fentanyl has been researched along with Metabolism, Inborn Errors in 1 studies
Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.
Metabolism, Inborn Errors: Errors in metabolic processes resulting from inborn genetic mutations that are inherited or acquired in utero.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Debrisoquine was a weak, noncompetitive inhibitor of alfentanil metabolism and of the formation of its major metabolites, with Ki values between 2." | 1.27 | Is the metabolism of alfentanil subject to debrisoquine polymorphism? A study using human liver microsomes. ( Hendrickx, JJ; Heykants, JJ; Lauwers, W; Lavrijsen, KL; Meuldermans, WE; Van Dyck, DM; Van Houdt, JM; Woestenborghs, RJ, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lavrijsen, KL | 1 |
| Van Houdt, JM | 1 |
| Van Dyck, DM | 1 |
| Hendrickx, JJ | 1 |
| Woestenborghs, RJ | 1 |
| Lauwers, W | 1 |
| Meuldermans, WE | 1 |
| Heykants, JJ | 1 |
1 other study available for fentanyl and Metabolism, Inborn Errors
| Article | Year |
|---|---|
Is the metabolism of alfentanil subject to debrisoquine polymorphism? A study using human liver microsomes.
Topics: Alfentanil; Chromatography, High Pressure Liquid; Debrisoquin; Fentanyl; Humans; Hydroxylation; Isoq | 1988 |