fentanyl has been researched along with Myasthenia Gravis in 16 studies
Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.
Myasthenia Gravis: A disorder of neuromuscular transmission characterized by fatigable weakness of cranial and skeletal muscles with elevated titers of ACETYLCHOLINE RECEPTORS or muscle-specific receptor tyrosine kinase (MuSK) autoantibodies. Clinical manifestations may include ocular muscle weakness (fluctuating, asymmetric, external ophthalmoplegia; diplopia; ptosis; and weakness of eye closure) and extraocular fatigable weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles (ocular myasthenia). THYMOMA is commonly associated with this condition.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eleven myasthenia gravis and seven control patients were studied during N2O/O2-fentanyl anesthesia to determine the ED50, ED95, and maintenance requirement of vecuronium using both mechanomyography and electromyography." | 3.68 | Vecuronium dose-response and maintenance requirements in patients with myasthenia gravis. ( Meretoja, OA; Nilsson, E, 1990) |
| "Patients diagnosed with ocular myasthenia gravis (MG) and mitral valve disease represent a significant perioperative management problem, especially for the anaesthesiologist, due to complex inter-actions between the disease, drugs to treat the disease, and anaesthetic agents, such as neuromuscu-lar blocking agents (NMBAs)." | 1.51 | Mitral Valve Replacement with Thymectomy in a Patient with Ocular Myasthenia Gravis: Case Report. ( Chioncel, O; Filipescu, D; Geana, RC; Iliescu, VA; Radu, R; Sorostinean, D; Stefan, M; Stiru, O, 2019) |
| "Juvenile myasthenia gravis is the acquired form of the disease in children and presents with ocular signs, fatigability, weakness and bulbar problems." | 1.34 | A combination of total intravenous anesthesia and thoracic epidural for thymectomy in juvenile myasthenia gravis. ( Bagshaw, O, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (25.00) | 18.7374 |
| 1990's | 5 (31.25) | 18.2507 |
| 2000's | 6 (37.50) | 29.6817 |
| 2010's | 1 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stiru, O | 1 |
| Stefan, M | 1 |
| Geana, RC | 1 |
| Sorostinean, D | 1 |
| Radu, R | 1 |
| Filipescu, D | 1 |
| Chioncel, O | 1 |
| Iliescu, VA | 1 |
| Hepağuşlar, H | 1 |
| Oztekin, S | 1 |
| Capar, E | 1 |
| Elar, Z | 1 |
| Bouaggad, A | 1 |
| Bouderka, MA | 1 |
| Abassi, O | 1 |
| Mekis, D | 1 |
| Kamenik, M | 1 |
| El-Dawlatly, AA | 1 |
| Al Kattan, K | 1 |
| Hajjar, W | 1 |
| Essa, M | 1 |
| Delvi, B | 1 |
| Khoja, A | 1 |
| Bagshaw, O | 1 |
| Narimatsu, E | 1 |
| Munemura, Y | 1 |
| Kawamata, M | 1 |
| Imaizumi, H | 1 |
| Namiki, A | 1 |
| Iwasaki, H | 1 |
| Florence, AM | 1 |
| Frazer, RS | 1 |
| Chalkiadis, GA | 1 |
| Petzinger, G | 1 |
| Mayer, SA | 1 |
| Przedborski, S | 1 |
| Ishimura, H | 1 |
| Sata, T | 1 |
| Matsumoto, T | 1 |
| Takizuka, A | 1 |
| Shigematsu, A | 1 |
| Hamaguchi, S | 1 |
| Kitajima, T | 1 |
| Yasuda, S | 1 |
| Nilsson, E | 1 |
| Meretoja, OA | 1 |
| Burgess, FW | 1 |
| Wilcosky, B | 1 |
| Yusa, T | 1 |
| Sugiu, T | 1 |
| Sato, T | 1 |
2 trials available for fentanyl and Myasthenia Gravis
| Article | Year |
|---|---|
Total intravenous anaesthesia with propofol for myasthenic patients.
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Fentanyl; Humans; Intubation, Intratracheal; Lary | 2005 |
Anaesthesia for transcervical thymectomy in myasthenia gravis.
Topics: Adult; Alfaxalone Alfadolone Mixture; Anesthesia, Inhalation; Anesthesia, Intravenous; Etomidate; Fe | 1984 |
14 other studies available for fentanyl and Myasthenia Gravis
| Article | Year |
|---|---|
Mitral Valve Replacement with Thymectomy in a Patient with Ocular Myasthenia Gravis: Case Report.
Topics: Adult; Anesthetics, Combined; Anti-Inflammatory Agents; Drug Interactions; Female; Fentanyl; Heart V | 2019 |
Recovery from remifentanil after plasmapheresis in a paediatric patient with myasthenia gravis.
Topics: Adolescent; Analgesics, Opioid; Anesthesia Recovery Period; Anesthetics, Intravenous; Female; Fentan | 2003 |
Remifentanil and high thoracic epidural anaesthesia: a successful combination for patients with myasthenia gravis undergoing transsternal thymectomy.
Topics: Adult; Analgesics, Opioid; Anesthesia, Epidural; Anesthetics, Combined; Anesthetics, Intravenous; An | 2005 |
Anesthetic implications for video assisted thoracoscopic thymectomy in myasthenia gravis.
Topics: Adult; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Anesthetics, Local; A | 2005 |
A combination of total intravenous anesthesia and thoracic epidural for thymectomy in juvenile myasthenia gravis.
Topics: Adolescent; Amides; Anesthesia, Epidural; Anesthesia, Intravenous; Anesthetics, Combined; Anesthetic | 2007 |
Tracheal intubation without neuromuscular relaxants for thymectomy in myasthenic patients.
Topics: Adult; Aged; Anesthesia; Anesthetics, Intravenous; Female; Fentanyl; Humans; Intubation, Intratrache | 2003 |
Anaesthesia and undiagnosed myasthenia gravis.
Topics: Aged; Aged, 80 and over; Anesthesia, Intravenous; Electromyography; Eyelids; Female; Fentanyl; Human | 1995 |
Fentanyl-induced dyskinesias.
Topics: Brain; Fentanyl; Humans; Hypnotics and Sedatives; Injections, Epidural; Male; Middle Aged; Movement | 1995 |
Anesthetic management of a patient with myasthenia gravis during hypothermic cardiopulmonary bypass.
Topics: Aged; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Intravenous; Antibodies; Car | 1998 |
[Anesthetic management of a patient with postthymectomy myasthenia gravis].
Topics: Anesthesia, Epidural; Anesthesia, General; Anesthetics, Intravenous; Disease Progression; Fentanyl; | 1999 |
High-dose fentanyl.
Topics: Adult; Anesthesia, Intravenous; Fentanyl; Humans; Infusions, Parenteral; Middle Aged; Myasthenia Gra | 1979 |
Vecuronium dose-response and maintenance requirements in patients with myasthenia gravis.
Topics: Adult; Anesthesia, Inhalation; Dose-Response Relationship, Drug; Electromyography; Female; Fentanyl; | 1990 |
Thoracic epidural anesthesia for transsternal thymectomy in myasthenia gravis.
Topics: Adult; Anesthesia, Epidural; Female; Fentanyl; Graves Disease; Humans; Lidocaine; Myasthenia Gravis; | 1989 |
[Experience of neuroleptanesthesia in myasthenia accompanied by the WPW syndrome].
Topics: Adult; Benperidol; Electrocardiography; Female; Fentanyl; Humans; Myasthenia Gravis; Neuroleptanalge | 1972 |