Page last updated: 2024-10-27

fentanyl and Liver Cirrhosis

fentanyl has been researched along with Liver Cirrhosis in 13 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.

Research Excerpts

ExcerptRelevanceReference
"We found that combining a single dose of IV parecoxib 40 mg with PCA fentanyl is an easy and effective method of acute pain control after major liver resection."9.22Effects of Pre-Existing Liver Disease on Acute Pain Management Using Patient-Controlled Analgesia Fentanyl With Parecoxib After Major Liver Resection: A Retrospective, Pragmatic Study. ( Chen, CL; Cheng, KW; Chiu, YC; Huang, CE; Huang, CJ; Jawan, B; Juang, SE; Lee, YE; Lim, KI; Shih, TH; Wang, CH; Wu, SC; Yang, SC, 2016)
"We found that combining a single dose of IV parecoxib 40 mg with PCA fentanyl is an easy and effective method of acute pain control after major liver resection."5.22Effects of Pre-Existing Liver Disease on Acute Pain Management Using Patient-Controlled Analgesia Fentanyl With Parecoxib After Major Liver Resection: A Retrospective, Pragmatic Study. ( Chen, CL; Cheng, KW; Chiu, YC; Huang, CE; Huang, CJ; Jawan, B; Juang, SE; Lee, YE; Lim, KI; Shih, TH; Wang, CH; Wu, SC; Yang, SC, 2016)
"We aimed to investigate the safety of combined sedation with propofol plus fentanyl in patients with liver cirrhosis during screening esophagogastroduodenoscopy (SEGD) and a secondary prophylaxis for esophageal varices, endoscopic gastrointestinal ligation (EVL)."3.80The safety of combined sedation with propofol plus fentanyl for endoscopy screening and endoscopic variceal ligation in cirrhotic patients. ( Mao, W; Tao, J; Wei, XQ; Wen, ZF; Wu, B; Zhen, FP, 2014)
"The pharmacokinetics of alfentanil were studied in 11 patients with alcoholic cirrhosis and 10 control patients during general anesthesia."3.67Alfentanil pharmacokinetics in patients with cirrhosis. ( Bouffard, Y; Duvaldestin, P; Ferrier, C; Haberer, JP; Levron, JC; Marty, J, 1985)
"Postoperative pain is one of the most important problems that confront surgical patients."2.79Comparison between intravenous patient controlled analgesia and patient controlled epidural analgesia in cirrhotic patients after hepatic resection. ( Abo El-Wafa, HB; Fayed, NA; Gab-Alla, NM; Lotfy, ME; Yassen, KA, 2014)
"Patients with liver cirrhosis frequently undergo diagnostic or therapeutic upper GI endoscopy (UGIE), and the liver disease might impair the metabolism of drugs usually administered for sedation."2.76Sedation during upper GI endoscopy in cirrhotic outpatients: a randomized, controlled trial comparing propofol and fentanyl with midazolam and fentanyl. ( Bonilha, DQ; Brito, JR; Correia, LM; Ferrari, AP; Gomes, GF; Lenz, L; Libera, ED; Nakao, FS; Rohr, MR, 2011)
"This retrospective cohort study of cirrhotic patients undergoing endoscopy from a large academic medical center between 2010 and 2014 examined extensive clinical data including the following: past history, physical findings, laboratory results, and procedural adverse events."1.56Sedation During Endoscopy in Patients with Cirrhosis: Safety and Predictors of Adverse Events. ( Edelson, J; Rockey, DC; Suarez, AL; Zhang, J, 2020)
"We report a 75-year-old man with the liver cirrhosis of Child-Pugh B who underwent nephrectomy."1.34[Combination of spinal and inhalation anesthesia for nephrectomy in a cirrhotic patient]. ( Kano, T; Kono, Y; Sawada, M, 2007)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19903 (23.08)18.7374
1990's1 (7.69)18.2507
2000's2 (15.38)29.6817
2010's5 (38.46)24.3611
2020's2 (15.38)2.80

Authors

AuthorsStudies
Zhang, H1
Yang, L1
Yu, Z1
Li, D1
Li, L1
Li, S1
Yan, J1
Li, X1
Edelson, J1
Suarez, AL1
Zhang, J1
Rockey, DC1
Mao, W1
Wei, XQ1
Tao, J1
Zhen, FP1
Wen, ZF1
Wu, B1
Fayed, NA1
Abo El-Wafa, HB1
Gab-Alla, NM1
Yassen, KA1
Lotfy, ME1
Lim, KI1
Chiu, YC1
Chen, CL1
Wang, CH1
Huang, CJ1
Cheng, KW1
Wu, SC1
Shih, TH1
Yang, SC1
Juang, SE1
Huang, CE1
Jawan, B1
Lee, YE1
Lee, KH1
Nam, SH1
Yoo, SY1
Jung, CW1
Bae, SS1
Lee, JR1
Correia, LM1
Bonilha, DQ1
Gomes, GF1
Brito, JR1
Nakao, FS1
Lenz, L1
Rohr, MR1
Ferrari, AP1
Libera, ED1
Kim, TW1
Harbott, M1
Sawada, M1
Kono, Y1
Kano, T1
Rietbrock, I1
Lluch Fernández, M1
Vallejo Uclés, A1
Vallejo Cantarero, F1
Zurita Castro, F1
Huelva Ramírez, E1
Moreno Carmona, C1
Ferrier, C1
Marty, J1
Bouffard, Y1
Haberer, JP1
Levron, JC1
Duvaldestin, P1
Baden, JM1
Kundomal, YR1
Luttropp, ME1
Maze, M1
Kosek, JC1

Trials

3 trials available for fentanyl and Liver Cirrhosis

ArticleYear
Comparison between intravenous patient controlled analgesia and patient controlled epidural analgesia in cirrhotic patients after hepatic resection.
    Middle East journal of anaesthesiology, 2014, Volume: 22, Issue:5

    Topics: Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, Intravenous; Ane

2014
Effects of Pre-Existing Liver Disease on Acute Pain Management Using Patient-Controlled Analgesia Fentanyl With Parecoxib After Major Liver Resection: A Retrospective, Pragmatic Study.
    Transplantation proceedings, 2016, Volume: 48, Issue:4

    Topics: Acute Pain; Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Drug Therapy, Combination; Femal

2016
Sedation during upper GI endoscopy in cirrhotic outpatients: a randomized, controlled trial comparing propofol and fentanyl with midazolam and fentanyl.
    Gastrointestinal endoscopy, 2011, Volume: 73, Issue:1

    Topics: Analgesics, Opioid; Anesthesia Recovery Period; Bradycardia; Conscious Sedation; Deep Sedation; Endo

2011

Other Studies

10 other studies available for fentanyl and Liver Cirrhosis

ArticleYear
Impact of fentanyl analgesia on the accuracy of HVPG measurements in patients with cirrhosis: a prospective, multicenter study.
    Hepatology communications, 2023, 01-01, Volume: 7, Issue:1

    Topics: Analgesia; Fentanyl; Humans; Liver Cirrhosis; Pain; Propofol; Prospective Studies

2023
Sedation During Endoscopy in Patients with Cirrhosis: Safety and Predictors of Adverse Events.
    Digestive diseases and sciences, 2020, Volume: 65, Issue:4

    Topics: Adjuvants, Anesthesia; Aged; Analgesics, Opioid; Cohort Studies; Conscious Sedation; Endoscopy; Fema

2020
The safety of combined sedation with propofol plus fentanyl for endoscopy screening and endoscopic variceal ligation in cirrhotic patients.
    Journal of digestive diseases, 2014, Volume: 15, Issue:3

    Topics: Adult; Conscious Sedation; Drug Combinations; Endoscopy, Digestive System; Endoscopy, Gastrointestin

2014
Vecuronium requirement during liver transplantation under sevoflurane anesthesia.
    Journal of anesthesia, 2010, Volume: 24, Issue:5

    Topics: Aged; Analysis of Variance; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous;

2010
The use of caudal morphine for pediatric liver transplantation.
    Anesthesia and analgesia, 2004, Volume: 99, Issue:2

    Topics: Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Intravenous; Child, Preschool; Female; Fentanyl

2004
[Combination of spinal and inhalation anesthesia for nephrectomy in a cirrhotic patient].
    Masui. The Japanese journal of anesthesiology, 2007, Volume: 56, Issue:1

    Topics: Aged; Alprostadil; Anesthesia, Inhalation; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Dopa

2007
[Pharmacokinetics of intravenous narcotics (barbiturates and fentanyl) anesthesia and intensive care in patients with liver and kidney insufficiency].
    Klinische Anasthesiologie und Intensivtherapie, 1981, Volume: 23

    Topics: Acute Kidney Injury; Adult; Anesthesia, Intravenous; Barbiturates; Critical Care; Fentanyl; Half-Lif

1981
[Anesthesia and intraoperative treatment in 2 cases of simultaneous liver, pancreas, and kidney transplantation].
    Revista espanola de anestesiologia y reanimacion, 1999, Volume: 46, Issue:5

    Topics: Adult; Anesthesia, General; Cardiomyopathy, Hypertrophic; Diabetes Mellitus, Type 1; Diabetic Nephro

1999
Alfentanil pharmacokinetics in patients with cirrhosis.
    Anesthesiology, 1985, Volume: 62, Issue:4

    Topics: Adult; Aged; Alfentanil; Analgesics; Blood Proteins; Dialysis; Female; Fentanyl; Half-Life; Humans;

1985
Effects of volatile anesthetics or fentanyl on hepatic function in cirrhotic rats.
    Anesthesia and analgesia, 1985, Volume: 64, Issue:12

    Topics: Alanine Transaminase; Anesthetics; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Fenta

1985