fentanyl has been researched along with Liver Failure in 2 studies
Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.
Liver Failure: Severe inability of the LIVER to perform its normal metabolic functions, as evidenced by severe JAUNDICE and abnormal serum levels of AMMONIA; BILIRUBIN; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; LACTATE DEHYDROGENASES; and albumin/globulin ratio. (Blakiston's Gould Medical Dictionary, 4th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Opioids and especially fentanyl are widely used during the intensive care unit management of intracranial pressure in fulminant hepatic failure patients as well as during and after liver transplantation." | 7.73 | The effect of acutely induced hepatic failure on remifentanil and fentanyl blood levels in a pig model. ( Andreadou, I; Arkadopoulos, N; Charalambidis, G; Chondroudaki, J; Costopanagiotou, C; Kostopanagiotou, G; Markantonis, SL; Smyrniotis, V, 2006) |
| "Opioids and especially fentanyl are widely used during the intensive care unit management of intracranial pressure in fulminant hepatic failure patients as well as during and after liver transplantation." | 3.73 | The effect of acutely induced hepatic failure on remifentanil and fentanyl blood levels in a pig model. ( Andreadou, I; Arkadopoulos, N; Charalambidis, G; Chondroudaki, J; Costopanagiotou, C; Kostopanagiotou, G; Markantonis, SL; Smyrniotis, V, 2006) |
| "Failure to recognize the impact of various situations described throughout this work, including the bioavailability due to loss of oral route, due to pharmacokinetics and pharmacodynamics of the various drugs, either in the context of the impaired metabolism or excretion, or in due to pharmacological interactions, conditions a serious risk of subtreatment of pain and consequent impact in terms of quality of life." | 2.61 | [Opioids for Cancer Pain and its Use under Particular Conditions: A Narrative Review]. ( Brás, M; Fragoso, M; Vieira, C, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vieira, C | 1 |
| Brás, M | 1 |
| Fragoso, M | 1 |
| Kostopanagiotou, G | 1 |
| Markantonis, SL | 1 |
| Arkadopoulos, N | 1 |
| Andreadou, I | 1 |
| Charalambidis, G | 1 |
| Chondroudaki, J | 1 |
| Costopanagiotou, C | 1 |
| Smyrniotis, V | 1 |
1 review available for fentanyl and Liver Failure
| Article | Year |
|---|---|
[Opioids for Cancer Pain and its Use under Particular Conditions: A Narrative Review].
Topics: Administration, Oral; Analgesics, Opioid; Buprenorphine; Cancer Pain; Codeine; Deglutition Disorders | 2019 |
1 other study available for fentanyl and Liver Failure
| Article | Year |
|---|---|
The effect of acutely induced hepatic failure on remifentanil and fentanyl blood levels in a pig model.
Topics: Acute Disease; Animals; Female; Fentanyl; Hemodynamics; Liver Failure; Models, Animal; Piperidines; | 2006 |