Page last updated: 2024-10-27

fentanyl and Liver Diseases

fentanyl has been researched along with Liver Diseases in 10 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Liver Diseases: Pathological processes of the LIVER.

Research Excerpts

ExcerptRelevanceReference
"Remifentanil in combination with fentanyl is used less than fentanyl in surgical patients with hepatic impairment or obesity."7.81Remifentanil, fentanyl, or the combination in surgical procedures in the United States: predictors of use in patients with organ impairment or obesity. ( Sclar, DA, 2015)
"Remifentanil in combination with fentanyl is used less than fentanyl in surgical patients with hepatic impairment or obesity."3.81Remifentanil, fentanyl, or the combination in surgical procedures in the United States: predictors of use in patients with organ impairment or obesity. ( Sclar, DA, 2015)
"Therefore, postoperative pain control after OLT should be carefully titrated according to the severity of the liver disease."1.38The relationship between postoperative intravenous patient-controlled fentanyl analgesic requirements and severity of liver disease. ( Gwak, MS; Jang, CH; Kim, GS; Ko, JS; Lee, SK; Shin, YH, 2012)
" Though both volume of distribution and elimination half-life increased in the posttransplantation period, only the decrease in clearance was statistically significant."1.28Effects of cholestatic hepatic disease and chronic renal failure on alfentanil pharmacokinetics in children. ( Brandom, BW; Cook, DR; Davis, JE; Davis, PJ; Scierka, AM; Stiller, RL, 1989)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19906 (60.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's2 (20.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Fung, BM1
Leon, DJ1
Beck, LN1
Tabibian, JH1
Sclar, DA1
Ko, JS1
Shin, YH1
Gwak, MS1
Jang, CH1
Kim, GS1
Lee, SK1
Djurberg, H1
Pothmann Facharzt, W1
Joseph, D1
Tjan, D1
Zuleika, M1
Ferns, S1
Rasheed, A1
Evans, DA1
Bassas, A1
Rietbrock, I2
Manno, E1
Bertoldi, G1
Avalle, M1
Viegas, O1
Stoelting, RK1
Davis, PJ1
Stiller, RL1
Cook, DR1
Brandom, BW1
Davis, JE1
Scierka, AM1
Coeli, L1
Simone, M1
Fogar, R1

Reviews

2 reviews available for fentanyl and Liver Diseases

ArticleYear
Pre-procedural Preparation and Sedation for Gastrointestinal Endoscopy in Patients with Advanced Liver Disease.
    Digestive diseases and sciences, 2022, Volume: 67, Issue:7

    Topics: Conscious Sedation; Endoscopy, Gastrointestinal; Fentanyl; Humans; Hypnotics and Sedatives; Liver Di

2022
[Altered pharmacokinetics of anaesthetic agents in liver disease during anaesthesia and surgery and intensive-care treatment (author's transl)].
    Der Anaesthesist, 1980, Volume: 29, Issue:8

    Topics: Anesthetics; Critical Care; Dose-Response Relationship, Drug; Drug Tolerance; Fentanyl; Hexobarbital

1980

Other Studies

8 other studies available for fentanyl and Liver Diseases

ArticleYear
Remifentanil, fentanyl, or the combination in surgical procedures in the United States: predictors of use in patients with organ impairment or obesity.
    Clinical drug investigation, 2015, Volume: 35, Issue:1

    Topics: Adult; Aged; Analgesics, Opioid; Anesthetics, Intravenous; Drug Therapy, Combination; Female; Fentan

2015
The relationship between postoperative intravenous patient-controlled fentanyl analgesic requirements and severity of liver disease.
    Transplantation proceedings, 2012, Volume: 44, Issue:2

    Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Chi-Square Distribution; Cough; Female; Fentanyl;

2012
Anesthesia care for living-related liver transplantation for infants and children with end-stage liver disease: report of our initial experience.
    Journal of clinical anesthesia, 2002, Volume: 14, Issue:8

    Topics: Adjuvants, Anesthesia; Adult; Anesthesia, Intravenous; Atracurium; Biliary Atresia; Child; Child, Pr

2002
[Anesthesia in severe liver disease. Personal experience with CT 1341].
    Minerva anestesiologica, 1980, Volume: 46, Issue:11

    Topics: Adult; Aged; Alfaxalone Alfadolone Mixture; Fentanyl; Humans; Liver Diseases; Middle Aged

1980
[Pharmacokinetics of intravenous narcotics (barbiturates and fentanyl) anesthesia and intensive care in patients with liver and kidney insufficiency].
    Klinische Anasthesiologie und Intensivtherapie, 1981, Volume: 23

    Topics: Acute Kidney Injury; Adult; Anesthesia, Intravenous; Barbiturates; Critical Care; Fentanyl; Half-Lif

1981
LDH5 changes after cholecystectomy or hysterectomy in patients receiving halothane, enflurane, or fentanyl.
    Anesthesiology, 1979, Volume: 51, Issue:6

    Topics: Adult; Cholecystectomy; Enflurane; Female; Fentanyl; Halothane; Humans; Hysterectomy; Isoenzymes; L-

1979
Effects of cholestatic hepatic disease and chronic renal failure on alfentanil pharmacokinetics in children.
    Anesthesia and analgesia, 1989, Volume: 68, Issue:5

    Topics: Adolescent; Alfentanil; Child; Child, Preschool; Cholestasis; Fentanyl; Humans; Infant; Kidney Failu

1989
[The use of neuroleptoanalgesia in liver disease patients. (Clinical considerations and experimental findings)].
    Acta anaesthesiologica, 1965, Volume: 16

    Topics: Adult; Aged; Anesthesia; Animals; Benperidol; Biliary Tract Diseases; Dogs; Female; Fentanyl; Humans

1965