Page last updated: 2024-10-27

fentanyl and Intracranial Aneurysm

fentanyl has been researched along with Intracranial Aneurysm in 27 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Intracranial Aneurysm: Abnormal outpouching in the wall of intracranial blood vessels. Most common are the saccular (berry) aneurysms located at branch points in CIRCLE OF WILLIS at the base of the brain. Vessel rupture results in SUBARACHNOID HEMORRHAGE or INTRACRANIAL HEMORRHAGES. Giant aneurysms (

Research Excerpts

ExcerptRelevanceReference
"Nimodipine, a calcium channel blocking drug, is used in the treatment of cerebral arterial spasm after subarachnoid haemorrhage due to bleeding from an intracranial aneurysm."9.09The effects of nimodipine on vecuronium-induced neuromuscular blockade. ( Aysel, I; Balcioglu, T; Hepaguşlar, H; Uyar, M, 2000)
"Using fentanyl after surgical clipping for ruptured intracranial aneurysms might decrease headache and produce few adverse effects."7.96Effectiveness of Low-Dose Intravenous Fentanyl for Postoperative Headache Management After Neck Clipping of Ruptured Intracranial Aneurysms. ( Ikeda, G; Ishikawa, E; Matsumaru, Y; Matsumura, A; Nakai, Y; Terakado, T; Uemura, K, 2020)
"The resection of a mycotic aneurysm in a patient with concurrent cardiac valvular disease was carried out successfully using high dose fentanyl-oxygen anesthesia followed by immediate postoperative naloxone reversal."7.66High dose fentanyl-oxygen anesthesia for intracranial mycotic aneurysm surgery: a clinical report. ( Harp, JR; Rosenwasser, RH; Shupak, RC, 1983)
"Nimodipine, a calcium channel blocking drug, is used in the treatment of cerebral arterial spasm after subarachnoid haemorrhage due to bleeding from an intracranial aneurysm."5.09The effects of nimodipine on vecuronium-induced neuromuscular blockade. ( Aysel, I; Balcioglu, T; Hepaguşlar, H; Uyar, M, 2000)
"Using fentanyl after surgical clipping for ruptured intracranial aneurysms might decrease headache and produce few adverse effects."3.96Effectiveness of Low-Dose Intravenous Fentanyl for Postoperative Headache Management After Neck Clipping of Ruptured Intracranial Aneurysms. ( Ikeda, G; Ishikawa, E; Matsumaru, Y; Matsumura, A; Nakai, Y; Terakado, T; Uemura, K, 2020)
"During opiate anesthesia (standardized dosage of fentanyl) for operation of cerebral aneurysms after subarachnoid hemorrhage, different hemodynamic, respiratory, metabolic, and endocrine parameters were determined before (1 in Fig."3.67[Effect of the calcium antagonist nimodipine on hemodynamics, gas exchange and endocrine parameters in opiate anesthesia]. ( Adams, HA; Börner, U; Gips, H; Hempelmann, G; Marck, P; Müller, H; Otto, O, 1987)
"The resection of a mycotic aneurysm in a patient with concurrent cardiac valvular disease was carried out successfully using high dose fentanyl-oxygen anesthesia followed by immediate postoperative naloxone reversal."3.66High dose fentanyl-oxygen anesthesia for intracranial mycotic aneurysm surgery: a clinical report. ( Harp, JR; Rosenwasser, RH; Shupak, RC, 1983)
" To reach an adequate cerebral perfusion pressure (CPP), the norepinephrine dosage was adapted successively."2.73Effects of fentanyl and S(+)-ketamine on cerebral hemodynamics, gastrointestinal motility, and need of vasopressors in patients with intracranial pathologies: a pilot study. ( Bertsch, T; Horn, P; Muench, E; Quintel, M; Schmittner, MD; Vajkoczy, P; Vajkoczy, SL, 2007)
"Twenty-eight consecutive patients with a cerebral aneurysm were subjected to craniotomy in propofol/fentanyl or propofol/remifentanil anesthesia."2.72The effects of 10 degrees reverse Trendelenburg position on subdural intracranial pressure and cerebral perfusion pressure in patients subjected to craniotomy for cerebral aneurysm. ( Cold, GE; Juul, N; Rasmussen, M; Tankisi, A, 2006)
" Furthermore, total drug dosage requirements were measured and compared."2.67[Infusion or repetitive bolus injection? A clinical study of midazolam/fentanyl and diazepam/fentanyl combination anesthesia in neurosurgical operations]. ( Luger, TJ; Mair, P; Morawetz, R; Mutz, N; Stroschneider, E, 1990)
"Alfentanil was very effective in obtunding this response with stable cardiovascular parameters; fentanyl produced a more variable response; and intravenous lignocaine was less satisfactory."2.66Obtunding the sympathetic response to intubation. Experience at 2 minutes after administration of the test agent in patients with cerebral aneurysms. ( Murray, WB; Oosthuizen, JH; Payne, KA, 1988)
"Forty-two patients underwent cerebral aneurysm clipping at our institution in 1991, 35 with a ruptured aneurysm and 7 with an unruptured aneurysm."1.29Total intravenous anesthesia with propofol for burst suppression in cerebral aneurysm surgery: preliminary report of 42 patients. ( de Tribolet, N; Ravussin, P, 1993)
"Atracurium was used to provide muscle relaxation; the level of neuromuscular block and plasma concentrations of atracurium and laudanosine were measured."1.28Anaesthesia for the treatment of a giant cerebral aneurysm under hypothermic circulatory arrest. ( Anderton, JM; Harper, NJ; Thomas, AN, 1990)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19909 (33.33)18.7374
1990's8 (29.63)18.2507
2000's7 (25.93)29.6817
2010's2 (7.41)24.3611
2020's1 (3.70)2.80

Authors

AuthorsStudies
Terakado, T1
Nakai, Y1
Ikeda, G1
Uemura, K1
Matsumaru, Y1
Ishikawa, E1
Matsumura, A1
Bhardwaj, A1
Bhagat, H1
Grover, VK1
Panda, NB1
Jangra, K1
Sahu, S1
Singla, N1
Tomar, GS1
Goyal, K1
Chandran, R1
Luthra, A1
Chauhan, V1
Kumar, N1
Hashimoto, M1
Johkura, K1
Ichikawa, T1
Kojima, A1
Nishimura, S1
Shinonaga, M1
Grabowska-Gaweł, A1
Wiśniewski, J1
Tankisi, A1
Rasmussen, M1
Juul, N1
Cold, GE1
Magni, G1
La Rosa, I1
Gimignani, S1
Melillo, G1
Imperiale, C1
Rosa, G1
Schmittner, MD1
Vajkoczy, SL1
Horn, P1
Bertsch, T1
Quintel, M1
Vajkoczy, P1
Muench, E1
Wins, MH1
Wolff, F1
Askenasy, HM1
Israeli, J1
Shupak, RC1
Rosenwasser, RH1
Harp, JR1
Van Aken, J1
Bilsback, P1
Van der Schueren, M1
Ravussin, P1
de Tribolet, N1
Sahin, A1
Erçelen, O1
Aypar, U1
Erbengi, A1
Dunbar, PJ1
Visco, E1
Lam, AM1
Yamaguchi, S1
Watanabe, K1
Mishio, M1
Okuda, Y1
Kitajima, T1
Aysel, I1
Hepaguşlar, H1
Balcioglu, T1
Uyar, M1
Ozköse, Z1
Yardim, S1
Yurtlu, S1
Doğulu, F1
Kaymaz, M1
Paşaoğlu, A1
Miller, R1
Tausk, HC1
Stark, DC1
Wasnick, JD1
Conlay, LA1
Mair, P1
Mutz, N1
Stroschneider, E1
Luger, TJ1
Morawetz, R1
Launay, F1
Sankowska, A1
Reinmund, M1
Thomas, AN1
Anderton, JM1
Harper, NJ1
Payne, KA1
Murray, WB1
Oosthuizen, JH1
Bachofen, M1
Müller, H1
Marck, P1
Gips, H1
Börner, U1
Otto, O1
Adams, HA1
Hempelmann, G1
Marshall, BM1
Klensch, H1
Gött, U1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of the Analgesic Effects of Scalp Nerve Block and Intravenous Ibuprofen Applications Under the Guidance of Nociception Level Index (NoL) in Patients Undergoing Elective Supratentorial Craniotomy[NCT05763836]Phase 4102 participants (Anticipated)Interventional2022-11-01Recruiting
Continous Intravenous Lidocaine Infusion Intraoperative for Craniotomy Tumor Removal Surgery: Effect to Brain Relaxation, Opioid Consumption and Postoperative Cognitive Status[NCT04773093]Phase 1/Phase 250 participants (Anticipated)Interventional2021-01-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

10 trials available for fentanyl and Intracranial Aneurysm

ArticleYear
Comparison of propofol and desflurane for postanaesthetic morbidity in patients undergoing surgery for aneurysmal SAH: a randomized clinical trial.
    Journal of anesthesia, 2018, Volume: 32, Issue:2

    Topics: Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Blood Pressure; Desflurane; Female; Fentan

2018
[Effects of modified anaesthesia for patients undergoing brain artery aneurysm repair operation].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2004, Volume: 17, Issue:99

    Topics: Anesthesia, General; Anesthetics, Intravenous; Carbon Dioxide; Female; Fentanyl; Humans; Hydrotherap

2004
The effects of 10 degrees reverse Trendelenburg position on subdural intracranial pressure and cerebral perfusion pressure in patients subjected to craniotomy for cerebral aneurysm.
    Journal of neurosurgical anesthesiology, 2006, Volume: 18, Issue:1

    Topics: Anesthesia, General; Anesthetics, Intravenous; Blood Pressure; Cerebrovascular Circulation; Cranioto

2006
Effects of fentanyl and S(+)-ketamine on cerebral hemodynamics, gastrointestinal motility, and need of vasopressors in patients with intracranial pathologies: a pilot study.
    Journal of neurosurgical anesthesiology, 2007, Volume: 19, Issue:4

    Topics: Adult; Aged; Analgesics, Opioid; Anesthetics, Dissociative; Brain Injuries; Cerebrovascular Circulat

2007
The effects of nimodipine on vecuronium-induced neuromuscular blockade.
    European journal of anaesthesiology, 2000, Volume: 17, Issue:6

    Topics: Adjuvants, Anesthesia; Adult; Anesthesia, Inhalation; Anesthetics, Inhalation; Calcium Channel Block

2000
The effects of intravenous fentanyl and lidocaine infiltration on the hemodynamic response to skull pin placement.
    Neurosurgical review, 2001, Volume: 24, Issue:1

    Topics: Adult; Aged; Anesthesia, Intravenous; Anesthesia, Local; Blood Pressure; Bone Nails; Brain Neoplasms

2001
Effect of Innovar, fentanyl and droperidol on the cerebrospinal fluid pressure in neurosurgical patients.
    Canadian Anaesthetists' Society journal, 1975, Volume: 22, Issue:4

    Topics: Adult; Aged; Anesthesia, Intravenous; Atropine; Blood Pressure; Brain Neoplasms; Carbon Dioxide; Cli

1975
[Infusion or repetitive bolus injection? A clinical study of midazolam/fentanyl and diazepam/fentanyl combination anesthesia in neurosurgical operations].
    Anasthesie, Intensivtherapie, Notfallmedizin, 1990, Volume: 25 Suppl 1

    Topics: Adult; Anesthesia, Intravenous; Brain Neoplasms; Craniotomy; Diazepam; Fentanyl; Hemodynamics; Human

1990
Obtunding the sympathetic response to intubation. Experience at 2 minutes after administration of the test agent in patients with cerebral aneurysms.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1988, May-21, Volume: 73, Issue:10

    Topics: Adult; Alfentanil; Anesthesia, Endotracheal; Anesthetics; Blood Pressure; Fentanyl; Humans; Intracra

1988
[Suppression of blood pressure increases during intubation: lidocaine or fentanyl?].
    Der Anaesthesist, 1988, Volume: 37, Issue:3

    Topics: Adolescent; Adult; Aged; Blood Pressure; Brain Neoplasms; Child; Female; Fentanyl; Humans; Hypertens

1988

Other Studies

17 other studies available for fentanyl and Intracranial Aneurysm

ArticleYear
Effectiveness of Low-Dose Intravenous Fentanyl for Postoperative Headache Management After Neck Clipping of Ruptured Intracranial Aneurysms.
    World neurosurgery, 2020, Volume: 134

    Topics: Adult; Aged; Analgesics, Opioid; Aneurysm, Ruptured; Dose-Response Relationship, Drug; Female; Fenta

2020
Aneurysmal hemorrhage in a pregnant patient with coarctation of aorta: An anesthetic challenge.
    Journal of clinical anesthesia, 2017, Volume: 37

    Topics: Adult; Anesthesia, General; Aortic Coarctation; Craniotomy; Female; Fentanyl; Humans; Intracranial A

2017
Conservative treatment of ruptured vertebrobasilar dissecting aneurysm.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2008, Volume: 29, Issue:4

    Topics: Adjuvants, Anesthesia; Aged; Aged, 80 and over; Antihypertensive Agents; Basilar Artery; Bed Rest; B

2008
Early postoperative complications after intracranial surgery: comparison between total intravenous and balanced anesthesia.
    Journal of neurosurgical anesthesiology, 2007, Volume: 19, Issue:4

    Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Combined; Anesthetics, In

2007
Neuroleptanalgesia in carotid artery ligation.
    Acta anaesthesiologica Scandinavica. Supplementum, 1966, Volume: 23

    Topics: Anesthesia, Local; Benperidol; Carotid Arteries; Cerebrovascular Circulation; Fentanyl; Hemostasis;

1966
High dose fentanyl-oxygen anesthesia for intracranial mycotic aneurysm surgery: a clinical report.
    Neurosurgery, 1983, Volume: 13, Issue:2

    Topics: Adult; Anesthesia; Aneurysm, Infected; Female; Fentanyl; Heart Valve Diseases; Humans; Intracranial

1983
Controlled hypotension with fentanyl and halothane in neurosurgery. A clinical evaluation.
    Acta anaesthesiologica Belgica, 1980, Volume: 31 Suppl

    Topics: Acid-Base Equilibrium; Adult; Anesthesia, Inhalation; Fentanyl; Halothane; Humans; Hypotension, Cont

1980
Total intravenous anesthesia with propofol for burst suppression in cerebral aneurysm surgery: preliminary report of 42 patients.
    Neurosurgery, 1993, Volume: 32, Issue:2

    Topics: Anesthesia, General; Anesthesia, Intravenous; Blood Pressure; Carbon Dioxide; Cerebrovascular Circul

1993
Cerebral aneurysm surgery in a patient with phaeochromocytoma.
    European journal of anaesthesiology, 1998, Volume: 15, Issue:3

    Topics: Adrenal Gland Neoplasms; Anesthetics, Inhalation; Anesthetics, Intravenous; Antihypertensive Agents;

1998
Craniotomy procedures are associated with less analgesic requirements than other surgical procedures.
    Anesthesia and analgesia, 1999, Volume: 88, Issue:2

    Topics: Analgesics; Analgesics, Opioid; Anesthesia Recovery Period; Anesthetics, Intravenous; Body Weight; B

1999
Craniotomy procedures are associated with less analgesic requirements than other surgical procedures.
    Anesthesia and analgesia, 1999, Volume: 88, Issue:2

    Topics: Analgesics; Analgesics, Opioid; Anesthesia Recovery Period; Anesthetics, Intravenous; Body Weight; B

1999
Craniotomy procedures are associated with less analgesic requirements than other surgical procedures.
    Anesthesia and analgesia, 1999, Volume: 88, Issue:2

    Topics: Analgesics; Analgesics, Opioid; Anesthesia Recovery Period; Anesthetics, Intravenous; Body Weight; B

1999
Craniotomy procedures are associated with less analgesic requirements than other surgical procedures.
    Anesthesia and analgesia, 1999, Volume: 88, Issue:2

    Topics: Analgesics; Analgesics, Opioid; Anesthesia Recovery Period; Anesthetics, Intravenous; Body Weight; B

1999
[A case of cardiac arrest after torsades de pointes due to prolonged QT interval syndrome possibly associated with subarachnoid hemorrhage].
    Masui. The Japanese journal of anesthesiology, 1999, Volume: 48, Issue:6

    Topics: Anesthesia, General; Anesthetics, Intravenous; Aneurysm, Ruptured; Diuretics; Fatal Outcome; Female;

1999
Induced hypertension for cerebral aneurysm surgery in a patient with carotid occlusive disease.
    Anesthesia and analgesia, 1990, Volume: 70, Issue:3

    Topics: Anesthetics; Arterial Occlusive Diseases; Carotid Artery Diseases; Fentanyl; Humans; Hypertension; I

1990
[Anesthesia for intracranial aneurysms treated by endovascular approach: 31 cases].
    Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1990, Volume: 31, Issue:5

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Catheterization; Child; Clinical Protocols; Female; Fe

1990
Anaesthesia for the treatment of a giant cerebral aneurysm under hypothermic circulatory arrest.
    Anaesthesia, 1990, Volume: 45, Issue:5

    Topics: Adult; Anesthesia, General; Atracurium; Female; Fentanyl; Heart Arrest, Induced; Humans; Hypothermia

1990
[Effect of the calcium antagonist nimodipine on hemodynamics, gas exchange and endocrine parameters in opiate anesthesia].
    Der Anaesthesist, 1987, Volume: 36, Issue:10

    Topics: Anesthesia, General; Cerebrovascular Circulation; Fentanyl; Hemodynamics; Hormones; Humans; Infusion

1987
Neuroleptanesthesia in neurosurgery.
    International anesthesiology clinics, 1973,Fall, Volume: 11, Issue:3

    Topics: Anesthesia, General; Cerebral Angiography; Cerebral Ventriculography; Craniotomy; Droperidol; Electr

1973
[Liquor adrenaline and noradrenaline in surgical stress].
    Klinische Wochenschrift, 1970, Jul-15, Volume: 48, Issue:14

    Topics: Anesthesia, General; Epinephrine; Fentanyl; Halothane; Humans; Intracranial Aneurysm; Norepinephrine

1970