fentanyl has been researched along with Hypothermia in 26 studies
Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.
Hypothermia: Lower than normal body temperature, especially in warm-blooded animals.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The results of the present study confirm our hypothesis that premedication with droperidol affects perioperative hypothermia." | 9.09 | IM droperidol as premedication attenuates intraoperative hypothermia. ( Matsukawa, T; Saito, Y; Sakura, S; Shido, A; Toyota, K, 2001) |
| "These findings suggest that xylazine exacerbates the life-threatening effects of opioids, proposing worsened brain hypoxia as the mechanism contributing to xylazine-positive opioid-overdose deaths." | 8.31 | Xylazine effects on opioid-induced brain hypoxia. ( Choi, S; Irwin, MR; Kiyatkin, EA, 2023) |
| "The aim of this study was to assess the safety of fentanyl analgosedation during therapeutic hypothermia, by evaluating severe adverse effects and possible correlation with the neurodevelopmental outcome." | 8.12 | Fentanyl analgesia in asphyxiated newborns treated with therapeutic hypothermia. ( Bedetti, L; Berardi, A; Della Casa, E; Ferrari, F; Garetti, E; Guidotti, I; Iughetti, L; Lago, P; Lucaccioni, L; Lugli, L; Pugliese, M; Roversi, MF; Spada, C, 2022) |
| "Therapeutic hypothermia may alter the required dosage of analgesics and sedatives, but no data are available on the effects of mild hypothermia on plasma fentanyl concentration during continuous, long-term administration." | 7.73 | The effect of mild hypothermia on plasma fentanyl concentration and biotransformation in juvenile pigs. ( Bauer, R; Fritz, HG; Holzmayr, M; Lupp, A; Moeritz, KU; Walter, B, 2005) |
| "Intrathecal morphine can produce hypothermia in animals." | 7.73 | Hypothermia after cesarean delivery and its reversal with lorazepam. ( Hess, PE; Snowman, CE; Wang, J, 2005) |
| " Cardiopulmonary instability was more common, and hypothermia was less common in the sedation groups of pentazocine/midazolam and fentanyl/midazolam, compared to the general anesthesia group of air/oxygen/sevoflurane (AOS)." | 5.41 | Safety profile of anesthetic modalities during laser treatment for retinopathy of prematurity: a systematic review. ( Arvanitaki, Z; Gavriilidou, A; Haidich, AB; Mataftsi, A; Seliniotaki, AK; Ziakas, N, 2023) |
| " Following induction of anesthesia, normothermia was maintained in dogs that were treated with a fentanyl patch (F-NORM) or sham patch (C-NORM), or hypothermia was maintained in dogs that were treated with a fentanyl patch (F-HYPO) or sham patch (C-HYPO)." | 5.12 | Effect of transdermally administered fentanyl on minimum alveolar concentration of isoflurane in normothermic and hypothermic dogs. ( Hosgood, G; Pettifer, GR; Wilson, D, 2006) |
| "The results of the present study confirm our hypothesis that premedication with droperidol affects perioperative hypothermia." | 5.09 | IM droperidol as premedication attenuates intraoperative hypothermia. ( Matsukawa, T; Saito, Y; Sakura, S; Shido, A; Toyota, K, 2001) |
| "These findings suggest that xylazine exacerbates the life-threatening effects of opioids, proposing worsened brain hypoxia as the mechanism contributing to xylazine-positive opioid-overdose deaths." | 4.31 | Xylazine effects on opioid-induced brain hypoxia. ( Choi, S; Irwin, MR; Kiyatkin, EA, 2023) |
| "The aim of this study was to assess the safety of fentanyl analgosedation during therapeutic hypothermia, by evaluating severe adverse effects and possible correlation with the neurodevelopmental outcome." | 4.12 | Fentanyl analgesia in asphyxiated newborns treated with therapeutic hypothermia. ( Bedetti, L; Berardi, A; Della Casa, E; Ferrari, F; Garetti, E; Guidotti, I; Iughetti, L; Lago, P; Lucaccioni, L; Lugli, L; Pugliese, M; Roversi, MF; Spada, C, 2022) |
| "Therapeutic hypothermia may alter the required dosage of analgesics and sedatives, but no data are available on the effects of mild hypothermia on plasma fentanyl concentration during continuous, long-term administration." | 3.73 | The effect of mild hypothermia on plasma fentanyl concentration and biotransformation in juvenile pigs. ( Bauer, R; Fritz, HG; Holzmayr, M; Lupp, A; Moeritz, KU; Walter, B, 2005) |
| "Intrathecal morphine can produce hypothermia in animals." | 3.73 | Hypothermia after cesarean delivery and its reversal with lorazepam. ( Hess, PE; Snowman, CE; Wang, J, 2005) |
| "We have examined the effects of the psychostimulant d-amphetamine and the neuroleptic haloperidol on hypothermia induced by intraperitoneal injection of the centrally penetrating opioids morphine, fentanyl and sufentanil and the peripherally acting opioid loperamide." | 3.72 | Morphine and d-amphetamine nullify each others' hypothermic effects in mice. ( Baker, A; Meert, T, 2003) |
| "To determine whether moderate hypothermia during 4 hours of anesthesia with isoflurane substantially affects serum concentrations of transdermally administered fentanyl in the perianesthetic period in cats." | 3.72 | The effect of rectal temperature on perianesthetic serum concentrations of transdermally administered fentanyl in cats anesthetized with isoflurane. ( Hosgood, G; Pettifer, GR, 2003) |
| "Because hypothermia is associated with adverse clinical outcomes, it is important to recognize predictors of hypothermia and to monitor and control body temperature in patients at risk." | 2.69 | Predictors of hypothermia during spinal anesthesia. ( Barnes, RA; Cattaneo, CG; El-Rahmany, HK; Frank, SM, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (23.08) | 18.7374 |
| 1990's | 4 (15.38) | 18.2507 |
| 2000's | 10 (38.46) | 29.6817 |
| 2010's | 3 (11.54) | 24.3611 |
| 2020's | 3 (11.54) | 2.80 |
| Authors | Studies |
|---|---|
| Lugli, L | 1 |
| Spada, C | 1 |
| Garetti, E | 1 |
| Guidotti, I | 1 |
| Roversi, MF | 1 |
| Della Casa, E | 1 |
| Bedetti, L | 1 |
| Lucaccioni, L | 1 |
| Pugliese, M | 1 |
| Ferrari, F | 1 |
| Iughetti, L | 1 |
| Lago, P | 1 |
| Berardi, A | 1 |
| Gavriilidou, A | 1 |
| Seliniotaki, AK | 1 |
| Arvanitaki, Z | 1 |
| Ziakas, N | 1 |
| Haidich, AB | 1 |
| Mataftsi, A | 1 |
| Choi, S | 1 |
| Irwin, MR | 1 |
| Kiyatkin, EA | 1 |
| Alparslan, V | 1 |
| Kus, A | 1 |
| Hosten, T | 1 |
| Ertargin, M | 1 |
| Ozdamar, D | 1 |
| Toker, K | 1 |
| Solak, M | 1 |
| Bergh, MS | 1 |
| Bogen, IL | 1 |
| Garibay, N | 1 |
| Baumann, MH | 1 |
| Lista, F | 1 |
| Doherty, CD | 1 |
| Backstein, RM | 1 |
| Ahmad, J | 1 |
| Baker, A | 1 |
| Meert, T | 1 |
| Sakamoto, T | 1 |
| Kawaguchi, M | 1 |
| Kakimoto, M | 1 |
| Inoue, S | 1 |
| Takahashi, M | 1 |
| Furuya, H | 1 |
| FAVA, E | 1 |
| QUERCI, M | 2 |
| MARCHIARO, G | 1 |
| RUGGERINI, R | 1 |
| ZECCA, C | 1 |
| MOLINAROLI, P | 1 |
| TARQUINI, A | 1 |
| CORTIS, B | 1 |
| SANNA, O | 1 |
| Pettifer, GR | 2 |
| Hosgood, G | 2 |
| Fritz, HG | 1 |
| Holzmayr, M | 1 |
| Walter, B | 1 |
| Moeritz, KU | 1 |
| Lupp, A | 1 |
| Bauer, R | 1 |
| Preisman, S | 1 |
| Marks, R | 1 |
| Nahtomi-Shick, O | 1 |
| Sidi, A | 1 |
| Hess, PE | 1 |
| Snowman, CE | 1 |
| Wang, J | 1 |
| Wilson, D | 1 |
| Wishaw, K | 1 |
| Okada, Y | 1 |
| Powis, M | 1 |
| McEwan, A | 1 |
| Pierro, A | 1 |
| Frank, SM | 1 |
| El-Rahmany, HK | 1 |
| Cattaneo, CG | 1 |
| Barnes, RA | 1 |
| Suyama, H | 1 |
| Tsuno, S | 1 |
| Takeyoshi, S | 1 |
| Takiyama, R | 1 |
| Toyota, K | 1 |
| Sakura, S | 1 |
| Saito, Y | 1 |
| Shido, A | 1 |
| Matsukawa, T | 1 |
| Rose, DK | 1 |
| Cohen, MM | 1 |
| Soutter, DI | 1 |
| Jenkins, I | 1 |
| Karliczek, G | 1 |
| de Geus, F | 1 |
| Brenken, U | 1 |
| Johnson, MD | 1 |
| Sevarino, FB | 1 |
| Lema, MJ | 1 |
| Linko, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Standard Normothermia Protocol On Surgical Site Infections: Randomized Controlled Trial[NCT02961244] | 118 participants (Actual) | Interventional | 2013-06-30 | Completed | |||
| The Effect Of Forced Air Warming Used For Different Body Parts During Caseraen Section On Maternal Hypothermia, Shivering, Thermal Comfort, Apgar Score And Breastfeeding: Randomized Controlled Trial[NCT04667000] | 35 participants (Anticipated) | Interventional | 2021-05-01 | Active, not recruiting | |||
| Efficacy of a Thermal Insulation System in Inadvertent Hypothermia and Perioperative Comfort[NCT05131568] | 124 participants (Actual) | Interventional | 2018-10-15 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Within the surgery day, from patient bed through the operating room to PACU or ICU or back to patient bed.~With these results our intervention group's maintaining normothermia rates were higher respectively. ( p=0.001) For each patients around 11 temperature measurement had been made according to the operation time . If any measurement of any patients was <36 ºC , that patient accepted as hypothermic. (Failure to maintain normothermia)" (NCT02961244)
Timeframe: Surgery day
| Intervention | Participants (Count of Participants) |
|---|---|
| Control Group | 7 |
| Intervention Group | 26 |
"Within the postoperative 30 days, if there is purulent exudate or nonpurulent but culture was pozitive, we accepted them as Surgical Site Infection (SSI) diagnosed.~All patients were made enough incision wide to explore their entire abdomen defined as Major Abdominal Surgery .~With this results between two groups intervention group had lesser rates of SSI respectively( (p=0.045 Mann Whitney U, n<30), (p=0.044 chi-square )" (NCT02961244)
Timeframe: Postoperative 30 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Control Group | 19 |
| Intervention Group | 8 |
1 review available for fentanyl and Hypothermia
| Article | Year |
|---|---|
Safety profile of anesthetic modalities during laser treatment for retinopathy of prematurity: a systematic review.
Topics: Anesthetics; Child; Fentanyl; Humans; Hypothermia; Infant; Infant, Newborn; Ketamine; Lasers; Midazo | 2023 |
4 trials available for fentanyl and Hypothermia
| Article | Year |
|---|---|
Comparison of forced-air warming systems in prevention of intraoperative hypothermia.
Topics: Abdomen; Adult; Air; Anesthesia, General; Bedding and Linens; Body Temperature; Crystalloid Solution | 2018 |
Effect of transdermally administered fentanyl on minimum alveolar concentration of isoflurane in normothermic and hypothermic dogs.
Topics: Administration, Cutaneous; Analgesics, Opioid; Anesthetics, Inhalation; Animals; Body Temperature; C | 2006 |
Predictors of hypothermia during spinal anesthesia.
Topics: Aged; Aging; Analysis of Variance; Anesthesia, Spinal; Anesthetics, Intravenous; Anesthetics, Local; | 2000 |
IM droperidol as premedication attenuates intraoperative hypothermia.
Topics: Adjuvants, Anesthesia; Adult; Anesthetics, Intravenous; Body Temperature; Droperidol; Female; Fentan | 2001 |
21 other studies available for fentanyl and Hypothermia
| Article | Year |
|---|---|
Fentanyl analgesia in asphyxiated newborns treated with therapeutic hypothermia.
Topics: Analgesia; Asphyxia Neonatorum; Fentanyl; Humans; Hypothermia; Hypothermia, Induced; Hypoxia-Ischemi | 2022 |
Xylazine effects on opioid-induced brain hypoxia.
Topics: Analgesics, Opioid; Animals; Drug Overdose; Fentanyl; Heroin; Humans; Hypothermia; Hypoxia; Hypoxia, | 2023 |
Evidence for nonlinear accumulation of the ultrapotent fentanyl analog, carfentanil, after systemic administration to male rats.
Topics: Analgesics, Opioid; Animals; Catalepsy; Chromatography, High Pressure Liquid; Fentanyl; Half-Life; H | 2019 |
The impact of perioperative warming in an outpatient aesthetic surgery setting.
Topics: Adult; Ambulatory Surgical Procedures; Analgesics, Opioid; Anesthesia Recovery Period; Bedding and L | 2012 |
Morphine and d-amphetamine nullify each others' hypothermic effects in mice.
Topics: Analgesics, Opioid; Animals; Dextroamphetamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Do | 2003 |
The effect of hypothermia on myogenic motor-evoked potentials to electrical stimulation with a single pulse and a train of pulses under propofol/ketamine/fentanyl anesthesia in rabbits.
Topics: Anesthesia, General; Anesthetics, Dissociative; Anesthetics, Intravenous; Animals; Blood Gas Analysi | 2003 |
[NEUROLEPTOANALGESIA AS A MEANS OF INDUCTION FOR MODERATE SURFACE HYPOTHERMIA].
Topics: Adolescent; Analgesics; Analgesics, Non-Narcotic; Anesthesia; Anesthesiology; Antipyretics; Benperid | 1964 |
[EXPERIMENTAL EVALUATION OF EFFECTS OF BARBITURATE ANESTHESIA AND NEUROLEPTOANALGESIA IN INDUCTION OF DEEP HYPOTHERMIA].
Topics: Analgesics; Analgesics, Non-Narcotic; Anesthesia; Antipyretics; Barbiturates; Benperidol; Fentanyl; | 1965 |
[ON SOME ELECTROCARDIOGRAPHIC MODIFICATIONS FOUND DURING MODERATE SURFACE HYPOTHERMIA IN NEUROLEPTOANALGESIA].
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Benperidol; Electrocardiography; Fentanyl; Heart | 1965 |
The effect of rectal temperature on perianesthetic serum concentrations of transdermally administered fentanyl in cats anesthetized with isoflurane.
Topics: Administration, Cutaneous; Anesthetics, Inhalation; Animals; Body Temperature; Cats; Fentanyl; Hypot | 2003 |
The effect of mild hypothermia on plasma fentanyl concentration and biotransformation in juvenile pigs.
Topics: Analgesics, Opioid; Animals; Biotransformation; Blood Gas Analysis; Blood Glucose; Blood Pressure; C | 2005 |
Preservation of static and dynamic cerebral autoregulation after mild hypothermic cardiopulmonary bypass.
Topics: Aged; Anesthetics, Combined; Blood Flow Velocity; Cardiopulmonary Bypass; Cerebral Arteries; Female; | 2005 |
Hypothermia after cesarean delivery and its reversal with lorazepam.
Topics: Adult; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Bupivaca | 2005 |
Hypothermia associated with subarachnoid morphine.
Topics: Adult; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Body Tem | 1997 |
Fentanyl analgesia increases the incidence of postoperative hypothermia in neonates.
Topics: Analgesia; Analgesia, Epidural; Analgesics, Opioid; Body Temperature Regulation; Bupivacaine; Fentan | 1998 |
[Anesthetic management of an extremely low birth weight neonate for two thoracic surgeries of patent ductus arterious and coarctation of the aorta].
Topics: Anesthesia, Intravenous; Aortic Coarctation; Ductus Arteriosus, Patent; Fentanyl; Humans; Hypothermi | 2000 |
Laparoscopic cholecystectomy: the anaesthetist's point of view.
Topics: Age Factors; Anesthesia; Anesthesia Recovery Period; Anesthesia, Intravenous; Antiemetics; Cholecyst | 1992 |
Postbypass hypothermia and its relationship to the energy balance of cardiopulmonary bypass.
Topics: Anesthesia, Intravenous; Anesthetics; Body Temperature; Cardiopulmonary Bypass; Energy Transfer; Eto | 1991 |
Cessation of shivering and hypothermia associated with epidural sufentanil.
Topics: Adult; Analgesia, Epidural; Cesarean Section; Double-Blind Method; Female; Fentanyl; Humans; Hypothe | 1989 |
Fentanyl and hypothermia.
Topics: Diabetes Insipidus; Fentanyl; Humans; Hypothermia | 1989 |
The clinical efficiency of the Portex in-line blood warmer.
Topics: Anesthesia, General; Blood Preservation; Blood Transfusion; Cold Temperature; Enflurane; Fentanyl; H | 1986 |