fentanyl has been researched along with Laryngismus in 17 studies
Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.
Laryngismus: A disorder in which the adductor muscles of the VOCAL CORDS exhibit increased activity leading to laryngeal spasm. Laryngismus causes closure of the VOCAL FOLDS and airflow obstruction during inspiration.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A large percentage of opioid overdose fatalities involve fentanyl or one of its legal or illegal analogs (F/FAs)." | 5.62 | Wooden Chest syndrome: The atypical pharmacology of fentanyl overdose. ( Ann LeQuang, J; Pergolizzi, JV; Raffa, RB; Vortsman, E; Webster, LR, 2021) |
| " fentanyl affected the number of children who develop postextubation adverse upper airway respiratory events, (upper airway obstruction, laryngospasm) and/or early postoperative hypoxemia." | 5.14 | Presurgical fentanyl vs caudal block and the incidence of adverse respiratory events in children after orchidopexy. ( Bolos, ME; Chuang, AZ; Khalil, SN; Lingadevaru, HS; Maposa, D; Matuszczak, ME, 2009) |
| " During sevoflurane induction, severe hypotension and laryngospasm resulted in cardiac arrest." | 3.77 | Transient cardiac arrest in patient with left ventricular noncompaction (spongiform cardiomyopathy). ( Ito, H; Kawaai, H; Yamazaki, S, 2011) |
| "The incidence of gagging (P = 0." | 2.68 | Comparison of propofol versus thiopentone with midazolam or lidocaine to facilitate laryngeal mask insertion. ( Bapat, P; Jago, RH; Joshi, RN; Young, E, 1996) |
| "A large percentage of opioid overdose fatalities involve fentanyl or one of its legal or illegal analogs (F/FAs)." | 1.62 | Wooden Chest syndrome: The atypical pharmacology of fentanyl overdose. ( Ann LeQuang, J; Pergolizzi, JV; Raffa, RB; Vortsman, E; Webster, LR, 2021) |
| "The incidence of laryngospasm was not reduced when up to two successive doses of 1." | 1.36 | Fentanyl does not reduce the incidence of laryngospasm in children anesthetized with sevoflurane. ( Craig, D; Erb, TO; Frei, FJ; Keller, K; Rosner, GL; von Ungern-Sternberg, BS, 2010) |
| "To compare the incidence of laryngospasm by using halothane-fentanyl anaesthesia and midazolam-remifentanil anaesthesia in paediatric patients undergoing eye surgery." | 1.35 | Reduced incidence of laryngospasm with remifentanil-midazolam anaesthesia compared to halothane-fentanyl. ( Ali, S, 2008) |
| " We characterize the fasting status of patients receiving procedural sedation and analgesia in a pediatric ED and assess the relationship between fasting status and adverse events." | 1.32 | Preprocedural fasting state and adverse events in children undergoing procedural sedation and analgesia in a pediatric emergency department. ( Agrawal, D; Gupta, R; Krauss, B; Manzi, SF, 2003) |
| "We observed chest wall rigidity in 8 patients after low dosage of fentanyl (3-5 microg/kg body weight)." | 1.31 | Fentanyl-induced chest wall rigidity and laryngospasm in preterm and term infants. ( Bartmann, P; Fahnenstich, H; Kau, N; Steffan, J, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (41.18) | 18.2507 |
| 2000's | 5 (29.41) | 29.6817 |
| 2010's | 3 (17.65) | 24.3611 |
| 2020's | 2 (11.76) | 2.80 |
| Authors | Studies |
|---|---|
| Pergolizzi, JV | 2 |
| Dahan, A | 1 |
| Ann LeQuang, J | 2 |
| Raffa, RB | 2 |
| Webster, LR | 1 |
| Vortsman, E | 1 |
| Ali, S | 1 |
| Khalil, SN | 1 |
| Matuszczak, ME | 1 |
| Maposa, D | 1 |
| Bolos, ME | 1 |
| Lingadevaru, HS | 1 |
| Chuang, AZ | 1 |
| Erb, TO | 1 |
| von Ungern-Sternberg, BS | 1 |
| Keller, K | 1 |
| Rosner, GL | 1 |
| Craig, D | 1 |
| Frei, FJ | 1 |
| Yamazaki, S | 1 |
| Ito, H | 1 |
| Kawaai, H | 1 |
| Makkar, JK | 1 |
| Ghai, B | 1 |
| Bhardwaj, N | 1 |
| Wig, J | 1 |
| Agrawal, D | 1 |
| Manzi, SF | 1 |
| Gupta, R | 1 |
| Krauss, B | 1 |
| Young, A | 1 |
| Skinner, TA | 1 |
| Baraka, A | 1 |
| Hadi, NG | 1 |
| Singh, S | 1 |
| Bapat, P | 1 |
| Joshi, RN | 1 |
| Young, E | 1 |
| Jago, RH | 1 |
| van den Bergh, AA | 2 |
| Rozario, CJ | 2 |
| Savva, D | 2 |
| D'Eramo, EM | 1 |
| Fahnenstich, H | 1 |
| Steffan, J | 1 |
| Kau, N | 1 |
| Bartmann, P | 1 |
| Kong, CF | 1 |
| Chew, ST | 1 |
| Ip-Yam, PC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Head Position on Minimum Alveolar Concentration of Endotracheal Intubation（MACEI）of Sevoflurane in Children With Obstructive Airway[NCT03522402] | 38 participants (Anticipated) | Interventional | 2018-01-01 | Enrolling by invitation | |||
| Do Patients Need Pre-Procedural Fasting for Coronary Artery Procedures?[NCT02562638] | 240 participants (Anticipated) | Interventional | 2015-10-31 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for fentanyl and Laryngismus
| Article | Year |
|---|---|
Overdoses due to fentanyl and its analogues (F/FAs) push naloxone to the limit.
Topics: Diaphragm; Dose-Response Relationship, Drug; Fentanyl; Heroin; Humans; Laryngismus; Muscle Rigidity; | 2021 |
3 trials available for fentanyl and Laryngismus
| Article | Year |
|---|---|
Presurgical fentanyl vs caudal block and the incidence of adverse respiratory events in children after orchidopexy.
Topics: Airway Obstruction; Anesthesia, Caudal; Anesthetics, Intravenous; Child; Child, Preschool; Fentanyl; | 2009 |
Comparison of propofol versus thiopentone with midazolam or lidocaine to facilitate laryngeal mask insertion.
Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Cough; Drug Costs; Elective Surgical Procedures | 1996 |
Intravenous opioids reduce airway irritation during induction of anaesthesia with desflurane in adults.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Anesthetics, Inhalation; Cough; Desflurane; Female; F | 2000 |
13 other studies available for fentanyl and Laryngismus
| Article | Year |
|---|---|
Wooden Chest syndrome: The atypical pharmacology of fentanyl overdose.
Topics: Diaphragm; Fentanyl; Heroin; Humans; Laryngismus; Muscle Rigidity; Opiate Overdose; Syndrome; Thorac | 2021 |
Reduced incidence of laryngospasm with remifentanil-midazolam anaesthesia compared to halothane-fentanyl.
Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Drug Therapy, Combination; F | 2008 |
Fentanyl does not reduce the incidence of laryngospasm in children anesthetized with sevoflurane.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Child; Child, Preschool; Dose-Response Relationsh | 2010 |
Transient cardiac arrest in patient with left ventricular noncompaction (spongiform cardiomyopathy).
Topics: Anesthesia, Dental; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Cardiomy | 2011 |
Minimum alveolar concentration of desflurane with fentanyl for laryngeal mask airway removal in anesthetized children.
Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Child; Child, Preschool; Cou | 2012 |
Preprocedural fasting state and adverse events in children undergoing procedural sedation and analgesia in a pediatric emergency department.
Topics: Adjuvants, Anesthesia; Analgesia; Anesthetics, Combined; Child; Child, Preschool; Chloral Hydrate; C | 2003 |
Laryngospasm following extubation in children.
Topics: Analgesics, Opioid; Anesthesia, General; Child; Fentanyl; Humans; Intubation, Intratracheal; Laryngi | 1995 |
Fentanyl-induced laryngospasm following tracheal extubation in a child.
Topics: Adenoidectomy; Child, Preschool; Fentanyl; Humans; Intubation, Intratracheal; Laryngismus; Male; Ton | 1995 |
Fentanyl-induced laryngospasm.
Topics: Analgesics, Opioid; Fentanyl; Humans; Laryngismus | 1996 |
Fentanyl-induced laryngospasm?
Topics: Analgesics, Opioid; Child, Preschool; Fentanyl; Humans; Laryngismus; Male | 1996 |
Fentanyl-induced laryngospasm?
Topics: Analgesics, Opioid; Child, Preschool; Fentanyl; Humans; Laryngismus; Male | 1996 |
Mortality and morbidity with outpatient anesthesia: the Massachusetts experience.
Topics: Aged; Ambulatory Care; Analgesics, Opioid; Anesthesia, Dental; Anesthesia, General; Anesthesia, Loca | 1999 |
Fentanyl-induced chest wall rigidity and laryngospasm in preterm and term infants.
Topics: Fentanyl; Humans; Hypercapnia; Hypoxia; Infant, Newborn; Infant, Premature; Laryngismus; Naloxone; N | 2000 |