Page last updated: 2024-10-27

fentanyl and Huntington Disease

fentanyl has been researched along with Huntington Disease in 3 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Huntington Disease: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)

Research Excerpts

ExcerptRelevanceReference
"Two patients with Huntington's chorea were anaesthetized successfully with a technique including thiopentone, nitrous oxide and either a narcotic analgesic or halothane; pancuronium was employed for myoneural blockade."1.26Anaesthesia and Huntington's chorea. A report of two cases. ( Farina, J; Rauscher, LA, 1977)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nguyen, PT1
Meeks, D1
Liotiri, D1
Mitra, S1
Sharma, K1
Arora, S1
Deva, C1
Gombar, KK1
Farina, J1
Rauscher, LA1

Other Studies

3 other studies available for fentanyl and Huntington Disease

ArticleYear
Anaesthesia and orphan disease: airway and anaesthetic management in Huntington's disease.
    BMJ case reports, 2017, Oct-19, Volume: 2017

    Topics: Androstanols; Anesthesia, General; Anesthetics, Intravenous; Female; Fentanyl; Gastrostomy; Humans;

2017
Repeat anesthetic management of a patient with Huntington's chorea.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2001, Volume: 48, Issue:9

    Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Elective Surgical Procedures; Female; Fentanyl; H

2001
Anaesthesia and Huntington's chorea. A report of two cases.
    British journal of anaesthesia, 1977, Volume: 49, Issue:11

    Topics: Anesthesia, Endotracheal; Female; Fentanyl; Halothane; Humans; Huntington Disease; Male; Middle Aged

1977