fentanyl has been researched along with Myocardial Ischemia in 32 studies
Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.
Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study compares remifentanil/propofol (remi/prop) with isoflurane/fentanyl (iso/fen) anesthesia to determine which provides the greater hemodynamic stability, lesser myocardial ischemia, and morbidity with better postoperative outcomes after carotid endarterectomy." | 9.10 | Hemodynamic stability, myocardial ischemia, and perioperative outcome after carotid surgery with remifentanil/propofol or isoflurane/fentanyl anesthesia. ( Baker, WH; Jellish, WS; Louie, EK; Sheikh, T; Slogoff, S, 2003) |
| "The aim of this study was to assess the efficacy and safety of intravenous diltiazem to prevent myocardial ischemia during surgery on patients with ischemic heart disease undergoing non cardiac surgery under general anesthesia." | 9.08 | [Diltiazem compared with placebo in the prevention of myocardial ischemia during non-cardiac surgery]. ( Costa, A; García-Guasch, R; Llubià, C; Preciado, MJ; Sust, M; Vidal, F, 1998) |
| "Propofol and fentanyl preconditioning can protect the heart against acute ischemia and promote the recovery of hemodynamics during hemorrhagic shock." | 7.75 | Pretreatment with fentanyl and propofol attenuates myocardial injury in rabbits with acute hemorrhagic shock. ( Chai, W; Kuai, J; Liu, X; Tao, L; Yang, Y; Yao, L; Yu, D; Zeng, X, 2009) |
| "Neither halothane nor sevoflurane protected the heart against the effects of acute and severe regional myocardial ischemia." | 7.70 | Anesthetic modulation of myocardial ischemia and reperfusion injury in pigs: comparison between halothane and sevoflurane. ( Coetzee, A; Coetzee, J; Conradie, S, 1999) |
| "This study compares remifentanil/propofol (remi/prop) with isoflurane/fentanyl (iso/fen) anesthesia to determine which provides the greater hemodynamic stability, lesser myocardial ischemia, and morbidity with better postoperative outcomes after carotid endarterectomy." | 5.10 | Hemodynamic stability, myocardial ischemia, and perioperative outcome after carotid surgery with remifentanil/propofol or isoflurane/fentanyl anesthesia. ( Baker, WH; Jellish, WS; Louie, EK; Sheikh, T; Slogoff, S, 2003) |
| " Cardiac morbidity (postoperative myocardial ischemia, postoperative myocardial infarction, and perioperative sympathoadrenal stress response), respiratory morbidity (postextubation apnea, alveolar-arterial oxygen gradient, pulmonary shunting, oxygen consumption, atelectasis, and reintubation), hemodynamic values and vasoactive medication requirements, intraoperative awareness, postoperative cognitive function, 30 day mortality, and intensive care unit and hospital lengths of stay were compared between the two groups." | 5.08 | Morbidity outcome in early versus conventional tracheal extubation after coronary artery bypass grafting: a prospective randomized controlled trial. ( Asokumar, B; Carroll, J; Cheng, DC; David, T; Karski, J; Mickle, D; Nierenberg, H; Peniston, C; Raveendran, G; Roger, S; Sandler, A; Tong, J; Zelovitsky, J, 1996) |
| "The aim of this study was to assess the efficacy and safety of intravenous diltiazem to prevent myocardial ischemia during surgery on patients with ischemic heart disease undergoing non cardiac surgery under general anesthesia." | 5.08 | [Diltiazem compared with placebo in the prevention of myocardial ischemia during non-cardiac surgery]. ( Costa, A; García-Guasch, R; Llubià, C; Preciado, MJ; Sust, M; Vidal, F, 1998) |
| "Propofol and fentanyl preconditioning can protect the heart against acute ischemia and promote the recovery of hemodynamics during hemorrhagic shock." | 3.75 | Pretreatment with fentanyl and propofol attenuates myocardial injury in rabbits with acute hemorrhagic shock. ( Chai, W; Kuai, J; Liu, X; Tao, L; Yang, Y; Yao, L; Yu, D; Zeng, X, 2009) |
| "We investigated the involvement of central and peripheral opioid receptors (OR) in the cardioprotective effects of fentanyl (FENT) in a model of myocardial ischemia/reperfusion injury associated with pharmacologically induced sympathetic overactivity in anesthetized rabbits." | 3.73 | Pharmacologic evidence for the involvement of central and peripheral opioid receptors in the cardioprotective effects of fentanyl. ( Lessa, MA; Tibiriçá, E, 2006) |
| "Fentanyl elicits significant cardioprotective effects in a model of arrhythmia resulting from the association of central sympathetic overactivity with myocardial ischemia in rabbits, independently from its systemic hemodynamic actions." | 3.72 | Cardioprotective action of fentanyl in a model of central sympathetic overactivity in rabbits: antiarrhythmic and anti-ischemic effects. ( Lessa, MA; Rodrigues, E; Tibiricá, E, 2004) |
| "Neither halothane nor sevoflurane protected the heart against the effects of acute and severe regional myocardial ischemia." | 3.70 | Anesthetic modulation of myocardial ischemia and reperfusion injury in pigs: comparison between halothane and sevoflurane. ( Coetzee, A; Coetzee, J; Conradie, S, 1999) |
| "Postoperative myocardial ischemia is associated with adverse cardiac outcome." | 2.68 | Epidural analgesia and intravenous patient-controlled analgesia result in similar rates of postoperative myocardial ischemia after aortic surgery. ( Bois, S; Boudreault, D; Couture, P; Fugère, F; Girard, D; Lacombe, P; Nadeau, N, 1997) |
| "Pretreatment with fentanyl was not significantly different than controls." | 1.32 | Differential effects of opioid peptides on myocardial ischemic tolerance. ( Bolling, SF; McNish, R; Romano, MA; Seymour, EM; Traynor, JR, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 23 (71.88) | 18.2507 |
| 2000's | 7 (21.88) | 29.6817 |
| 2010's | 2 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, J | 1 |
| Wang, Z | 1 |
| Ji, Y | 1 |
| Qian, H | 1 |
| Dong, N | 1 |
| Onk, D | 1 |
| Akarsu Ayazoğlu, T | 1 |
| Onk, OA | 1 |
| Aksüt, M | 1 |
| Günay, M | 1 |
| Turkmen, K | 1 |
| Özensoy, A | 1 |
| Yazıcı Ersoy, Ç | 1 |
| Çoban, A | 1 |
| Yao, L | 1 |
| Kuai, J | 1 |
| Liu, X | 1 |
| Yu, D | 1 |
| Yang, Y | 1 |
| Tao, L | 1 |
| Zeng, X | 1 |
| Chai, W | 1 |
| Jellish, WS | 1 |
| Sheikh, T | 1 |
| Baker, WH | 1 |
| Louie, EK | 1 |
| Slogoff, S | 1 |
| Romano, MA | 1 |
| McNish, R | 1 |
| Seymour, EM | 1 |
| Traynor, JR | 1 |
| Bolling, SF | 2 |
| Lessa, MA | 2 |
| Rodrigues, E | 1 |
| Tibiricá, E | 2 |
| Biswas, AK | 1 |
| Feldman, BL | 1 |
| Davis, DH | 1 |
| Zintz, EA | 1 |
| Gannedahl, P | 1 |
| Edner, M | 1 |
| Lindahl, SG | 1 |
| Ljungqvist, O | 1 |
| Canty, JM | 1 |
| Smith, TP | 1 |
| Hohner, P | 2 |
| Nancarrow, C | 1 |
| Backman, C | 2 |
| Häggmark, S | 2 |
| Johansson, G | 2 |
| Fridén, H | 1 |
| Diamond, G | 2 |
| Friedman, A | 2 |
| Reiz, S | 2 |
| Karp, K | 1 |
| White, JL | 1 |
| Myers, AK | 1 |
| Analouei, A | 1 |
| Kim, YD | 1 |
| Fulgencio, JP | 1 |
| Rimaniol, JM | 1 |
| Catoire, P | 1 |
| Bonnet, F | 1 |
| Furuya, Y | 1 |
| Atarashi, K | 1 |
| Tachibana, C | 1 |
| Kobayashi, N | 1 |
| Satoh, K | 1 |
| Ohe, Y | 1 |
| Spahn, DR | 1 |
| Hu, WC | 1 |
| Smith, LR | 1 |
| Leone, BJ | 1 |
| Lischke, V | 1 |
| Probst, S | 1 |
| Behne, M | 1 |
| Kessler, P | 1 |
| Cheng, DC | 1 |
| Karski, J | 1 |
| Peniston, C | 1 |
| Asokumar, B | 1 |
| Raveendran, G | 1 |
| Carroll, J | 1 |
| Nierenberg, H | 1 |
| Roger, S | 1 |
| Mickle, D | 1 |
| Tong, J | 1 |
| Zelovitsky, J | 1 |
| David, T | 1 |
| Sandler, A | 1 |
| Searle, NR | 1 |
| Martineau, RJ | 1 |
| Conzen, P | 1 |
| al-Hasani, A | 1 |
| Mark, L | 1 |
| Ebert, T | 1 |
| Muzi, M | 1 |
| Hodgins, LR | 1 |
| Piriou, V | 2 |
| Ross, S | 2 |
| Pigott, D | 1 |
| Evans, R | 1 |
| Foex, P | 2 |
| Bois, S | 1 |
| Couture, P | 1 |
| Boudreault, D | 1 |
| Lacombe, P | 1 |
| Fugère, F | 1 |
| Girard, D | 1 |
| Nadeau, N | 1 |
| Darvas, K | 1 |
| Molnár, Z | 1 |
| Irtó, I | 1 |
| Tarjányi, M | 1 |
| Flautner, L | 1 |
| Miller, RS | 1 |
| Peterson, GM | 1 |
| McLean, S | 1 |
| Möller, C | 1 |
| Muñoz, H | 1 |
| Ryder, WA | 1 |
| García-Guasch, R | 1 |
| Llubià, C | 1 |
| Preciado, MJ | 1 |
| Costa, A | 1 |
| Sust, M | 1 |
| Vidal, F | 1 |
| Conradie, S | 1 |
| Coetzee, A | 1 |
| Coetzee, J | 1 |
| Watanabe, S | 1 |
| Kono, Y | 1 |
| Kaneko, S | 1 |
| Kano, T | 1 |
| Wasnick, JD | 1 |
| Haile, KK | 1 |
| Acuff, T | 1 |
| Benedict, PE | 1 |
| Benedict, MB | 1 |
| Su, TP | 1 |
| Rieke, H | 1 |
| Kazmaier, S | 1 |
| Lange, H | 1 |
| Weyland, A | 1 |
| Sonntag, H | 1 |
| Scheinin, H | 1 |
| Virtanen, T | 1 |
| Kentala, E | 1 |
| Uotila, P | 1 |
| Laitio, T | 1 |
| Hartiala, J | 1 |
| Heikkilä, H | 1 |
| Sariola-Heinonen, K | 1 |
| Pullisaar, O | 1 |
| Yli-Mäyry, S | 1 |
| Jalonen, J | 1 |
| Vrána, M | 1 |
| Fejfar, Z | 1 |
| Hess, L | 1 |
| Blazek, Z | 1 |
13 trials available for fentanyl and Myocardial Ischemia
| Article | Year |
|---|---|
Comparison of TIVA and Desflurane Added to a Subanaesthetic Dose of Propofol in Patients Undergoing Coronary Artery Bypass Surgery: Evaluation of Haemodynamic and Stress Hormone Changes.
Topics: Aged; Aged, 80 and over; Anesthesia, Intravenous; Anesthetics, Inhalation; Aorta; Biomarkers; Body M | 2016 |
Hemodynamic stability, myocardial ischemia, and perioperative outcome after carotid surgery with remifentanil/propofol or isoflurane/fentanyl anesthesia.
Topics: Aged; Anesthetics, Combined; Anesthetics, Inhalation; Anesthetics, Intravenous; Carotid Artery Disea | 2003 |
Anaesthesia for abdominal vascular surgery in patients with coronary artery disease (CAD), Part I: Isoflurane produces dose-dependent coronary vasodilation.
Topics: Abdomen; Aged; Aged, 80 and over; Anesthesia; Coronary Circulation; Coronary Disease; Dose-Response | 1994 |
Anaesthesia for abdominal aortic surgery in patients with coronary artery disease, Part II: Effects of nitrous oxide on systemic and coronary haemodynamics, regional ventricular function and incidence of myocardial ischaemia.
Topics: Abdomen; Anesthesia; Coronary Circulation; Coronary Disease; Female; Fentanyl; Hemodynamics; Humans; | 1994 |
Clonidine and postoperative myocardial ischaemia.
Topics: Aged; Analgesia, Epidural; Aorta, Abdominal; Blood Pressure; Clonidine; Double-Blind Method; Drug Co | 1994 |
[ST segment changes in the ECG. Anesthesia induction with propofol, etomidate or midazolam in patients with coronary heart disease].
Topics: Aged; Anesthesia; Blood Pressure; Coronary Artery Bypass; Electrocardiography; Etomidate; Female; Fe | 1993 |
Morbidity outcome in early versus conventional tracheal extubation after coronary artery bypass grafting: a prospective randomized controlled trial.
Topics: Aged; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Apnea; Catecholamines; | 1996 |
Comparison of sevoflurane/fentanyl and isoflurane/fentanyl during elective coronary artery bypass surgery. Sevoflurane Venture Group.
Topics: Aged; Anesthetics, Inhalation; Coronary Artery Bypass; Electrocardiography, Ambulatory; Ethers; Fema | 1996 |
Epidural analgesia and intravenous patient-controlled analgesia result in similar rates of postoperative myocardial ischemia after aortic surgery.
Topics: Aged; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Ao | 1997 |
Effect of cardiopulmonary bypass on the plasma concentrations of fentanyl and alcuronium.
Topics: Adjuvants, Anesthesia; Aged; Aged, 80 and over; Alcuronium; Body Mass Index; Cardiopulmonary Bypass; | 1997 |
[Diltiazem compared with placebo in the prevention of myocardial ischemia during non-cardiac surgery].
Topics: Aged; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Atracurium; Calcium Ch | 1998 |
[Does method of anesthesia modify postoperative ischemia incidence? A study of patients after aortocoronary bypass operations].
Topics: Adult; Aged; Anesthesia, General; Coronary Artery Bypass; Electrocardiography; Enflurane; Fentanyl; | 1999 |
Epidural infusion of bupivacaine and fentanyl reduces perioperative myocardial ischaemia in elderly patients with hip fracture--a randomized controlled trial.
Topics: Aged; Aged, 80 and over; Anesthesia, Epidural; Anesthetics, Intravenous; Anesthetics, Local; Area Un | 2000 |
19 other studies available for fentanyl and Myocardial Ischemia
| Article | Year |
|---|---|
[Risk analysis of cardiovascular events in elderly hypertensive patients with different risk stratification during the perioperative period].
Topics: Aged; Anesthesia, General; Cardiac Output; Cardiovascular Diseases; Coronary Artery Disease; Fentany | 2015 |
Pretreatment with fentanyl and propofol attenuates myocardial injury in rabbits with acute hemorrhagic shock.
Topics: Anesthetics, Intravenous; Animals; Female; Fentanyl; Hemodynamics; Ischemic Preconditioning, Myocard | 2009 |
Differential effects of opioid peptides on myocardial ischemic tolerance.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adaptation | 2004 |
Cardioprotective action of fentanyl in a model of central sympathetic overactivity in rabbits: antiarrhythmic and anti-ischemic effects.
Topics: Anesthesia; Anesthetics, Intravenous; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Autonom | 2004 |
Myocardial ischemia as a result of severe benzodiazepine and opioid withdrawal.
Topics: Adjuvants, Anesthesia; Analgesics, Opioid; Benzodiazepines; Diazepam; Electrocardiography; Female; F | 2005 |
Pharmacologic evidence for the involvement of central and peripheral opioid receptors in the cardioprotective effects of fentanyl.
Topics: Animals; Arrhythmias, Cardiac; Cardiotonic Agents; Dose-Response Relationship, Drug; Female; Fentany | 2006 |
Minimal influence of anaesthesia and abdominal surgery on computerized vectorcardiography recordings.
Topics: Adult; Aged; Anesthesia, Intravenous; Anesthesia, Spinal; Bupivacaine; Cholecystectomy; Female; Fent | 1995 |
Adenosine-recruitable flow reserve is absent during myocardial ischemia in unanesthetized dogs studied in the basal state.
Topics: Adenosine; Analgesics; Anesthesia; Animals; Catecholamines; Coronary Circulation; Dogs; Droperidol; | 1995 |
Functional recovery of stunned myocardium is greater with halothane than fentanyl anaesthesia in dogs.
Topics: Anesthesia, General; Animals; Blood Pressure; Cardiac Output; Coronary Circulation; Dogs; Fentanyl; | 1994 |
[Comparison between diltiazem and nicardipine used during anesthesia for coronary revascularization].
Topics: Aged; Anesthesia, Inhalation; Depression, Chemical; Diltiazem; Female; Fentanyl; Hemodynamics; Human | 1994 |
Pacing-induced left ventricular asynchronies in dogs with critical coronary stenosis: mechanisms and effect of anesthetics.
Topics: Anesthetics; Animals; Arrhythmias, Cardiac; Blood Pressure; Cardiac Output; Cardiac Pacing, Artifici | 1993 |
Beneficial effect of concomitant administration of isoflurane and nicorandil.
Topics: Adenosine Triphosphate; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Drug Therapy, Co | 1997 |
Anaesthesiological indications and contraindications of minimally invasive surgery.
Topics: Acid-Base Equilibrium; Acidosis; Anesthesia, General; Anesthesia, Inhalation; Anesthesia, Intravenou | 1997 |
A comparison of the effects of fentanyl and propofol on left ventricular contractility during myocardial stunning.
Topics: Anesthetics, Intravenous; Animals; Aorta; Blood Pressure; Calcium Channel Blockers; Cardiac Output; | 1998 |
Anesthetic modulation of myocardial ischemia and reperfusion injury in pigs: comparison between halothane and sevoflurane.
Topics: Adjuvants, Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Fentanyl; Halotha | 1999 |
Effects of a bolus injection of adenosine triphosphate on atrioventricular conduction and hemodynamics in patients undergoing coronary artery bypass grafting.
Topics: Adenosine Triphosphate; Anesthetics, Intravenous; Atrioventricular Node; Blood Pressure; Bradycardia | 1999 |
Anesthetic management of minimally invasive laser transmyocardial revascularization.
Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Angina Pectoris; Desflurane; | 1999 |
Opiate drugs and delta-receptor-mediated myocardial protection.
Topics: Analgesics, Opioid; Animals; Buprenorphine; Cardiopulmonary Bypass; Fentanyl; Heart; Morphine; Myoca | 1999 |
Analgosedation raises baroreflex sensitivity in acute myocardial ischaemia.
Topics: Animals; Baroreflex; Conscious Sedation; Dogs; Electrocardiography; Fentanyl; Heart Ventricles; Hemo | 1992 |