Page last updated: 2024-10-27

fentanyl and Nervous System Diseases

fentanyl has been researched along with Nervous System Diseases in 15 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Nervous System Diseases: Diseases of the central and peripheral nervous system. This includes disorders of the brain, spinal cord, cranial nerves, peripheral nerves, nerve roots, autonomic nervous system, neuromuscular junction, and muscle.

Research Excerpts

ExcerptRelevanceReference
"Of 200 consecutive breast cancer patients, 191 received the full package."2.75Multimodal prevention of pain, nausea and vomiting after breast cancer surgery. ( Callesen, T; Gärtner, R; Kehlet, H; Kroman, N, 2010)
"Asystolic cardiac arrest for 8 minutes was induced in 73 rats with a mixture of potassium chloride and esmolol."1.42Do different anesthesia regimes affect hippocampal apoptosis and neurologic deficits in a rodent cardiac arrest model? ( Bendel, S; Grandgirard, D; Haenggi, M; Jakob, SM; Leib, SL; Pereira, A; Putzu, A; Schlickeiser, J; Springe, D; Takala, J, 2015)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19904 (26.67)18.7374
1990's4 (26.67)18.2507
2000's4 (26.67)29.6817
2010's3 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bendel, S1
Springe, D1
Pereira, A1
Grandgirard, D1
Leib, SL1
Putzu, A1
Schlickeiser, J1
Jakob, SM1
Takala, J1
Haenggi, M1
Lin, N1
Han, R1
Zhou, J1
Gelb, AW1
Gärtner, R1
Kroman, N1
Callesen, T1
Kehlet, H1
Stevens, B1
McGrath, P1
Gibbins, S1
Beyene, J1
Breau, L1
Camfield, C1
Finley, A1
Franck, L1
Howlett, A1
McKeever, P1
O'Brien, K1
Ohlsson, A1
Yamada, J1
Mehrotra, R1
Chiaretti, A1
Genovese, O1
Antonelli, A1
Tortorolo, L1
Ruggiero, A1
Focarelli, B1
Di Rocco, C1
Hoffman, WE1
Thomas, C1
Albrecht, RF1
Werner, C1
Möllenberg, O1
Kochs, E1
Haberer, JP1
Malan, MD1
Crago, RR1
Stevens, CW1
Kajander, KC1
Bennett, GJ1
Seybold, VS1
Ellis, DJ1
Steward, DJ1
McPherson, RW1
Mahla, M1
Johnson, R1
Traystman, RJ1
Gemperle, M1
Holmes, CM1
Gibbs, JM1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized Triple-blind Placebo Controlled Trial of Influence of Morphine or Ketamine or Saline Applied During In-hospital Cardiopulmonary Resuscitation on Early Survival and Neurological Outcome[NCT04009759]Phase 1240 participants (Anticipated)Interventional2021-10-01Not yet recruiting
Combined General Anesthesia Plus Paravertebral Block Versus General Anesthesia Plus Opioid Analgesia for Breast Cancer Surgery: A Prospective Randomized Trial[NCT01904266]60 participants (Actual)Interventional2013-05-31Completed
Multimodal Pain Treatment for Breast Cancer Surgery - a Prospective Cohort Study[NCT04875559]236 participants (Actual)Observational [Patient Registry]2021-04-19Completed
Comparison of Three Different Pain and Anxiety Reducing Methods in Adult Patients Undergoing Bone Marrow Puncture[NCT00188227]Phase 4748 participants Interventional2001-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for fentanyl and Nervous System Diseases

ArticleYear
Neuroleptanalgesia. 1.
    The New Zealand medical journal, 1967, Volume: 66, Issue:420

    Topics: Analgesics; Benperidol; Fentanyl; Haloperidol; Humans; Nervous System Diseases; Neuroleptanalgesia;

1967

Trials

3 trials available for fentanyl and Nervous System Diseases

ArticleYear
Mild Sedation Exacerbates or Unmasks Focal Neurologic Dysfunction in Neurosurgical Patients with Supratentorial Brain Mass Lesions in a Drug-specific Manner.
    Anesthesiology, 2016, Volume: 124, Issue:3

    Topics: Adult; Dexmedetomidine; Female; Fentanyl; Follow-Up Studies; Humans; Hypnotics and Sedatives; Male;

2016
Multimodal prevention of pain, nausea and vomiting after breast cancer surgery.
    Minerva anestesiologica, 2010, Volume: 76, Issue:10

    Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthesia, Intra

2010
Multimodal prevention of pain, nausea and vomiting after breast cancer surgery.
    Minerva anestesiologica, 2010, Volume: 76, Issue:10

    Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthesia, Intra

2010
Multimodal prevention of pain, nausea and vomiting after breast cancer surgery.
    Minerva anestesiologica, 2010, Volume: 76, Issue:10

    Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthesia, Intra

2010
Multimodal prevention of pain, nausea and vomiting after breast cancer surgery.
    Minerva anestesiologica, 2010, Volume: 76, Issue:10

    Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthesia, Intra

2010
Patient-controlled analgesia with fentanil and midazolam in children with postoperative neurosurgical pain.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2008, Volume: 24, Issue:1

    Topics: Adolescent; Analgesia, Patient-Controlled; Anesthetics, Intravenous; Blood Pressure; Child; Female;

2008

Other Studies

11 other studies available for fentanyl and Nervous System Diseases

ArticleYear
Do different anesthesia regimes affect hippocampal apoptosis and neurologic deficits in a rodent cardiac arrest model?
    BMC anesthesiology, 2015, Jan-15, Volume: 15

    Topics: Anesthetics; Animals; Apoptosis; Fentanyl; Heart Arrest; Hippocampus; Ketamine; Male; Medetomidine;

2015
Procedural pain in newborns at risk for neurologic impairment.
    Pain, 2003, Volume: 105, Issue:1-2

    Topics: Analgesics, Opioid; Cohort Studies; Diagnostic Tests, Routine; Drug Administration Schedule; Fentany

2003
General anesthesia for a patient with alternating hemiplegia of childhood.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2005, Volume: 52, Issue:10

    Topics: Abortion, Induced; Adjuvants, Anesthesia; Adult; Anesthesia, General; Anesthetics, Intravenous; Fema

2005
The effect of halothane and isoflurane on neurologic outcome following incomplete cerebral ischemia in the rat.
    Anesthesia and analgesia, 1993, Volume: 76, Issue:2

    Topics: Anesthesia, Inhalation; Animals; Brain Ischemia; Catecholamines; Fentanyl; Halothane; Isoflurane; Ma

1993
Sevoflurane improves neurological outcome after incomplete cerebral ischaemia in rats.
    British journal of anaesthesia, 1995, Volume: 75, Issue:6

    Topics: Anesthetics; Animals; Blood Glucose; Blood Pressure; Carbon Dioxide; Ethers; Fentanyl; Ischemic Atta

1995
[Premedication and sedation complications during ophthalmic anesthesia].
    Journal francais d'ophtalmologie, 2000, Volume: 23, Issue:9

    Topics: Adjuvants, Anesthesia; Alfentanil; Analgesics, Opioid; Anesthesia; Anesthesia, Conduction; Anesthesi

2000
Anaesthetic considerations in idiopathic orthostatic hypotension and the Shy-Drager syndrome.
    Canadian Anaesthetists' Society journal, 1979, Volume: 26, Issue:4

    Topics: Adult; Anesthesia; Diazepam; Fecal Incontinence; Fentanyl; Humans; Hypotension, Orthostatic; Lidocai

1979
Bilateral and differential changes in spinal mu, delta and kappa opioid binding in rats with a painful, unilateral neuropathy.
    Pain, 1991, Volume: 46, Issue:3

    Topics: Analgesics; Animals; Autoradiography; Behavior, Animal; Benzeneacetamides; Enkephalin, D-Penicillami

1991
Fentanyl dosage is associated with reduced blood glucose in pediatric patients after hypothermic cardiopulmonary bypass.
    Anesthesiology, 1990, Volume: 72, Issue:5

    Topics: Adolescent; Cardiopulmonary Bypass; Child; Child, Preschool; Fentanyl; Heart Arrest, Induced; Heart

1990
Effects of enflurane, isoflurane, and nitrous oxide on somatosensory evoked potentials during fentanyl anesthesia.
    Anesthesiology, 1985, Volume: 62, Issue:5

    Topics: Anesthesia, General; Arm; Blood Pressure; Body Temperature; Enflurane; Evoked Potentials, Somatosens

1985
[Neuroleptoanalgesia].
    Aktuelle Probleme in der Chirurgie, 1970, Volume: 12

    Topics: Aged; Aging; Animals; Cardiac Surgical Procedures; Cardiovascular System; Catecholamines; Central Ne

1970