Page last updated: 2024-10-27

fentanyl and Muscle Relaxation

fentanyl has been researched along with Muscle Relaxation in 34 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.

Research Excerpts

ExcerptRelevanceReference
" The dosage of propofol needed for induction, consumption during maintenance and recovery time were recorded."5.40Impact of malnutrition on propofol consumption and recovery time among patients undergoing laparoscopic gastrointestinal surgery. ( Bu, H; Fan, Y; Gao, F; Manyande, A; Tian, X; Tian, Y; Xiang, Y; Yang, H, 2014)
" with Steyn modification which includes five criteria; ease of laryngoscopy, degree of coughing, position of vocal cords, jaw relaxation, and limb movement and graded on a 4-point scale."5.12Comparative evaluation of different doses of propofol preceded by fentanyl on intubating conditions and pressor response during tracheal intubation without muscle relaxants. ( Gupta, A; Kale, S; Kaur, R; Malhotra, R, 2006)
"To report the use of regional anesthesia and iv nitroglycerin to provide anesthesia and uterine relaxation for three Cesarean deliveries (CD) involving ex utero intrapartum treatment (EXIT) of potentially life-threatening airway obstruction in the newborn."3.74Case series: Combined spinal epidural anesthesia for Cesarean delivery and ex utero intrapartum treatment procedure. ( George, RB; Habib, AS; Melnick, AH; Rose, EC, 2007)
" The tracheas were intubated after fentanyl/propofol without the aid of muscle relaxation."3.70Surface vs intramuscular laryngeal electromyography. ( Hemmerling, TM; Jacobi, KE; Schmidt, J; Wolf, SR; Wolf, T, 2000)
"Pancuronium and a continuous infusion of althesin was used to produce muscular relaxation in a patient with myotonic dystrophy."3.65Case report: anaesthesia in myotonic dystrophy. ( Muller, J; Suppan, P, 1977)
" In the first study, the doses (in milligrams per kilogram) of ORG9426 that caused 50% (ED50), 90% (ED90), or 95% (ED95) neuromuscular block were determined by the individual dose-response method; they were 0."2.67The neuromuscular effects of ORG9426 in patients receiving balanced anesthesia. ( Foldes, FF; Mason, MM; Nagashima, H; Nguyen, HD; Ohta, Y; Schiller, WS, 1991)
" The dosage of propofol needed for induction, consumption during maintenance and recovery time were recorded."1.40Impact of malnutrition on propofol consumption and recovery time among patients undergoing laparoscopic gastrointestinal surgery. ( Bu, H; Fan, Y; Gao, F; Manyande, A; Tian, X; Tian, Y; Xiang, Y; Yang, H, 2014)
"Fentanyl is an attractive agent for analgesia in the emergency department."1.28Continuous intravenous infusion fentanyl for sedation and analgesia of the multiple trauma patient. ( Ferlic, FJ; Smith, GA; Walsh, M; Wieschhaus, MF; Yount, RA, 1991)
"Muscle relaxation was provided by competitive neuromuscular blockade, allowing controlled ventilation of the lungs with oxygen-enriched air."1.26Total intravenous anaesthesia for major gynaecological surgery. ( Brock-Utne, JG; Downing, JW; Rocke, DA; Rubin, J, 1981)
"5 to 1 microgram/kg) than by increasing the dosage of thiopental."1.26The role of different components of balanced anaesthesia in tolerance to endotracheal intubation. ( Aromaa, U; Tammisto, T, 1977)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199012 (35.29)18.7374
1990's9 (26.47)18.2507
2000's11 (32.35)29.6817
2010's2 (5.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tian, X1
Xiang, Y1
Fan, Y1
Bu, H1
Yang, H1
Manyande, A1
Gao, F1
Tian, Y1
Narayanaswamy, M1
Aissaoui, Y1
Qamous, Y1
Serghini, I1
Zoubir, M1
Salim, JL1
Boughalem, M1
Jabbour-Khoury, SI1
Dabbous, AS1
Rizk, LB1
Abou Jalad, NM1
Bartelmaos, TE1
El-Khatib, MF1
Baraka, AS1
Sohn, JT1
Ok, SH1
Kim, HJ1
Moon, SH1
Shin, IW1
Lee, HK1
Chung, YK1
Sahin, AS1
Duman, A1
Atalik, EK1
Ogün, CO1
Sahin, TK1
Erol, A1
Ozergin, U1
Gupta, A1
Kaur, R1
Malhotra, R1
Kale, S1
Nakatsuka, M1
Franks, P1
Keenan, RL1
George, RB1
Melnick, AH1
Rose, EC1
Habib, AS1
Woloszczuk-Gebicka, B1
Wyska, E1
Grabowski, T1
Lefebvre, RA2
Willems, JL2
Bogaert, MG1
Rocke, DA1
Rubin, J1
Brock-Utne, JG1
Downing, JW1
Appukutty, VG1
Rajendran, SK1
Krishnan, M1
Bhushnam, KV1
Mallika, T1
Ionides, SP1
Weiss, MG1
Angelopoulos, M1
Myers, TF1
Handa, RJ1
Lee, K1
Hatake, K1
Hishida, S1
Tsujita, T1
Shibata, O1
Makita, T1
Iwanaga, S1
Nakamura, H1
Fukusaki, M1
Sumikawa, K1
Kelicen, P1
Ismailoglu, UB1
Erdemli, O1
Sahin-Erdemli, I1
van Dongen, EP1
ter Beek, HT1
Schepens, MA1
Morshuis, WJ1
Langemeijer, HJ1
Kalkman, CJ1
Boezeman, EH1
Hemmerling, TM1
Schmidt, J1
Wolf, T1
Wolf, SR1
Jacobi, KE1
Grobler, D2
Bush, M2
Jessup, D1
Lance, W2
Hanouz, JL1
Yvon, A1
Guesne, G1
Eustratiades, C1
Babatasi, G1
Rouet, R1
Ducouret, P1
Khayat, A1
Bricard, H1
Gérard, JL1
Citino, SB1
Kurka, P1
Tammisto, T2
Tigerstedt, I1
Aromaa, U1
Muller, J1
Suppan, P1
Gyermek, L1
Henderson, G1
Sloan, MH1
Lerman, J1
Bissonnette, B1
Walsh, M1
Smith, GA1
Yount, RA1
Ferlic, FJ1
Wieschhaus, MF1
Foldes, FF1
Nagashima, H1
Nguyen, HD1
Schiller, WS1
Mason, MM1
Ohta, Y1
Wang, BG1
Wang, XC1
Kunjappan, VE1
Brown, EM1
Alexander, GD1
Peeters, ME1
Gil, D1
Teske, E1
Eyzenbach, V1
vd Brom, WE1
Lumeij, JT1
de Vries, HW1

Trials

7 trials available for fentanyl and Muscle Relaxation

ArticleYear
Magnesium sulphate: an adjuvant to tracheal intubation without muscle relaxation--a randomised study.
    European journal of anaesthesiology, 2012, Volume: 29, Issue:8

    Topics: Adjuvants, Anesthesia; Adult; Analysis of Variance; Anesthesia, General; Anesthetics, Intravenous; C

2012
A combination of alfentanil-lidocaine-propofol provides better intubating conditions than fentanyl-lidocaine-propofol in the absence of muscle relaxants.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2003, Volume: 50, Issue:2

    Topics: Adult; Alfentanil; Analgesics, Opioid; Anesthetics, Intravenous; Anesthetics, Local; Blood Pressure;

2003
Comparative evaluation of different doses of propofol preceded by fentanyl on intubating conditions and pressor response during tracheal intubation without muscle relaxants.
    Paediatric anaesthesia, 2006, Volume: 16, Issue:4

    Topics: Anesthesia, General; Anesthetics, Intravenous; Blood Pressure; Child; Child, Preschool; Cough; Doubl

2006
A method of rapid-sequence induction using high-dose narcotics with vecuronium or vecuronium and pancuronium in patients with coronary artery disease.
    Journal of cardiothoracic anesthesia, 1988, Volume: 2, Issue:2

    Topics: Anesthetics, Combined; Coronary Artery Bypass; Coronary Artery Disease; Dose-Response Relationship,

1988
Plasma beta-endorphin concentrations and analgesia-muscle relaxation in the newborn infant supported by mechanical ventilation.
    The Journal of pediatrics, 1994, Volume: 125, Issue:1

    Topics: beta-Endorphin; Female; Fentanyl; Humans; Infant, Newborn; Male; Morphine; Muscle Relaxation; Pancur

1994
Pharmacodynamics of high-dose vecuronium in children during balanced anesthesia.
    Anesthesiology, 1991, Volume: 74, Issue:4

    Topics: Anesthesia, Intravenous; Child; Child, Preschool; Dose-Response Relationship, Drug; Electromyography

1991
The neuromuscular effects of ORG9426 in patients receiving balanced anesthesia.
    Anesthesiology, 1991, Volume: 75, Issue:2

    Topics: Adult; Aged; Androstanols; Anesthesia, Intravenous; Dose-Response Relationship, Drug; Droperidol; Fe

1991

Other Studies

27 other studies available for fentanyl and Muscle Relaxation

ArticleYear
Impact of malnutrition on propofol consumption and recovery time among patients undergoing laparoscopic gastrointestinal surgery.
    Acta anaesthesiologica Scandinavica, 2014, Volume: 58, Issue:8

    Topics: Accelerometry; Aged; Anesthesia Recovery Period; Anesthesia, General; Anesthesia, Intravenous; Anest

2014
Decrease in Bispectral Index while correcting hyperglycemia and an increase in Bispectral Index with correction of hypoglycemia.
    Anesthesia and analgesia, 2009, Volume: 109, Issue:3

    Topics: Aged; Anesthesia; Anesthesiology; Blood Glucose; Electroencephalography; Female; Fentanyl; Humans; H

2009
Inhibitory effect of fentanyl on acetylcholine-induced relaxation in rat aorta.
    Anesthesiology, 2004, Volume: 101, Issue:1

    Topics: Acetylcholine; Analgesics, Opioid; Animals; Aorta, Thoracic; Calcimycin; Dose-Response Relationship,

2004
The mechanisms of the direct vascular effects of fentanyl on isolated human saphenous veins in vitro.
    Journal of cardiothoracic and vascular anesthesia, 2005, Volume: 19, Issue:2

    Topics: Analgesics, Opioid; Calcium Channels; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; D

2005
Case series: Combined spinal epidural anesthesia for Cesarean delivery and ex utero intrapartum treatment procedure.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2007, Volume: 54, Issue:3

    Topics: Adult; Airway Obstruction; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesia, Spinal; Bupiva

2007
Sevoflurane increases fade of neuromuscular response to TOF stimulation following rocuronium administration in children. A PK/PD analysis.
    Paediatric anaesthesia, 2007, Volume: 17, Issue:7

    Topics: Androstanols; Anesthetics, Inhalation; Anesthetics, Intravenous; Blood Pressure; Body Temperature; C

2007
Gastric relaxation and vomiting by apomorphine, morphine and fentanyl in the conscious dog.
    European journal of pharmacology, 1981, Jan-16, Volume: 69, Issue:2

    Topics: Animals; Apomorphine; Dogs; Dopamine Antagonists; Drug Interactions; Female; Fentanyl; Morphine; Mus

1981
Total intravenous anaesthesia for major gynaecological surgery.
    Anaesthesia and intensive care, 1981, Volume: 9, Issue:2

    Topics: Adult; Aged; Anesthesia, Intravenous; Blood Pressure; Etomidate; Female; Fentanyl; Genital Diseases,

1981
Neuroleptanaesthesia in paediatric practice.
    Annals of the Academy of Medicine, Singapore, 1981, Volume: 10, Issue:4

    Topics: Anesthesia, General; Child; Droperidol; Fentanyl; Heart Rate; Humans; Infant; Muscle Relaxation; Pos

1981
[Inhibitory effect of fentanyl citrate on endothelium-dependent relaxation in rat aorta].
    Masui. The Japanese journal of anesthesiology, 1994, Volume: 43, Issue:1

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Endothelium, Vascular; Fentanyl; In Vitro Techniques; Male;

1994
Effects of intravenous anesthetics on the contraction and response of rat trachea to phosphatidylinositol.
    Research communications in molecular pathology and pharmacology, 1997, Volume: 95, Issue:3

    Topics: Analysis of Variance; Anesthetics, Intravenous; Animals; Carbachol; Fentanyl; Ketamine; Male; Midazo

1997
The effect of propofol and thiopentone on impairment by reactive oxygen species of endothelium-dependent relaxation in rat aortic rings.
    European journal of anaesthesiology, 1997, Volume: 14, Issue:3

    Topics: Acetylcholine; Anesthetics, Intravenous; Animals; Aorta, Thoracic; Endothelium, Vascular; Etomidate;

1997
The influence of nitrous oxide to supplement fentanyl/low-dose propofol anesthesia on transcranial myogenic motor-evoked potentials during thoracic aortic surgery.
    Journal of cardiothoracic and vascular anesthesia, 1999, Volume: 13, Issue:1

    Topics: Action Potentials; Aged; Anesthetics, Combined; Anesthetics, Inhalation; Anesthetics, Intravenous; A

1999
Surface vs intramuscular laryngeal electromyography.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2000, Volume: 47, Issue:9

    Topics: Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Atracurium; Electric Stimulation; Electrode

2000
Anaesthesia of gemsbok (Oryx gazella) with a combination of A3080, medetomidine and ketamine.
    Journal of the South African Veterinary Association, 2001, Volume: 72, Issue:2

    Topics: Analgesics; Anesthesia; Animals; Antelopes; Drug Combinations; Drug Synergism; Fentanyl; Heart Rate;

2001
The in vitro effects of remifentanil, sufentanil, fentanyl, and alfentanil on isolated human right atria.
    Anesthesia and analgesia, 2001, Volume: 93, Issue:3

    Topics: Aged; Alfentanil; Anesthetics, Intravenous; Atrial Function, Right; Female; Fentanyl; Heart; Heart A

2001
Anaesthesia of roan antelope (Hippotragus equinus) with a combination of A3080, medetomidine and ketamine.
    Journal of the South African Veterinary Association, 2001, Volume: 72, Issue:1

    Topics: Analgesics; Anesthesia; Anesthetics, Combined; Animals; Antelopes; Dose-Response Relationship, Drug;

2001
[Clinical experience with flunitrazepam combination anesthesia].
    Klinische Anasthesiologie und Intensivtherapie, 1978, Issue:17

    Topics: Anesthesia; Anti-Anxiety Agents; Barbiturates; Droperidol; Drug Combinations; Drug Interactions; Ele

1978
The need for fentanyl supplementation of N2O-O2 relaxant anaesthesia in chronic alcoholics.
    Acta anaesthesiologica Scandinavica, 1977, Volume: 21, Issue:3

    Topics: Adult; Aged; Alcoholism; Anesthesia, Inhalation; Biliary Tract Surgical Procedures; Drug Resistance;

1977
Gastric relaxation by morphine, apomorphine and fentanyl in the conscious dog.
    Archives internationales de pharmacodynamie et de therapie, 1979, Volume: 242, Issue:2

    Topics: Animals; Apomorphine; Benzimidazoles; Dogs; Domperidone; Fentanyl; Haloperidol; Morphine; Muscle Con

1979
The role of different components of balanced anaesthesia in tolerance to endotracheal intubation.
    Annales chirurgiae et gynaecologiae. Supplementum, 1977, Volume: 66, Issue:5

    Topics: Adult; Anesthesia; Female; Fentanyl; Humans; Intubation, Intratracheal; Male; Middle Aged; Muscle Re

1977
Case report: anaesthesia in myotonic dystrophy.
    Anaesthesia and intensive care, 1977, Volume: 5, Issue:1

    Topics: Adult; Alfaxalone Alfadolone Mixture; Anesthesia, General; Electromyography; Female; Fentanyl; Human

1977
Electromyographic monitoring of profound surgical muscle relaxation during cardiac anesthesia.
    Journal of clinical monitoring, 1992, Volume: 8, Issue:2

    Topics: Anesthesia, General; Anesthetics; Cardiac Surgical Procedures; Diazepam; Droperidol; Electric Stimul

1992
Continuous intravenous infusion fentanyl for sedation and analgesia of the multiple trauma patient.
    Annals of emergency medicine, 1991, Volume: 20, Issue:8

    Topics: Adult; Analgesia; Female; Fentanyl; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Multipl

1991
[Studies on the rapid induction of general anesthesia].
    Zhonghua yi xue za zhi, 1989, Volume: 69, Issue:3

    Topics: Adjuvants, Anesthesia; Adolescent; Adult; Anesthesia, General; Cardiography, Impedance; Female; Fent

1989
Rapid sequence induction using vecuronium.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:5

    Topics: Adolescent; Adult; Aged; Dose-Response Relationship, Drug; Female; Fentanyl; Humans; Intubation, Int

1986
Four methods for general anaesthesia in the rabbit: a comparative study.
    Laboratory animals, 1988, Volume: 22, Issue:4

    Topics: Anesthesia, General; Anesthesia, Inhalation; Anesthetics, Dissociative; Animals; Barbiturates; Fenta

1988