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fentanyl and Neuroleptic Malignant Syndrome

fentanyl has been researched along with Neuroleptic Malignant Syndrome in 3 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Neuroleptic Malignant Syndrome: A potentially fatal syndrome associated primarily with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS) which are in turn associated with dopaminergic receptor blockade (see RECEPTORS, DOPAMINE) in the BASAL GANGLIA and HYPOTHALAMUS, and sympathetic dysregulation. Clinical features include diffuse MUSCLE RIGIDITY; TREMOR; high FEVER; diaphoresis; labile blood pressure; cognitive dysfunction; and autonomic disturbances. Serum CPK level elevation and a leukocytosis may also be present. (From Adams et al., Principles of Neurology, 6th ed, p1199; Psychiatr Serv 1998 Sep;49(9):1163-72)

Research Excerpts

ExcerptRelevanceReference
"This case report describes a terminally ill patient with cancer with severe hypophosphataemia, hypocalcemia, and hypomagnesemia who developed neuroleptic malignant syndrome after administration of a combination of haloperidol and fentanyl."7.72Neuroleptic malignant syndrome after haloperidol and fentanyl infusion in a patient with cancer with severe mineral imbalance. ( Inoue, S; Morita, T; Nagayama, K; Shishido, H; Tei, Y, 2004)
"This case report describes a terminally ill patient with cancer with severe hypophosphataemia, hypocalcemia, and hypomagnesemia who developed neuroleptic malignant syndrome after administration of a combination of haloperidol and fentanyl."3.72Neuroleptic malignant syndrome after haloperidol and fentanyl infusion in a patient with cancer with severe mineral imbalance. ( Inoue, S; Morita, T; Nagayama, K; Shishido, H; Tei, Y, 2004)
"Thus, physician should consider catatonia when treating neuroleptic malignant like syndrome."1.36[Case with difficulty in differentiating between transient neuroleptic malignant syndrome and catatonia after neuroleptic analgesia]. ( Miyazaki, M; Yanagawa, Y, 2010)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Whyte, CJ1
Rosini, JM1
Yanagawa, Y1
Miyazaki, M1
Morita, T1
Shishido, H1
Tei, Y1
Inoue, S1
Nagayama, K1

Other Studies

3 other studies available for fentanyl and Neuroleptic Malignant Syndrome

ArticleYear
Dantrolene for Treatment of Suspected Neuroleptic Malignant Syndrome.
    Journal of emergency nursing, 2018, Volume: 44, Issue:2

    Topics: Analgesics, Opioid; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Dantrolene; Diagnosis, D

2018
[Case with difficulty in differentiating between transient neuroleptic malignant syndrome and catatonia after neuroleptic analgesia].
    Masui. The Japanese journal of anesthesiology, 2010, Volume: 59, Issue:2

    Topics: Adolescent; Analgesia; Anesthesia, General; Catatonia; Diagnosis, Differential; Diazepam; Droperidol

2010
Neuroleptic malignant syndrome after haloperidol and fentanyl infusion in a patient with cancer with severe mineral imbalance.
    Journal of palliative medicine, 2004, Volume: 7, Issue:6

    Topics: Aged; Analgesics, Opioid; Dopamine Antagonists; Drug Therapy, Combination; Esophageal Neoplasms; Fen

2004