fentanyl has been researched along with Injuries, Leg in 6 studies
Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5 μg/kg intranasal fentanyl in children 4 to 17 years old with acute pain from suspected isolated extremity fractures presenting to an urban Level II pediatric trauma center from December 2015 to November 2016." | 5.24 | Randomized Controlled Feasibility Trial of Intranasal Ketamine Compared to Intranasal Fentanyl for Analgesia in Children with Suspected Extremity Fractures. ( Bryant, KK; Dunn, C; Hogg, M; Moore, CG; Reynolds, SL; Runyon, MS; Studnek, JR; Templin, MA; Walker, KR; Young, JR, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Reynolds, SL | 1 |
| Bryant, KK | 1 |
| Studnek, JR | 1 |
| Hogg, M | 1 |
| Dunn, C | 1 |
| Templin, MA | 1 |
| Moore, CG | 1 |
| Young, JR | 1 |
| Walker, KR | 1 |
| Runyon, MS | 1 |
| Graudins, A | 1 |
| Meek, R | 1 |
| Egerton-Warburton, D | 1 |
| Seith, R | 1 |
| Furness, T | 1 |
| Chapman, R | 1 |
| Farahmand, S | 1 |
| Shiralizadeh, S | 1 |
| Talebian, MT | 1 |
| Bagheri-Hariri, S | 1 |
| Arbab, M | 1 |
| Basirghafouri, H | 1 |
| Saeedi, M | 1 |
| Sedaghat, M | 1 |
| Mirzababai, H | 1 |
| Gaertner, E | 1 |
| Dilovski, K | 1 |
| Bourlon, S | 1 |
| Bistour, L | 1 |
| Pottecher, T | 1 |
| Adams, HA | 1 |
| Russ, W | 1 |
| Börner, U | 1 |
| Gips, H | 1 |
| Hempelmann, G | 1 |
| Oseev, VV | 1 |
| Timofeev, VV | 1 |
| Tsybuliak, GN | 1 |
| Meshcheriakov, AV | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of Sub-dissociative Dose Intranasal Ketamine to Intranasal Fentanyl for Treatment of Moderate to Severe Pain in Pediatric Patients Presenting to the Emergency Department: a Prospective, Randomized, Double-blind Study[NCT02388321] | Phase 4 | 22 participants (Actual) | Interventional | 2015-05-01 | Terminated (stopped due to Patients meeting inclusion criteria was low, and PI went to another institution.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The patient were asked at 30 minutes post administration of analgesia if they experienced any side effects like nausea, vomiting, headache etc. (NCT02388321)
Timeframe: 30 minutes
| Intervention | Participants (Count of Participants) |
|---|---|
| Ketamine | 0 |
| Fentanyl | 0 |
An 11 point Likert Visual Analog Scale with 0 being no pain, 5 being moderate pain and 10 being very severe pain was verbally administered to the patient at 30 minutes post administration of analgesia. (NCT02388321)
Timeframe: 30 minutes
| Intervention | units on a scale (Mean) |
|---|---|
| Ketamine | 3.36 |
| Fentanyl | 2.09 |
4 trials available for fentanyl and Injuries, Leg
| Article | Year |
|---|---|
Randomized Controlled Feasibility Trial of Intranasal Ketamine Compared to Intranasal Fentanyl for Analgesia in Children with Suspected Extremity Fractures.
Topics: Acute Pain; Administration, Intranasal; Adolescent; Analgesics; Arm Injuries; Child; Child, Preschoo | 2017 |
The PICHFORK (Pain InCHildren Fentanyl OR Ketamine) trial comparing the efficacy of intranasal ketamine and fentanyl in the relief of moderate to severe pain in children with limb injuries: study protocol for a randomized controlled trial.
Topics: Administration, Intranasal; Adolescent; Age Factors; Analgesics; Analgesics, Opioid; Arm Injuries; C | 2013 |
Nebulized fentanyl vs intravenous morphine for ED patients with acute limb pain: a randomized clinical trial.
Topics: Acute Pain; Administration, Inhalation; Adult; Analgesics, Opioid; Arm Injuries; Double-Blind Method | 2014 |
[Effect of premedication and fentanyl administration on the endocrine stress reaction during halothane anesthesia].
Topics: Adolescent; Adult; Anesthesia, Inhalation; Atropine; Diazepam; Endocrine Glands; Fentanyl; Halothane | 1987 |
2 other studies available for fentanyl and Injuries, Leg
| Article | Year |
|---|---|
[Locoregional anesthesia of the lower limb at admission of a polytrauma patient with a leg fracture].
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Fentanyl; Fractures, Bone; Humans; Leg Injuries; | 1998 |
[Initial experience in neuroleptoanalgesia in the surgery of injuries].
Topics: Adolescent; Adult; Amputation, Surgical; Arm Injuries; Benperidol; Female; Fentanyl; Fractures, Bone | 1968 |