fentanyl has been researched along with Hypoventilation in 14 studies
Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.
Hypoventilation: A reduction in the amount of air entering the pulmonary alveoli.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The object of this study was the use of naloxone to correct hypoventilation related to the use of morphinomimetics without suppressing the analgesic effect of these agents." | 5.04 | [Antagonistic effects of naloxone against morphinomimetic agents. Apropos of 10 cases in gynecologic surgery]. ( Jobard, J; Lallia, A; Maestracci, P; Orth, MF, 1978) |
| " Adult male Swiss Webster mice were administered fluorinated regioisomers of fentanyl, butyrylfentantyl and valerylfentanyl, and compared to MOR standards including morphine, buprenorphine, and fentanyl to determine if they would elicit prototypical opioid-like effects including hyperlocomotion (open-field test), antinociception (warm-water tail-withdrawal test), and hypoventilation (whole-body plethysmography test)." | 4.31 | Fentanyl analog structure-activity relationships demonstrate determinants of diverging potencies for antinociception and respiratory depression. ( Bassman, JR; Beardsley, PM; Hassanien, SH; Holt, MC; Iula, DM; Layle, NK; Stevens, DL; Varshneya, NB, 2023) |
| "The effect of a high epidural block on the catecholamine response to hypoventilation was studied in six unanesthetized dogs given intravenous sufentanil (15 micrograms." | 3.68 | Epidural anaesthesia attenuates the catecholamine response to hypoventilation. ( Arcario, TJ; Bacon, GS; Cress, LW; Lineberry, PJ; Stevens, RA, 1990) |
| "Fentanyl was continued at the designated rate through the initial postoperative phase." | 2.71 | Effect-site concentration of propofol for recovery of consciousness is virtually independent of fentanyl effect-site concentration. ( Iwakiri, H; Matsukawa, T; Nagata, O; Ozaki, M; Sessler, DI, 2003) |
| "High midazolam dose was associated with lower IPI levels during the procedure." | 1.42 | The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children. ( Adiv, OE; Garah, J; Rosen, I; Shaoul, R, 2015) |
| "Airway obstruction was more predictive of abnormal blood gas values than was hypoventilation." | 1.29 | Respiratory effects of a balanced anesthetic technique--revisited fifteen years later. ( Campbell, RL; Saxen, MA, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (35.71) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 3 (21.43) | 2.80 |
| Authors | Studies |
|---|---|
| Varshneya, NB | 2 |
| Hassanien, SH | 2 |
| Holt, MC | 2 |
| Stevens, DL | 2 |
| Layle, NK | 2 |
| Bassman, JR | 2 |
| Iula, DM | 2 |
| Beardsley, PM | 2 |
| Switzer, AR | 1 |
| Beland, B | 1 |
| Sarna, JR | 1 |
| Walzak, A | 1 |
| Pfeffer, G | 1 |
| Garah, J | 1 |
| Adiv, OE | 1 |
| Rosen, I | 1 |
| Shaoul, R | 1 |
| Iwakiri, H | 1 |
| Nagata, O | 1 |
| Matsukawa, T | 1 |
| Ozaki, M | 1 |
| Sessler, DI | 1 |
| Owen-Falkenberg, AP | 1 |
| Bernstein, KJ | 1 |
| Campbell, RL | 1 |
| Saxen, MA | 1 |
| Haberer, JP | 1 |
| Maestracci, P | 1 |
| Orth, MF | 1 |
| Lallia, A | 1 |
| Jobard, J | 1 |
| Stevens, RA | 1 |
| Lineberry, PJ | 1 |
| Arcario, TJ | 1 |
| Bacon, GS | 1 |
| Cress, LW | 1 |
| Alexander, GD | 1 |
| Goldrath, M | 1 |
| Brown, EM | 1 |
| Smiler, BG | 1 |
| Podlesch, I | 1 |
| Klieser, HP | 1 |
| Rabanus, T | 1 |
| Anshelevich, IuV | 1 |
| Tiruma, BIa | 1 |
| Zveĭnietse, RA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Importance of Integrated Pulmonary Index in Pediatric Patients Undergoing Bronchoscopy Procedures Under Sedation[NCT05137587] | 60 participants (Actual) | Interventional | 2022-09-01 | Completed | |||
| Comparison of Efficacy and Safety of the Postoperative Analgesia Methods for Supratentorial Craniotomy by Integrated Pulmonary Index (IPI)[NCT02929147] | Phase 4 | 90 participants (Anticipated) | Interventional | 2016-11-30 | Not yet recruiting | ||
| Importance of Integrated Pulmonary Index in Pediatric Patients Undergoing Endoscopy Procedures Under Sedation[NCT05137574] | 60 participants (Actual) | Interventional | 2021-05-10 | Completed | |||
| Comparison of Three Different Pain and Anxiety Reducing Methods in Adult Patients Undergoing Bone Marrow Puncture[NCT00188227] | Phase 4 | 748 participants | Interventional | 2001-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for fentanyl and Hypoventilation
| Article | Year |
|---|---|
Effect-site concentration of propofol for recovery of consciousness is virtually independent of fentanyl effect-site concentration.
Topics: Adult; Anesthesia Recovery Period; Anesthetics, Intravenous; Atropine; Bradycardia; Female; Fentanyl | 2003 |
[Antagonistic effects of naloxone against morphinomimetic agents. Apropos of 10 cases in gynecologic surgery].
Topics: Adult; Clinical Trials as Topic; Consciousness; Drug Evaluation; Female; Fentanyl; Genital Diseases, | 1978 |
12 other studies available for fentanyl and Hypoventilation
| Article | Year |
|---|---|
Respiratory depressant effects of fentanyl analogs are opioid receptor-mediated.
Topics: Animals; Fentanyl; Hypoventilation; Male; Mice; Molecular Structure; Naloxone; Narcotic Antagonists; | 2022 |
Fentanyl analog structure-activity relationships demonstrate determinants of diverging potencies for antinociception and respiratory depression.
Topics: Analgesics, Opioid; Animals; Fentanyl; Hypoventilation; Male; Mice; Morphine; Naltrexone; Receptors, | 2023 |
Fentanyl Overdose Causing Hippocampal Ischaemia Followed by Delayed Leukoencephalopathy.
Topics: Analgesics, Opioid; Brain Ischemia; Disease Progression; Fentanyl; Hippocampus; Humans; Hypoventilat | 2020 |
The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children.
Topics: Adolescent; Algorithms; Anesthetics, Intravenous; Capnography; Child; Child, Preschool; Conscious Se | 2015 |
The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children.
Topics: Adolescent; Algorithms; Anesthetics, Intravenous; Capnography; Child; Child, Preschool; Conscious Se | 2015 |
The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children.
Topics: Adolescent; Algorithms; Anesthetics, Intravenous; Capnography; Child; Child, Preschool; Conscious Se | 2015 |
The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children.
Topics: Adolescent; Algorithms; Anesthetics, Intravenous; Capnography; Child; Child, Preschool; Conscious Se | 2015 |
The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children.
Topics: Adolescent; Algorithms; Anesthetics, Intravenous; Capnography; Child; Child, Preschool; Conscious Se | 2015 |
The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children.
Topics: Adolescent; Algorithms; Anesthetics, Intravenous; Capnography; Child; Child, Preschool; Conscious Se | 2015 |
The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children.
Topics: Adolescent; Algorithms; Anesthetics, Intravenous; Capnography; Child; Child, Preschool; Conscious Se | 2015 |
The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children.
Topics: Adolescent; Algorithms; Anesthetics, Intravenous; Capnography; Child; Child, Preschool; Conscious Se | 2015 |
The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children.
Topics: Adolescent; Algorithms; Anesthetics, Intravenous; Capnography; Child; Child, Preschool; Conscious Se | 2015 |
[Doxapram hydrochloride. Treatment of postoperative hypoventilation caused by fentanyl].
Topics: Doxapram; Female; Fentanyl; Humans; Hypoventilation; Middle Aged; Postoperative Complications | 1980 |
Inappropriate use of transdermal fentanyl for acute postoperative pain.
Topics: Acute Disease; Administration, Cutaneous; Chronic Disease; Contraindications; Fentanyl; Humans; Hypo | 1994 |
Respiratory effects of a balanced anesthetic technique--revisited fifteen years later.
Topics: Airway Obstruction; Anesthesia, Dental; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, I | 1994 |
[Premedication and sedation complications during ophthalmic anesthesia].
Topics: Adjuvants, Anesthesia; Alfentanil; Analgesics, Opioid; Anesthesia; Anesthesia, Conduction; Anesthesi | 2000 |
Epidural anaesthesia attenuates the catecholamine response to hypoventilation.
Topics: Anesthesia, Epidural; Anesthesia, Intravenous; Anesthetics; Animals; Blood Pressure; Carbon Dioxide; | 1990 |
Outpatient laparoscopic sterilization under lcoal anesthesia.
Topics: Acidosis, Respiratory; Ambulatory Care; Anesthesia, Local; Blood Gas Analysis; Diazepam; Female; Fen | 1973 |
[Measures for the sedation of uncooperative and anxious patients in dental practice].
Topics: Anesthesia, Dental; Anthracenes; Anxiety; Atropine; Dental Care; Diazepam; Droperidol; Drug Therapy, | 1974 |
[Use of fentanyl in clinical therapeutic practice].
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Fentanyl; Humans; Hypotension; Hypoventilation; | 1972 |