Page last updated: 2024-10-27

fentanyl and Musculoskeletal Pain

fentanyl has been researched along with Musculoskeletal Pain in 7 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Musculoskeletal Pain: Discomfort stemming from muscles, LIGAMENTS, tendons, and bones.

Research Excerpts

ExcerptRelevanceReference
" We evaluated the efficacy of sublingual fentanyl tablet (SLF) for the treatment of BTP in opioid-tolerant patients with chronic musculoskeletal pain with neuropathic component in terms of relief of pain intensity and assessed whether hypothetical pain relief impacts on quality of life (QoL)."9.20Efficacy and safety of sublingual fentanyl tablets for the management of breakthrough pain in patients with chronic musculoskeletal pain with neuropathic component: multicenter prospective study. ( Camba-Rodríguez, A; Cánovas-Martínez, L; Carceller-Ruiz, JJ; De la Iglesia-López, A; Díaz-Parada, P; Domínguez-Suárez, E; Freire-Vila, E; Iglesias, BG; Illodo-Miramontes, G; López-Ulloa, B, 2015)
" We evaluated the efficacy of sublingual fentanyl tablet (SLF) for the treatment of BTP in opioid-tolerant patients with chronic musculoskeletal pain with neuropathic component in terms of relief of pain intensity and assessed whether hypothetical pain relief impacts on quality of life (QoL)."5.20Efficacy and safety of sublingual fentanyl tablets for the management of breakthrough pain in patients with chronic musculoskeletal pain with neuropathic component: multicenter prospective study. ( Camba-Rodríguez, A; Cánovas-Martínez, L; Carceller-Ruiz, JJ; De la Iglesia-López, A; Díaz-Parada, P; Domínguez-Suárez, E; Freire-Vila, E; Iglesias, BG; Illodo-Miramontes, G; López-Ulloa, B, 2015)
"7%) reduced benzodiazepines dosage when prescribing potent opioids."1.56Strong opioids and non-cancer chronic pain in Catalonia. An analysis of the family physicians prescription patterns. ( Adriyanov, B; Álvarez Carrera, MA; Dürsteler, C; Perelló Bratescu, A; Riera Nadal, N; Sisó-Almirall, A, 2020)
"While acute musculoskeletal pain is a frequent complaint, its management is often neglected."1.43A nurse-initiated pain protocol in the ED improves pain treatment in patients with acute musculoskeletal pain. ( Berben, SA; Doggen, CJ; Gaakeer, MI; IJzerman, MJ; Pierik, JG; van Eenennaam, FL; van Vugt, AB, 2016)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (85.71)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Perelló Bratescu, A1
Adriyanov, B1
Dürsteler, C1
Sisó-Almirall, A1
Álvarez Carrera, MA1
Riera Nadal, N1
Benoist, GE1
van Oort, IM1
Burger, DM1
Koch, BCP1
Mehra, N1
van Erp, NP1
Graudins, A1
Meek, R1
Egerton-Warburton, D1
Seith, R1
Furness, T1
Chapman, R1
Cánovas-Martínez, L1
Carceller-Ruiz, JJ1
Díaz-Parada, P1
Illodo-Miramontes, G1
Freire-Vila, E1
De la Iglesia-López, A1
Iglesias, BG1
López-Ulloa, B1
Domínguez-Suárez, E1
Camba-Rodríguez, A1
Pierik, JG1
Berben, SA1
IJzerman, MJ1
Gaakeer, MI1
van Eenennaam, FL1
van Vugt, AB1
Doggen, CJ1
Chew, KS1
Shaharudin, AH1
Chen, YK1
Lei, J1
Jin, L1
Tan, YX1
You, HJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of Sub-dissociative Dose Intranasal Ketamine to Intranasal Fentanyl for Treatment of Moderate to Severe Pain in Pediatric Patients Presenting to the Emergency Department: a Prospective, Randomized, Double-blind Study[NCT02388321]Phase 422 participants (Actual)Interventional2015-05-01Terminated (stopped due to Patients meeting inclusion criteria was low, and PI went to another institution.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Adverse Events at 30 Minutes

The patient were asked at 30 minutes post administration of analgesia if they experienced any side effects like nausea, vomiting, headache etc. (NCT02388321)
Timeframe: 30 minutes

InterventionParticipants (Count of Participants)
Ketamine0
Fentanyl0

Pain Score at 30 Minutes

An 11 point Likert Visual Analog Scale with 0 being no pain, 5 being moderate pain and 10 being very severe pain was verbally administered to the patient at 30 minutes post administration of analgesia. (NCT02388321)
Timeframe: 30 minutes

Interventionunits on a scale (Mean)
Ketamine3.36
Fentanyl2.09

Trials

3 trials available for fentanyl and Musculoskeletal Pain

ArticleYear
The PICHFORK (Pain InCHildren Fentanyl OR Ketamine) trial comparing the efficacy of intranasal ketamine and fentanyl in the relief of moderate to severe pain in children with limb injuries: study protocol for a randomized controlled trial.
    Trials, 2013, Jul-10, Volume: 14

    Topics: Administration, Intranasal; Adolescent; Age Factors; Analgesics; Analgesics, Opioid; Arm Injuries; C

2013
Efficacy and safety of sublingual fentanyl tablets for the management of breakthrough pain in patients with chronic musculoskeletal pain with neuropathic component: multicenter prospective study.
    Clinical drug investigation, 2015, Volume: 35, Issue:3

    Topics: Administration, Sublingual; Adult; Aged; Aged, 80 and over; Breakthrough Pain; Drug-Related Side Eff

2015
An open-label randomised controlled trial on the efficacy of adding intranasal fentanyl to intravenous tramadol in patients with moderate to severe pain following acute musculoskeletal injuries.
    Singapore medical journal, 2017, Volume: 58, Issue:10

    Topics: Administration, Intranasal; Administration, Intravenous; Adolescent; Adult; Aged; Analgesics, Opioid

2017

Other Studies

4 other studies available for fentanyl and Musculoskeletal Pain

ArticleYear
Strong opioids and non-cancer chronic pain in Catalonia. An analysis of the family physicians prescription patterns.
    Revista espanola de anestesiologia y reanimacion, 2020, Volume: 67, Issue:2

    Topics: Analgesics, Opioid; Benzodiazepines; Chronic Pain; Female; Fentanyl; Health Care Surveys; Humans; La

2020
The Combination of Enzalutamide and Opioids: A Painful Pitfall?
    European urology, 2019, Volume: 75, Issue:2

    Topics: Analgesics, Opioid; Androgen Antagonists; Antineoplastic Agents; Benzamides; Bone Neoplasms; Cytochr

2019
A nurse-initiated pain protocol in the ED improves pain treatment in patients with acute musculoskeletal pain.
    International emergency nursing, 2016, Volume: 27

    Topics: Acetaminophen; Adult; Analgesics; Diclofenac; Emergency Service, Hospital; Female; Fentanyl; Follow-

2016
Dynamic variations of c-Fos expression in the spinal cord exposed to intramuscular hypertonic saline-induced muscle nociception.
    European journal of pain (London, England), 2013, Volume: 17, Issue:3

    Topics: Analgesics, Opioid; Animals; Fentanyl; Functional Laterality; Gene Expression; Genes, fos; Immunohis

2013