoses Related to Pharmaceutical Opioids Differ from Individuals Dying of Overdoses Related to Other Substances: A Population-Based Register Study.
Topics: Aged; Analgesics, Opioid; Chronic Pain; Drug Overdose; Female; Fentanyl; Humans; Opiate Overdose; Ph | 2022 |
'It's the same thing as giving them CPR training': rural first responders' perspectives on naloxone.
Topics: Analgesics, Opioid; Cardiopulmonary Resuscitation; Drug Overdose; Emergency Responders; Fentanyl; Hu | 2022 |
Outcomes of law enforcement officer administered naloxone.
Topics: Analgesics, Opioid; Drug Overdose; Fentanyl; Humans; Naloxone; Narcotic Antagonists; Opiate Overdose | 2022 |
Opioid Antagonists from the Orvinol Series as Potential Reversal Agents for Opioid Overdose.
Topics: Analgesics, Opioid; Fentanyl; Humans; Naloxone; Narcotic Antagonists; Opiate Overdose; Receptors, Op | 2022 |
Substance use, injection risk behaviors, and fentanyl-related overdose risk among a sample of PWID post-Hurricane Maria.
Topics: Cyclonic Storms; Drug Overdose; Fentanyl; Humans; Opiate Overdose; Opioid-Related Disorders; Risk-Ta | 2022 |
Substance use, injection risk behaviors, and fentanyl-related overdose risk among a sample of PWID post-Hurricane Maria.
Topics: Cyclonic Storms; Drug Overdose; Fentanyl; Humans; Opiate Overdose; Opioid-Related Disorders; Risk-Ta | 2022 |
Substance use, injection risk behaviors, and fentanyl-related overdose risk among a sample of PWID post-Hurricane Maria.
Topics: Cyclonic Storms; Drug Overdose; Fentanyl; Humans; Opiate Overdose; Opioid-Related Disorders; Risk-Ta | 2022 |
Substance use, injection risk behaviors, and fentanyl-related overdose risk among a sample of PWID post-Hurricane Maria.
Topics: Cyclonic Storms; Drug Overdose; Fentanyl; Humans; Opiate Overdose; Opioid-Related Disorders; Risk-Ta | 2022 |
Substance use, injection risk behaviors, and fentanyl-related overdose risk among a sample of PWID post-Hurricane Maria.
Topics: Cyclonic Storms; Drug Overdose; Fentanyl; Humans; Opiate Overdose; Opioid-Related Disorders; Risk-Ta | 2022 |
Substance use, injection risk behaviors, and fentanyl-related overdose risk among a sample of PWID post-Hurricane Maria.
Topics: Cyclonic Storms; Drug Overdose; Fentanyl; Humans; Opiate Overdose; Opioid-Related Disorders; Risk-Ta | 2022 |
Substance use, injection risk behaviors, and fentanyl-related overdose risk among a sample of PWID post-Hurricane Maria.
Topics: Cyclonic Storms; Drug Overdose; Fentanyl; Humans; Opiate Overdose; Opioid-Related Disorders; Risk-Ta | 2022 |
Substance use, injection risk behaviors, and fentanyl-related overdose risk among a sample of PWID post-Hurricane Maria.
Topics: Cyclonic Storms; Drug Overdose; Fentanyl; Humans; Opiate Overdose; Opioid-Related Disorders; Risk-Ta | 2022 |
Substance use, injection risk behaviors, and fentanyl-related overdose risk among a sample of PWID post-Hurricane Maria.
Topics: Cyclonic Storms; Drug Overdose; Fentanyl; Humans; Opiate Overdose; Opioid-Related Disorders; Risk-Ta | 2022 |
Fentanyl withdrawal: Understanding symptom severity and exploring the role of body mass index on withdrawal symptoms and clearance.
Topics: Analgesics, Opioid; Animals; Body Mass Index; Cattle; Female; Fentanyl; Morphine; Narcotic Antagonis | 2023 |
Fentanyl withdrawal: Understanding symptom severity and exploring the role of body mass index on withdrawal symptoms and clearance.
Topics: Analgesics, Opioid; Animals; Body Mass Index; Cattle; Female; Fentanyl; Morphine; Narcotic Antagonis | 2023 |
Fentanyl withdrawal: Understanding symptom severity and exploring the role of body mass index on withdrawal symptoms and clearance.
Topics: Analgesics, Opioid; Animals; Body Mass Index; Cattle; Female; Fentanyl; Morphine; Narcotic Antagonis | 2023 |
Fentanyl withdrawal: Understanding symptom severity and exploring the role of body mass index on withdrawal symptoms and clearance.
Topics: Analgesics, Opioid; Animals; Body Mass Index; Cattle; Female; Fentanyl; Morphine; Narcotic Antagonis | 2023 |
Case report on postmortem fentanyl measurement after overdose with more than 67 fentanyl patches.
Topics: Adult; Autopsy; Cocaine; Drug Overdose; Fentanyl; Humans; Male; Opiate Overdose; Young Adult | 2022 |
Case report on postmortem fentanyl measurement after overdose with more than 67 fentanyl patches.
Topics: Adult; Autopsy; Cocaine; Drug Overdose; Fentanyl; Humans; Male; Opiate Overdose; Young Adult | 2022 |
Case report on postmortem fentanyl measurement after overdose with more than 67 fentanyl patches.
Topics: Adult; Autopsy; Cocaine; Drug Overdose; Fentanyl; Humans; Male; Opiate Overdose; Young Adult | 2022 |
Case report on postmortem fentanyl measurement after overdose with more than 67 fentanyl patches.
Topics: Adult; Autopsy; Cocaine; Drug Overdose; Fentanyl; Humans; Male; Opiate Overdose; Young Adult | 2022 |
Heroin- and Fentanyl-Induced Respiratory Depression in a Rat Plethysmography Model: Potency, Tolerance, and Sex Differences.
Topics: Analgesics, Opioid; Animals; Female; Fentanyl; Heroin; Male; Opiate Overdose; Plethysmography; Rats; | 2023 |
Opioid-related mortality: Dynamic temporal and spatial trends by drug type and demographic subpopulations, Massachusetts, 2005-2021.
Topics: Adult; Age Distribution; Analgesics, Opioid; Drug Overdose; Fentanyl; Humans; Male; Massachusetts; M | 2023 |
Differences in drug use behaviors that impact overdose risk among individuals who do and do not use fentanyl test strips for drug checking.
Topics: Analgesics, Opioid; Drug Overdose; Fentanyl; Harm Reduction; Humans; Opiate Overdose; Substance-Rela | 2023 |
Predictors of opioid overdose during the COVID-19 pandemic: The role of relapse, treatment access and nonprescribed buprenorphine/naloxone.
Topics: Analgesics, Opioid; Buprenorphine, Naloxone Drug Combination; COVID-19; Drug Overdose; Fentanyl; Hum | 2023 |
Opioid overdoses involving xylazine in emergency department patients: a multicenter study.
Topics: Adult; Analgesics, Opioid; Coma; Drug Overdose; Emergency Service, Hospital; Fentanyl; Humans; Opiat | 2023 |
Guidance for Handling the Increasing Prevalence of Drugs Adulterated or Laced With Fentanyl.
Topics: Analgesics, Opioid; Drug Overdose; Fentanyl; Humans; Opiate Overdose; Opioid-Related Disorders; Phar | 2023 |
Attitudes and experiences with fentanyl contamination of methamphetamine: exploring self-reports and urine toxicology among persons who use methamphetamine and other drugs.
Topics: Analgesics, Opioid; Drug Overdose; Female; Fentanyl; Heroin; Humans; Male; Methamphetamine; Opiate O | 2023 |
Fentanyl-Associated Overdose Deaths Outside the Hospital.
Topics: Analgesics, Opioid; Drug Overdose; Fentanyl; Hospitals; Humans; Opiate Overdose | 2023 |
Correlation Between Opioid Drug Prescription and Opioid-Related Mortality in Spain as a Surveillance Tool: Ecological Study.
Topics: Analgesics, Opioid; Drug Prescriptions; Fentanyl; Humans; Opiate Overdose; Opioid-Related Disorders; | 2023 |
Illicitly Manufactured Fentanyl-Involved Overdose Deaths with Detected Xylazine - United States, January 2019-June 2022.
Topics: District of Columbia; Drug Overdose; Fentanyl; Humans; Opiate Overdose; United States; Xylazine | 2023 |
Evaluating Technologies to Identify Fentanyl and Adulterants in Street Drug Paraphernalia: Qualitative Perspectives of Service Providers and Their Clientele.
Topics: Analgesics, Opioid; Drug Overdose; Fentanyl; Harm Reduction; Humans; Illicit Drugs; Opiate Overdose; | 2023 |
An Engineered Human-Antibody Fragment with Fentanyl Pan-Specificity That Reverses Carfentanil-Induced Respiratory Depression.
Topics: Analgesics, Opioid; Drug Overdose; Fentanyl; Humans; Immunoglobulin Fragments; Opiate Overdose; Resp | 2023 |
Naloxone Use in Novel Potent Opioid and Fentanyl Overdoses in Emergency Department Patients.
Topics: Adult; Analgesics, Opioid; Cohort Studies; Disease Progression; Drug Overdose; Emergency Service, Ho | 2023 |
Charting the fourth wave: Geographic, temporal, race/ethnicity and demographic trends in polysubstance fentanyl overdose deaths in the United States, 2010-2021.
Topics: Analgesics, Opioid; Central Nervous System Stimulants; Cocaine; Drug Overdose; Ethnicity; Fentanyl; | 2023 |
Mortality, incarceration and cost implications of fentanyl felonization laws: A modeling study.
Topics: Analgesics, Opioid; Drug Overdose; Fentanyl; Humans; Opiate Overdose; Opioid-Related Disorders; Unit | 2023 |
Daily methocinnamox treatment dose-dependently attenuates fentanyl self-administration in rhesus monkeys.
Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Female; Fentanyl; Macaca mulatta; Mal | 2024 |
The role of mathematical modelling in aiding public health policy decision-making: A case study of the BC opioid overdose emergency.
Topics: Analgesics, Opioid; British Columbia; Drug Overdose; Fentanyl; Health Policy; Humans; Naloxone; Opia | 2021 |
The Rapidly Changing US Illicit Drug Market and the Potential for an Improved Early Warning System: Evidence from Ohio Drug Crime Labs.
Topics: Analgesics, Opioid; Crime; Drug Overdose; Female; Fentanyl; Forensic Medicine; Heroin; Humans; Illic | 2020 |
Fentanyl Overdose Causing Hippocampal Ischaemia Followed by Delayed Leukoencephalopathy.
Topics: Analgesics, Opioid; Brain Ischemia; Disease Progression; Fentanyl; Hippocampus; Humans; Hypoventilat | 2020 |
Understanding the increase in opioid overdoses in New Hampshire: A rapid epidemiologic assessment.
Topics: Adolescent; Adult; Analgesics, Opioid; Female; Fentanyl; Harm Reduction; Heroin; Humans; Male; Needl | 2020 |
The distribution and redistribution of carfentanil in post mortem samples.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Female; Fentanyl; Forensic Toxicology; Humans; Male; Mi | 2020 |
The protective effect of trusted dealers against opioid overdose in the U.S.
Topics: Adult; Analgesics, Opioid; Drug Overdose; Female; Fentanyl; Harm Reduction; Humans; Male; Middle Age | 2020 |
Diffuse subcortical white matter injury and bilateral basal ganglia neuronal loss after acute opioid overdose.
Topics: Brain; Fentanyl; Humans; Leukoencephalopathies; Male; Narcotics; Neurons; Opiate Overdose; Oxycodone | 2020 |
African Americans now outpace whites in opioid-involved overdose deaths: a comparison of temporal trends from 1999 to 2018.
Topics: Analgesics, Opioid; Black or African American; Drug Overdose; Fentanyl; Humans; Opiate Overdose; Uni | 2021 |
Barriers and facilitators to a novel low-barrier hydromorphone distribution program in Vancouver, Canada: a qualitative study.
Topics: Analgesics, Opioid; Canada; Drug Contamination; Drug Overdose; Female; Fentanyl; Humans; Hydromorpho | 2020 |
Fentanyl analog positivity among near-real-time urine drug test results in patients seeking health care.
Topics: Adult; Aged; Analgesics, Opioid; Chromatography, Liquid; Cross-Sectional Studies; Female; Fentanyl; | 2020 |
Opioid-related overdose mortality in the era of fentanyl: Monitoring a shifting epidemic by person, place, and time.
Topics: Adult; Aged; Analgesics, Opioid; Centers for Disease Control and Prevention, U.S.; Databases, Factua | 2020 |
Opioid overdose in the age of fentanyl: Risk factor differences among subpopulations of overdose survivors.
Topics: Analgesics, Opioid; Cross-Sectional Studies; Drug Overdose; Fentanyl; Humans; New Jersey; Opiate Ove | 2021 |
The Hidden Epidemic of Opioid Overdoses During the Coronavirus Disease 2019 Pandemic.
Topics: Attitude of Health Personnel; Comorbidity; COVID-19; Fentanyl; Humans; Opiate Overdose; Opioid Epide | 2021 |
Wooden Chest syndrome: The atypical pharmacology of fentanyl overdose.
Topics: Diaphragm; Fentanyl; Heroin; Humans; Laryngismus; Muscle Rigidity; Opiate Overdose; Syndrome; Thorac | 2021 |
Medically treated opioid overdoses among New Jersey Medicaid beneficiaries: Rapid growth and complex comorbidity amid growing fentanyl penetration.
Topics: Adolescent; Adult; Analgesics, Opioid; Child; Comorbidity; Depressive Disorder, Major; Drug Overdose | 2021 |