Page last updated: 2024-10-27

fentanyl and Hyperventilation

fentanyl has been researched along with Hyperventilation in 10 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Hyperventilation: A pulmonary ventilation rate faster than is metabolically necessary for the exchange of gases. It is the result of an increased frequency of breathing, an increased tidal volume, or a combination of both. It causes an excess intake of oxygen and the blowing off of carbon dioxide.

Research Excerpts

ExcerptRelevanceReference
" Calculation of the pharmacokinetic parameters from the derived compartmental models demonstrated an increased total volume of distribution of sufentanil in hypocapnic patients (mean 5427 (SD 1866) ml kg-1 v."5.28Pharmacokinetics of sufentanil in neurosurgical patients undergoing hyperventilation. ( Matteo, RS; Ornstein, E; Schwartz, AE; Thornhill, M; Young, WL, 1989)
"The study indicates that before as well as during hyperventilation, subdural ICP and AVDo2 are lower and CPP higher in propofol-anesthetized patients compared with patients anesthetized with isoflurane or sevoflurane."5.10Intracranial pressure and cerebral hemodynamic in patients with cerebral tumors: a randomized prospective study of patients subjected to craniotomy in propofol-fentanyl, isoflurane-fentanyl, or sevoflurane-fentanyl anesthesia. ( Cold, GE; Hauerberg, J; Holst, P; Landsfeldt, U; Mau, S; Olsen, KS; Petersen, CB; Petersen, KD, 2003)
" Calculation of the pharmacokinetic parameters from the derived compartmental models demonstrated an increased total volume of distribution of sufentanil in hypocapnic patients (mean 5427 (SD 1866) ml kg-1 v."1.28Pharmacokinetics of sufentanil in neurosurgical patients undergoing hyperventilation. ( Matteo, RS; Ornstein, E; Schwartz, AE; Thornhill, M; Young, WL, 1989)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19905 (50.00)18.7374
1990's3 (30.00)18.2507
2000's2 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Petersen, KD1
Landsfeldt, U1
Cold, GE1
Petersen, CB1
Mau, S1
Hauerberg, J1
Holst, P1
Olsen, KS1
Adachi, YU1
Sano, H1
Doi, M1
Sato, S1
Brenet, O1
Granry, JC1
Poirier, N1
Le Gall, R1
Misfeldt, BB1
Jörgensen, PB1
Spotoft, H1
Ronde, F1
Algotsson, L1
Messeter, K1
Rosén, I1
Holmin, T1
Tobias, JD1
Heideman, RL1
Schwartz, AE1
Matteo, RS1
Ornstein, E1
Young, WL1
Thornhill, M1
Darbinyan, TM1
Barker, J1
Jennett, WB1
Catton, DV1
Browne, RA1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Influence of Vasopressors on Brain Oxygenation and Microcirculation in Anesthetized Patients With Cerebral Tumors[NCT02713087]Phase 448 participants (Actual)Interventional2015-09-30Completed
Impact of Totally Transdermal Sedation in the Weaning From Remifentanil Infusion Among Critically Ill Patients Undergoing Mechanical Ventilation: a Pilot Randomized-controlled Study (The TOES Trial)[NCT04204967]Phase 224 participants (Anticipated)Interventional2021-02-15Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for fentanyl and Hyperventilation

ArticleYear
Intracranial pressure and cerebral hemodynamic in patients with cerebral tumors: a randomized prospective study of patients subjected to craniotomy in propofol-fentanyl, isoflurane-fentanyl, or sevoflurane-fentanyl anesthesia.
    Anesthesiology, 2003, Volume: 98, Issue:2

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Anesthesia, Inhalation; Anesthetics, Inhalation; Anest

2003
The effects of droperidol and fentanyl on intracranial pressure and cerebral perfusion pressure in neurosurgical patients.
    British journal of anaesthesia, 1976, Volume: 48, Issue:10

    Topics: Adult; Blood Pressure; Carbon Dioxide; Central Venous Pressure; Cerebrovascular Circulation; Clinica

1976

Other Studies

8 other studies available for fentanyl and Hyperventilation

ArticleYear
Central neurogenic hyperventilation treated with intravenous fentanyl followed by transdermal application.
    Journal of anesthesia, 2007, Volume: 21, Issue:3

    Topics: Administration, Cutaneous; Analgesics, Opioid; Blood Gas Analysis; Brain Neoplasms; Fatal Outcome; F

2007
-The effect of desflurane on cerebral blood flow velocity and cerebrovascular reactivity to CO2 in children-.
    Annales francaises d'anesthesie et de reanimation, 1998, Volume: 17, Issue:3

    Topics: Adult; Analysis of Variance; Anesthetics, Inhalation; Anesthetics, Intravenous; Blood Flow Velocity;

1998
Effects of nitrous oxide on cerebral haemodynamics and metabolism during isoflurane anaesthesia in man.
    Acta anaesthesiologica Scandinavica, 1992, Volume: 36, Issue:1

    Topics: Adult; Anesthesia, Inhalation; Brain; Carbon Dioxide; Cerebrovascular Circulation; Electroencephalog

1992
Primary central hyperventilation in a child with a brainstem glioma: management with continuous intravenous fentanyl.
    Pediatrics, 1991, Volume: 88, Issue:4

    Topics: Brain Neoplasms; Brain Stem; Child; Fentanyl; Glioma; Humans; Hyperventilation; Infusions, Intraveno

1991
Pharmacokinetics of sufentanil in neurosurgical patients undergoing hyperventilation.
    British journal of anaesthesia, 1989, Volume: 63, Issue:4

    Topics: Adult; Analgesics, Opioid; Brain; Carbon Dioxide; Female; Fentanyl; Half-Life; Humans; Hyperventilat

1989
The use of neuroleptanalgesia for induction of anesthesia.
    International anesthesiology clinics, 1973,Fall, Volume: 11, Issue:3

    Topics: Acid-Base Equilibrium; Adolescent; Adult; Aged; Blood Pressure; Calcium Chloride; Cardiac Output; Ch

1973
Neuroleptanalgesia for cerebral blood flow studies in patients undergoing carotid ligation.
    Acta anaesthesiologica Scandinavica. Supplementum, 1966, Volume: 24

    Topics: Anesthesia, Local; Aneurysm; Carbon Dioxide; Carotid Artery Diseases; Cerebrovascular Circulation; E

1966
Innovar as an adjunct to nitrous oxide, oxygen, curare anaesthesia.
    Canadian Anaesthetists' Society journal, 1971, Volume: 18, Issue:2

    Topics: Adjuvants, Anesthesia; Adult; Aged; Anesthesia, Inhalation; Benperidol; Female; Fentanyl; Heart Rate

1971