fentanyl has been researched along with Infant, Premature, Diseases in 18 studies
Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.
Infant, Premature, Diseases: Diseases that occur in PREMATURE INFANTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In very preterm infants on mechanical ventilation, continuous fentanyl infusion plus open-label boluses of fentanyl does not reduce prolonged pain, but does reduce acute pain and increase side effects compared with open-label boluses of fentanyl alone." | 9.17 | Efficacy and safety of continuous infusion of fentanyl for pain control in preterm newborns on mechanical ventilation. ( Ancora, G; Faldella, G; Garetti, E; Lago, P; Mastrocola, M; Merazzi, D; Pierantoni, L; Pirelli, A, 2013) |
| "In very preterm infants on mechanical ventilation, continuous fentanyl infusion plus open-label boluses of fentanyl does not reduce prolonged pain, but does reduce acute pain and increase side effects compared with open-label boluses of fentanyl alone." | 5.17 | Efficacy and safety of continuous infusion of fentanyl for pain control in preterm newborns on mechanical ventilation. ( Ancora, G; Faldella, G; Garetti, E; Lago, P; Mastrocola, M; Merazzi, D; Pierantoni, L; Pirelli, A, 2013) |
| "Mean fentanyl doses were 5." | 1.36 | Anesthetic technique and postoperative outcome in preterm infants undergoing PDA closure. ( Barrington, K; Janvier, A; Lavoie, J; Martinez, JL, 2010) |
| " Elimination half-life was 6-32 hr (mean +/- SD, 17." | 1.27 | Fentanyl pharmacokinetics and hemodynamic effects in preterm infants during ligation of patent ductus arteriosus. ( Collins, C; Crean, P; Klein, J; Koren, G; MacLeod, SM; Roy, WL, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (38.89) | 18.7374 |
| 1990's | 4 (22.22) | 18.2507 |
| 2000's | 2 (11.11) | 29.6817 |
| 2010's | 5 (27.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Qiu, J | 1 |
| Zhao, L | 1 |
| Yang, Y | 1 |
| Zhang, JH | 1 |
| Feng, Y | 1 |
| Cheng, R | 1 |
| Ancora, G | 1 |
| Lago, P | 1 |
| Garetti, E | 1 |
| Pirelli, A | 1 |
| Merazzi, D | 1 |
| Mastrocola, M | 1 |
| Pierantoni, L | 1 |
| Faldella, G | 1 |
| van den Anker, JN | 1 |
| Arabin, B | 1 |
| Kuizenga, K | 1 |
| van Zoeren, D | 1 |
| Zveren, DV | 1 |
| Eyck, JV | 1 |
| Eventov-Friedman, S | 1 |
| Rozin, I | 1 |
| Shinwell, ES | 1 |
| Janvier, A | 1 |
| Martinez, JL | 1 |
| Barrington, K | 1 |
| Lavoie, J | 1 |
| Anand, KJ | 2 |
| Sippell, WG | 2 |
| Aynsley-Green, A | 2 |
| Oka, N | 2 |
| Fukumitsu, K | 2 |
| Nishimura, M | 2 |
| Tachimori, Y | 2 |
| Takeuchi, T | 1 |
| Yagihara, T | 1 |
| Kishimoto, H | 1 |
| Nakada, T | 1 |
| Okada, T | 1 |
| Kawahara, F | 1 |
| Itoh, T | 1 |
| Imura, K | 1 |
| Kamata, S | 1 |
| Lemmen, RJ | 1 |
| Semmekrot, BA | 1 |
| Lindemann, R | 1 |
| Colditz, PB | 1 |
| Goldstein, RF | 1 |
| Brazy, JE | 1 |
| Collins, C | 1 |
| Koren, G | 1 |
| Crean, P | 1 |
| Klein, J | 1 |
| Roy, WL | 1 |
| MacLeod, SM | 1 |
| Hickey, PR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Safety of Continuous Infusion of Fentanyl for Pain Control in Preterm Newborn on Mechanical Ventilation[NCT00571636] | Phase 3 | 128 participants (Anticipated) | Interventional | 2007-12-31 | Completed | ||
| Correlation Between Blood Pressure, Heart Rate and Plasma Corticotropin, Cortisol Under Surgical Skin Incision[NCT03892538] | 134 participants (Actual) | Observational | 2018-10-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for fentanyl and Infant, Premature, Diseases
| Article | Year |
|---|---|
Management of pain in the newborn infant.
Topics: Analgesics; Analgesics, Opioid; Fentanyl; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infant | 1991 |
4 trials available for fentanyl and Infant, Premature, Diseases
| Article | Year |
|---|---|
Effects of fentanyl for pain control and neuroprotection in very preterm newborns on mechanical ventilation.
Topics: Double-Blind Method; Electroencephalography; Female; Fentanyl; Gestational Age; Humans; Infant; Infa | 2019 |
Efficacy and safety of continuous infusion of fentanyl for pain control in preterm newborns on mechanical ventilation.
Topics: Analgesics, Opioid; Double-Blind Method; Female; Fentanyl; Follow-Up Studies; Humans; Infant, Newbor | 2013 |
Randomised trial of fentanyl anaesthesia in preterm babies undergoing surgery: effects on the stress response.
Topics: Anesthesia, General; Blood Glucose; Clinical Trials as Topic; Curare; Ductus Arteriosus, Patent; Fen | 1987 |
Randomised trial of fentanyl anaesthesia in preterm babies undergoing surgery: effects on the stress response.
Topics: Anesthesia, General; Blood Glucose; Clinical Trials as Topic; Curare; Ductus Arteriosus, Patent; Fen | 1987 |
13 other studies available for fentanyl and Infant, Premature, Diseases
| Article | Year |
|---|---|
Treating pain in newborn infants: navigating between Scylla and Charybdis.
Topics: Analgesics, Opioid; Female; Fentanyl; Humans; Infant, Premature, Diseases; Male; Pain; Respiration, | 2013 |
Long-term epidural block treatment in patients with early threatening preterm delivery and vaginal fetal engagement.
Topics: Adjuvants, Anesthesia; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Local; Apgar Scor | 2008 |
Case of chest-wall rigidity in a preterm infant caused by prenatal fentanyl administration.
Topics: Cesarean Section; Female; Fentanyl; Humans; Infant, Newborn; Infant, Premature, Diseases; Muscle Rig | 2010 |
Anesthetic technique and postoperative outcome in preterm infants undergoing PDA closure.
Topics: Anesthesia, General; Anesthetics, Intravenous; Ductus Arteriosus, Patent; Female; Fentanyl; Humans; | 2010 |
Pediatric emergency medicine: legal briefs.
Topics: Acidosis; Administration, Cutaneous; Adult; Asphyxia; Brain Damage, Chronic; Burns, Chemical; Child; | 2007 |
[Anesthetic management for ligation of patent ductus arteriosus in premature infant].
Topics: Anesthesia; Ductus Arteriosus, Patent; Fentanyl; Humans; Infant, Newborn; Infant, Premature, Disease | 1984 |
[Anesthetic management of necrotizing enterocolitis in very small premature infants--report of three cases].
Topics: Anesthesia; Enterocolitis, Pseudomembranous; Fentanyl; Humans; Infant, Newborn; Infant, Premature, D | 1984 |
Muscle rigidity causing life-threatening hypercapnia following fentanyl administration in a premature infant.
Topics: Analgesics, Opioid; Anesthetics, Intravenous; Fentanyl; Humans; Hypercapnia; Infant, Newborn; Infant | 1996 |
Respiratory muscle rigidity in a preterm infant after use of fentanyl during Caesarean section.
Topics: Adult; Analgesia, Obstetrical; Analgesics, Opioid; Cesarean Section; Female; Fentanyl; Humans; Infan | 1998 |
Narcotic sedation stabilizes arterial blood pressure fluctuations in sick premature infants.
Topics: Blood Pressure; Conscious Sedation; Fentanyl; Humans; Infant, Newborn; Infant, Premature, Diseases; | 1991 |
Pain, anaesthesia, and babies.
Topics: Anesthesia; Fentanyl; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature, Disease | 1987 |
Fentanyl pharmacokinetics and hemodynamic effects in preterm infants during ligation of patent ductus arteriosus.
Topics: Anesthesia, Intravenous; Blood Pressure; Ductus Arteriosus, Patent; Female; Fentanyl; Heart Rate; He | 1985 |
Intraoperative tension pneumopericardium with tamponade after ligation of patent ductus arteriosus in a premature neonate.
Topics: Anesthesia; Cardiac Tamponade; Ductus Arteriosus, Patent; Fentanyl; Humans; Infant, Newborn; Infant, | 1986 |