Page last updated: 2024-10-27

fentanyl and Intracranial Hypertension

fentanyl has been researched along with Intracranial Hypertension in 10 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Intracranial Hypertension: Increased pressure within the cranial vault. This may result from several conditions, including HYDROCEPHALUS; BRAIN EDEMA; intracranial masses; severe systemic HYPERTENSION; PSEUDOTUMOR CEREBRI; and other disorders.

Research Excerpts

ExcerptRelevanceReference
"Ketamine has traditionally been avoided as an induction agent for tracheal intubation in patients with neurologic conditions at risk for intracranial hypertension due to conflicting data in the literature."8.31Co-administration of Ketamine in Pediatric Patients with Neurologic Conditions at Risk for Intracranial Hypertension. ( Ampah, SB; Beaulieu, F; Francoeur, C; Gajjar, AA; Griffis, H; Heuer, GG; Huh, JW; Kilbaugh, TJ; Kirschen, MP; Lang, SS; Mazandi, VM; Nishisaki, A; Rahman, RK; Storm, PB; Topjian, AA; Tucker, AM; Yuan, I; Zhang, B, 2023)
"To evaluate the clinical effectiveness of bolus-dose fentanyl and midazolam to treat episodic intracranial hypertension in children with severe traumatic brain injury."7.83Fentanyl and Midazolam Are Ineffective in Reducing Episodic Intracranial Hypertension in Severe Pediatric Traumatic Brain Injury. ( Doctor, A; Kharasch, ED; Leonard, JR; Pineda, JA; Wallendorf, MJ; Welch, TP, 2016)
"Ketamine has traditionally been avoided as an induction agent for tracheal intubation in patients with neurologic conditions at risk for intracranial hypertension due to conflicting data in the literature."4.31Co-administration of Ketamine in Pediatric Patients with Neurologic Conditions at Risk for Intracranial Hypertension. ( Ampah, SB; Beaulieu, F; Francoeur, C; Gajjar, AA; Griffis, H; Heuer, GG; Huh, JW; Kilbaugh, TJ; Kirschen, MP; Lang, SS; Mazandi, VM; Nishisaki, A; Rahman, RK; Storm, PB; Topjian, AA; Tucker, AM; Yuan, I; Zhang, B, 2023)
"To evaluate the clinical effectiveness of bolus-dose fentanyl and midazolam to treat episodic intracranial hypertension in children with severe traumatic brain injury."3.83Fentanyl and Midazolam Are Ineffective in Reducing Episodic Intracranial Hypertension in Severe Pediatric Traumatic Brain Injury. ( Doctor, A; Kharasch, ED; Leonard, JR; Pineda, JA; Wallendorf, MJ; Welch, TP, 2016)
"Hydrocephalus is an active distension of the ventricular system of the brain."1.56Anaesthetic management of intracranial hypertension and pregnancy. A case report. ( Campos, MJ; Carreira, C; Norte, G; Órfão, R; Raimundo, A; Sampaio, A, 2020)
"Fentanyl was significantly associated with the most frequent treatment failure."1.43Effectiveness of Pharmacological Therapies for Intracranial Hypertension in Children With Severe Traumatic Brain Injury--Results From an Automated Data Collection System Time-Synched to Drug Administration. ( Balasubramani, GK; Bayir, H; Bell, MJ; Clark, RS; Ferguson, NM; Fink, EL; Kochanek, PM; Shein, SL; Tian, Y; Tyler-Kabara, EC; Wisniewski, SR, 2016)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (10.00)18.2507
2000's0 (0.00)29.6817
2010's7 (70.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Mazandi, VM1
Lang, SS1
Rahman, RK1
Nishisaki, A1
Beaulieu, F1
Zhang, B1
Griffis, H1
Tucker, AM1
Storm, PB1
Heuer, GG1
Gajjar, AA1
Ampah, SB1
Kirschen, MP1
Topjian, AA1
Yuan, I1
Francoeur, C1
Kilbaugh, TJ1
Huh, JW1
Sampaio, A1
Norte, G1
Campos, MJ1
Raimundo, A1
Carreira, C1
Órfão, R1
Colton, K2
Yang, S2
Hu, PF2
Chen, HH2
Bonds, B2
Scalea, TM2
Stein, DM2
Loflin, R1
Koyfman, A1
Stansbury, LG1
Shein, SL1
Ferguson, NM1
Kochanek, PM1
Bayir, H1
Clark, RS1
Fink, EL1
Tyler-Kabara, EC1
Wisniewski, SR1
Tian, Y1
Balasubramani, GK1
Bell, MJ1
Welch, TP1
Wallendorf, MJ1
Kharasch, ED1
Leonard, JR1
Doctor, A1
Pineda, JA1
Tomar, GS1
Goyal, K1
Chandran, R1
Luthra, A1
Chauhan, V1
Kumar, N1
Baidya, DK1
Trikha, A1
Menon, S1
Garg, R1
Hirota, K1
Hashiba, E1
Suzuki, A1
Ishihara, H1
Matsuki, A1

Reviews

1 review available for fentanyl and Intracranial Hypertension

ArticleYear
When used for sedation, does ketamine increase intracranial pressure more than fentanyl or sufentanil?
    Annals of emergency medicine, 2015, Volume: 65, Issue:1

    Topics: Anesthetics, Dissociative; Deep Sedation; Fentanyl; Humans; Hypnotics and Sedatives; Intracranial Hy

2015

Trials

1 trial available for fentanyl and Intracranial Hypertension

ArticleYear
[Changes in epidural pressure during total intravenous anesthesia with propofol, fentanyl and ketamine].
    Masui. The Japanese journal of anesthesiology, 1997, Volume: 46, Issue:9

    Topics: Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intrave

1997

Other Studies

8 other studies available for fentanyl and Intracranial Hypertension

ArticleYear
Co-administration of Ketamine in Pediatric Patients with Neurologic Conditions at Risk for Intracranial Hypertension.
    Neurocritical care, 2023, Volume: 38, Issue:2

    Topics: Analgesics; Child; Fentanyl; Humans; Intracranial Hypertension; Ketamine; Midazolam

2023
Anaesthetic management of intracranial hypertension and pregnancy. A case report.
    Revista espanola de anestesiologia y reanimacion, 2020, Volume: 67, Issue:4

    Topics: Adjuvants, Anesthesia; Adult; Anesthesia; Anesthetics, Inhalation; Cesarean Section; Female; Fentany

2020
Intracranial pressure response after pharmacologic treatment of intracranial hypertension.
    The journal of trauma and acute care surgery, 2014, Volume: 77, Issue:1

    Topics: Adult; Brain Injuries; Critical Care; Documentation; Female; Fentanyl; Humans; Hypnotics and Sedativ

2014
Pharmacologic Treatment Reduces Pressure Times Time Dose and Relative Duration of Intracranial Hypertension.
    Journal of intensive care medicine, 2016, Volume: 31, Issue:4

    Topics: Adult; Barbiturates; Brain Injuries; Dose-Response Relationship, Drug; Female; Fentanyl; Humans; Hyp

2016
Effectiveness of Pharmacological Therapies for Intracranial Hypertension in Children With Severe Traumatic Brain Injury--Results From an Automated Data Collection System Time-Synched to Drug Administration.
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2016, Volume: 17, Issue:3

    Topics: Adolescent; Antihypertensive Agents; Brain Injuries, Traumatic; Cerebrovascular Circulation; Child;

2016
Fentanyl and Midazolam Are Ineffective in Reducing Episodic Intracranial Hypertension in Severe Pediatric Traumatic Brain Injury.
    Critical care medicine, 2016, Volume: 44, Issue:4

    Topics: Adolescent; Brain Injuries; Cerebrovascular Circulation; Child; Child, Preschool; Drug Administratio

2016
Aneurysmal hemorrhage in a pregnant patient with coarctation of aorta: An anesthetic challenge.
    Journal of clinical anesthesia, 2017, Volume: 37

    Topics: Adult; Anesthesia, General; Aortic Coarctation; Craniotomy; Female; Fentanyl; Humans; Intracranial A

2017
Anaesthetic management of emergency caesarean section in a patient with seizures and likely raised intracranial pressure due to tuberculous meningitis.
    Anaesthesia and intensive care, 2011, Volume: 39, Issue:5

    Topics: Adult; Androstanols; Anesthesia, Obstetrical; Anesthetics, Inhalation; Anesthetics, Intravenous; Ant

2011